Clinical trials: Psoriasis Patients
Psoriasis, Metabolic Syndrome
Methotrexate Versus Secukinumab Safety in Psoriasis Patients With Metabolic Syndrome
A prospective, controlled, open trial in psoriasis patients with metabolic syndrome, candidate to methotrexate or secukinumab was conducted between January 2019 and May 2020.
- Trial name
- NCT04469829
- Testing
- Secukinumab, Methotrexate
- Where
- Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Psoriasis
Evaluate Whether Combination Therapy With Methotrexate and Raptiva in Psoriasis Patients is Safe and Increases Efficacy
To evaluate whether a short-term course of methotrexate in patients treated with efalizumab (Raptiva) increases efficacy. The secondary objectives of this study are 1) to evaluate the efficacy of Raptiva in maintaining the…
- Trial name
- NCT00368654
- Testing
- Methotrexate, Raptiva
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Psoriatic Arthritis, Foot Arthritis
Effect of Custom Foot Orthoses in Patients With Psoriatic Arthritis
Foot involvement is a major concern in psoriatic arthritis (PsA). The patients could experience severe levels of foot pain and disability and reduced mobility and quality of life.
- Trial name
- NCT05075343
- Testing
- Custom foot orthoses
- Where
- 2 sites in Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Patrick Boissy
Psoriasis
Monitoring and Modifying Atherosclerosis in Psoriasis Patients Study
The main aims of this study are to determine whether: a) psoriasis patients with or without arthritis have more cardiovascular inflammation than healthy subjects and b)3 months of etanercept (enbrel) therapy (prescribed to…
- Trial name
- MMAPPS (NCT01522742)
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Psoriatic Arthritis
Evaluation of Sarcopenia and Related Factors in Patients Diagnosed With Psoriatic Arthritis
The purpose of the study is identify the prevalence of sarcopenia and its associated factors in patients with psoriatic arthritis.
- Trial name
- NCT06437392
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Psoriasis
The Inner Ear Function in Psoriatic Patients
Psoriasis in a systemic disease that effects many systems of the body. few studies examined the hearing function of these patients but the results were inconclusive.
- Trial name
- MP (NCT03865030)
- Testing
- audiovestibular function
- Where
- Israel
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Arthritis, Psoriatic, Healthy
A Study of Guselkumab and Risankizumab in Healthy Participants and Participants With Psoriatic Arthritis
The purpose of this study is to assess the tissue distribution of guselkumab and risankizumab in healthy participants (Part 1) and psoriatic arthritis (PsA) participants (Part 2 and Part 3).
- Trial name
- NCT05083078
- Testing
- Guselkumab, Risankizumab
- Where
- Austria
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Psoriasis Vulgaris
Hormonal Associations in Male Patients With Psoriasis Vulgaris
A cross sectional clinical study will be conducted on male patients with moderate and sever psoriasis vulgaris to: Identify the pattern of serum testosterone level and tissue androgen receptors.
- Trial name
- NCT05716152
- Testing
- Morning blood sample and skin punch biopsy of 4 mm diameter.
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Sohag University
Psoriasis
A Study of the Safety and Efficacy of Infliximab in Patients With Psoriasis
The purpose of this study is to determine if infliximab (anti-TNF) is effective in the treatment of plaque psoriasis.
- Trial name
- NCT00106834
- Testing
- Infliximab
- Volunteers
- 378 people, healthy volunteers welcome
- Sponsor
- Centocor, Inc.
Psoriasis, Anti Mullerian Hormone
Ovarian Reserve in Patients With Psoriasis
Psoriasis is a common autoimmune disease. It affects women of all ages including reproductive years. Autoimmune diseases including psoriasis are linked to premature ovarian reserve.
- Conditions
- Psoriasis, Anti Mullerian Hormone, Ovarian Reserve
- Trial name
- NCT03492632
- Testing
- Hormone panel
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Plaque Psoriasis
Efficacy and Safety of Enstilar Foam in Combination With Apremilast (Otezla) in Patients With Moderate Plaque Psoriasis
This study seeks to show whether there is a benefit of prescribing Enstilar with Otezla in the treatment of patients with moderate plaque type psoriasis.
- Trial name
- NCT03441789
- Testing
- Enstilar, Vehicle, Otezla
- Where
- 4 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- L.H. Kircik, M.D.
Psoriasis
Phase I Study of GN-037 Cream for Psoriasis
In this Phase I study, three different doses (low, medium and high dose, on the basis of surface area applied) of GN-037 cream (12 volunteers in total) and placebo (6 volunteers in total) will be administered to healthy…
- Trial name
- NCT05428202
- Testing
- GN037
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Psoriasis
Study on the Therapeutic Mechanisms of Dithranol Treatment in Patients With Chronic Plaque Psoriasis
Dithranol (known in the U.S.A. as anthralin and in Germany as cignolin) is one of the oldest and safest topical anti-psoriatic treatments.
- Trial name
- NCT02752672
- Where
- Austria
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Psoriasis, Melanoma
Can We Miss Pigmented Lesions in Psoriasis Patients?
In psoriasis patients, thick psoriatic plaques can obscure these lesions, and clinicians rely heavily on visual inspection to recognize suspicious or atypical pigmented lesions.
- Conditions
- Psoriasis, Melanoma, Non-melanoma Skin Cancer
- Trial name
- NCT01053819
- Testing
- etanercept
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Scalp Psoriasis
Phase III Clinical Study in Patients With Mild to Severe Scalp Psoriasis
A Randomized, Double-Blind, Vehicle-Controlled, Parallel-Design, Multiple-Site, Phase III Clinical Study to Evaluate the Efficacy and Safety of DSXS topical product in Patients with Mild to Severe Scalp Psoriasis
- Trial name
- NCT02933866
- Testing
- DSXS topical, Vehicle topical
- Where
- United States
- Volunteers
- 371 people, healthy volunteers welcome
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Psoriasis, Psoriatic Arthritis
IKBKB Gene Polymorphism (Single Nucleotide Polymorphism) (SNP) in Psoriatic and Psoriatic Arthritis Patients
Psoriasis is a chronic inflammatory skin disease characterized by scaly indurated erythema. It impairs patients' quality of life enormously. Psoriasis refers to a persistent inflammatory illness of the skin and joints.
- Trial name
- NCT06729463
- Testing
- Humira
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- South Valley University
Psoriasis Vulgaris, Psoriatic Arthritis
Impact of Decision-Framing in Psoriasis
Rationale: Shared decision-making models between clinicians and patients are critical to improving healthcare delivery and adherence to medication. One type of model, decision framing, is rarely studied in medicine.
- Conditions
- Psoriasis Vulgaris, Psoriatic Arthritis, Psoriasis
- Trial name
- NCT04136314
- Testing
- Decision-Framed Survey
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Plaque Psoriasis
The Effect of Enstilar Versus Vehicle on Target Lesions in Moderate Plaque Type Psoriasis Patients
This study seeks to show whether there is a benefit of prescribing Enstilar in the treatment of patients with moderate plaque type psoriasis. Subjects will receive study treatment of Enstilar foam.
- Trial name
- NCT03848871
- Testing
- Enstilar
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Derm Research, PLLC
Psoriasis Vulgaris
Glucose Trnsporter and PEDF in Psoriasis
Psoriasis is a chronic relapsing cutaneous immune mediated inflammatory disease(IMID). In which there are skin lesions characterized by erythema, thickness and scale formation with different size from a pinhead to 20 cm in…
- Trial name
- NCT04242082
- Testing
- GLUT 1 gene expression
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Assiut University
Psoriasis
Double-Blind Study of Topical WBI-1001 Cream on Patients With Psoriasis
The purpose of this study is to evaluate primarily the safety and tolerability and secondarily the efficacy of topically applied WBI-1001 cream in patients with mild to moderate psoriasis.
- Trial name
- WBI-1001-101 (NCT00830817)
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Welichem Biotech Inc.