Clinical trials: Psychiatric Disorders
Attention Deficit-Hyperactivity Disorder
Influence of Stimulant Medication on Brain Processes for Decision Making in Attention Deficit Hyperactivity Disorder
The goal of this trial is to investigate the cognitive- and brain-mechanisms underlying decision making (DM) and learning in young adults with Attention-Deficit/Hyperactivity Disorder (ADHD) as well as the modulation of…
- Trial name
- NCT01831622
- Testing
- Ritalin
- Where
- 2 sites in Norway
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Mats Fredriksen
Opioid-use Disorder
Evaluation of Intranasal Naltrexone and Naloxone
This study will be to determine the pharmacokinetics of naltrexone and naloxone when administered via intranasal separately and in combination in healthy volunteers.
- Trial name
- NCT03851731
- Testing
- Naltrexone, Naloxone, Naltrexol
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Tobacco Abstinence
Varenicline For Smokers In Recovery From Alcohol Dependence
The goal of this proposal is to explore the potential effectiveness of varenicline to treat tobacco dependence among recovering alcoholic smokers who, as a group, are at high risk for tobacco-caused morbidity and mortality.
- Trial name
- NCT01092702
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Alzheimer's Disease
Drug Interaction Study Between AZD3480 and Warfarin
The purpose of the study is to evaluate if AZD3480 and warfarin interact with each other or not, i.e. show the same or altered plasma concentration profiles when co-administered compared to administered alone.
- Trial name
- DDI (NCT00689637)
- Testing
- AZD3480, Warfarin
- Where
- Sweden
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Dementia, Oral Hygiene
Oral Health, Bite Force and Dementia
Study aims: The primary aim is to identify influencing variables on oral hygiene / oral health and bite force in patients with dementia.
- Conditions
- Dementia, Oral Hygiene, Chewing Problem
- Trial name
- OrBiD (NCT03775772)
- Testing
- Oral Health, Bite Force
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Anxiety, Opioid Consumption
Associations Between Analgesia Nociception Index and Preoperative Anxiety
The management and prediction of pain is one of the most crucial jobs for anesthetists. It has been shown that a patient's ability to remain calm during stressful situations is related to their post-surgical pain scores.
- Conditions
- Anxiety, Opioid Consumption, Cesarean Section
- Trial name
- PANIC (NCT04875572)
- Testing
- Analgesia Nociception Index (ANI) Monitor
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Substance Abuse, Chronic Pain
Physician Coaching to Reduce Opioid-related Harms
This project pilot tests an innovative clinical guideline translation and physician coaching model to promote adherence to evidence-based guidelines for the prescribing of opioid pain medications in primary care settings.
- Trial name
- NCT02433496
- Testing
- Physician coaching
- Where
- United States
- Volunteers
- 53,132 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Gestational Diabetes
Pregnancy on Oral Glucose Tolerance Test Implementation Status, Knowledge, and Anxiety Level
This study was planned to examine the effect of video education on pregnancy for oral glucose tolerance test implementation status, knowledge and anxiety level.
- Trial name
- NCT05686694
- Testing
- Video Education
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Ege University
Schizophrenia, Cannabis Use Disorder
Genetic Basis of the Risk and Consequences of Cannabis Exposure in Humans
Cannabis is widely used worldwide and is associated with negative outcomes including cannabis use disorder (CanUD), psychosis, and cognitive impairment amongst others.
- Trial name
- NCT06058702
- Testing
- Delta-9-THC Very Low Dose, Delta-9-THC Medium Dose
- Where
- United States
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- Yale University
Opioid-Related Disorders, Substance-Related Disorders
Effects of Nitrous Oxide: A Dose-Response Analysis - 5
The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used…
- Trial name
- NCT00000253
- Testing
- 10% N2O, 20% N2O, 30% N2O
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Schizophrenia, Bipolar Disorder
Characterization of Emotional Processing of Information in Bipolar Disorder and Schizophrenic Patients
In the case of psychotic disorders such as bipolar disorder or schizophrenia, attention dysfunction contribute, according to the theories of neuroscience, the development of mood disorders following disturbances in the…
- Trial name
- EMOBISCHI (NCT02841345)
- Testing
- behavioral and fMRI
- Where
- France
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Menopause, Perimenopause
Effects of Hemp-Derived Cannabinoids on Menopause Symptoms
The purpose of the study is to examine the impact of hemp-derived minor cannabinoids on symptoms of menopause/perimenopause.
- Trial name
- NCT07393672
- Testing
- Hemp-derived cannabinoids
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Washington State University
Pain Management
The Effect of Mindfulness-Based Stress Reduction Training Before Mastectomy on Postoperative Pain in Early Period
This research aims to investigate the effect of mindfulness-based stress reduction training given before mastectomy on postoperative early period pain and the fear of movement caused by pain.
- Trial name
- NCT06349395
- Testing
- MBSR surgical nursing care
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul Nisantasi University
Cancer, Chemotherapy Effect
The Effect of Sujok Therapy on Patient Comfort, Pain Intensity, and Anxiety Level in Cancer Patients With Port Catheter Placement
Cancer is a fatal disease characterized by uncontrolled growth and proliferation of tissues and organs in the human body. Among cancer treatments, chemotherapy is the most commonly used treatment method.
- Trial name
- NCT06430177
- Testing
- Su Jok
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Firat University
Alzheimer Disease
Safety, Tolerability and Pharmacokinetics of AD16 Tablets After MAD in Healthy Chinese Adult Subjects
This single-center, randomized, placebo-controlled, double-blind, dose-increasing study was designed to evaluate the safety, tolerability, and pharmacokinetics of multiple successive dosing in healthy Chinese adult subjects.In…
- Trial name
- MAD (NCT05806177)
- Testing
- AD16 30mg、40mg
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- South China Center For Innovative Pharmaceuticals
Posttraumatic Stress Disorder
A Controlled Breathing Course for Social & Emotional Health for Vietnam Veterans With Chronic PTSD-RCT
The main aim of this project is to evaluate the use of a specific Yoga technique of controlled breathing in Vietnam War Veterans with chronic posttraumatic stress disorder.
- Trial name
- NCT00256477
- Testing
- Sudarshan KRIYA Breathing Technique
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Queensland
Autism Spectrum Disorder
The Effect of Digital Storytelling and Sensory Integration on Children With Autism
Given the interest of children with Autism Spectrum Disorder (ASD) in using computers, this study examined the effect of Digital Storytelling (DST) activity on increasing activity participation and self-regulation.
- Trial name
- NCT06491875
- Testing
- Digital Storytelling (DST), Sensory Integration Therapy (SIT)
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Biruni University
Autism Spectrum Disorder, Typical Development
Improving Social Interaction for Adolescents With Autism During the Transition to Adulthood
This study compares the efficacy of two intervention strategies for improving social outcomes for autistic adolescents and young adults when interacting with unfamiliar non-autistic peers.
- Trial name
- NCT03785327
- Testing
- tDCS, Autism Training
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Physical Inactivity, Ultra Processed Food
Online Intervention for Reduction of Ultra-processed Products and Increase of Physical Activity in University Students
This study evaluates the effectiveness of an online Multi-component psychological intervention, that is focused on reducing the consumption of ultra processed foods and increase the frequency of performing Physical Activity.
- Conditions
- Physical Inactivity, Ultra Processed Food, Stress, Anxiety
- Trial name
- UNISALUD (NCT05834842)
- Testing
- Unisalud
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- University of Guadalajara
Dementia
Roflumilast and Cognition
The aim of the current project is to validate PDE4 inhibitors as a target for cognition enhancers (proof-of-concept) using a translational behaviour-EEG approach.
- Trial name
- EEGrofl (NCT01433666)
- Testing
- roflumilast (EU: Daxas, USA: Daliresp), roflumilast
- Where
- Netherlands
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
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