Clinical trials: Psychiatric Disorder
Cannabis, THC
Modulation of THC Effects by CBD: a Dose-ranging Study
The purposes of this study are 1) to determine if CBD modulates THC-induced acute psychoactive effects at different CBD:THC ratios, compared with the control product (0:20, 20:20, 40:20, 80:20, 120:20) and 2) to determine if…
- Trial name
- SPECTRE (NCT06099379)
- Testing
- ∆9-tetrahydrocannabinol
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Smoking
Cue Reactivity in Virtual Reality: The Role of Context
The objectives of this proposal are to examine the role of context in a virtual reality (VR) environment and to explore the extent to which cues (i.e., contextual cues or explicit smoking cues) influence craving and physiological…
- Trial name
- NCT00862927
- Testing
- Breath Sample, Saliva Sample, Questionnaire
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Covid19, Stress
A Study on Prevalence, Protection and Recovery From COVID-19 in Seasoned Yoga Practitioners in Comparison to Age and Gender Matched Controls
The study is a randomized controlled trail with an observational arm and aims at collecting information on the prevalence of COVID 19 infection in seasoned yoga practitioners by comparing it with the prevalence of COVID-19…
- Conditions
- Covid19, Stress, Anxiety Depression
- Trial name
- NCT04498442
- Testing
- Simha Kriya, Reading a Book
- Where
- United States
- Volunteers
- 8,519 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Cognitive Dysfunction, Alzheimer Disease
ALA-enriched Nutrition for Prevention of Cognitive Decline in APOE4 Older Adults
This randomized, double-blind, placebo-controlled pilot trial will evaluate the effects of alpha-linolenic acid (ALA) supplementation on cognitive function, blood-brain barrier integrity, and brain vascular health in older adults…
- Conditions
- Cognitive Dysfunction, Alzheimer Disease, Blood-Brain Barrier, Apolipoprotein E, Deficiency or Defect of
- Trial name
- NCT07392723
- Testing
- Alpha-Linolenic Acid (2.6 g/day)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Michal Schnaider Beeri, Ph.D.
Artificial Intelligence Technology, Cognitive Decline
Preliminary Research Using Artificial Intelligence Technology to Identify Differences in Facial Expressions Between Healthy People, Patients With Cognitive Decline, and Patients With Dementia
Through artificial intelligence technology, we have conducted a preliminary study aimed at identifying differences in facial expressions among healthy individuals, patients with cognitive decline, and dementia patients.
- Conditions
- Artificial Intelligence Technology, Cognitive Decline, Dementia, Identify
- Trial name
- NCT06513403
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Attention Deficit Disorder With Hyperactivity (ADHD), Sustained Attention
The Effects of Lemon Essential Oil Inhalation on Attention in Children With Attention Deficit Hyperactivity Disorder (ADHD)
This randomized, placebo-controlled clinical trial aims to evaluate the acute effects of lemon essential oil inhalation on sustained attention and visual memory in children diagnosed with Attention-Deficit/Hyperactivity Disorder…
- Conditions
- Attention Deficit Disorder With Hyperactivity (ADHD), Sustained Attention, Aromatherapy, Essential Oil
- Trial name
- NCT07586761
- Testing
- Lemon Essential Oil Inhalation
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Opioid Overdose
Preventing Opioid Overdose Mortality in the United States
This study aims to conduct a randomized controlled trial of 105 syringe services programs (SSPs) throughout the United States to understand the effectiveness of a multifaceted, facilitation-based strategy at advancing naloxone…
- Trial name
- NCT03924505
- Testing
- Organize and Mobilize for Implementation Effectiveness, Dissemination
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- RTI International
Mild Cognitive Impairment (MCI), Cognition
LpD3.5 Intervention Study in Older Adults- LISA-I Trial
This randomized placebo-controlled clinical study, called the LpD3.5 Intervention Study in Older Adults (LISA), aims to evaluate whether a heat-inactivated postbiotic of human origin (LpD3.5) can serve as a non-pharmacological…
- Conditions
- Mild Cognitive Impairment (MCI), Cognition, Brain Aging, Microbiome Dysbiosis
- Trial name
- Postbiotics (NCT07794956)
- Testing
- LpD3.5
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Cognition Disorders
Longitudinal Evaluation of Amyloid Risk and Neurodegeneration - the LEARN Study
The LEARN study a multicenter, observational study will that will evaluate the rate of cognitive change in approximately 500 clinically normal older individuals who "screen-fail" for the A4 trial on the basis of their screening…
- Trial name
- LEARN (NCT02488720)
- Where
- 40 sites in United States
- Volunteers
- 538 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Attention Deficit Disorder With Hyperactivity, Dental Caries
Oral Status and Prevalence of Dental Trauma in Children Treated With Ritalin Due to Attention-Deficit Hyperactivity Disorder (ADHD)
To evaluate the dental status of children using ritalin and suffering from ADHA in comparison to healthy children.
- Conditions
- Attention Deficit Disorder With Hyperactivity, Dental Caries, Dental Occlusion, Traumatic
- Trial name
- NCT00328224
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Sleep Deprivation
Protective Effect of Statin on Sleep Deprivation
This study aimed to investigate the effect of 48-h sleep deprivation on heart rate variability (HRV) in young healthy people and the protective effect of statin on arrhythmia and HRV.
- Trial name
- NCT02496962
- Testing
- Atorvastatin
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Shi Yang
Major Depressive Disorder
A Neuroimaging Investigation of Brain Activity in Major Depressive Disorder and Bipolar Disorder
This study employs functional magnetic resonance imaging to compare brain activation patterns during a depressive episode in patients diagnosed with bipolar disorder, major depressive disorder, and a group of healthy control…
- Trial name
- NCT00188942
- Testing
- Fluoxetine+Olanzapine, Olanzapine, Functional Magnetic Resonance Imaging
- Where
- 2 sites in Canada
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Parkinson Disease, Alzheimer Disease
Autoimmune Features of Neurodegenerative Disorders
This study is being conducted to better understand the role of inflammation in Parkinson's disease (PD) and Alzheimer's disease (AD).
- Conditions
- Parkinson Disease, Alzheimer Disease, Mild Cognitive Impairment
- Trial name
- NCT04239079
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Columbia University
MAJOR DEPRESSIVE DISORDER
Influenza Challenge in Mood Disorders
The aim of this project is to evaluate the efficacy of the influenza vaccine in individuals with major depressive disorder (MDD) as well as to elucidate the nature of the immunological abnormalities in MDD using a…
- Trial name
- NCT02415166
- Testing
- INFLUENZA VACCINE
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
ADHD, Attention Deficit Hyperactivity Disorder
Healthy Lifestyle in Adults With Attention Deficit Hyperactivity Disorder
The purpose of this study is to understand the relationship between ADHD and the overall health of someone with ADHD. People who have ADHD have trouble paying attention, concentrating, organizing, and planning.
- Trial name
- NCT00879320
- Where
- United States
- Volunteers
- 253 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Mental Health Disorder, Oral Health-Related Quality of Life
Impact of Maternal Mental Health on the Oral Health Status and Oral Health-related Quality of Life of Their Children
Dental caries is a complex multifactorial disease that is strongly related to and influenced by the children's dietary habits, sugar intake, salivary flow, salivary fluoride level, and preventive behaviors.
- Trial name
- NCT05753423
- Testing
- Interview-based questionnaires & Clinical examination
- Where
- Egypt
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Dyspareunia, Endometriosis
Dyspareunia in Women With Endometriosis: Impact of Surgery on Sexual Health
Endometriosis is a disease that affects different areas of individual functioning, including the area of sexual life. Women with endometriosis have an impairment of desire and sexual arousal, orgasmic capacity reducted because of…
- Trial name
- NCT02484196
- Testing
- Questionnaires
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
Aging and Exercise Impacts on Glymphatic Function
Aging and Exercise Impacts on Glymphatic Function
This is a prospective, interventional, non-blinded, single center research project that will recruit cognitively unimpaired subjects in the 25-55 year old and 55-75 year old range.
- Trial name
- NCT07775196
- Testing
- Acute Aerobic exercise
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Intellectual Disability
Development and Validation of the Observatory Battery of Common Eye Disorders for Adults With Intellectual Disability
Background: Around 15% of the global population has some form of disability. Rights to obtain proper health care is an emphasis in the United Nationals Convention on the Right of People with Disability.
- Trial name
- NCT06737627
- Testing
- no intervention
- Where
- 2 sites in Taiwan
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Major Depressive Disorder
Augmentation of the Antidepressant Action of Sertraline With Triiodothyronine (T3)and Reboxetine: Clinical Efficacy, Adverse Effects and Predictors of Response.
In this project we aim to further refine indications for the use of the thyroid hormone - T3 for patients suffering from depression.
- Trial name
- NCT00421369
- Testing
- sertraline, triiodothyronine (T3), reboxetine
- Where
- Israel
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
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