Clinical trials: Psychiatric Disorder
Cannabis
Laboratory Smoking of Marijuana "Blunts"
This is a double-blind within-subjects clinical laboratory study comparing the product appeal and abuse liability-related subjective effects of different flavored cigar wrappers for marijuana blunts.
- Trial name
- NCT03546790
- Testing
- Marijuana
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Battelle Memorial Institute
Nicotine Dependence
Impact of Alternative Nicotine-Delivery Products on Combustible Cigarette Use
The goal of this research is to understand the potential impact of two new FDA strategies to ensure the availability of safer Alternative Nicotine Delivery Systems (ANDS) and to reduce the nicotine content in combustible…
- Trial name
- NCT04084210
- Testing
- Juul Electronic cigarette, Very Low Nicotine Cigarettes, Active Nicotine Patch
- Where
- 2 sites in United States
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Alzheimer's Disease (AD), Progressive Supranuclear Palsy (PSP)
Evaluation of [18F]MNI-815 as a Potential PET Radioligand for Imaging Tau Protein in the Brain of Patients With Tauopathies
The overall goal of this imaging trial is to characterize [18F]MNI-815, a PET radioligand for imaging Tau.
- Conditions
- Alzheimer's Disease (AD), Progressive Supranuclear Palsy (PSP), Cortical Basal Syndrome (CBS), Frontal Temporal Dementia (FTD)
- Trial name
- NCT02531360
- Testing
- [18F]MNI-815 (MNI-815)
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Molecular NeuroImaging
Alcohol Dependence
Citalopram Effects on Craving and Dopamine Receptor Availability in Alcoholics
Alcohol use disorders (AUDs) are highly prevalent among U.S. civilians, and even more prevalent in the U.S. Veteran population. AUDs are frequently co-morbid with depressive symptoms in psychiatric clinical populations, resulting…
- Trial name
- CECDRAAD (NCT01657760)
- Testing
- citalopram
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Dyslexia
Speech and Short-term Memory Functions in Dyslexia: a Combined MEG and EEG Study
Developmental dyslexia is a highly heritable disorder in which reading skills are compromised despite normal intelligence and appropriate reading instruction.
- Trial name
- SMeDy (NCT02622360)
- Where
- Finland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Major Depressive Disorder (MDD), fNIRS
Prediction of REsponse to Depression Interventions (Accelerated rTMS) Using Clinical and TD-fNIRS Measurements
This observational, longitudinal, multi-cohort study aims to evaluate functional brain activity in adults undergoing treatment for Major Depressive Disorder (MDD) at participating clinical sites.
- Trial name
- PREDICT-ACC (NCT07294924)
- Testing
- fNIRS measurement
- Where
- 2 sites in United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Kernel
Generalized Anxiety Disorder
Evaluating The Effects Of Cimetidine On The Elimination Of PD 0332334 From The Body
The purpose of this study is to estimate the effects of multiple doses of cimetidine on the pharmacokinetics of a single dose of PD 0332334 and to evaluate the safety and tolerability of PD 0332334 when co-administered with…
- Trial name
- NCT00800280
- Testing
- PD 0332334, cimetidine
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
ADHD
Mindfulness Training in Adults With ADHD
The primary aim of this study is to investigate clinical effectiveness of mindfulness training versus treatment as usual (TAU) in adults with Attention Deficit Hyperactivity Disorder (ADHD).
- Trial name
- NCT02463396
- Testing
- MBCT for ADHD
- Where
- Netherlands
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Post-Traumatic Stress Disorder
Effect of Propranolol on Preventing Posttraumatic Stress Disorder
This study will assess the effectiveness of taking propranolol soon after a traumatizing incident in reducing the incidence and severity of posttraumatic stress disorder in acutely traumatized individuals.
- Trial name
- NCT00158262
- Testing
- Propranolol
- Where
- 2 sites in United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Alzheimer Disease, Cognitive Impairment
Impact of Physical Activity on Successful Aging
Emerging literature suggests that vascular factors might be involved in the pathogenesis of Alzheimer's disease (AD). Other recent studies demonstrate the positive effects of physical activity on cognitive and behavioral…
- Conditions
- Alzheimer Disease, Cognitive Impairment, Physical Activity
- Trial name
- NCT03034746
- Testing
- Physical activity (PA), cognitive treatment (CT)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Bipolar Disorder
Study of Bipolar Disorders and Retinal Electrophysiological Markers
The BIMAR study aims to compare electrophysiological data measured with electroretinogram (ERG) and electroencephalogram (EEG) between a group of euthymic patients with bipolar disorder (BD) and a group of healthy controls…
- Trial name
- BIMAR (NCT05161546)
- Testing
- EEG and ERG measurements (Retinaute®, BioSerenity), Actigraphy (Motion Watch 8®, CamNtech), Neuropsychological assessments
- Where
- France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Centre Psychothérapique de Nancy
Schizophrenia
Phase I Study to Evaluate the Safety and Pharmacokinetics of Oral Doses of Anvylic-3288 in Healthy Subjects
This is a brief inpatient study to determine the safety of a new drug in healthy people.
- Trial name
- AVL3288 (NCT01851603)
- Testing
- AVL-3288
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Infertility, Female, Trauma, Psychological
Adverse Childhood Experiences and Infertility : ACESI
Adverse childhood experiences can have powerful effects on health and quality of life in adulthood. Thus, having a history of childhood trauma, before the age of 18 (physical aggression, sexual abuse, death of a close person…
- Conditions
- Infertility, Female, Trauma, Psychological, Child Development, Child Abuse
- Trial name
- ACESI (NCT05952427)
- Testing
- ACE Questionnaire
- Volunteers
- 332 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Alzheimer Disease
A Study to Investigate Safety and Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-63733657 in Healthy Subjects and Subjects With Alzheimer's Disease
The purpose of this study is to assess the safety and tolerability of JNJ-63733657 following single ascending intravenous (IV) dose administration in healthy subjects (Part 1) and multiple ascending IV dose administrations in…
- Trial name
- NCT03375697
- Testing
- JNJ-63733657
- Where
- 7 sites in Belgium, Germany and 2 more
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Generalized Anxiety Disorder
Pharmacokinetic Study of Buagafuran Capsules in Participants With Hepatic Impairment and Normal Hepatic Function
This study adopts a non-randomized, open label, parallel, single-dose design to evaluate the safety and pharmacokinetic characteristics of Buagafuran capsules in participants with hepatic impairment.
- Trial name
- NCT07457190
- Testing
- Buagafuran
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Beijing Union Pharmaceutical Factory Ltd
Alzheimers Disease
Use of [123I] AV39 and SPECT Imaging as a Marker of Protein Disposition in Subjects With Alzheimer Disease Compared to Healthy Subjects
The underlying goal of this study is to assess 123-I AV39 SPECT imaging as a tool to detect ß-amyloid deposition in the brain of AD research participants and age- and gender-matched healthy subjects.
- Trial name
- NCT00439010
- Testing
- [123I] AV 39
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Molecular NeuroImaging
Health Care Utilization, Nursing Caries
The Effect of Tele-Nursing on Parents of Circumcised Children
Circumcision is applied in many regions of the world for cultural, social, religious and medical reasons. Considering the frequency of circumcision in the World is 30%, this rate is close to 100% in Turkey.
- Trial name
- NCT05541913
- Testing
- Tele nursing
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Duzce University
Autism Spectrum Disorder, Autism
Faecal Microbiota Analysis in Neurotypical and Autism Syndrome Disorder Siblings
This study aims to accurately characterise the gut microbiota composition of faeces of children with ASD and compare it with the gut microbiota composition of their neurotypical siblings.
- Trial name
- FAMILY (NCT05794620)
- Testing
- Stool sample
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- East Suffolk and North Essex NHS Foundation Trust
Posture, Balance
Training Balance Among People With Neurodevelopmental Disabilities
This study is a case control pilot study to investigate the impact of a short-term intervention on training anticipatory postural adjustments in a population of people with neurodevelopmental disabilities.
- Conditions
- Posture, Balance, Cerebral Palsy, Autism
- Trial name
- TAPAS (NCT04293120)
- Testing
- Training with weighted ball
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Hartford
Anxiety Disorders, Depressive Disorder
Transdiagnostic Treatment Personalization
The primary purpose of this study is to explore whether the efficiency of treatment for anxiety and depressive disorders can be increased using two discrete strategies: personalized skill ordering and 2) treatment discontinuation…
- Conditions
- Anxiety Disorders, Depressive Disorder, Post Traumatic Stress Disorder, Obsessive-Compulsive Disorder
- Trial name
- NCT04584879
- Testing
- Standard UP Treatment, Capitalization UP Treatment, Compensation UP Treatment
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Shannon E. Sauer-Zavala
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