Clinical trials: Psychiatric Illness
Narcotic Abuse
Aprepitant Effects on Oxycodone Response
Addressing the issue of opioid dependence and tolerance has public health implications for the treatment of opioid abuse (both heroin as well as pharmaceutical opioids) and for the treatment of pain.
- Trial name
- NCT00999544
- Testing
- Aprepitant 0mg, Aprepitant 40mg, Aprepitant 200mg
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Sharon Walsh
HIV Disease, Bipolar Disorder
Texting to Improve Adherence in HIV+ With Bipolar Disorder
Adherence to combination antiretroviral therapy (ART) is critical for successful HIV viral suppression. Nonadherence to ART poses several potentially serious health consequences, including higher viral loads, faster progression…
- Trial name
- iTAB (NCT02090634)
- Testing
- Psychoeducation, individualized Texting for Adherence Building (iTAB)
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- University of California, San Diego
Right Hemispheric Stroke
Functional Connectivity and Predictors of Affective Aprosodia Intervention in Subacute Right Hemisphere Stroke
This study is an investigation of a behavioral speech and language treatment for emotional prosody recognition and production deficits in subacute right hemisphere stroke.
- Trial name
- NCT04575909
- Testing
- Aprosodia Intervention, No-Intervention
- Where
- United States
- Sponsor
- Johns Hopkins University
Alzheimer s Disease, Vascular Dementia
Predictors of Emergency Department Use in Frail Patients
When admitted to the emergency department (ED), elderly non-autonomous patients show high risk of adverse health outcomes. The prompt identification of ED use risk factors in such population is hence needed.
- Conditions
- Alzheimer s Disease, Vascular Dementia, Frailty, Elderly
- Trial name
- THE-Spoke 10 (NCT07259499)
- Testing
- Plasma phosphorylated Tau 181
- Where
- Italy
- Volunteers
- 110 people
- Sponsor
- University of Pisa
Posttraumatic Stress Disorder
Stepped Care for Young Children After Trauma
The aim of this R34 study is to develop and test the feasibility of a Stepped Care intervention for young children with Posttraumatic Stress Disorder (PTSD).
- Trial name
- NCT01603563
- Testing
- Stepped Care TF-CBT, Standard TF-CBT
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of South Florida
Dyssomnias
A Multicomponent Intervention for Prevention and Treatment of Sleep Disturbances in a Psychiatric Intensive Care Unit
Hospitalized adult patients suffer from sleep deprivation, which has been associated with multiple negative consequences, both in short and in the long term.
- Trial name
- SUEÑA-SM (NCT04995263)
- Testing
- Sueña component 1: Sleep Hygiene Promotion, Sueña component 2: Periodic Anxiety and Pain Screening, Sueña component 3: Hypnotics and Caffeine Regulation
- Where
- Chile
- Volunteers
- 120 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Genito-Pelvic Pain/Penetration Disorder, Dyspareunia
VIBRating vs Traditional Therapy for Treatment of ENTry Dyspareunia
The goal of this randomized controlled trial is to determine whether the use of a novel vibrating pelvic floor therapeutic device ("Kiwi") improves sexual function in sexually active women aged 18 and older with genito-pelvic…
- Conditions
- Genito-Pelvic Pain/Penetration Disorder, Dyspareunia, Vaginismus, Pelvic Pain
- Trial name
- VIBRENT (NCT06840314)
- Testing
- Pelvic floor therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Medstar Health Research Institute
Anxiety, Comfort
The Effect of Video Streaming With Virtual Reality Before Coronary Angiography
This study was planned as a randomized controlled experimental study to examine the effects of virtual reality video on anxiety, comfort and patient satisfaction before coronary angiography.
- Conditions
- Anxiety, Comfort, Patient Satisfaction
- Trial name
- NCT06458647
- Testing
- Video Streaming with Virtual Reality
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- TC Erciyes University
Restless Legs Syndrome
XP13512 vs. Placebo in Patients With Restless Legs Syndrome.
The primary objective of this trial is to assess the efficacy of XP13512 taken once daily compared to placebo for the treatment of patients suffering from Restless Legs Syndrome (RLS).
- Trial name
- NCT00365352
- Testing
- XP13512 600MG, XP13512 1200MG
- Volunteers
- 325 people
- Sponsor
- XenoPort, Inc.
Depression, Anxiety
A Randomized Controlled Trial of a VR Social Music-Movement Exergame for Depression and Anxiety in Young Adults
This randomized controlled trial aims to evaluate the effectiveness of a virtual reality (VR) music-movement exergaming intervention for improving social connectedness and psychological well-being among young adults.
- Trial name
- VR-MOVE (NCT07482852)
- Testing
- VR social musical exergame, VR solo musical exergame, Waitlist control
- Volunteers
- 130 people
- Sponsor
- Hunan University of Traditional Chinese Medicine
Vasculogenic Erectile Dysfunction
Low Intensity Extracorporeal Shockwave Therapy (LI-ESWT) by 'Renova' for Patients With Erectile Dysfunction
This is a prospective, randomized, double-blind clinical study for assessing the safety and efficacy of the treatments performed with Renova (LI-ESWT) on symptomatic ED patients.
- Trial name
- NCT01814852
- Testing
- Shockwave system
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Initia
Schizophrenia, Major Depressive Disorder
DIMES - DIgital MEdicine Study for Adults With Schizophrenia, Bipolar I Disorder, or Major Depression Currently Using Aripiprazole
This is a 12 month, pragmatic trial designed to assess the differences in a digital medicine system (DMS)- ABILIFY MYCITE (Aripiprazole tablets with sensor)- measuring adherence versus treatment as usual (TAU) for adult patients…
- Conditions
- Schizophrenia, Major Depressive Disorder, Bi-Polar Disorder, Schizo Affective Disorder
- Trial name
- DIMES (NCT03881449)
- Testing
- ABILIFY MYCITE
- Where
- 2 sites in United States
- Volunteers
- 46 people
- Sponsor
- Durham VA Medical Center
Bipolar Disorder, Manic, Bipolar Disorder I
Accelerated Theta Burst Stimulation for Inpatients With Bipolar Disorder
This study evaluates the efficacy of an accelerated schedule of theta-burst stimulation for treating manic episodes in bipolar disorder. In this open-label study, all participants will receive accelerated theta-burst stimulation.
- Trial name
- NCT04058249
- Testing
- Accelerated intermittent theta-burst stimulation over right DLPFC
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Stanford University
Chronic Pain, Opioid Use Disorder
Virtual Reality for Chronic Pain and Opioid Use Disorder Pilot
This is a pilot feasibility study of a virtual reality device for patients with co-morbid chronic pain and opioid use disorder.
- Trial name
- NCT05546749
- Testing
- RelieVRx
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Albert Einstein College of Medicine
HIV Infections, Pregnancy Related
Adaptation of an Intervention Addressing Barriers to PrEP Use Among Pregnant Women in Zimbabwe
The purpose of this study is to develop a multi-level PrEP adherence and persistence intervention as an adaptation of the TENDAI ('grateful' in Shona) program, a problem-solving approach to reduce depression and increase HIV…
- Conditions
- HIV Infections, Pregnancy Related, Depression, Anxiety
- Trial name
- TENDAI4PrEP (NCT06226155)
- Testing
- TENDAI4PrEP, Enhanced treatment as usual
- Where
- Zimbabwe
- Volunteers
- 165 people
- Sponsor
- Massachusetts General Hospital
Depressive Disorder, Depression
A Study of Flexible-dose Brexpiprazole as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder, the Delphinus Trial
To compare the efficacy of brexpiprazole (flexible dose) with placebo as adjunctive therapy to an assigned open label antidepressant therapy (ADT) in the proposed subject population with MDD.
- Conditions
- Depressive Disorder, Depression, Depressive Disorder, Major, Mood Disorders
- Trial name
- NCT01727726
- Testing
- Brexpiprazole, Seroquel XR
- Where
- 76 sites in United States, Canada and 5 more
- Volunteers
- 2,182 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Depression
Effectiveness of Group Interpersonal Psychotherapy in Treating Women With Prenatal Depression
This study will evaluate the effectiveness of group interpersonal psychotherapy for preventing postpartum depression in pregnant women with depression and for improving healthy outcomes in their babies.
- Trial name
- NCT00633178
- Testing
- Group interpersonal therapy (IPT), Treatment as usual (TAU)
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Alzheimer s Disease, Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease
NON-INVASIVE BRAIN STIMULATION FOR MEMORY LOSS IN EARLY ALZHEIMER'S DISEASE
The goal of this clinical trial is to learn if repetitive transcranial magnetic stimulation (rTMS), a non-invasive form of brain stimulation, can improve short-term memory in people with early Alzheimer's disease (AD).
- Conditions
- Alzheimer s Disease, Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease, Mild Dementia
- Trial name
- NCT07667478
- Testing
- repetitive transcranial magnetic stimulation (rTMS)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Chi-Ying (Roy) Lin
Schizophrenia
A Study of Long-acting Injectable Risperidone in the Treatment of Patients With Schizophrenia or Schizoaffective Disorder
The purpose of this study is to document the long-term safety and tolerability of risperidone, formulated as a long-acting injectable, in the treatment of patients with schizophrenia or schizoaffective disorder; in addition, to…
- Trial name
- NCT00210691
- Testing
- Risperidone
- Volunteers
- 273 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Dementia, Alzheimer's Disease
The Relationship Between Risperdal Treatment and Quality of Life in Patients With Alzheimer's Disease and Behavioural and Psychological Symptoms of Dementia (BPSD)
To evaluate the relationship between Risperidone Treatment, Treatment Discontinuation Rate, and Quality of Life of patients with Alzheimer's Disease and BPSD.
- Trial name
- NCT00626613
- Testing
- Risperdal,reminyl
- Where
- Taiwan
- Volunteers
- healthy volunteers welcome
- Sponsor
- Jinan Mental Hospital
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