Clinical trials: Psychiatric Disorders
Psychological Distress, Anxiety Symptoms
Exer-WAPA Project: Physical Exercise on Women's Affective and Physical HeAlth
The Physical Exercise on Women's Affective and Physical HeAlth (Exer-WAPA) project is a randomized controlled trial (RCT) designed to evaluate the effects of a supervised, group-based exercise program incorporating…
- Conditions
- Psychological Distress, Anxiety Symptoms, Depression Symptoms
- Trial name
- Exer-WAPA (NCT07466979)
- Testing
- Supervised Concurrent Exercise (Exer-WAPA)
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Schizophrenia
Phase I Study to Evaluate the Safety and Pharmacokinetics of Oral Doses of Anvylic-3288 in Healthy Subjects
This is a brief inpatient study to determine the safety of a new drug in healthy people.
- Trial name
- AVL3288 (NCT01851603)
- Testing
- AVL-3288
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Alcohol Addiction
Study of the Opioid Modulation of the Effect of Alcohol on the Dopaminergic Reward System
About 10% of the calculable loss of health and quality of life in industrial countries can be attributed to excessive alcohol consumption.
- Trial name
- NCT03854942
- Testing
- Naltrexone
- Where
- Germany
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University
Insomnia
Playing Cognitive Games For Older Adults With Insomnia
The purpose of this research is to look at the effects of computerized cognitive training on sleep, mental abilities (cognition), and other aspects of daytime functioning, such as mood, and arousal
- Trial name
- PLAY (NCT04282642)
- Testing
- Cognitive Training, WLC (Waitlist Control)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Major Depressive Disorder
Blood Biomarkers in Major Depression
Depression is a leading cause of disability worldwide, affecting nearly 16% of the general population. Its physiopathology remains unclear.
- Trial name
- NCT02209142
- Testing
- blood prelevement, psychometric data collection
- Where
- France
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Mental Health Issue, Mental Health Disorder
Intervention to Address Disparate Mental Health Consequences of COVID-19 Pandemic on Latinx and African Newcomers
This study tests the effectiveness of a community-based peer advocacy, mutual learning, and social support intervention (Refugee and Immigrant Well-being Project) to reduce several negative consequences of the COVID-19 pandemic…
- Conditions
- Mental Health Issue, Mental Health Disorder, Stress, Emotional, Economic Problems
- Trial name
- RIWP+ (NCT05092542)
- Testing
- Refugee and Immigrant Well-being Project (RIWP)
- Where
- United States
- Volunteers
- 1,212 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Substance-Related Disorders
Neurobiology and Pharmacokinets of Acute MDMA Administration
Background: 3,4-Methylenedioxymethamphetamine (MDMA), commonly known as ecstasy, is a synthetic psychoactive drug that has shown a steep increase in recreational use and abuse by young people in recent years.
- Trial name
- NCT01148342
- Testing
- MDMA, (+/-)3,4-methylenedioxymethamphetamine Hydrochloride, MDMA HCI Capsules
- Where
- United States
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Breast Cancer, Lymphoma
Adolescent and Young Adult Cancer Patients: Cognitive Toxicity on Survivorship (ACTS)
This study aims to evaluate the prevalence, biological mechanism and survivorship impact of cognitive toxicity among adolescent and young adult (AYA) patients diagnosed with curable cancers.
- Conditions
- Breast Cancer, Lymphoma, Germ Cell Tumor, Cognitive Impairment
- Trial name
- NCT03476070
- Where
- 3 sites in Singapore
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Bipolar Disorder, Major Depressive Disorder
Complex Dynamic Systems in Mood Disorders
Complex Dynamic Systems in Mood Disorders is an observational, exploratory study of the relationship between voice samples, heart rate, respiration, movement, galvanic skin conductance, and sleep architecture with mood states in…
- Trial name
- NCT01583569
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Perioperative Care, EEG Power Spectra
Extended Emergence Strategy on Post-Anesthesia Care Unit Events After Outpatient Orthopedic Surgery
The goal of this clinical trial is to learn if an extended emergence from anesthesia can improve recovery room (Post-Anesthesia Care Unit or PACU) outcomes in lower-leg or foot surgery with nerve blocks.
- Conditions
- Perioperative Care, EEG Power Spectra, Delirium - Postoperative
- Trial name
- PACU-EMERGE (NCT07533370)
- Testing
- Standard of Care EEG-Guided Emergence, Extended EEG Emergence Trajectory
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Harrison Shong-Wen Chow
Schizophrenia
A Neurobiological Study on Heterogeneity of Schizophrenia: Genetic Variations and Neurobiological Differentiations
Schizophrenia (SCH) is a devastating brain disorder with grave personal, family and social cost. SCH is a complex and heterogeneous (both genetic and clinical) disorder with oligogenetic endowed vulnerability risk of disease…
- Trial name
- SONPOS (NCT01075373)
- Where
- Taiwan
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Nursing Education, Nursing Process
GENERATİVE AI-SUPPORTED NURSİNG PROCESS EDUCATİON AND NURSİNG STUDENTS' LEARNİNG OUTCOMES
This randomized controlled trial evaluated the effect of generative artificial intelligence (AI)-supported education in teaching the nursing process on nursing students' learning outcomes.
- Conditions
- Nursing Education, Nursing Process, Learning Outcome, Generative Artificial Intelligence
- Trial name
- NCT07905040
- Testing
- Generative AI-Supported Nursing Process Education, Case Study-Based Nursing Process Education
- Where
- Turkey (Türkiye)
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Sleep Bruxism, Tension Headache
Treatment Sleep Bruxism With the Luco Hybrid OSA Appliance
To determine the effectiveness of the Luco Hybrid OSA Appliance in the treatment of sleep bruxism and to aid in the treatment of associated tension/migraine type headaches in adults.
- Conditions
- Sleep Bruxism, Tension Headache, Migraine Headache
- Trial name
- LucoHybrid (NCT02882880)
- Testing
- The Luco Hybrid OSA Appliance
- Where
- Canada
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Luco Hybrid OSA Appliance Inc.
Post-traumatic Stress Disorders
Tetris to Reduce Intrusive Memories in Parents After PICU
The purpose of this study is to examine the acceptability and feasibility of a brief behavioural intervention involving Tetris gameplay to prevent intrusive traumatic memories in parents after paediatric intensive care.
- Trial name
- NCT04186962
- Testing
- Behavioral: Simple cognitive task
- Where
- 2 sites in United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- King's College London
Opioid Use, Unspecified, Prescription Drug Abuse (Not Dependent)
An Opioid Prescribing Nudge
Analyze baseline concurrent opioid prescribing metrics at the individual prescriber level in the Duke Health System on the identified three main outcome measures.
- Conditions
- Opioid Use, Unspecified, Prescription Drug Abuse (Not Dependent), Prescription Drug Abuse and Dependency, Health Behavior
- Trial name
- OHS (NCT04069403)
- Testing
- Automated Reports on prescription patterns for their patients
- Where
- United States
- Volunteers
- 427 people, healthy volunteers welcome
- Sponsor
- Duke University
Post-traumatic Stress Disorder (PTSD), Postpartum Mental Health
A Computer Game for Postpartum Mental Health After Emergency Cesarean Birth
This study aims to explore whether playing the computer game Tetris can reduce PTSD symptoms in women who have undergone emergency caesarean births.
- Trial name
- NCT07290127
- Testing
- implementation of a brief computer-based intervention "Tetris"
- Where
- Japan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Kyoto University, Graduate School of Medicine
Seasonal Allergic Rhinitis
Fluticasone Furoate Treatment of Daytime Somnolence and Cognitive Performance in Seasonal Allergic Rhinitis
The hypothesis is that treating hay fever patients who had daytime sleepiness and slowed thinking because of the hay fever will improve when treated with an effective anti-hay fever medication, an intranasal steroid, that is will…
- Trial name
- NCT00997620
- Testing
- Fluticasone furoate Nasal Spray 110 mcg
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Western Sky Medical Research
Opioid Dependence
XRB vs. SLB in Jail and at Re-entry: Pilot, Proof of Concept
This is a pilot proof-of-concept randomized controlled trial, open-label and unblinded, examining the feasibility and acceptability of Buprenorphine extended-release vs.
- Trial name
- NCT03604159
- Testing
- Buprenorphine Extended Release, Sublingual Buprenorphine (SUBOXONE, Zubsolv, or generic tablets)
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Sleep Disturbance, Mental Health Issue
Sweet Scents to Sweet Dreams
The purpose of this study is to determine the effect of herbal pillows on sleep and quality of life in a healthy population using actigraphy, validated questionnaires and daily diary logs.
- Trial name
- SSS (NCT06247696)
- Testing
- Herbal Pillows
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Duquesne University
Insomnia
Insomnia in Older Adults: Impact of Personalized, Diet-Induced Alterations in the Microbiota
Insomnia is a chronic mental health condition characterized by difficulty initiating and maintaining sleep with a prevalence of over 50% in Israeli adults ages 65 and above.
- Trial name
- NCT03085446
- Testing
- PDM nutritional intervention, General information on nutrition and health
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Haifa
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