Clinical trials: Psychiatric Disorder
Attention Deficit Hyperactivity Disorder
Brain Dopamine Function in Adults With ADHD
The purpose of the study is to investigate the functional state of dopamine cells and the dopamine transporter in ADHD subjects and controls to assess the effects of chronic methylphenidate treatment on dopamine cell function and…
- Trial name
- Brookhaven (NCT00580814)
- Testing
- Experimental: methylphenidate treatment
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
The Role of the LC-NA System in Sleep Regulation
The Role of the LC-NA System in Experimental Sleep Fragmentation
Sleep-wake regulation affects every person's life, yet the molecular mechanisms underlying these processes remain poorly understood.
- Trial name
- DMTN_FragSleep (NCT07167316)
- Testing
- DMTN, Auditory Stimulation, Placbo
- Where
- Switzerland
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hans-Peter Landolt
Brain DHA Delivery and Alzheimer's Disease Risk
DHA Brain Delivery Trial
Carrying the APOE ɛ4 allele is the strongest genetic risk factor for developing Alzheimer's disease. The goal of this project is to identify whether carrying the APOE ɛ4 allele is associated with reduced delivery of DHA to the…
- Trial name
- PreventE4 (NCT03613844)
- Testing
- DHA
- Where
- United States
- Volunteers
- 365 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Antisocial Behavior, Aggression
The Effect of Repeated Prefrontal Cortex Stimulation on Antisocial and Aggressive Behavior
This study investigates the relationship between prefrontal cortex activity and antisocial and aggressive behavior, and risk factors for such behavior.
- Trial name
- NCT02674516
- Testing
- Transcranial direct current stimulation
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Emergence Agitation
Dexmedetomidine and Propofol in the Treatment of Emergence Agitation
1. This clinical research aims to compare the effects of dexmedetomidine and propofol on the treatment of emergence agitation in adult patients after general anesthesia. 2.
- Trial name
- NCT04142840
- Testing
- Dexmedetomidine, Propofol
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Sleep Disturbance, Shoulder Arthritis
Multimodal Sleep Pathway for Shoulder Arthroplasty
The purpose of the study is to investigate the efficacy of sleep medicine in the recovery of orthopaedic shoulder arthroplasty patients.
- Conditions
- Sleep Disturbance, Shoulder Arthritis, Arthroplasty Complications, Perioperative/Postoperative Complications
- Trial name
- NCT03269760
- Testing
- Zolpidem
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Autism Spectrum Disorder
Improving ToM in Children With ASD Through VPT Training: Behavioral and fNIRS Study
This study aims to employ a longitudinal tracking research to investigate the effects of a visual perspective taking intervention on the development of theory of mind in children with autism.
- Trial name
- NCT06196060
- Testing
- Visual perspective taking training, Block building training, Thought-bubble training
- Where
- 3 sites in China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nanjing Normal University
Neurological Disease, Motor Disorders
Technological Devices and Home Automation System in Neurological Rehabilitation
The use of home automation system may be useful in rehabilitation to collect data about the environment and the amount of therapy.
- Trial name
- SMART (NCT06270420)
- Testing
- Technological Motor Rehabilitation
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Dementia, Memory Disorders
Preventing Cognitive Decline With Alternative Therapies
Preventing dementia is an important goal for our aging population. This proposal is an initial 42 months study of the effect of standardized ginkgo biloba extract (GBE) on preventing or delaying cognitive decline in people age 85…
- Trial name
- NCT00010920
- Testing
- Ginkgo Biloba Extract
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Sleep Initiation and Maintenance Disorders, Depression
Night in Japan Home Sleep Monitoring Study
The investigators hypothesized that depression is associated with home sleep EEG, subjective sleepiness and insomnia symptoms. To test this, the investigators plan to perform sleep examination with single channel EEG, in…
- Trial name
- NinJaSleep (NCT03276585)
- Where
- Japan
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Shiga University
Healthy Volunteers
Effect of Metabolic State on Anxiety in Human Subjects
In this study, we would like to explore the hypothesis that changes in metabolic state, induced by altering hormone levels and patterns of neural activity, affect the experience of anxiety in humans.
- Trial name
- NCT01322243
- Testing
- Dietary manipulation
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Rockefeller University
Problem Behavior
Steps to Effective Problem Solving in Group Homes
Aggressive/challenging behaviors in individuals with intellectual disability are a major public health concern for them, their families, their service programs and staff, and their communities.
- Trial name
- STEPS (NCT02855008)
- Testing
- STEPS, Food for Life
- Where
- United States
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Pathological Gambling
Community Reinforcement Approach and Family Training (CRAFT) for Problem Gambling
Nova Scotia is experiencing a proliferation of gambling opportunities and their related gambling problems. The 2003 Nova Scotia Prevalence Study (2004) found that approximately 50,000 adult Nova Scotians are at some risk for…
- Trial name
- NCT01340274
- Testing
- CRAFT treatment, Treatment as Usual
- Where
- 3 sites in Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Colchester East Hants Health Authority
Bipolar Disorder
Mental Time Travel and Identity in Bipolar Disorder Patients
Self-defining memories (SDMs) are memories that are still important today to understand who the investigators are and participate to the maintain of personal identity.
- Trial name
- NCT02793518
- Testing
- psychological tests
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Sleep Disturbance, Sleep Patterns
Probiotics on Sleep Among Adults Study
The aim of this study is to determine the impact of a probiotic formulation on subjective sleep patterns. It is hypothesized that participants given the probiotics will improve their sleep patterns compared to participants…
- Trial name
- NCT04767997
- Testing
- Probiotic formulation
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Lallemand Health Solutions
Depressive Disorder, Major
Dialogue to Empower Traditional and Faith Healers to Deliver mhGAP-IG Adapted Psychosocial Interventions in Kenya
The project aimed to create a dialogue between the informal sector (traditional and faith healers) and the formal sector (trained health care workers) in order to increase synergy and communication between the two systems, by…
- Trial name
- Dialogue (NCT03165513)
- Testing
- mhGAP-IG
- Volunteers
- 4,081 people, healthy volunteers welcome
- Sponsor
- Africa Institute of Mental and Brain Health (AFRIMEB)
Mood Disorder, Anxiety Disorder
Validation of an Automated Online Language Interpreting Tool - Phase Two.
There is a pressing national need to provide higher-quality, more effectively accessible language interpretation services to improve the health outcomes of Americans who have limited English proficiency (LEP).
- Conditions
- Mood Disorder, Anxiety Disorder, Substance Use Disorder, Chronic Medical Condition
- Trial name
- NCT03538860
- Testing
- Active comparator: Human interpreter, Intervention: Asynchronous Telepsychiatry
- Where
- United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Alzheimer Disease, Dementia
HEARS-NPS: Addressing Hearing Loss as a Common Unmet Contributor of Neuropsychiatric Symptoms
This randomized controlled trial study aims to evaluate a revised hearing care intervention for older adults with Alzheimer's Disease and Related Dementias (ADRD).
- Conditions
- Alzheimer Disease, Dementia, Hearing Loss, Cognitive Impairment
- Trial name
- HEARS-NPS (NCT06930560)
- Testing
- HEARS-NPS device, HEARS-NPS program
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Arterial Stiffness, White Matter Lesions
Effect of Equol Supplementation on Arterial Stiffness and Cognition in Healthy Volunteers
The ACE Trial, funded by the National Institute on Ageing/National Institutes of Health (NIH), is a multicenter clinical trial. The ACE Trial will determine if taking the dietary supplement Equol could slow the progression of…
- Conditions
- Arterial Stiffness, White Matter Lesions, Cognitive Decline
- Trial name
- ACE (NCT05741060)
- Testing
- S-equol
- Where
- 3 sites in United States
- Volunteers
- 369 people, healthy volunteers welcome
- Sponsor
- Akira Sekikawa
Erectile Dysfunction, Coronary Artery Disease
Erectile and Ejaculatory Function Following Coronary Revascularization
This observational, cross-sectional study aims to compare erectile and ejaculatory function between men with a history of coronary revascularization and men without known coronary artery disease.
- Conditions
- Erectile Dysfunction, Coronary Artery Disease, Ejaculation Disorders
- Trial name
- NCT07878260
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
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