Clinical trials: Psychiatric Disorder
Sleep Deprivation, Healthy Volunteers
Effects of Sleep Deprivation on Diaphragm Command During an Inspiratory Endurance Trial in Healthy Volunteers.
The purpose of this study is to assess the impact of sleep deprivation on subjective inspiratory endurance in healthy subjects.
- Conditions
- Sleep Deprivation, Healthy Volunteers, Diaphragm
- Trial name
- NoSleepDiaph (NCT02725190)
- Testing
- Sleepless night, Normal sleep night
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Anxiety
Feasibility and Preliminary Outcomes of the Brave Elephant Program: A Single-Arm Pretest-Posttest Study
Anxiety disorders are highly prevalent in childhood and have increased following the COVID-19 pandemic. Behavioral inhibition in early childhood is a well-established risk factor for later anxiety.
- Trial name
- Brave_Elephant (NCT07567820)
- Testing
- Brave Elephant Program
- Where
- Portugal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ISPA - Instituto Universitario de Ciencias Psicologicas, Sociais e da Vida
Schizophrenia, Normal Population
Perception Processing in Schizophrenia Patients and Normal Population
The present study aimed to examine face and object perception processes in schizophrenic patients. Schizophrenia is associated with deficits in visual processing that represent a key feature in the disorder.
- Trial name
- NCT01298349
- Where
- Israel
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Bipolar Disorder
Effects of Cannabis on Cognition and Endocannabinoid Levels in Bipolar Disorder Patients and Healthy Volunteers
Cannabis use is associated with younger age at onset of bipolar disorder, poor outcome, and more frequent manic episodes, but the effects of cannabis on cognition are less clear.
- Trial name
- NCT04231643
- Testing
- Dronabinol, Epidiolex
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Aromatherapy, Music Therapy
The Effects of Music Therapy and Aromatherapy Interventions on Pulse Rate, Blood Pressure, Anxiety, and Self-Esteem
Appropriate intervention methods should be investigated to reduce stress and fatigue of students in psychomotor skills. The aim of this study is to reveal the effects of music therapy and aromatherapy interventions on pulse…
- Trial name
- NCT06837740
- Testing
- Aromatherapy group, Aromatherapy with music therapy group
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Mardin Artuklu University
Mental Health Issue, Externalizing Behavior Problems
3D-Transition: Challenges and Resources of Children and Their Families During the Transition From Preschool to School
The 3D-Transition study is a follow-up of the 3D Cohort pregnancy study (NCT03113331, which covered from the 1st trimester of pregnancy to age 2 years) as the children transition into kindergarten and first grade.
- Conditions
- Mental Health Issue, Externalizing Behavior Problems, Internalizing Behavior Problems, Cognitive Development
- Trial name
- NCT04873518
- Where
- 3 sites in Canada
- Volunteers
- 939 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Early Psychosis
PSYCHE Cognitive Remediation & Social Recovery Study
This study is a pilot feasibility study embedded in the Early Intervention in Psychosis (EIP) services in Ireland. It explores the feasibility and acceptability of a combined cognitive remediation training and social recovery…
- Trial name
- NCT06032182
- Testing
- CRESTR Intervention, CRESTR Control
- Where
- 5 sites in Ireland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National University of Ireland, Galway, Ireland
Obsessive-Compulsive Disorder
Priming in Repetitive Transcranial Magnetic Stimulation in the Treatment of Obsessive Compulsive Disorder
Obsessive Compulsive Disorder results in high social impact, affecting quality of life and tending to a chronic course. A considerable proportion of patients, up tp 60%, remain with symptoms even thought treatment is…
- Trial name
- NCT06049706
- Testing
- Active Priming
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Suellen Andrade
Mild Cognitive Impairment, Dementia, Mild
Driving Evaluation and Fitness for Persons With Cognitive Impairments
Driving is an important activity for older adults because it frequently relates to personal independence and wellbeing. This study compared the driving behaviors of older drivers with normal cognition and with MCI in unfamiliar…
- Conditions
- Mild Cognitive Impairment, Dementia, Mild, Driving Impaired, Drive
- Trial name
- NCT04648735
- Testing
- driving evaluation and practice
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- National Cheng Kung University
Schizophrenia and Related Disorders, Schizophrenia
Overcoming Psychomotor Slowing in Psychosis (OCoPS-P)
Psychomotor slowing is a major problem in psychosis. Aberrant function of the cerebral motor system is linked to psychomotor slowing in patients, particularly resting state hyperactivity in premotor cortices.
- Conditions
- Schizophrenia and Related Disorders, Schizophrenia, Schizoaffective Disorder, Brief Psychotic Disorder
- Trial name
- OCoPS-P (NCT03921450)
- Testing
- 1 Hz rTMS, iTBS
- Where
- Switzerland
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of Bern
Autism Spectrum Disorder
Neuro Strengths-Based Approach to Autism
The Neuro-Strength-Based Approach to Autism (NSBAA) attempts to translate what research has discovered about the autistic brain into terms that autistics, and those involved with autistics, can understand.
- Trial name
- NSBAA (NCT05499910)
- Testing
- NSBAA
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Baio Enterprises
Anxiety
Disentangling Anxiety Sensitivity and Anxiety-induced Physiological Stress Response
The proposed study aims to investigate experimentally anxiety sensitivity and physiologic sensations associated with anxiety using a paradigm combining hydrocortisone, caffeine, and a set of social stress challenges.
- Trial name
- NCT02372110
- Testing
- HPA, ANS stimulation
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Anxiety
Sleep, Dreaming, and Virtual Reality for Mental Health
People spend approximately one-third of their lives asleep, yet sleep is often underused as an opportunity to support psychological well-being.
- Trial name
- NCT07408206
- Testing
- Dream Yoga Inspired Intervention, Sleep Health Enhancement Program (SHEP)
- Where
- 2 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Postoperative Cognitive Dysfunction, Delirium
Cohort Study to Investigate the Association Between Changes in Brain Volume and Postoperative Cognitive Dysfunction
Despite an ongoing controversy in the scientific literature, the link between anesthesia and dementia and/or cerebral atrophy remains unclear.
- Conditions
- Postoperative Cognitive Dysfunction, Delirium, Dementia
- Trial name
- POCD-MRI (NCT02045004)
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nicolai Goettel
Anxiety Disorders
Pegasys VR: Integrating Virtual Humans in the Treatment of Child Social Anxiety
Among children, social anxiety is a common, severe and chronic disorder. Social Effectiveness Therapy for Children (SET-C) is an empirically supported treatment with significant potential to impact the lives of children with this…
- Trial name
- NCT02816684
- Testing
- Pegasys-VR, Social Effectiveness Therapy for Children
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Post-Traumatic Stress Disorder
Posttraumatic Symptoms Among Toddlers and Their Parents Following Exposure to Terrorism
The project utilize experience and knowledge gained from previous early childhood projects in NYC post 9/11 and Sderot. The overall goals are: 1.
- Trial name
- NCT00447538
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Herzog Hospital
Bipolar Disorder, Unipolar Disorder
A Comprehensive Assessment and Follow up Descriptive Study on Bipolar Disorder
The purpose of this study was to investigate the reliability and validity of the bipolar index (BPX) to diagnosis bipolar disorder, and to verify the stability of it in identifying bipolar disorder; the secondary purpose was to…
- Trial name
- CAFE-BD (NCT02015143)
- Where
- China
- Volunteers
- 970 people, healthy volunteers welcome
- Sponsor
- Peking University
Major Depressive Disorder, Primary Hypersomnia
Neurophysiologic Correlates of Hypersomnia
The goal of this project is to examine the neurophysiology of hypersomnia during sleep and wakefulness, to identify biomarkers for excessive sleepiness in neuropsychiatric disorders, and pilot acoustical slow wave induction…
- Conditions
- Major Depressive Disorder, Primary Hypersomnia, Bipolar Disorder, Narcolepsy
- Trial name
- NCT01719315
- Testing
- Acoustical slow wave induction
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Alcohol Use Disorder, Alcohol Withdrawal
Does a Ketogenic Dietary Supplement Reduce Alcohol Withdrawal Symptoms in Humans?
A ketogenic diet (KD) is high in fat and low in carbohydrates and induces ketosis. KD is an approved non-pharmacological therapy for drug-resistant child epilepsy.
- Conditions
- Alcohol Use Disorder, Alcohol Withdrawal, Ketosis
- Trial name
- KME (NCT03878225)
- Testing
- H.V.M.N. Ketone Ester
- Where
- 2 sites in Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Anders Fink-Jensen, MD, DMSci
Sleep Problems, Behavioural Insomnia of Childhood
The ABCs of SLEEPING: Effectiveness Study
This trial will examine the effectiveness of a mobile applicable intervention called the "ABCs of SLEEPING". This intervention provides parents with prioritized/customized sleep recommendations and a sleep report based on their…
- Trial name
- NCT05072548
- Testing
- The ABCs of SLEEPING
- Where
- Canada
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
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