Clinical trials: Psychiatric Illness
Major Depressive Disorder
Neuro-Cardiac-Guided Transcranial Magnetic Stimulation: Replication and Dose-response.
Autonomic regulation is disturbed in patients with major depressive disorder (MDD), indicated by a higher heart rate (HR) and lower heart rate variability (HRV).
- Trial name
- NCT03652597
- Testing
- Transcranial magnetic stimulation (TMS)
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Utrecht University
Mental Health Disorder, Social Isolation
Peer Support Intervention to Mitigate Social Isolation and Stigma of Adolescent Motherhood in Zimbabwe
A community-based peer support intervention for adolescent mothers aged 14-18 years in Harare, Zimbabwe was developed and tested in partnership with adolescent mothers, community health workers, and key community stakeholders.
- Conditions
- Mental Health Disorder, Social Isolation, Stigma, Social
- Trial name
- NCT05213182
- Testing
- Young Women of Today
- Where
- United States
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- West Chester University of Pennsylvania
Mental Disorder, Perinatal
Perinatal Mental Health Care in Switzerland
This qualitative study with quantitative elements examines the health care provided to women who suffered from mental disorder during pregnancy and / or in the first year after birth (i.e. during the perinatal phase).
- Conditions
- Mental Disorder, Perinatal, Depression, Anxiety Disorders
- Trial name
- MADRE (NCT04185896)
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bern University of Applied Sciences
Stigmatization, Depression
Impact of Video Presentations on Medical Students' Attitudes Toward Mental Illness
This is a randomized controlled trial examining the impact of videos on medical students' implicit and explicit attitudes and knowledge related to mental illness in Nepal.
- Conditions
- Stigmatization, Depression, Psychosis
- Trial name
- NCT03231761
- Testing
- Service user testimonial videos, mhGAP didactic video
- Where
- 2 sites in Nepal
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- George Washington University
Specific Learning Disability, Healthy (Controls)
Neurotransmitter Levels in Children With Specific Learning Disorder
The aim of this clinical trial was to measure how specific neurotransmitter levels in children with Specific Learning Disorder (SLD) change compared to controls.
- Trial name
- SLD (NCT07240142)
- Testing
- Blood Product, Elisa test
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Dilara Ulger Ozbek
Smoking Cessation, Tobacco Use Disorder
Effectiveness of the Nicotine Patch in Suppressing Nicotine Withdrawal Symptoms in Women Versus Men - 1
Women typically have a more difficult time quitting smoking than men. Little research has been done to understand the differences between men and women that may cause this distinction.
- Trial name
- NCT00218140
- Testing
- nicotine transdermal system
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Anxiety Disorders, Major Depressive Disorder
Acquisition and Analysis of Relationships Between Longitudinal Emotional Signals Produced by an Artificial Intelligence Algorithm and Self-questionnaires Used in the Psychiatric Follow-up of Patients With Mood and/or Anxiety Disorders: a Real-Environment Study.
The worldwide prevalence of anxiety and depression increased massively during the pandemic, with a 25% rise in the number of patients suffering from psychological distress.
- Trial name
- EMOACQ-1 (NCT05988840)
- Testing
- Acquisition and analysis of relationships between Longitudinal Emotional Signals produced by a software and Self-questionnaires.
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Emobot
Dementia, Alzheimers Disease
Establishment of a Bank of Biospecimens for Future Research on Age-related Cognitive Disorders
This study is collecting tissue specimens (blood, urine and saliva) from up to 1000 patients, with and without cognitive disorders, to store in the Bio Bank for future research.
- Trial name
- NCT00911690
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Corewell Health East
Mental Illness
Multimodal Psychotherapy Training for Chinese Medical Students
Providing evidence-based, well-designed psychotherapy teaching to train them to get a basic understanding of psychotherapy and to gain required skills for clinical practice would be fundamental to medical students, residency.
- Trial name
- NCT06258460
- Testing
- psychotherapy training program intervention, the wail-list control intervention
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Sir Run Run Shaw Hospital
Disability, Intellectual, Disability Psychological
The Role of Family and Individual Factors in Going Through Adolescence - Perspective of a Healthy Child.
The goal of this observational study is to investigate the specificity of the growing up process in young people with disabled siblings.
- Conditions
- Disability, Intellectual, Disability Psychological, Disability, Developmental, Diabetes
- Trial name
- NCT06156124
- Testing
- Psychological tests and psychosocial questionnaires
- Where
- Poland
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- University of Gdansk
Lewy Body Dementia (LBD), Alzheimer Dementia (AD)
Targeting Neuroinflammation as a Contributing Pathology in Alzheimer's Disease Dementia and Related Dementias
This study is being done to research the usefulness of PET/CT imaging for measuring brain inflammation and its relation to Alzheimer's Disease Dementia and related dementias.
- Trial name
- NCT04786223
- Testing
- C-11 ER-176, Blood Test
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Val Lowe
Autism Spectrum Disorder (ASD)
Internalized Symptoms in Adolescents With Autism Spectrum Disorder (ASD) and Typically Developing Adolescents : Gaining Insight Into Coping Strategies and the Psychological Processes Involved
Introduction: Adolescents with autism spectrum disorder (ASD) have more mental health problems than typically developping adolescents (without ASD).
- Trial name
- NCT07360223
- Testing
- Questionnaire and interview
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Healthy Subjects, Kleine-Levin Syndrome
Brain Scintigraphy in Normal Versus Kleine-Levin Syndrome Subjects
The investigators perform neuropsychological tests and brain scintigraphy in 30 healthy subjects. These results will be compared with data obtained out of episode in patients with Kleine-Levin syndrome (KLS).
- Trial name
- SCINTIK (NCT02337023)
- Testing
- Brain scintigraphy with injection of Neurolite® (ECD)
- Where
- France
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Postpartum Depression (PPD)
An Online Self-compassion Intervention for Anxiety and Depression in Fathers of Infants: A Feasibility Study
To investigate the feasibility, acceptability, and preliminary effectiveness of an online mindfulness and self-compassion intervention for the mental health in fathers experiencing paternal perinatal depression (PPD).
- Trial name
- NCT07077759
- Testing
- Online self-compassion intervention
- Where
- Hong Kong
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hong Kong Metropolitan University
Alzheimer Disease
Evaluation of [123I] AV94 and SPECT in Subjects With Alzheimer Disease in Comparison to Healthy Subjects
The main objectives of this proposal are as follows: To assess the dynamic uptake and washout of 123-I AV94, a potential imaging biomarker for β-amyloid burden in brain, using single photon emission computed tomography (SPECT) in…
- Trial name
- AV94 (NCT00605059)
- Testing
- [123I]AV94
- Where
- 2 sites in United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Institute for Neurodegenerative Disorders
Anxiety
Cognitive Anxiety Sensitivity Treatment for Suicide
The purpose of this study is to test the effectiveness and usability of a computer-based treatment for mood and anxiety relevant risk factors.
- Trial name
- CAST (NCT01947179)
- Testing
- Anxiety Risk Reduction
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Florida State University
Cognitive Impairment, Mild
Appropriate Compatibility of Propofol and Sevoflurane for Orthopaedic Surgery of Patients With MCI
According to the inclusion and exclusion criteria, elderly patients undergoing elective orthopedic surgery were randomly divided into four groups.
- Trial name
- MCI (NCT03165396)
- Testing
- Propofol, Sevoflurane
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Third Central Clinical College of Tianjin Medical University
Postpartum Depression, Infant Development
Social Circumstances, Parenting Techniques, and Infant Development
1. Investigators aim to assess a novel behavioral intervention (currently approved in Protocol #6285) behavioral intervention that promotes maternally-mediated behavioral changes in young infants to reduce the risk of postpartum…
- Conditions
- Postpartum Depression, Infant Development, Rhythm; Sleep
- Trial name
- NCT02121496
- Testing
- Resources for Postpartum Parenting
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Obsessive-Compulsive Disorder
Cognitive Training in Obsessive Compulsive Disorder
This unique study will allow us to observe the neural correlates associated with working memory in an obsessive compulsive disorder (OCD) paradigm.
- Trial name
- CTOCD (NCT02818088)
- Testing
- n-Back (Cognitive Training)
- Where
- South Africa
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Stellenbosch
Depressive Disorder, Major
Study Evalutating the Pharmacokinetics (PK) and Safety of a Single Dose of Desvenlafaxine Sustained Release (DVS SR)
To assess the initial pharmacokinetic profile of single doses of 25mg and 50 mg of DVS SR to healthy subjects.
- Trial name
- NCT00440427
- Testing
- Desvenlafaxine Sustained Release (DVS SR)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
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