Clinical trials: Pseudotumor Cerebri, open to volunteers
Idiopathic Intracranial Hypotension, Venous Sinus Stenosis
Stent Implantation Versus Medical Therapy for Idiopathic IntracraniaL Hypertension (SIMPLE)
The aim of this study is to assess the efficacy of stent implantation versus medical therapy on idiopathic intracranial hypertension with venous sinus stenosis.
- Trial name
- NCT05707442
- Testing
- Stent Implantation, Acetazolamide-based medical therapy, Weight loss
- Where
- China
- Volunteers
- 74 people
- Sponsor
- Beijing Tiantan Hospital
Pseudotumor Cerebri
Multifocal Chromatic Pupilloperimetry in Patients With Pseudotumor Cerebri and Healthy Subjects.
PTC(Pseudotumor cerebri) patients may develop increased Intracranial pressure (ICP) that can produces increased pressure around the distal optic nerve,which is likely followed by venule compression, ischemia, and loss of visual…
- Trial name
- NCT03304314
- Testing
- objective chromatic multifocal pupillometer
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
IIH - Idiopathic Intracranial Hypertension
IIH Intervention: A Clinical Trial Comparing 2 Treatments (Shunts and Stents) Evaluation Of Clinical Effectiveness And Cost Effectiveness
Background and study aims Idiopathic intracranial hypertension (IIH) is a neurological condition characterised by increased pressure inside the skull, called intracranial pressure (ICP).
- Trial name
- Intervention (NCT07440277)
- Testing
- CSF shunt, DVSS
- Where
- 15 sites in United Kingdom
- Volunteers
- 80 people
- Sponsor
- University of Birmingham
Idiopathic Intracranial Hypertension (IIH)
Intracranial Venous Stenting Evaluation in Patients With Idiopathic Intracranial Hypertension in the Early Phase
This study is aimed at patients suffering from recently discovered intracranial hypertension, caracterized by visual loss, chronic headache and/or tinnitus.
- Trial name
- DIVE IIN EARLY (NCT06919744)
- Testing
- Best medical care, Intervention (stenting)
- Where
- 3 sites in France
- Volunteers
- 114 people
- Sponsor
- University Hospital, Montpellier
Idiopathic Intracranial Hypertension (IIH)
Stenting Of Symptomatic Cerebral siNus stenosIs With the laserCut Self-expanding SILANCE Stent
The objective of this clinical investigation is to evaluate and demonstrate the clinical benefit, performance, and safety of the SILANCE Stent, which is specifically designed for the treatment of patients with symptomatic sinus…
- Trial name
- SONIC (NCT07561268)
- Testing
- SILANCE Stent Implantation
- Volunteers
- 99 people
- Sponsor
- Acandis GmbH
Pseudotumor Cerebri, Cerebrospinal Fluid
Stenting Versus Neurosurgical Treatment of Idiopathic Intracranial Hypertension.
Idiopathic intracranial hypertension (HTICi) is a pathology, affecting young adults with a predominance of women, due to an increase in intracranial pressure, which may be associated with stenosis of the cerebral venous sinuses…
- Conditions
- Pseudotumor Cerebri, Cerebrospinal Fluid, Transverse Sinuses
- Trial name
- HYDROPTIC (NCT05050864)
- Testing
- venous sinus stenting, Neurosurgical internal ventricular shunt
- Where
- France
- Volunteers
- 276 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Idiopathic Intracranial Hypertension (IIH)
Venous Stenting Evaluation in Patients With Intracranial Hypertension Under Long-term Acetazolamide
This study is aimed at patients suffering from long term intracranial hypertension (caracterized by visual loss, chronic headache and/or tinnitus), receiving acetazolamide for more than 1 year, having inadequate response to…
- Trial name
- DIVEIINLATE (NCT06945848)
- Testing
- Acetazolamide, Stent (Tentos 4F or Precise ProRX)
- Where
- 3 sites in France
- Volunteers
- 114 people
- Sponsor
- University Hospital, Montpellier
Idiopathic Intracranial Hypertension, Intracranial Pressure Increase
Prospective Ocular Imaging for Intracranial Pressure Evaluation
This is a prospectively recruiting, database development study collecting images and videos of the spontaneous venous pulsation at the back of people's eyes - this is a pulse one can see on examination of the back of the eye…
- Conditions
- Idiopathic Intracranial Hypertension, Intracranial Pressure Increase, Spontaneous Venous Pulsations
- Trial name
- POICCP (NCT06855342)
- Where
- United Kingdom
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Benign Intracranial Hypertension
Diagnostic and Prognostic Biomarkers of Idiopathic Intracranial Hypertension
Idiopathic intracranial hypertension (IIH) is a condition of unknown etiology, primarily affecting overweight females of childbearing age.
- Trial name
- NCT04032379
- Testing
- Standard treatment
- Where
- 2 sites in Denmark
- Volunteers
- 300 people
- Sponsor
- Danish Headache Center
Idiopathic Intracranial Hypertension (IIH)
BMI in Idiopathic Intracranial Hypertension and Its Relationship With the Response to Treatment
1. To establish the correlation between the evolution of the body mass index in benign intracranial hypertension and the response to treatments. 2. To establish the BMI at which this disease occurs. 3.
- Trial name
- NCT06913712
- Testing
- Weight loss without pharmacotherapy
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- University of Valencia
Idiopathic Intracranial Hypertension (IIH)
Eptinezumab for Chronic Headache in Idiopathic Intracranial Hypertension
The goal of this clinical trial is to learn if eptinezumab can reduce headache frequency and headache-related disability in adults with idiopathic intracranial hypertension (IIH) and chronic headache.
- Trial name
- PRIMA (NCT07645833)
- Testing
- Eptinezumab
- Volunteers
- 96 people
- Sponsor
- Rigmor Højland Jensen
Idiopathic Intracranial Hypertension (IIH)
Tirzepatide in Idiopathic Intracranial Hypertension Trial
This will be a randomized, double-blind, parallel, placebo-controlled trial of 60 participants. The primary analysis will be a statistical comparison of the estimates of the mean difference in the 12-month change in intracranial…
- Trial name
- TIIHT (NCT07191873)
- Testing
- Tirzepatide
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Duke University
Idiopathic Intracranial Hypertension (IIH), Glymphatic System
Advanced Neuroimaging in Idiopathic Intracranial Hypertension
Idiopathic intracranial hypertension (IIH) is characterized by elevated intracranial pressure leading to symptoms like papilledema, headache, and cognitive dysfunction.
- Trial name
- IIH (NCT06950099)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Thomas Jefferson University
Idiopathic Intracranial Hypertension (IIH)
Dural Venous Sinus Stent in Idiopathic Intracranial Hypertension
This study aims to identify clinical determinants and factors that predict outcome including primary outcome and secondary outcome depending on factors in individual patients with Idiopathic intracranial hypertension treated by…
- Trial name
- NCT06833424
- Testing
- Dural venous sinus stenting
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Idiopathic Intracranial Hypertension
Multimodal MRI Assessment of Brain Fluid Circulation in Idiopathic Intracranial Hypertension
Idiopathic intracranial hypertension (IIH) is a neurological disorder characterized by increased pressure inside the skull without an identifiable cause.
- Trial name
- NCT07915453
- Where
- China
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital