Clinical trials: Psoriasis Patients
Psoriasis
Study Evaluating the Safety and Effectiveness of Etanercept for the Treatment of Pediatric Psoriasis
Psoriasis is a chronic, often severe, autoimmune condition that affects approximately 2% of the world's population. The epidemiology of pediatric psoriasis has not been well documented and no treatment guidelines exist for…
- Trial name
- PURPOSE (NCT01100034)
- Testing
- Etanercept
- Where
- 29 sites in France, Germany and 6 more
- Volunteers
- 72 people
- Sponsor
- Pfizer
Psoriasis
A Study of LY3316531 in Healthy Participants and in Participants With Psoriasis
The purpose of this study is to evaluate how well LY3316531 is tolerated and what side effects may occur in healthy participants and participants with psoriasis.
- Trial name
- NCT03418493
- Testing
- LY3316531 - IV, LY3316531 - SC
- Where
- 2 sites in United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Psoriasis
Evaluation of Etanercept in Patients With Plaque Psoriasis After Stopping Ciclosporin Therapy
The purpose of this study is to evaluate the use of etanercept as a replacement therapy for ciclosporin in patients with plaque psoriasis.
- Trial name
- NCT00581555
- Testing
- Etanercept
- Volunteers
- 120 people
- Sponsor
- Pfizer
Arthritis, Rheumatoid, Spondylitis, Ankylosing
One-year Persistence to Treatment of Participants Receiving Flixabi or Imraldi: a French Cohort Study
A study to describe the one-year persistence in participants treated by Flixabi (infliximab) or Imraldi (Adalimumab) as prescribed by the physician for each of the 5 following indications: Rheumatoid Arthritis (RA), Ankylosing…
- Conditions
- Arthritis, Rheumatoid, Spondylitis, Ankylosing, Arthritis, Psoriatic, Crohn's Disease
- Trial name
- PERFUSE (NCT03662919)
- Testing
- Infliximab, Adalimumab
- Where
- 60 sites in France
- Volunteers
- 2,274 people
- Sponsor
- Biogen
Carpal Tunnel Syndrome, Psoriatic Arthritis
Carpal Tunnel Syndrome in Patients With Psoriatic Arthritis
This study aimed to investigate median nerve hypervasculatitation in psoriatic arthritis (PsA) patients with CTS or without CTS by using SMI, then compare them with normal people.
- Trial name
- NCT05086029
- Testing
- Superb Microvascular Imaging
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Psoriasis
A Study to Test How Well Patients With Plaque Psoriasis Tolerate BI 730357 Over a Longer Period and How Effective it is
To assess long-term safety, tolerability, and efficacy of BI 730357 in patients with moderate to severe chronic plaque psoriasis.
- Trial name
- NCT03835481
- Testing
- BI 730357
- Where
- 30 sites in United States, Canada and 1 more
- Volunteers
- 165 people
- Sponsor
- Boehringer Ingelheim
Mesenchymal Stromal Cells, Psoriasis
Safety and Efficacy of Expanded Allogeneic AD-MSCs in Patients With Moderate to Severe Psoriasis
The purpose of this study is to evaluate the safety and efficacy of Adipose-derived Mesenchymal Stem Cells (AD-MSCs) with moderate to severe psoriasis. Any adverse events related to AD-MSCs infusion will be monitored.
- Conditions
- Mesenchymal Stromal Cells, Psoriasis, Drug Toxicity, Drug Effect
- Trial name
- ADMSP (NCT03265613)
- Testing
- adipose-derived multipotent mesenchymal stem cells
- Where
- China
- Volunteers
- 7 people
- Sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine
Psoriasis
Effect of Weight Loss on Psoriasis
Controlled data show that obesity is a risk factor for psoriasis and that psoriasis severity is correlated with the degree of overweight.
- Trial name
- NCT01137188
- Testing
- Low calorie diet
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- University Hospital, Gentofte, Copenhagen
Chronic Plaque Type Psoriasis
Efficacy of Secukinumab Compared to Ustekinumab in Patients With Plaque-type Psoriasis
This study assessed efficacy of secukinumab, compared to ustekinumab, in patients that have plaque-type psoriasis
- Trial name
- NCT02074982
- Testing
- AIN457 300 mg, ustekinumab 45/90 mg
- Where
- 137 sites in United States, Australia and 22 more
- Volunteers
- 676 people
- Sponsor
- Novartis Pharmaceuticals
Plaque Psoriasis
Comparison of CHS-0214 to Enbrel (Etanercept) in Patients With Chronic Plaque Psoriasis (PsO)
This is a two part study comparing CHS-0214 to Enbrel in patients with chronic plaque PsO who have not yet received any biologic therapy for any indication (other than insulin or hormones).
- Trial name
- NCT02134210
- Testing
- Etanercept, CHS-0214
- Where
- 100 sites in United States, Australia and 5 more
- Volunteers
- 521 people
- Sponsor
- Coherus Oncology, Inc.
Psoriasis (PsO)
Microbiome and Clinical Response to Probiotics and Methotrexate in Early Psoriasis: a Pilot Study
The goal of this clinical trial is to learn if probiotics work to improve the response of psoriatic patients to methotrexate treatment in adults.
- Trial name
- NCT07169019
- Testing
- Probiotics and methotrexate, Methotrexate
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Alexandria University
Psoriasis
Excimer Laser, Serum Markers & Psoriasis
The overall aims for this study are to determine whether UVB excimer laser treatment of psoriasis affects serum inflammatory markers, and to assess hyperpigmentation and erythema with excimer laser treatment.
- Trial name
- NCT02165657
- Testing
- Excimer laser treatment
- Where
- United States
- Sponsor
- University Hospitals Cleveland Medical Center
Psoriatic Arthritis, Ankylosing Spondylitis
Presence of IBD Specific Antibodies (ASCA, ALCA, ACCA, AMCA) in the Sera of Patients With Spondyloarthropathy
A relationship between IBD and spondyloarthropathy is well recognized. ASCA ( anti saccharomyces cerevisiae antibodies)are considered to be a serological marker for Crohn's disease and have been studied in patients with…
- Conditions
- Psoriatic Arthritis, Ankylosing Spondylitis, Undifferentiated Spondyloarthropathy
- Trial name
- NCT00517101
- Volunteers
- healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Psoriasis
A Study of Effectiveness and Safety of Tumor Necrosis Factor (TNF) Inhibitors in Patients With Moderate to Severe Psoriasis
In recent years, biologics have changed the treatment of psoriasis, giving us additional therapeutic options that are potentially less toxic to the liver, kidneys, and bone marrow and are not teratogenic.
- Trial name
- NCT01126619
- Where
- 25 sites in Turkey (Türkiye)
- Volunteers
- 103 people
- Sponsor
- Abbott
Psoriasis
Effectiveness and Safety of Topical Halobetasol Propionate in the Treatment of Patients With Psoriasis
The Psoriasis and a chronic dermatosis characterized by abnormal proliferation of cells epithelial, vessel dilation and inflammation locally, which presents erythematous-scaly lesions in various areas of the body, preferably in…
- Trial name
- halobetasol (NCT00715975)
- Testing
- halobetasol, clobetasol
- Where
- Brazil
- Volunteers
- 140 people
- Sponsor
- Azidus Brasil
Psoriasis
A Study of Persistence to Guselkumab Treatment in Participants With Moderate-to-Severe Plaque Psoriasis in Romania
This study aims to assess the proportion of participants with moderate-to-severe plaque psoriasis who continue treatment with guselkumab over a two-year period.
- Trial name
- PROGRESS-RO (NCT07582783)
- Where
- 20 sites in Romania
- Volunteers
- 200 people
- Sponsor
- Janssen Research & Development, LLC
Psoriasis
A Study of LY3471851 in Participants With Psoriasis
The main purpose of this study is to learn more about the safety of LY3471851 when given by injection just under the skin to participants with psoriasis.
- Trial name
- NCT04119557
- Testing
- LY3471851
- Where
- 24 sites in United States
- Volunteers
- 30 people
- Sponsor
- Nektar Therapeutics
Psoriasis Vulgaris
Narrowband UVB Light Therapy to Patients With Dark Skin Types Who Have 10% of Their Body Involved With Psoriasis Vulgaris.
This study offers narrowband UVB light therapy to patients with both light and dark skin types who have 10% of their body involved with psoriasis vulgaris.
- Trial name
- NCT00220025
- Testing
- Phototherapy
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Mary Sullivan-Whalen
Spondyloarthropathy
Clinical Characteristics of Importance to Outcome in Patients With Spondyloarthritis
The objective of the study is to investigate extra-articular manifestations, pain mechanisms, patient-reported outcomes, comorbidities and association between these conditions in patients with spondyloarthropathy (SpA) treated…
- Trial name
- NCT02948608
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Svendborg Hospital
Psoriatic Arthritis
Do Patients With Skin Psoriasis Have Sub-clinical Features of Active Psoriatic Arthritis on Musculoskeletal UltraSound?
Psoriatic Arthritis is an inflammatory condition that typically affects joints and soft tissues such as tendons. Poorly controlled or untreated psoriatic arthritis can lead to joint damage, disability and poor physical and mental…
- Trial name
- PsACT-US (NCT04857476)
- Testing
- Ultrasound scan
- Where
- United Kingdom
- Volunteers
- 8 people
- Sponsor
- The Royal Wolverhampton Hospitals NHS Trust
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