Clinical trials: Psychiatric Disorders
Alzheimer Dementia
Reappraising Intergeneration Relationships in Dementia Caregiving
It is hypothesized that reappraising intergeneration relationships through perspective-taking will enhance the well-being of adult-child caregivers.
- Trial name
- NCT03584568
- Testing
- Perspective Taking Reappraisal, Basic Skill Building
- Where
- 2 sites in Hong Kong
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Panic Disorder
Efficacy of Treatment for Panic Disorder
The purpose of these questionnaires is to give us an overview of how panic has affected your life and perhaps also to give us some clues about things that may have set you up to experience panic.
- Trial name
- NCT00456768
- Where
- Canada
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
PTSD
Post-Traumatic Stress Disorder (PTSD) Symptom Study
The primary goals for this investigation are to quantify: (1) fluctuations in PTSD symptom reports when assessed at bi-weekly intervals; (2) change in PTSD symptoms associated with stressful life events; and (3) change in PTSD…
- Trial name
- NCT00018798
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Anxiety, Postoperative Pain
Sublingual Melatonin for Anxiety and Pain in Elective Gynecologic Surgery
This prospective randomized controlled study aims to evaluate the anxiolytic effect of preoperative sublingual melatonin and its impact on postoperative pain scores when administered in two different doses to female patients…
- Conditions
- Anxiety, Postoperative Pain, Anesthesia
- Trial name
- NCT06997263
- Testing
- Melatonin 3 mg Sublingual, Melatonin 6 mg Sublingual
- Where
- Egypt
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Benha University
Cesarean Section Complications
The Effect of Virtual Reality Application on Perceived Anxiety and Vital Signs in Primiparous
Purpose: To determine the effect of virtual reality application on anxiety and vital signs perceived by primiparous women during cesarean section.The research was conducted in a randomized controlled experimental design.The…
- Trial name
- NCT06336421
- Testing
- Virtual Reality
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Social Isolation or Loneliness, Anxiety
Health Surveillance at University of Applied Science Hamburg (HAW)
The aim of Health Surveillance 2025 is to analyze and describe the state of health of employees at University of Applied Science Hamburg, key influencing factors and individual resources.
- Conditions
- Social Isolation or Loneliness, Anxiety, Anxiety Acute, Anxiety Depression
- Trial name
- HAW_HS2025 (NCT07089914)
- Where
- Germany
- Volunteers
- 679 people, healthy volunteers welcome
- Sponsor
- Jacobs University Bremen gGmbH
Day Surgery
Education for Children Who Will Have Planned Surgery With Web-based and Therapeutic Game Method
This research was planned to determine the effects of the web-based education given at home to children aged 7-12 in planned surgeries and the therapeutic game method applied in the hospital on pre-operative anxiety and fear…
- Trial name
- NCT05320614
- Testing
- Web-Based Education, Routine maintenance Training
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Muğla Sıtkı Koçman University
Parkinson Disease, Amyotrophic Lateral Sclerosis (ALS)
Discovery and Validation of Protein Structural Complexes in Circulating Biofluids As Novel Biomarkers for Early Diagnosis, Prognosis and Therapeutic Management of Patients Affected by Neurodegenerative Disorders
Neurodegenerative disorders (NDDs), such as Parkinson¿s disease (PD), Alzheimer¿s disease (AD), Frontotemporal dementia (FTD) and Amyotrophic Lateral Sclerosis (ALS) are characterized by aggregation and intracellular accumulation…
- Conditions
- Parkinson Disease, Amyotrophic Lateral Sclerosis (ALS), Frontotemporal Dementia (FTD), Alzheimer's Disease (AD)
- Trial name
- NCT06803784
- Testing
- Genetic: whole genome sequencing, whole exome sequencing
- Where
- Italy
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Neuromed IRCCS
Schizophrenia and Other Psychotic Disorders, Healthy Adult
Dysfunction of Respiratory Enzymes in Adults With Mental Illness (DREAM)
This study tested whether intravenous methylene blue changes brain activity during a working-memory task differently in adults with schizophrenia taking stable antipsychotic medication and healthy volunteers.
- Trial name
- DREAM (NCT07866833)
- Testing
- Methylene Blue
- Where
- United Kingdom
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- King's College London
Mood Disturbance
Effect of Saffron Extract Supplementation on Emotional Well-being Alterations
This study aims to test whether a saffron extract represents a good candidate to improve emotional well-being in subjects with subclinical symptoms of depression, fatigue, stress or anxiety.
- Trial name
- SAFFROMFOOD (NCT05690126)
- Testing
- Saffron extract, Maltodextrin
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Mild Cognitive Impairment, Alzheimer's Disease
A Double-Blind, Placebo-Controlled, Dose Ranging Study of Xanamem® in Healthy Elderly Volunteers
Xanamem® is being developed as a potential drug for Mild Cognitive Impairment in Alzheimer's disease. This study drug has been designed to change the cortisol levels in the brain.
- Trial name
- XanaMIA-DR (NCT04983368)
- Testing
- Xanamem® 5 mg, Xanamem® 10 mg
- Where
- 5 sites in Australia
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Actinogen Medical
Anxiety and Depression, Disorders of Gut-brain Interaction
Development of an Online ACT Intervention for Disorders of Gut-Brain Interaction
The goal of this clinical trial is to develop and test the iACTforDGBI intervention in a sample of Swedish individuals with DGBI (Disorders of Gut-Brain Interaction).
- Trial name
- iACTforDGBI (NCT06309004)
- Where
- Sweden
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Healthy, Epilepsy
Bridging Gaps in the Neuroimaging Puzzle: New Ways to Image Brain Anatomy and Function in Health and Disease Using Electroencephalography and 7 Tesla Magnetic Resonance Imaging
The human brain presents outstanding challenges to science and medicine. Brain function and structure span broad spatial scales (from single neurons to brain-wide networks) as well as temporal scales (from milliseconds to years).
- Conditions
- Healthy, Epilepsy, Psychosis, Essential Tremor
- Trial name
- NCT05769933
- Testing
- Simultaneous EEG-fMRI at 7 Tesla, Structural MRI at 7 Tesla
- Where
- Switzerland
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- CSEM Centre Suisse d'Electronique et de Microtechnique SA - Recherche et Developpement
Autism Spectrum Disorder
Training Early Social Language in Autism
The aim of the study is to determine whether a targeted behavioral intervention can lead to both changes in early communication skills and in neural responses in toddlers and preschoolers with autism.
- Trial name
- TESLA (NCT03427138)
- Testing
- Jasper, Parent Education
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Lewy Body Disease
A Phase I Study of GT300 in Healthy Subjects
Descriptive safety and pharmacokinetics of GT300, exploratory biomarker effects for the evaluation of the effect of GT300 on the autophagy-lysosomal pathway (ALP), food effect on PK and fasting effect on biomarkers.
- Trial name
- NCT04963855
- Testing
- GT300, Microcrystalline cellulose
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Generian Pharmaceuticals, Inc.
Psychological Disease
Reliability and Validity of the DIPS (Structured Interview) in a Community Sample
The DIPS (Diagnostisches Interview bei psychischen Störungen) is a structured interview to assess a variety of the most frequent psychological disorders. Its reliability and validity has been studied in clinical samples.
- Trial name
- NCT04475055
- Testing
- Diagnostisches Interview bei psychischen Störungen (DIPS)
- Where
- Germany
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Ruhr University of Bochum
Sleep Quality, Anxiety Level
Hand Massage Applied To Elderly Stayıng In Nursing Homes
Hand massage; behavioral and reduce psychological symptoms, enable individuals to calm down and relax, and provide individual and care It is applied to contribute to communication between donors, to ensure reliability and ease of…
- Trial name
- NCT06872008
- Testing
- Hand Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Amasya University
Alzheimer Disease
Longitudinal Imaging of Microglial Activation in Different Clinical Variants of Alzheimer's Disease
The purpose of this study is to determine how inflammation is related to other changes in the brain that occur during the progression of Alzheimer's disease.
- Trial name
- ADVISe (NCT04576793)
- Testing
- 11C-ER176, 18F-MK6240, 18F-Florbetaben
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Columbia University
Attention Deficit Hyperactivity Disorder
Sensory-Play Based (SenPlay) Intervention for Young Children With or At Risk for ADHD
The purpose of this pilot study is to determine the effects of 15 minutes of sensory-play based (SenPlay) intervention on improving focused attention in developmentally appropriate tasks in young children with or at risk for ADHD.
- Trial name
- NCT05222321
- Testing
- Sensory-Play Based (SenPlay) Intervention, Spontaneous, Free Play
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Cognition Disorder, Functional Brain Imaging
fMRI and NIRS Imaging for Traumatic Brain Injury
Background: The amount of blood flowing in brain areas goes up when those areas are being used for activities, such as movement or seeing.
- Trial name
- NCT01668758
- Volunteers
- healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
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