Clinical trials: Psoriasis Vulgaris
Psoriasis Vulgaris
PSOREAL - Managing PSOriasis in the REAL World
Multinational real-life study of current psoriasis treatment strategies, topical treatment patterns and treatment outcomes of these treatments, including the newly introduced calcipotriol/betamethasone dipropionate aerosol foam…
- Trial name
- PSOREAL (NCT02935582)
- Testing
- Enstilar® aerosol foam, Other topical
- Where
- 3 sites in Canada, Sweden and 1 more
- Volunteers
- 1,214 people
- Sponsor
- LEO Pharma
Psoriasis Vulgaris
Blue Light for Treating Psoriasis Vulgaris
The purpose of this study is to determine the efficacy and safety of a blue light device for treating Psoriasis vulgaris. The study will compare a blue light treated plaque with an untreated control plaque.
- Trial name
- NCT02004847
- Testing
- PSO-CT02
- Where
- Germany
- Volunteers
- 47 people
- Sponsor
- Philips Electronics Nederland BV
Psoriasis Vulgaris
Oral and Topical Phytocannabinoids for Psoriasis
Psoriasis is a chronic inflammatory skin disease that affects approximately 2% of the global population and is frequently associated with psychiatric comorbidities such as anxiety and depression.
- Trial name
- CBDermis (NCT07839455)
- Testing
- Oral Cannabis Extract, Topical cannabis cream
- Where
- Brazil
- Volunteers
- 37 people
- Sponsor
- Federal University of Latin American Integration
Psoriasis Vulgaris
Psoriatic Immune Response to Tildrakizumab
This study aims to assess cutaneous and blood immune cell function of patients with psoriasis before and after initiation of treatment with the IL23 blocker, tildrakizumab.
- Trial name
- NCT05390515
- Testing
- Tildrakizumab Prefilled Syringe
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of California, San Francisco
Hidradenitis Suppurativa (HS)
Efficacy and Safety Study of Adalimumab in the Treatment of Hidradenitis Suppurativa
A study to evaluate the safety and efficacy of treatment with adalimumab in adults with moderate to severe hidradenitis suppurativa (HS).
- Trial name
- PIONEER II (NCT01468233)
- Testing
- adalimumab
- Volunteers
- 326 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Psoriasis Vulgaris
Shuiniujiao Dihuang Decoction With Variation for the Treatment of Psoriasis
Psoriasis is an inflammatory skin disease with huge negative impact on the quality of life of the patients, and has an overall prevalence of 2% to 3% in the general population.
- Trial name
- NCT05815797
- Testing
- SDD formula
- Where
- Hong Kong
- Volunteers
- 58 people
- Sponsor
- Chinese University of Hong Kong
Psoriasis Vulgaris
Role of Topical Treatments in the Modulation of Skin Microbiome in Psoriatic Skin
Changes in microbiome have been reported recently in psoriasis lesions compared to healthy surround skin. Preliminary data showed that systemic treatments of psoriasis induce modification of the skin microbiome that becomes…
- Trial name
- Microbiome&Pso (NCT03584360)
- Testing
- Betamethasone-Calcipotriene Topical
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Psoriasis Vulgaris
Laser Induced Changes to Innervation and Vascularisation of Psoriatic Skin
The researchers investigate the effect of a treatment with selective photothermolysis using a 595 nm pulsed dye laser on the blood vessel density and the nerve fibre density of a psoriatic lesion.
- Trial name
- LPA-01 (NCT05079256)
- Testing
- 595 nm Pulsed dye laser (Candela V-beam perfecta)
- Where
- Netherlands
- Volunteers
- 22 people
- Sponsor
- Nick van der Beek
Psoriasis Vulgaris
Effect of Calcipotriol Plus Hydrocortisone Ointment on the Adrenal Hormone Balance and Calcium Metabolism in Patients With Psoriasis Vulgaris on the Face and Skin Folds
There are few therapies suitable for the treatment of psoriasis on the face and skin folds. As these areas are sensitive, irritation and other adverse reactions are more common than elsewhere on the body.
- Trial name
- NCT00704262
- Testing
- Calcipotriol plus hydrocortisone (LEO 80190)
- Where
- 11 sites in United States, Canada and 2 more
- Volunteers
- 33 people
- Sponsor
- LEO Pharma
Psoriasis Vulgaris
LEO 90100 Twice Weekly Maintenance Regimen for Psoriasis Vulgaris
A phase 3 trial comparing the efficacy and safety of LEO 90100 aerosol foam with the aerosol foam vehicle used twice weekly as long-term maintenance therapy in subjects with psoriasis vulgaris.
- Trial name
- NCT02899962
- Testing
- LEO 90100 aerosol foam, LEO 90100 aerosol foam vehicle
- Where
- 58 sites in United States, Canada and 4 more
- Volunteers
- 722 people
- Sponsor
- LEO Pharma
Psoriasis Vulgaris
Dose Tapering Study of Adalimumab in Psoriasis
The optimal therapeutic serum trough level (Ctrough) of adalimumab was defined between 3,5 and 7,0 µg/ml in patients with plaque type psoriasis. An adalimumab Ctrough above this therapeutic range did not add clinical response.
- Trial name
- NCT04028713
- Testing
- Venapuncture, Dried blood spot, Dose reduction
- Where
- 7 sites in Belgium
- Volunteers
- 19 people
- Sponsor
- University Hospital, Ghent
Psoriasis Vulgaris, Psoriatic Arthritis
Special Drug Use-results Survey to Evaluate Safety and Efficacy of Cosentyx in Pediatric Patients With PsV, PsA, or GPP
This was a multicenter, centrally registered observational study without a control group. This observational study was a specified drug use-results survey conducted under GPSP to collect information on safety and efficacy during…
- Conditions
- Psoriasis Vulgaris, Psoriatic Arthritis, Pustular Psoriasis
- Trial name
- NCT05215561
- Testing
- Cosentyx
- Where
- 21 sites in Japan
- Volunteers
- 36 people
- Sponsor
- Novartis Pharmaceuticals
Psoriasis Vulgaris, Psoriatic Arthritis
Impact of Decision-Framing in Psoriasis
Rationale: Shared decision-making models between clinicians and patients are critical to improving healthcare delivery and adherence to medication. One type of model, decision framing, is rarely studied in medicine.
- Conditions
- Psoriasis Vulgaris, Psoriatic Arthritis, Psoriasis
- Trial name
- NCT04136314
- Testing
- Decision-Framed Survey
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Psoriasis Vulgaris
Analysis of Non-Invasively Collected Microneedle Device Samples From Mild Plaque Psoriasis for Use in Transcriptomics Profiling
The purpose of this study is to collect skin biopsies and non-invasive microneedle device samples from participants with mild chronic plaque psoriasis vulgaris to use for transcriptomics profiling for further investigation.
- Trial name
- NCT03795402
- Testing
- Microneedle Device
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- Janssen Research & Development, LLC
Psoriasis Vulgaris
An International, Multi-centre, Prospective, Non-controlled, Open, Single-group, 8-week Trial in Adolescent Subjects
An international, multi-centre, prospective, non-controlled, open, single-group, 8-week trial in adolescent subjects (aged 12 to 16 years, 11 months) with scalp and body psoriasis.
- Trial name
- NCT02038569
- Testing
- LEO 80185 gel
- Where
- 35 sites in United States, Canada and 5 more
- Volunteers
- 125 people
- Sponsor
- LEO Pharma
Psoriasis
Luma Light System Proof of Concept Study in Subjects With Mild to Moderate Psoriasis
This is a proof of concept, investigator blinded study to evaluate the efficacy and safety of a novel combination of a home narrow band ultraviolet B (NBUVB) lamp with an occlusive dressing in adult subjects with mild to moderate…
- Trial name
- NCT02447068
- Testing
- Luma Light System, Luma Light, Occlusive Dressing
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Illumicure Inc
Psoriasis Vulgaris
A Phase 3 Study of Efficacy and Safety of AK101 in Subjects With Psoriasis
This is a randomized, double-blind, placebo-controlled, multicentered phase III clinical study to evaluate the efficacy and safety of AK101 in the treatment of subjects with moderate-to-severe plaque psoriasis.
- Trial name
- NCT05120297
- Testing
- AK101
- Where
- 52 sites in China
- Volunteers
- 452 people
- Sponsor
- Akeso
Allergic Cutaneous Vasculitis, Urticaria
Clinical Utility Of Genetic Screening For HLA-B*1301, On Susceptibility To Dapsone Hypersensitivity Syndrome
This Study is to evaluate the utility of prospective HLA-B*1301 screening on the incidence of dapsone hypersensitivity syndrome (DHS) in 3130 previously Dapsone(DDS)-naive patients.
- Conditions
- Allergic Cutaneous Vasculitis, Urticaria, Psoriasis, Acne
- Trial name
- NCT02550080
- Testing
- Dapsone, HLA-B*1301
- Where
- China
- Volunteers
- 3,130 people
- Sponsor
- Shandong Provincial Institute of Dermatology and Venereology
Psoriasis Vulgaris
A Psoriasis Plaque Test Comparing Eight Different Formulations of Vitamin D Analogues for the Treatment of Psoriasis
The purpose of this trial is to compare the anti-psoriatic effect of eight different formulations of vitamin D analogues using a psoriasis plaque test design
- Trial name
- NCT01105286
- Testing
- Six different calcipotriol ointment formulations, and two currently marketed topical vitamin D analogues
- Where
- France
- Volunteers
- 24 people
- Sponsor
- LEO Pharma
Psoriasis
BAY1003803 Formulation Comparison in Open Psoriasis Plaque Test
To explore the efficacy and safety of four BAY1003803 formulations by means of a within subject comparison in an open Psoriasis Plaque Test
- Trial name
- NCT02940002
- Testing
- BAY1003803, Clobetasol propionate, Betamethasone/calcipotriene
- Where
- 3 sites in Germany
- Volunteers
- 23 people
- Sponsor
- Bayer