Clinical trials: Psychiatric Disorders
Virtual Reality, Anxiety
The Effect of Virtual Reality Application on Anxiety and Patient Satisfaction During Intrauterine Insemination (IUI)
This study will conduct as a randomized pretest-posttest study to examine the effect of virtual reality glasses (VRG) application during the IUI procedure on anxiety and patient satisfaction.
- Conditions
- Virtual Reality, Anxiety, Patient Satisfaction, Intrauterine Insemination (IUI)
- Trial name
- (IUI) (NCT06346730)
- Testing
- Virtual reality glasses to intervention group
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Schizophrenia, Mental Disorders
Study of the Activation of Proinflammatory Pathways of Toll-like Receptors in Schizophrenia Patients
The study of immune pathways involved in the etiopathogeny of schizophrenia would be an important advance to understand the mechanisms involved in the development of this disease and it would be a turning point in drug therapy.
- Conditions
- Schizophrenia, Mental Disorders, Psychotic Disorders
- Trial name
- PAFIP_TLR (NCT02897167)
- Testing
- Retrospective study of frozen samples, Prospective study of fresh samples
- Where
- Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Fundación Marques de Valdecilla
Aggression, Conduct Disorder
Arousal-Biofeedback for the Treatment of Aggressive Behavior in Children and Adolescents
The purpose of this study is to determine whether individualized biofeedback of arousal (skin conductance) is effective in the treatment of aggressive behavior problems in children and adolescents with either predominantly…
- Conditions
- Aggression, Conduct Disorder, Oppositional Defiant Disorder
- Trial name
- NCT02485587
- Testing
- Individualized Arousal-Biofeedback, Treatment as usual
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Central Institute of Mental Health, Mannheim
Sleep, Sleep Disturbances in Children
Cross-sectional Study of Sleep Disturbance in Hong Kong Children With Cancer Comparing With Healthy Counterparts and Children With Other Chronic Diseases
Sleep disturbances are prevalent among children with chronic illnesses, yet the specific impact of cancer on sleep remains underexplored.
- Conditions
- Sleep, Sleep Disturbances in Children, Sleep Disturbances
- Trial name
- NCT07122921
- Where
- Hong Kong
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Risk of Dementia, Dementia
Development and Empirical Evaluation of a Brief Lifestyle Intervention for Older Adults at Risk of Dementia Within an Integrated Medical-Preventive Grid-Based Service Model
Lifestyle factors are among the most important modifiable risk factors for dementia, and primary prevention through lifestyle interventions is considered the most cost-effective approach to reducing the incidence of dementia.
- Trial name
- NCT07831616
- Testing
- Brief lifestyle intervention
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University
Cognitive Dysfunction, Cognitive Dysfunction, Cognitive Disorder
China-NINE Cohort：Neuroimmune Network in Elderly / Neurodegeneration
This is an observational study aimed at understanding the cognitive, functional, and behavioral characteristics of Chinese patients with cognitive impairment, exploring the underlying mechanisms, and providing evidence for early…
- Conditions
- Cognitive Dysfunction, Cognitive Dysfunction, Cognitive Disorder, Parkinson's Disease (PD)
- Trial name
- NCT07586501
- Where
- 2 sites in China
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Yantai Yuhuangding Hospital
Early Onset Dementia, Young Onset Dementia
Anxiety, Stress and Sleep Problems in People With Early Onset Dementia
The aim of this study is to detect and assess needs of people with early onset dementia regarding anxiety, stress and sleep implement a 6 week intervention pilot study in wich weekly (hourly) sessions are implemented in day care…
- Conditions
- Early Onset Dementia, Young Onset Dementia, Stress, Distress, Emotional
- Trial name
- Young-D (NCT05555381)
- Testing
- young-D program
- Where
- 2 sites in Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Carer Stress Syndrome, Dementia
Effects of a Modified Mindfulness-based Cognitive Therapy for Family Caregivers of People With Dementia
Caring for people with dementia (PWD) poses many challenges which may cause high levels of caregiver stress. This study aims to investigate the effects of a modified Mindfulness-based Cognitive Therapy for stress reduction in the…
- Trial name
- NCT03354819
- Testing
- Modified MBCT, SIRE on dementia
- Where
- Hong Kong
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Anxiety, Fear
An Exploratory Investigation of a CBD Supplement's Impact on Sleep, Stress, and Focus
A high-quality broad-spectrum cannabidiol supplement with a bio-terpene complex will be administered once daily. It is hypothesized that this supplement will lead to improvements in sleep, focus, and stress.
- Conditions
- Anxiety, Fear, Stress, Low Mood
- Trial name
- NCT05518019
- Testing
- The Daily Supplement
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Prima CBD
Post-Traumatic Stress Disorder
Cognitive Behavioral Therapy Versus Sertraline in the Treatment of Post-Traumatic Stress Disorder
This study will evaluate which parts of the brain are affected by treatment with behavioral therapy versus medication therapy in people with post-traumatic stress disorder.
- Trial name
- NCT00391430
- Testing
- Sertraline, Cognitive behavioral therapy (CBT)
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Breast Cancer
Magnetic Resonance Imaging (MRI) of Tumor Response and Cognitive Impairment in Breast Cancer Patients Undergoing Chemotherapy
We will use magnetic resonance imaging (MRI) to investigate tumor changes in women with breast cancer who are receiving anthracycline-based systemic chemotherapy.
- Trial name
- NCT01045044
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Kettering Health Network
Dementia, Frontotemporal
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of VES001 in Healthy Participants
This is a Phase 1, randomized, placebo-controlled, double-blind study to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of single and multiple doses of VES001 in a two part followed by a…
- Trial name
- SORT-IN-1 (NCT06226064)
- Testing
- VES001
- Where
- Netherlands
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Vesper Biotechnologies ApS
Tobacco Smoking in Mother Complicating Pregnancy, Tobacco Use Disorder
Smoking Reduction In Gravid Substance Use Disorders
The aim of this study is to encourage smoking cessation in women with substance use disorders by providing knowledge of expired carbon monoxide.
- Conditions
- Tobacco Smoking in Mother Complicating Pregnancy, Tobacco Use Disorder, Tobacco Smoking
- Trial name
- SIGS (NCT04132232)
- Testing
- knowledge of expired maternal carbon monoxide and fetal carboxyhemoglobin levels
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Virtual Reality, Episiotomy
The Effect of Virtual Reality Application on Student Satisfaction, Self-Confidence, and Anxiety Levels
The study aims to develop a virtual reality application for episiotomy training and to determine the effect of the virtual reality application on student satisfaction, self-confidence, and anxiety levels.
- Trial name
- NCT05905263
- Testing
- Application group with virtual reality
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Depression, Major Depressive Disorder
Noninvasive Physiologic Sensors to Assess Depression
This project aims to use sensors to monitor physiological signals, sleep patterns, vocal characteristics, activity, location and phone usage in study patients with depression who are receiving standard treatment (compared with…
- Trial name
- NCT02568865
- Testing
- Physiological Sensors, Sleep Monitoring Device, Vocal Monitoring
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Eating, Anxiety
Ultra-Processing and Nutritional Quality: Glycemic Response, Appetite, Dietary Energy Intake, and Eating Rate
The UPGRADE Study will examine how food-processing level and nutritional quality affect energy intake, eating rate, satiety, and glycemic response.
- Conditions
- Eating, Anxiety, Ultra Processed Food
- Trial name
- UPGRADE (NCT07808892)
- Testing
- Test Meals Differing in Processing Level and Nutritional Quality
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ariel University
Rumination
Role of Vagal Tone in Rumination Syndrome
Rumination syndrome is a condition in which people repeatedly and unintentionally regurgitate undigested or partially digested food from the stomach, rechew it, and then either re-swallow it or spit it out.
- Trial name
- NCT03912636
- Testing
- Diaphragmatic breathing, Deep Slow Breathing, Normal breathing
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Substance Dependence
Study To Investigate If Repeat Doses Of GSK598809 Are Safe And Well Tolerated And To Evaluate Blood Levels Of GSK598809
GSK598809 is being developed as an innovative treatment for substance dependence and potentially other compulsive behavioral disorders.
- Trial name
- NCT00437632
- Testing
- GSK598809, Caffeine
- Where
- United Kingdom
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
COPD
Effects of Combined Cognitive Rehabilitation in COPD Patients
This study was to examine the effect of endurance training combined with cognitive training in patients with COPD. The intervention group underwent Cognitive Training added to Endurance Training and the control group underwent…
- Trial name
- NCT03907839
- Testing
- clinical trials
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Faculty of Medicine, Sousse
Cognitive Impairment, Dementia
A Digital Life Story to Support Person-centred Care for Older Adults With Dementia Perspectives
Person-centred care can be supported when healthcare professionals access and actively use the information recorded in a life story. Active use of the life story can create security for a person with dementia and their carers.
- Trial name
- NCT06337201
- Testing
- Test of the application Min Memoria
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Blekinge Institute of Technology
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