Clinical trials: Psychiatric Disorders
Substance Abuse
Web-delivery of Evidence-based, Psychosocial Treatment for Substance Use Disorders
The main objective of this study is to evaluate the effectiveness of including an interactive, web-based version of the Community Reinforcement Approach (CRA), called the Therapeutic Education System (TES), as part of…
- Trial name
- CTN-0044 (NCT01104805)
- Testing
- Therapeutic Education System (TES), Treatment-as-Usual (TAU)
- Where
- 10 sites in United States
- Volunteers
- 507 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Substance-Related Disorders
Disrupting SRFOH to Improve Substance Use and Mental Health Outcomes for Parents in Rural Regions
The study will evaluate the effectiveness of the Just Care for Families program in preventing Oregon Department of Human Services (ODHS)-involved parents in rural communities from escalating opioid and/or methamphetamine use and…
- Trial name
- NCT06560866
- Testing
- Just Care for Families
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Chestnut Health Systems
Anxiety and Fear
The Effect of Virtual Reality Glasses Used During Intravenous Catheter Insertion
The purpose of this clinical trial is to evaluate the effect of the virtual reality glasses device on the child's emotional responses during invasive interventions in child health services.
- Trial name
- NCT06189222
- Testing
- virtual reality glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Türkan Şen
Alzheimer's Disease
A Multiple Ascending Dose Study of BPN14770 in Healthy Young and Elderly Male or Female Subjects
This is a randomized, double-blind (Investigator and subject-blinded) placebo-controlled, multiple, ascending-dose study to evaluate the safety, tolerability, and pharmacokinetic profile of BPN14770 in healthy young and elderly…
- Trial name
- NCT02840279
- Testing
- BPN14770
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Tetra Discovery Partners
Mental Health Issue, Depressive Symptoms
Piloting +Connection is Medicine / The Healing Spirits Program
This study aims to assess what benefit, if any, an individualized coping plan and facilitating connections to care through referral coordination in conjunction with culturally tailored caring messages, (herein called the…
- Conditions
- Mental Health Issue, Depressive Symptoms, Anxiety
- Trial name
- NCT05424679
- Testing
- Safety Planning Intervention, Caring Contacts
- Where
- 4 sites in United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Neurodegenerative Diseases, Alzheimer Disease
Exploratory Evaluation of [11C]MPC6827
This is a phase 0 study that will enable an assessment of biodistribution and estimation of absorbed dose in humans based on data collected from five healthy volunteers, which is typically the minimum number required by the FDA…
- Conditions
- Neurodegenerative Diseases, Alzheimer Disease, Amyotrophic Lateral Sclerosis
- Trial name
- NCT04575727
- Testing
- [11C]MPC6827
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Columbia University
Alcohol Abuse Alcoholism, General Practice
Identification and Treatment of Alcohol Problems in Primary Care
The Identification and Treatment of Alcohol Problems in Primary Care (iTAPP) Study is a pragmatic cluster randomized controlled intervention trial evaluating the effectiveness of the 15-Method as an identification and treatment…
- Conditions
- Alcohol Abuse Alcoholism, General Practice, Screening and Brief Intervention
- Trial name
- iTAPP (NCT05916027)
- Testing
- The 15-Method
- Where
- Denmark
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Maternal Distress
Essential Coaching for Every Mother, a Postpartum Text Message Program for Canadian Mothers
The purpose of this study is to evaluate a text message-based program called Essential Coaching for Every Mother which sends daily text messages during the immediate six-week postnatal period.
- Trial name
- ECEM (NCT04730570)
- Testing
- Essential Coaching for Every Mother
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Mild Cognitive Impairment
Metformin in Alzheimer's Dementia Prevention
MAP will be a multi-center phase 2/3 1:1 randomized controlled trial (RCT) of long-acting metformin (reduced mass Glucophage XR) vs.
- Trial name
- MAP (NCT04098666)
- Testing
- extended release metformin
- Where
- 22 sites in United States
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Columbia University
Schizophrenia, Clozapine
Effect of Exercise on Clinical Symptoms, Cognitive Performance, and Quality of Life in Schizophrenia Patients Treated With Clozapine
This prospective study aims to investigate the effects of exercise on clinical symptoms, cognitive performance, and quality of life in schizophrenia patients treated with Clozapine.
- Conditions
- Schizophrenia, Clozapine, Exercise
- Trial name
- NCT06573320
- Testing
- physical exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Independent Living, Disability Free Survival
A Clinical Trial of STAtin Therapy for Reducing Events in the Elderly (STAREE)
The STAREE study will examine whether treatment with statin (atorvastatin 40mg) compared with placebo will prolong disability free survival and reduce major cardiovascular events amongst healthy elderly people (≥70 years).
- Conditions
- Independent Living, Disability Free Survival, Elderly, Healthy
- Trial name
- STAREE (NCT02099123)
- Testing
- Atorvastatin
- Where
- 6 sites in Australia
- Volunteers
- 9,971 people, healthy volunteers welcome
- Sponsor
- Monash University
Major Depression
Multicenter Comparative Study of the Activity of the Medial Prefrontal Cortex in Vulnerability to Depression
To examine whether the medial prefrontal cortex displays an increased activity during self-referential processing among remitted depressed patients compared to healthy controls
- Trial name
- CORVAD (NCT02171923)
- Where
- France
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Anxiety, Stress Disorder, Posttraumatic
BLOOM: Boldly Living outdOOrs for Mental Health
In 2019, the Office of the California Surgeon General launched the ACEs Aware Initiative in collaboration with the California Department of Health Care Services.
- Conditions
- Anxiety, Stress Disorder, Posttraumatic, Loneliness, Adverse Childhood Experiences
- Trial name
- BLOOM (NCT05973123)
- Testing
- Group Nature Outings, Family Outings
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Healthy Adult Participants, Acute Stress Reaction
Breathwork and Stress: Investigating the Mechanisms of Action and Effectiveness of Breathing Interventions in Modulating the Psychophysiological Response to Acute Stress Test
This study investigates whether the psychophysiological benefits of breathing exercises are driven by a specific physiological rhythm (6 breaths per minute) or by the general psychological experience of performing a structured…
- Conditions
- Healthy Adult Participants, Acute Stress Reaction, Stress Biomarkers, Healthy
- Trial name
- NCT07529379
- Testing
- Coherent Breathing (6 bpm)
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medical University of Bialystok
Mild Cognitive Impairment
Cognitive Detection of Preclinical AD: Validation Using Biomarkers
The current study aims to validate several novel cognitive tasks expected to be sensitive to brain impairment in specific anatomic regions affected in preclinical Alzheimer's disease(pAD).
- Trial name
- NCT02616679
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Scheduled Surgery, Healthy Volunteers
Validation of the French Version of the Pain Sensitivity Questionnaire
The Pain Sensitivity Questionnaire (PSQ) is a tool created in 2009 by Dr. R. Ruscheweyh in Germany. It aims at identifying the natural sensitivity to pain, through a set of 17 simple questions.
- Trial name
- PSQ-F (NCT03113903)
- Testing
- Psychophysical exploration
- Where
- France
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Healthy
A Multiple Ascending Dose Study of BCI-838 in Healthy Volunteers
This study will evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of BCI-838 and its metabolite BCI-632 in healthy male and female subjects.
- Trial name
- NCT01548703
- Testing
- BCI-838
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- BrainCells Inc.
Attention Deficit Hyperactivity Disorder
Clinical Trial to Evaluate the Efficacy and the Tolerance of an Omega 3 Fatty Acids Supplementation in ADHD Children
Principal focus is to evaluate the effects of omega 3 fatty acids supplementation on the ADHD children's behaviour during 12 weeks on two years.
- Trial name
- NCT00770627
- Testing
- Omega 3 caps
- Where
- 2 sites in France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Laboratoires URGO
Alzheimer's Disease, Mild Cognitive Impairment
Effectiveness of an Electronic Training Program for Orienting and Interpreting [18F]Flutemetamol Positron Emission Tomography (PET) Images
To Evaluate the Effectiveness of an Electronic Training Program for Orienting and Interpreting [18F]flutemetamol Positron Emission Tomography (PET) Images.
- Trial name
- NCT01672827
- Testing
- [18F]Flutemetamol
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
HIV/AIDS, Hepatitis C
Project I Test: Implementing HIV Testing in Opioid Treatment Programs
This study will test two active evidence-based "practice coaching" (PC) interventions to improve opioid treatment programs' (OTPs') provision and sustained implementation of on-site 1) HIV testing and linkage to care and 2)…
- Conditions
- HIV/AIDS, Hepatitis C, Substance Use Disorders, Opioid-use Disorder
- Trial name
- NCT03135886
- Testing
- Information Control, HIV and HCV Testing Practice Coaching Intervention, HIV Testing Practice Coaching Intervention
- Where
- United States
- Volunteers
- 418 people, healthy volunteers welcome
- Sponsor
- Columbia University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.