Clinical trials: Psoriasis Patients
Psoriasis Vulgaris
Therapeutic Drug Monitoring of Risankizumab in Psoriasis Patients (BIOLOPTIM-RIS)
Biologics such as risankizumab are currently the most effective treatment option for patients with moderate to severe psoriasis.
- Trial name
- BIOLOPTIM-RIS (NCT05685940)
- Testing
- Venapuncture, Patient questionnaires
- Where
- 7 sites in Belgium
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent
Psoriasis Vulgaris, Autophagy
ATG5 as a Serum Marker of Autophagy in Psoriatic Patient
it will be of interest to know the ATG 5 as a serum marker of autophagy in serum of psoriasis vulgairs patients and explore its relationship with psoriasis severity.
- Trial name
- NCT05279638
- Testing
- serum ATG5
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sohag University
Plaque Psoriasis
Characteristics of Patients Treated With Secukinumab for Moderate to Severe Plaque Psoriasis
This study was a non-interventional, retrospective study collecting data from hospital medical records. Approximately 200 adult patients with moderate to severe plaque psoriasis who were treated with secukinumab from hospitals in…
- Trial name
- NCT05650060
- Testing
- Secukinumab
- Where
- Thailand
- Volunteers
- 163 people
- Sponsor
- Novartis Pharmaceuticals
Psoriasis
Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single and Repeat Topical Administration of BOS-475 in Healthy Subjects and Patients With Psoriasis
This study was conducted to evaluate the safety and tolerability of BOS-475 following single and repeat topical administration to healthy participants (Part A), and to evaluate the safety and tolerability of 42-day repeat topical…
- Trial name
- NCT03960450
- Testing
- BOS-475, Vehicle
- Where
- 3 sites in Australia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Boston Pharmaceuticals
Psoriasis
Assessing the Long Term Effectiveness and Safety of Biotherapies in the Treatment of Cutaneous Psoriasis
PSOBIOTEQ is a national multicentric prospective cohort of cutaneous psoriasis patients receiving systemic treatment (biotherapy or DMARDs) for moderate to severe cutaneous psoriasis.
- Trial name
- PSOBIOTEQ (NCT01617018)
- Where
- France
- Volunteers
- 4,613 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Plaque Psoriasis
Study to Evaluate PF-04965842 in Patients With Moderate to Severe Psoriasis
Study B7451005 is a Phase 2 study which will assess the efficacy and safety of PF-04965842 in patients with moderate to severe psoriasis.
- Trial name
- NCT02201524
- Testing
- PF-04965842
- Where
- 45 sites in United States, Canada
- Volunteers
- 59 people
- Sponsor
- Pfizer
Psoriasis
Safety and Efficacy Study of MM-093 in Patients With Chronic Plaque Psoriasis
Merrimack is conducting a research study to see if an experimental drug, called MM-093, is safe and effective in the treatment of psoriasis.
- Trial name
- NCT00147329
- Testing
- MM-093
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Merrimack Pharmaceuticals
Psoriasis
Studying the Effect of Methotrexate Alone Versus Methotrexate and Vitamin D on the Cardiovascular Risk of Psoriatic Patients
The prevalence of cardiovascular risk in psoriasis has been reported in previous studies.Various studies have also shown that systemic treatments for psoriasis, including methotrexate, may significantly decrease this…
- Trial name
- NCT03904680
- Testing
- Methotrexate, Vitamin D
- Volunteers
- 30 people
- Sponsor
- Cairo University
Rheumatoid Arthritis, Psoriatic Arthritis
Endothelial Function, Inflammatory Disease Activity, and Bone and Cartilage Markers in Rheumatic Patients: The Influence of Antirheumatic Treatment
The aim of this study is to examine the associations between inflammatory disease activity and endothelial function in rheumatoid arthritis (RA) and spondyloarthritis patients treated with methotrexate and Tumor Necrosis Factor…
- Conditions
- Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis, Endothelial Dysfunction
- Trial name
- PSARA (NCT00902005)
- Where
- Norway
- Volunteers
- 145 people
- Sponsor
- Revmatismesykehuset AS
Psoriasis, Atopic Dermatitis
Involvement of Pollutants in Atopic Dermatitis and Psoriasis
Introduction Pollution is a significant public health issue. Research has shown a positive correlation between air pollution and chronic inflammatory dermatoses, including psoriasis and eczema.
- Trial name
- DIAhR (NCT06213688)
- Testing
- blood sampling, urine sampling
- Volunteers
- 64 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Arthritis, Psoriatic, Metabolic Syndrome
The DIET Trial - Dietetic Intervention in Psoriatic Arthritis
Psoriasis (Ps) and psoriatic arthritis (PsA) are associated with increased risk of metabolic syndrome (MetS), body fatness and cardiovascular risk.
- Trial name
- DIET (NCT03142503)
- Testing
- Diet + supplementation
- Volunteers
- 194 people
- Sponsor
- Federal University of São Paulo
Plaque Psoriasis
Efficacy Study Comparing Topical M518101 and Vitamin D3 in Adult Psoriasis Patients
M5181 - a novel vitamin D3 analogue - is currently under development for the treatment of plaque psoriasis and is being developed as a topical ointment formulation (M518101) Clinical and non-clinical studies indicate that M5181…
- Trial name
- NCT01989429
- Testing
- M518101
- Where
- 6 sites in Austria, Bulgaria and 4 more
- Volunteers
- 788 people
- Sponsor
- Maruho Europe Limited
Psoriasis
Long-Term Follow-Up Study of Psoriasis Patients
The purpose of this study is to evaluate the long-term safety and profile of psoriasis patients who have completed participation in a previous study and who received treatment with MEDI-507.
- Trial name
- NCT00131066
- Testing
- Follow up from previous treatment with MEDI-507
- Where
- 21 sites in United States, Belgium and 4 more
- Volunteers
- 200 people
- Sponsor
- MedImmune LLC
Plaque Psoriasis, Fibromyalgia
Prevalence of Fibromyalgia in Patients With Plaque Psoriasis
This observational study aims to determine how common fibromyalgia syndrome and central sensitization are in adults with plaque psoriasis compared to healthy individuals.
- Trial name
- NCT07773766
- Volunteers
- 110 people
- Sponsor
- Assiut University
Traditional Chinese Medicine, Drug Effect
Comparison of PSORI-CM01 Formula vs Gu Ben Hua Yu Formula Combined With AD-MSCs in Psoriasis
The purpose of this study is to evaluate and compare the safety and efficacy of PSORI-CM01 formula vs Gu Ben Hua Yu formula combined with Expanded Allogeneic AD-MSCs in patients with moderate to severe psoriasis.
- Conditions
- Traditional Chinese Medicine, Drug Effect, Drug Safety, Psoriasis
- Trial name
- NCT04785027
- Testing
- PSORI-CM01 formula, Gu Ben Hua Yu formula, adipose-derived multipotent mesenchymal stem cells
- Where
- China
- Volunteers
- 16 people
- Sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine
Generalized Pustular Psoriasis
A Study to Test Whether Spesolimab Helps People With Generalized Pustular Psoriasis (GPP) Who Need Treatment for Repeated Flares
This study is open to adults with a serious skin disease called generalized pustular psoriasis (GPP) who have repeated flares of GPP.
- Trial name
- NCT06013969
- Testing
- Spesolimab
- Where
- 35 sites in United States, Australia and 15 more
- Volunteers
- 42 people
- Sponsor
- LEO Pharma
Plaque Psoriasis
A Study to Assess Patient-Reported Wellbeing Using Tildrakizumab in a Live Setting
The main purpose of this study to investigate the relationship between clinical symptoms and quality of life (QoL) in participants who receive Tildrakizumab in the frame of clinical routine for the treatment of moderate to severe…
- Trial name
- NCT06488170
- Testing
- Tildrakizumab
- Where
- 7 sites in Czechia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Almirall, S.A.
Plaque Psoriasis
A 16-week Randomized Evaluation of the Impact of Mind.Px Application on Response to Biologic Treatment in Patients Suffering From Plaque Psoriasis Through Clinical Utility and Health Outcomes.
This protocol describes randomized, multicenter, blinded (subjects), 16-week, controlled study in parallel balanced groups of psoriasis (Ps) patients to evaluate the impact of Mind.Px on response to biologic treatments.
- Trial name
- MATCH (NCT05036889)
- Testing
- Mind.Px Report
- Volunteers
- 200 people
- Sponsor
- Mindera Health
Psoriasis
Icotinib Hydrochloride Cream in Healthy Adults and Psoriasis Patients
This is a phase I study to evaluate the safety, tolerability and pharmacokinetics of Icotinib Hydrochloride Cream in healthy adults and patients with mild to moderate psoriasis.
- Trial name
- NCT02574091
- Testing
- 1% icotinib hydrochloride cream, 2% icotinib hydrochloride cream
- Where
- New Zealand
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Betta Pharmaceuticals Co., Ltd.
Psoriasis
ACT-128800 in Patients With Moderate to Severe Chronic Plaque Psoriasis
This study will assess the efficacy, safety and tolerability of two doses of ACT 128800 in patients with moderate-to-severe chronic plaque psoriasis.
- Trial name
- NCT01208090
- Testing
- ACT-128800
- Where
- 67 sites in Austria, Belgium and 15 more
- Volunteers
- 326 people
- Sponsor
- Actelion
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