Clinical trials: Psoriasis Patients
Moderate-to-Severe Plaque Psoriasis
A Phase 2 Study of Jaktinib in Participants With Moderate to Severe Psoriasis
This is study designed to investigate the efficacy and safety of Jaktinib in the treatment of participants with moderate to severe, chronic plaque psoriasis as assessed by the Psoriasis Area and Severity Index (PASI) score and…
- Trial name
- PSO (NCT04612699)
- Testing
- Jaktinib
- Where
- China
- Volunteers
- 123 people
- Sponsor
- Suzhou Zelgen Biopharmaceuticals Co.,Ltd
Psoriasis
A Study of Otezla® in Patients With Plaque Psoriasis Under Routine Conditions
The objective of this NIS is the collection of data on the utilization of Apremilast under routine conditions in Germany. Patients' quality-of-life and treatment satisfaction on treatment with Apremilast in daily practice will be…
- Trial name
- NCT02626793
- Where
- 96 sites in Germany
- Volunteers
- 391 people
- Sponsor
- Amgen
Plaque Psoriasis
Use of Apremilast in Patients Who Are Dissatisfied With Stable Maintenance Topical Therapy
Sixteen week open label study of apremilast in combination with topical steroids with a four week safety follow up visit.
- Trial name
- NCT03000309
- Testing
- Apremilast
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Derm Research, PLLC
Plaque Psoriasis, Crohn's Disease
Adalimumab-psoriasis and Small Bowel Lesions
This study will determine the prevalence of small bowel lesions suggestive of Crohn's disease (CD) in patients with moderate to severe plaque psoriasis using capsule endoscopy.
- Trial name
- NCT01556672
- Testing
- Adalimumab, Capsule endoscopy
- Where
- 3 sites in Canada
- Volunteers
- 100 people
- Sponsor
- Innovaderm Research Inc.
Chronic Plaque Psoriasis
To Check Comparison of Apremilast and Methotrexate Efficacy in Patients With Moderate to Severe Plaque Psoriasis Presented to Tertiary Care Hospital
This study aims to compare efficacy of methotrexate vs apremilast in the management of chronic plaque psoriasis.Given the high prevalence of psoriasis in Pakistan and the significant psychological impact on patients, particularly…
- Trial name
- NCT07337434
- Testing
- Methotrexate, Apremilast
- Where
- Pakistan
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Syeda Sana Zaman
Atopic Dermatitis, Psoriasis
Skin Microbial Ecology in Atopic Dermatitis
Everybody's skin has bacteria that normally lives on it. Previous research has shown that people with eczema (or atopic dermatitis [AD]) have much higher concentrations of a certain bacteria (S.
- Conditions
- Atopic Dermatitis, Psoriasis, Healthy
- Trial name
- NCT04170244
- Testing
- AD subject visit sampling procedures, PS subject visit sampling procedures, Healthy control visit sampling procedures
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Psoriasis, Metabolic Syndrome
Effect of Vitamin D Supplementation on Metabolic Parameters of Patients With Psoriasis
The purpose of this study is to determine whether supplementation with oral vitamin D (cholecalciferol) improves metabolic parameters in patients with moderate to severe psoriasis.
- Conditions
- Psoriasis, Metabolic Syndrome, Vitamin D Deficiency
- Trial name
- NCT02271971
- Testing
- Vitamin D3
- Where
- Chile
- Volunteers
- 39 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Eczema, Psoriasis
Use of a Digital Psychotherapeutic App to Reduce Symptom Burden in Dermatology Patients
Skin diseases, despite low mortality, significantly impair quality of life. This randomised controlled trial evaluates the efficacy of a digital toolkit comprising psychotherapeutic strategies in reducing QoL burden in patients…
- Conditions
- Eczema, Psoriasis, Urticaria
- Trial name
- NCT06702293
- Testing
- Digital psychotherapeutic intervention, Healthy365
- Where
- Singapore
- Volunteers
- 690 people
- Sponsor
- National University Hospital, Singapore
Psoriasis
An Open-label Study to Evaluate the Efficacy of Re-treatment for Patients With a History of Etanercept Use
The purpose of this study is to evaluate the efficacy of re-treatment with etanercept 50mg subcutaneous injections twice weekly for 12 weeks in subjects who have previously been treated etanercept and efficacy diminished.
- Trial name
- ENBRECAP2009 (NCT01132235)
- Testing
- etanercept
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Florida Academic Dermatology Centers
Moderate to Severe Palmar Plantar Psoriasis
Efficacy and Safety of Ustekinumab in Patients With Moderate to Severe Palmar Plantar Psoriasis
The purpose of this study is to determine the short and long term safety and effectiveness of ustekinumab in subjects with moderate to severe chronic palmar plantar psoriasis.
- Trial name
- PPP (NCT01090063)
- Testing
- Ustekinumab
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Tufts Medical Center
Psoriasis Vulgaris
An Observational Study to Assess Patient Satisfaction and Control of Psoriasis With Calcipotriene/Betamethasone Dipropionate (Taclonex®) Topical Suspension, and Effect on Quality of Life
The purpose of this study is to document quality of life, patient satisfaction, effect on itching, and control of psoriasis vulgaris associated with use of calcipotriene/betamethasone dipropionate (Taclonex®) topical suspension…
- Trial name
- NCT01982552
- Where
- 12 sites in United States
- Volunteers
- 147 people
- Sponsor
- LEO Pharma
Psoriasis With Cell-derived Microparticles
The Difference of Microparticles in Patients With Psoriasis Vulgaris Who Received Stelara(Ustekinumab)
Background: Psoriasis, a common inflammatory disease, is associated with atherosclerotic vascular diseases, including stroke, myocardial infarction, and impaired microcirculations, among which circulating microparticles play an…
- Trial name
- NCT02693470
- Testing
- Ustekinumab
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Psoriasis
Safety of FURESTEM-CD Inj. in Patients With Moderate to Severe Plaque-type Psoriasis
Phase I clinical trial to evaluate safety of FURESTEM-CD Inj. in patients with moderate to severe in plaque-type psoriasis injection for 4weeks.
- Trial name
- NCT02918123
- Testing
- FURESTEM-CD Inj.
- Where
- South Korea
- Volunteers
- 9 people
- Sponsor
- Kang Stem Biotech Co., Ltd.
Psoriasis
A Study Comparing the Risk of Serious Infections and Malignancies With Deucravacitinib or Biologics in Japanese Patients With Psoriasis
The purpose of this study is to further evaluate the safety of deucravacitinib treatment in Japanese patients with psoriasis in the real-world setting
- Trial name
- NCT06952465
- Testing
- Deucravacitinib, Any biologic treatment for psoriasis
- Where
- 2 sites in Japan
- Volunteers
- 2,000 people
- Sponsor
- Bristol-Myers Squibb
Psoriasis, Vascular Inflammation
Effect of Adalimumab on Vascular Inflammation in Patients With Moderate to Severe Plaque Psoriasis
This study is to determine the effect of adalimumab on inflammation of blood vessels that could lead to heart attack in patients with psoriasis.
- Conditions
- Psoriasis, Vascular Inflammation, Coronary Atherosclerosis
- Trial name
- NCT00940862
- Testing
- adalimumab, UVB Phototherapy, Topical treatment
- Where
- 2 sites in Canada
- Volunteers
- 30 people
- Sponsor
- Innovaderm Research Inc.
Psoriasis
A Priming Intervention to Increase Patient Willingness to Use Injectables for the Management of Psoriasis
Biologic medications have revolutionized the treatment of inflammatory diseases such as moderate-to-severe psoriasis. Though very effective with an excellent safety profile, patients may be apprehensive about choosing a biologic…
- Trial name
- NCT03465696
- Testing
- Group #2 (Intervention), Group #3 (Intervention)
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Wake Forest University Health Sciences
Psoriasis
Transitioning From Cyclosporine to Alefacept in Psoriasis
The purpose of this study is to devise a safe and effective method for transitioning patients from cyclosporine to alefacept.
- Trial name
- NCT00143806
- Testing
- Transitioning patients from cyclosporine to alefacept
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Plaque Psoriasis
A Phase 2 Study of ZL-1102 in Patients With Chronic Plaque Psoriasis
A Randomized, Double-Blind, Vehicle-Controlled, Multicenter, Dose-Ranging, Phase 2 Study to Evaluate the Efficacy and Safety of Different Doses of ZL-1102 Topical gel (A Human VH IL-17A Antibody Fragment) in the Treatment of…
- Trial name
- NCT06380907
- Testing
- ZL-1102 1% w/w gel BID for 16 weeks, ZL-1102 3% w/w gel BID for 16 weeks, ZL-1102 3% w/w gel QD for 16 weeks
- Where
- 10 sites in Australia
- Volunteers
- 65 people
- Sponsor
- Zai Lab (Hong Kong), Ltd.
Psoriasis Vulgaris
Body PSOriasis: Long-term Relapse CONTROL
This non-interventional study of real-life clinical practice strategies for long-term relapse control in patients with psoriasis vulgaris is planned to enroll 650 adult patients from 60-100 Russian dermatology sites and follow…
- Trial name
- PSO-CONTROL (NCT03402828)
- Testing
- Any topical drug treatment
- Where
- Russia
- Volunteers
- 764 people
- Sponsor
- LEO Pharma
Plaque Psoriasis
A Phase IV Clinical Trial to Study the Safety, Tolerability and Efficacy of Tinefcon in Patients With Plaque Psoriasis
Psoriasis is a chronic inflammatory hyperproliferative disease of the skin affecting approximately 2% of the world's population.This phase IV study is planned to monitor performance of Tinefcon in patients suffering from…
- Trial name
- NCT01373567
- Testing
- TINEFCON
- Where
- 23 sites in India
- Volunteers
- 298 people
- Sponsor
- Piramal Enterprises Limited
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