Clinical trials: Psychiatric Disorders
Depression, Anxiety
Mental Health Impact of the COVID-19 Pandemic on Amish and Mennonite Participants in AMBiGen
People have had to make a lot of changes to their lives due to the COVID-19 health crisis. Most experts agree that social distancing and other safety measures have taken a toll on people s mental health.
- Conditions
- Depression, Anxiety, Bipolar Disorder
- Trial name
- NCT04684615
- Where
- United States
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Obsessive - Compulsive Disorder
Neural Mechanisms of the Sensorymotor Circuit in Sensory Phenomena in OCD
The goal of this clinical study is to investigate the neural mechanisms of abnormal sensory phenomena in patients with Obsessive-Compulsive Disorder and to evaluate whether modulation of the insula-supplementary motor area…
- Trial name
- NCT07480408
- Testing
- repetitive transcranial magnetic stimulation (rTMS)
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Autism, Dual Task
Single-Dual Task Performance in Children With Autism Spectrum Disorder and Typically Developing Children
This study aims to compare the effects of single-task and dual-task conditions on motor performance and postural control in children with Autism Spectrum Disorder (ASD) and typically developing children.
- Trial name
- NCT07323550
- Testing
- Single- and Dual-Task Condition Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Atlas University
Cognitively Healthy People, Alzheimer Disease
Brain Effects of Gamma Frequency Sensory Stimulation (40Hz Light, Sound and Other Devices)
Despite the huge healthcare and economic impact of AD, there is still no disease modifying therapeutics available. In fact, the available therapeutics show low efficacy at best in the treatment of cognitive impairment in…
- Trial name
- GENUS (NCT07496918)
- Testing
- GENUS, Tactile GENUS
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Massachusetts Institute of Technology
Insomnia
A Study To Investigate The Absorption, Metabolism And Excretion Of [14C] PD 0200390 In Six Healthy Male Volunteers
To determine the mass balance of PD 0200390
- Trial name
- NCT00722306
- Testing
- PD 0200390
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Pfizer
Adherence, Tobacco Use Cessation
Smoking Cessation for Young Adults Who Binge Drink - 1
The purpose of this study is develop and test the success of a new smoking cessation intervention that includes a component to eliminate binge drinking.
- Conditions
- Adherence, Tobacco Use Cessation, Alcohol & Drug Use, Nicotine Transdermal System
- Trial name
- NCT00218452
- Testing
- Lifestyle counseling
- Where
- 3 sites in United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Post Partum Depression
Effectiveness of Thinking Healthy Program for Prevention of Antenatal Depression
The trial is to evaluate the effect of an evidence-informed, depression focused early prenatal prevention intervention at six weeks' postpartum.
- Trial name
- PAD (NCT04663243)
- Testing
- Thinking healthy Program sessions designed for antenatal period
- Where
- Pakistan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of the Punjab
Gender Dysphoria
Gender Identity and Own Body Perception
This study will provide valuable information on the neurobiological underpinning of gender dysphoria (GD) and the effects of sex hormones, and promises to uncover functional or structural neural patterns that could predict…
- Trial name
- NCT04374708
- Testing
- fMRI
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Tobacco Use, Smoking Cessation
Ketamine and Motivational Enhancement Therapy for the Treatment of Tobacco Use Disorder
The purpose of the study is to examine whether an investigational medication called ketamine is able to improve treatment outcomes for tobacco use disorder when delivered in conjunction with brief motivational enhancement…
- Conditions
- Tobacco Use, Smoking Cessation, Nicotine Dependence
- Trial name
- NCT05796791
- Testing
- Ketamine Hydrochloride, Motivational enhancement therapy
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Alzheimer Disease
Evaluation of [123I] MNI-330 and SPECT as a Marker of Beta-amyloid Protein Deposition
The main objectives of this proposal are as follows: To assess the dynamic uptake and washout of 123-I MNI-330, a potential imaging biomarker for β-amyloid burden in brain, using single photon emission computed tomography (SPECT)…
- Trial name
- NCT00657813
- Testing
- MNI-330 as a brain SPECT tracer of Beta-Amyloid
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Institute for Neurodegenerative Disorders
Postmenopausal Period, Fatigue
The Effect of Progressive Relaxation Exercises on Sleep Quality and Fatigue in Postmenopausal Period
The population of the study will be postmenopausal women who applied to the KETEM unit of a hospital in western Turkey for examination. This study is a two-group randomized controlled study.
- Conditions
- Postmenopausal Period, Fatigue, Sleep Quality
- Trial name
- NCT05483413
- Testing
- progressive relaxation exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Marijuana Dependence
Hormones and Reduction in Co-users of Marijuana and Nicotine
The purpose of this study is to examine the role of progesterone (a naturally occurring hormone found in both men and women) on reducing marijuana use.
- Trial name
- NCT02579421
- Testing
- Progesterone
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Marijuana Dependence
Treatment of Marijuana Withdrawal Syndrome Using Escitalopram and Cognitive-Behavior Therapy
Recent studies have established the reliability, validity and time course of the cannabis withdrawal syndrome. This study will investigate the effects of combined treatment of Escitalopram with cognitive-behavior therapy in…
- Trial name
- NCT00598052
- Testing
- Escitalopram
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Cognitive Function, Dementia
MIND Diet and Cognitive Function in Middle-aged and Older Adults
A 12-month cluster-randomized controlled trial designed to test the effect of the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet education on the rate of cognitive change and several other secondary…
- Trial name
- NCT06417749
- Testing
- Control arm, Intervention arm
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
Claustrophobia
Premedication for Claustrophobic Patients for MRI Scan
Claustrophobia is an irrational fear of restriction and suffocation. It is a specific phobia, according to DSM 5. Claustrophobic patients may fear that restriction of their limbs will hinder their ability to move quickly towards…
- Trial name
- NCT05876117
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Salem Anaesthesia Pain Clinic
Menstrual Irregularity, Stress Related Disorder
Women's Menstruation During the Covid-19 Pandemic
The COVID-19 crisis has rapidly become the most significant public health crisis of our times. It has particularly impacted healthcare workers (HCW) due to the over-whelming of healthcare resources, as well as a critical absence…
- Conditions
- Menstrual Irregularity, Stress Related Disorder, COVID-19 Pneumonia, Fear
- Trial name
- NCT05197491
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Binge-Eating Disorder
eBEfree - an ICT Adaptation of BEfree
The eBEfree project aims at testing the effectiveness of an information and communication technology-based delivery version of BEfree in individuals with obesity and Binge Eating Disorder (BED).
- Trial name
- eBEfree (NCT04101032)
- Testing
- eBEfree
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Coimbra
Kinesiophobia
Impact of Kinesiophobia on Descending Corticospinal and Bulbospinal Projections
Fear of movement (kinesiophobia) is a phenomenon commonly observed in people suffering from chronic pain. The aims of this project are to better understand the neurophysiological basis of this phenomenon, in particular 1) the…
- Trial name
- EchoKinésio (NCT05161832)
- Testing
- Nocebo
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Autism Spectrum Disorder (ASD)
Expression Intensity Modulates Social Intention Understanding in ASD Children
Children watch videos of a single model playing with toys, judge whether the model desires a new toy based on observing the model's varying expression intensities, and form a judgment on whether the model intends to obtain a new…
- Trial name
- NCT07884032
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Anorexia Nervosa, Constitutional Leanness
Energy Intake, Exercise and Constitutional Leanness
The aim of this study will be to identify the physical and dietary profile of adult women presenting constitutional leanness (CL), comparatively with normal-weight peers and BMI-matched women with anorexia nervosa.
- Trial name
- Nutrilean (NCT03981432)
- Testing
- REST-Fixed, REST-AdLib, EX-AdLib
- Where
- France
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
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