Clinical trials: Psychiatric Illness
Autism Spectrum Disorder
Temporal Pole Transcranial Alternating Current Stimulation for Children With Autism Spectrum Disorder
The goal of this open-label randomized controlledl trial is to explore the safety and efficacy of conventional transcranial alternating current stimulation (tACS) and transcranial temporal interference stimulation (tTIS)…
- Trial name
- NCT07045584
- Testing
- Transcranial Alternating Current Stimulation, transcranial Temporal Interference Stimulation
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Fei Li
Substance Use Disorders
Online Cognitive Behavioural Therapy for Substance Use Disorder: The Impact of Peer Support
The purpose of this study is to evaluate the efficacy and cost-effectiveness of Breaking Free Online, in a comparison of outpatients seeking treatment for substance use disorder who receive standard care with group peer support…
- Trial name
- NCT05127733
- Testing
- Online Cognitive Behavioural Therapy, Individual Peer Support, Group Peer Support
- Where
- Canada
- Volunteers
- 198 people
- Sponsor
- Centre for Addiction and Mental Health
Attention Deficit Hyperactivity Disorder
A Study of Atomoxetine for Attention Deficit and Hyperactive/Impulsive Behaviour Problems in Children With ASD
The primary purpose of this study is to evaluate the tolerability and effectiveness of atomoxetine in the treatment of attention problems, hyperactivity, and impulsivity in children with ASD, and secondarily, to evaluate the…
- Trial name
- NCT00485849
- Testing
- Atomoxetine Hydrochloride
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- Eli Lilly and Company
Erectile Dysfunction
A Study in Erectile Dysfunction
The purpose of this study is to determine the day of onset of efficacy of tadalafil dosed once-a-day.
- Trial name
- NCT00833638
- Testing
- Tadalafil
- Where
- United States
- Volunteers
- 372 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Exercise Intervention
Exercise Intervention on Conflict Monitoring in Children With Attention-deficit Hyperactivity Disorder
The study mainly investigates the effect of high-intensity interval training on conflict monitoring in children with ADHD by using event-related potential and sLORETA techniques.
- Trial name
- ADHD (NCT04112758)
- Testing
- High-intensity interval training
- Where
- Taiwan
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Alcohol Drinking, Alcohol-Related Disorders
Feasibility and Potential Effectiveness of a Case Management Intervention for Alcohol Use-Related Problems in Frequent Users of an Emergency Department: a Pilot Study
Alcohol use and its consequences represent an important public health problem. As well as alcohol dependence, hazardous drinking also contributes to a high burden in terms of morbidity and mortality.
- Trial name
- MALUA_Freq_P (NCT04938258)
- Testing
- Intensive Case Management
- Where
- Spain
- Volunteers
- 5 people
- Sponsor
- Hospital Clinic of Barcelona
Pain, Delirium
Longitudinal Cohort Study - for the Treatment of Acute Postoperative Pain and Postoperative Delirium, Postoperative Cognitive Dysfunctions, and Chronic Pain.
Adequate pain therapy is important aspect of perioperative care. Sequelae of inadequate pain management are patient dissatisfaction, post-operative nausea and vomiting (PONV), inadequate nutrition, lack of mobilization, and an…
- Conditions
- Pain, Delirium, Postoperative Cognitive Dysfunction
- Trial name
- NCT03133858
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Charite University, Berlin, Germany
Schizophrenia, Schizoaffective Disorder
Safety and PK Trial With Injectable ZX003 (Risperidone-SABER®) Compared to Risperdal® Consta® in Stable Schizophrenia
This is an open-label, multiple dose, PK and safety study in patients with chronic, stable schizophrenia or schizoaffective disorder.
- Trial name
- NCT02411526
- Testing
- ZX003 (Risperidone-SABER®), Risperdal Consta, Oral Risperidone
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Zogenix, Inc.
Common Mental Disorder
Sustainable and Healthy Return-to-Work Program - PRATICAdr 2.0
This study aims to assess the effectiveness of PRATICAdr 2.0, a web application facilitated by a Return-to-Work Coordinator (RTW-C), with a focus on reducing sick leave duration and preventing relapse in individuals with CMDs.
- Trial name
- PRATICAdr (NCT06397326)
- Testing
- Return to work coordinator + PRATICAdr 2.0, Return to work coordinator only
- Where
- Canada
- Volunteers
- 49 people
- Sponsor
- Université du Québec a Montréal
Smoking Cessation, Nicotine Dependence
Study Assessing Efficacy and Safety of NFL-101 on Reduction of Reinforcing Properties of Cigarettes (PRECESTO)
PRECESTO is a randomized, double-blind, cross-over trial on 34 smokers who do not want to stop smoking and get high satisfaction from smoking.
- Trial name
- PRECESTO (NCT06091826)
- Testing
- NFL-101
- Where
- France
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- NFL Biosciences SAS
Postoperative Delirium
Postoperative Delirium: EEG Markers of Sleep and Wakefulness
Postoperative delirium is a condition in which patients develop temporary difficulties in maintaining attention and thinking clearly. These new problems can appear after surgery and change throughout the day.
- Trial name
- NCT03291626
- Where
- United States
- Volunteers
- 234 people
- Sponsor
- Washington University School of Medicine
Treatment Resistant Depression
Working Mechanisms and Effectiveness of IV Ketamine-assisted Psychotherapy on Depression in TRD Clients
Ketamine-Assisted Psychotherapy (KAP) is an innovative treatment that combines intravenous ketamine with psychotherapy in a carefully monitored clinical setting.
- Trial name
- NCT07706478
- Where
- Netherlands
- Volunteers
- 120 people
- Sponsor
- Senz
Moderate Depression, Major Depressive Disorder
The Dosage Effect of pBFS Guided rTMS Treatment for MDD
The investigators aim to find the optimal dosage of the pBFS-guided rTMS treatment for patients with moderate to severe depression.
- Conditions
- Moderate Depression, Major Depressive Disorder, Severe Depression
- Trial name
- NCT05842278
- Testing
- 4 session rTMS, 6 session rTMS, 8 session rTMS
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Changping Laboratory
Substance-Related Disorders, Mood Disorders
Behavioral Activation for Heroin Use in China: A Randomized Controlled Trial
This was a single-site two-arm parallel-group trial conducted in a Methadone Maintenance Treatment (MMT) Clinic that provides medication service for 254 heroin users in Wuhan, China.
- Conditions
- Substance-Related Disorders, Mood Disorders, Behavioral Activation Treatment, Mental Disorders
- Trial name
- NCT03705143
- Testing
- Treatment as usual, Chinese translated LETS ACT
- Where
- China
- Volunteers
- 90 people
- Sponsor
- University of North Carolina, Chapel Hill
Infusion of Ketamine in Severe Borderline Personality Disorder, Borderline Personality Disorder (BPD)
Ketamine Infusion for Symptomatic Improvement in Severe Borderline Personality Disorder
The main objective of this pilot study is to evaluate at D9 the evolution of BPD symptoms' intensity(scale BSL-23) in severe BPD patients, after two Ketamine infusions (0.5mg/kg at H0 and H24).
- Trial name
- BorderKET (NCT07099534)
- Testing
- IV Ketamine (0.5 mg/kg) Infusion - Two Doses Administered 24 Hours Apart for Severe Borderline Personality Disorder
- Where
- France
- Volunteers
- 38 people
- Sponsor
- University Hospital, Toulouse
Bipolar Disorder
A Six-week Flexible Dose Study Evaluating the Efficacy and Safety of Geodon in Patients With Bipolar I Depression.
This is a 6-week trial that evaluates the efficacy and safety of Geodon (ziprasidone) in outpatient subjects ages 18 and older with Bipolar Disorder type I, depressed.
- Trial name
- NCT00282464
- Testing
- Geodon (Ziprasidone)
- Where
- 43 sites in United States
- Volunteers
- 392 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Trauma, Posttraumatic Stress Disorder
Tachikawa Project for Prevention of Posttraumatic Stress Disorder With Polyunsaturated Fatty Acid (TPOP): TPOP-02 Study
The purpose of this study is to evaluate efficacy and safety of Polyunsaturated Fatty Acid for the prevention of Posttraumatic Stress Disorder (PTSD) in patients with accidental injuries.
- Trial name
- NCT00671099
- Testing
- Omega-3 Polyunsaturated Fatty Acid
- Where
- Japan
- Volunteers
- 110 people
- Sponsor
- Japan Science and Technology Agency
Schizophrenia Spectrum and Other Psychotic Disorders, Mental Disorders, Severe
Family Psychoeducation for Adults With Psychotic Disorders in Tanzania
The goal of this study is to pilot test a culturally tailored Family Psychoeducation model (KUPAA) for adults with psychotic disorders and their relatives that is appropriate for cultural settings inclusive of both traditional…
- Trial name
- NCT04013932
- Testing
- KUPAA Intervention Group (Culturally Tailored Family Psychoeducation)
- Where
- 2 sites in Tanzania
- Volunteers
- 66 people
- Sponsor
- Duke University
Parkinson Disease, Mild Cognitive Impairment
Parkinson's Disease With Mild Cognitive Impairment Treated With Nicotinic Agonist Drug
To test for the first time the potential of a nicotinic agonist on cognitive symptoms in people with mild cognitive impairment (MCI) in Parkinson's disease (PD), referred to as PD-MCI.
- Trial name
- PD-MIND (NCT04810104)
- Testing
- AZD0328
- Sponsor
- King's College London
Schizophrenia
C-Cog in Early Course Schizophrenia Study
The purpose of this study is to examine the role of clinical stability in functional recovery. in first episode schizophrenia.
- Trial name
- NCT05662306
- Testing
- Aripiprazole Lauroxil, Computerized cognitive and functional skills training
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Miami
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