Clinical trials: Psychiatric Disorder
Healthy Subjects, Restless Legs Syndrome
Infra-slow Oscillations During Sleep
In this study the investigators plan to systematically characterise infra-slow EEG oscillations during sleep, explore their relationship to the microstructure of sleep, and investigate its role in the physiology and…
- Conditions
- Healthy Subjects, Restless Legs Syndrome, Periodic Limb Movements During Sleep
- Trial name
- SleepD-ISO (NCT02532608)
- Testing
- Acute sleep deprivation
- Where
- Switzerland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Stephany Fulda
Opioid Use Disorder, Opioid Dependence
Measuring Acute Drug Demand in Humans
This research is being done to evaluate whether suvorexant may reduce the use of, subjective liking, and demand for various drugs.
- Trial name
- NCT05829655
- Testing
- Drug A (Blinded Drug), Drug B (Blinded Drug), Drug C (Blinded Drug)
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Depressive Symptoms, Mental Health Wellness 1
Mindfulness and Intercare Based Intervention for Medicine Students (MIIM)
The effects of Coronavirus Disease (COVID-19) pandemic on health, economy and social network has an impact on mental health, specially students.
- Conditions
- Depressive Symptoms, Mental Health Wellness 1, Anxiety
- Trial name
- MIIM (NCT05011955)
- Testing
- Mindfulness, compassion and intercare based Intervention, Psychoeducational based intervention, General curricular intervention
- Where
- Chile
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University Diego Portales
Schizophrenia, Major Depressive Disorder
Identification of Multi-modal Bio-markers for Early Diagnosis and Treatment Prediction in Schizophrenia Individuals
This study aims to screen and validate multi-scale bio-markers for early diagnosis and medication monitoring for early schizophrenia, including the genetic, neurobiochemistry, neuroimaging and eletrophysiological measures.
- Conditions
- Schizophrenia, Major Depressive Disorder, Anxiety Disorders
- Trial name
- NCT03790085
- Testing
- Risperidone, Olanzapine, Aripiprazole
- Where
- China
- Volunteers
- 2,700 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University General Hospital
Generalized Anxiety Disorder, Seroquel XR
Generalized Anxiety and Seroquel
The 12 week clinical trial of Seroquel in Generalized Anxiety Disorder (GAD) patients will be combined with fMRI experiments.
- Trial name
- GAD (NCT01066143)
- Testing
- Seroquel XR
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Personal Satisfaction
Effects on Mindfulness Meditation on Patient's Satisfaction During Urodynamic Study
The purpose of this investigator-initiated study is to evaluate if mindfulness-based stress reduction (MBSR) will improve satisfaction and reduce anxiety during a urodynamic study (UDS).
- Trial name
- NCT04446143
- Testing
- Mindfulness meditation
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Postoperative Delirium
EEG-Guided Analgesic Titration During General Anesthesia to Improve Early Neurocognitive Recovery in Older Patients
The investigators intend to recruit 600 participants to see if alpha power during anesthesia is influenced by analgesic medication and associated with a reduction of delirium following surgery.
- Trial name
- ALPHA-DEX (NCT04443517)
- Testing
- Alpha Optimization, Emergence from anesthesia with Dexmedetomidine
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Columbia University
Asthma, Respiratory Tract Infections
VItamin D in pregnanCy for prevenTion Of eaRlY Childhood Asthma
The overall aim of the study is to develop a nutritional preventive vitamin D supplementation strategy in pregnancy for early childhood asthma/persistent wheeze during the first three years of life as we hypothesize that…
- Conditions
- Asthma, Respiratory Tract Infections, Gastrointestinal Infection, Croup
- Trial name
- VICTORY (NCT06570889)
- Testing
- Cholecalciferol D3, Olive oil
- Where
- Denmark
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Professor Klaus Bønnelykke
Sleep Initiation and Maintenance Disorders
Operational Trial of Dayzz App
Sleep deficiency is a hidden cost of our 24-7 society, with 70% of Americans admitting that they routinely obtain insufficient sleep, 30% of US workers report sleeping less than 6 hours per night, and it is estimated that 50-70…
- Trial name
- NCT04224285
- Testing
- Dayzz app
- Where
- United States
- Volunteers
- 1,355 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Dementia, Alzheimer Disease
Multidisciplinary Expert System for the Assessment & Management of Complex Brain Disorders
The Multidisciplinary Expert System for the Assessment \& Management of Complex Brain Disorders (MES-CoBraD) is an interdisciplinary project combining Real-World Data (RWD) from multiple clinical and consumer sources through…
- Conditions
- Dementia, Alzheimer Disease, Epilepsy, Sleep Disorder
- Trial name
- MES-CoBraD (NCT05171725)
- Testing
- EEG,PSG, biosample collection (blood and CSF), neuropsychological testing
- Where
- 4 sites in Greece, Israel and 2 more
- Volunteers
- 635 people, healthy volunteers welcome
- Sponsor
- Neurological Institute of Athens
Attention Deficit Hyperactivity Disorder
Influence of Education on Acceptance of Treatment for Attention Deficit Hyperactivity Disorder (ADHD) Among Women
The goal of this research study is to measure what percentage of women who suspect they have symptoms of ADHD will go on to be diagnosed with ADHD using accepted practice standards.
- Trial name
- NCT01272726
- Testing
- Education
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Avera McKennan Hospital & University Health Center
Substance Use
Health and Resilience Projects: Foundations
The Health and Resilience Project (HARP): Foundations is investigating the efficacy of the Strong African American Families (SAAF) intervention in promoting the health and well being of African American adolescents.
- Trial name
- HARP-F (NCT05253235)
- Testing
- SAAF, Receipt of parenting book
- Where
- United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Smoking Cessation, Tobacco Dependence
Smoking-cessation: A Spanish-Language Clinical Trial
The purpose of this study is to develop and test a series of culturally relevant and appropriate booklets in Spanish, designed to assist Hispanic smokers in quitting smoking and remaining smoke-free.
- Trial name
- NCT02611076
- Testing
- Stop Smoking for Good Intervention in Spanish (SS-SP), Usual care (UC)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Schizophrenia
Culturally Based Family Therapy for Improving Treatment Outcome for People With Schizophrenia
This study will evaluate the effectiveness of a culturally based family therapy intervention in improving treatment outcome in people with schizophrenia.
- Trial name
- NCT00356317
- Testing
- Culturally informed therapy for schizophrenia (CIT-S), Psychoeducation treatment as usual
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Miami
Acute Stress Disorder, Anxiety
Safety & Efficacy of Intranasal Dexmedetomidine, Fentanyl & Midazolam in the Pediatric Emergency Room
The hypothesis is that intranasal dexmedetomidine will provide significantly more effective analgesia and anxiolysis for subjects undergoing a simple laceration repair when compared to either intranasal fentanyl or intranasal…
- Conditions
- Acute Stress Disorder, Anxiety, Pain
- Trial name
- NCT05057689
- Testing
- Intranasal Dexmedetomidine (4 mcg/kg), Intranasal Fentanyl (2 mcg/kg), Intranasal Midazolam (5 mg/kg)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Insomnia, Insomnia Disorder
Rumination-Tailored Guided Internet-Based CBT-I for University Students
The goal of this clinical trial is to evaluate whether adding rumination-tailored, rule-based personalized feedback to guided internet-based cognitive behavioral therapy for insomnia (iCBT-I) improves treatment outcomes in…
- Trial name
- RUM-CBTI (NCT07623889)
- Testing
- Guided Internet-Based Cognitive Behavioral Therapy for Insomnia (iCBT-I), Rumination-Tailored Rule-Based Personalized Feedback
- Where
- Iran
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Post-operative Pain, Acute, Cesarean Section
Management of Postoperative Pain After Cesarean Delivery Using Bridge Auricular Percutaneous Nerve Field Stimulator
Post-cesarean section (CS) pain is commonly treated with acetaminophen, ibuprofen, and opioid medications as needed following delivery.
- Conditions
- Post-operative Pain, Acute, Cesarean Section, Opioid Use Disorder, Opioids; Harmful Use
- Trial name
- NCT06434714
- Testing
- Auricular percutaneous nerve field stimulator
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Inova Health Care Services
Schizophrenia
The Gut Metagenome Research of Schizophrenia
Research already found that patients with autistic spectrum disorders lack of Prevotella intestinal type, then schizophrenia patients may also show the specific intestinal type, so investigators want to detect the gut metagenome…
- Trial name
- NCT02708316
- Testing
- sequencing faecal metagenome
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Sleep Disorder (Disorder)
The Correlation Between Sleep Quality and Sleep Aid Use and Dietary Patterns
In this study, medical staff in emergency and critical care departments were investigated. It was assumed that the use of sleep aids and dietary patterns affected their sleep quality.
- Trial name
- NCT07019948
- Volunteers
- 378 people, healthy volunteers welcome
- Sponsor
- Wei XIA, PhD
Substance Use Disorders, Parenting
PURPOSE: A Social Media Intervention for Parent Support
The purpose of this study is to develop and test a social media-based (Facebook) intervention that provides support and skills to parents with adolescent children in treatment for substance abuse.
- Trial name
- NCT02629068
- Testing
- PURPOSE
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
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