Clinical trials: Psychiatric Illness
Depression, Depressive Symptoms
Does a Novel Intervention Targeting Derailment Decrease Depressive Symptoms?
The goal of this clinical trial is to explore the efficacy of a reflective journaling intervention-"Me Through Time"- in decreasing levels of derailment, and its impact on downstream depressive symptoms.
- Conditions
- Depression, Depressive Symptoms, Derailment, Anxiety
- Trial name
- NCT06265701
- Testing
- Derailment-Focused Reflective Journaling, Everyday Tasks Reflective Journaling
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Cornell University
22q13 Deletion Syndrome, Phelan-McDermid Syndrome
Clinical Trial in 22q13 Deletion Syndrome(Phelan-McDermid Syndrome)
The purpose of this study is to pilot the use of Insulin-Like Growth Factor-1 (IGF-1) treatment in 22q13 Deletion Syndrome (Phelan-McDermid Syndrome) caused by SHANK3 gene deficiency in order to evaluate safety, tolerability, and…
- Trial name
- NCT01525901
- Testing
- Insulin-Like Growth Factor-1 (IGF-1), Normal saline
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Depression
Collabri Flex - Effect of Collaborative Care for People With Depression in General Practice
The aim of the study Collabri Flex is to: Develop a Danish model for collaborative care for patients with depression in general practice, based on past experience gained in the Collabri Project.
- Trial name
- Collabri Flex (NCT03113201)
- Testing
- Collaborative care, Consultations-Liaison
- Where
- Denmark
- Volunteers
- 389 people
- Sponsor
- Amager Hospital
Major Depression, Dysthymia
Are Two Antidepressants a Good Initial Treatment for Depression?
Relatively drug naive patients will receive two antidepressant medications as initial treatment.
- Conditions
- Major Depression, Dysthymia, Depression NOS
- Trial name
- NCT00296712
- Testing
- escitalopram + bupropion
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- New York State Psychiatric Institute
Communication Disabilities
Improving Communication and Healthcare Outcomes for Patients With Communication Disabilities
In the United States, 14% of all adults report a speech, language, voice, and/or hearing disability (collectively known as communication disabilities, CD).
- Trial name
- NCT04697212
- Testing
- Healthcare team- + patient-directed intervention, Healthcare team-directed intervention
- Where
- 5 sites in United States
- Volunteers
- 687 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Insomnia, Insomnia Chronic
SHADES Mechanistic Trial
Cardiovascular disease (CVD) is common, deadly, and costly, and adults with insomnia represent a large group of people at elevated risk of developing CVD in the future.
- Conditions
- Insomnia, Insomnia Chronic, Insomnia, Primary, Sleep Disturbance
- Trial name
- SHADES (NCT06041581)
- Testing
- Sleep Healthy Using The Internet (SHUTi), Telephonic CBT-I, Face-to-Face CBT-I
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Indiana University
Attention-Deficit/Hyperactivity Disorder
Comparison of Lisdexamfetamine Dimesylate With Atomoxetine HCl in Attention-Deficit/Hyperactivity Disorder (ADHD) Subjects With an Inadequate Response to Methylphenidate
This study will evaluate how long it takes for ADHD symptoms to improve in subjects who are judged by the Investigator to have had an inadequate response to methylphenidate therapy.
- Trial name
- NCT01106430
- Testing
- Lisdexamfetamine Dimesylate, Atomoxetine Hydrochloride
- Where
- 64 sites in United States, Belgium and 8 more
- Volunteers
- 267 people
- Sponsor
- Shire
Moderate Alzheimer's Disease
Efficacy Study of a ZT-1 Implant in Patients Suffering From Alzheimer's Disease
Alzheimer's disease is characterised by memory loss and difficulties with thinking. These problems may be due to a deficiency in a brain chemical called acetylcholine. Acetylcholine helps transmit messages between nerve cells.
- Trial name
- BRAINz (NCT00423228)
- Testing
- ZT-1, Donepezil
- Where
- 28 sites in Australia, Canada and 1 more
- Volunteers
- 228 people
- Sponsor
- Debiopharm International SA
Generalized Anxiety Disorder
A Study to Asses Safety and Tolerability of ITI-1284 Given Alone or as an Additional Treatment in Participants With Generalized Anxiety Disorder (GAD)
The purpose of this study is to assess how safe ITI-1284 is and how well it can be tolerated in long-term, when given alone or with other medicines, in participants with generalized anxiety disorder (GAD) who have not responded…
- Trial name
- NCT07807865
- Testing
- ITI-1284
- Where
- 3 sites in United States
- Volunteers
- 900 people
- Sponsor
- Intra-Cellular Therapies, Inc.
Relative Energy Deficiency in Sport
Evaluation of a Practice-oriented Recovery Program for Female Endurance Athletes With Relative Energy Deficiency
The aim of this study is to develop, implement and evaluate the effects of a 16 week practice orientated sports nutrition education and counselling program aiming to improve energy availability and to investigate the effects on…
- Trial name
- NCT04959565
- Testing
- Nutritional behavioral intervention
- Where
- 4 sites in Germany, Ireland and 2 more
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Monica Klungland Torstveit
Alzheimer's Disease
Telmisartan vs. Perindopril in Mild-Moderate Alzheimer's Disease Patients
To conduct a proof of concept study in patients with mild to moderate Alzheimer's Disease in order to determine if there is less global brain atrophy over one year, as measured by ventricular enlargement as a primary outcome…
- Trial name
- SARTAN-AD (NCT02085265)
- Testing
- Perindopril, Telmisartan
- Where
- 10 sites in Canada
- Volunteers
- 23 people
- Sponsor
- Sunnybrook Health Sciences Centre
Huntington Disease
Time-Restricted Eating in Huntington's Disease: A Clinical Pilot Study
This trial examines whether 12 weeks of time-restricted eating (TRE), otherwise known as intermittent fasting, appears safe and feasible in persons with early-stage Huntington's disease (HD).
- Trial name
- TREHD (NCT06490367)
- Testing
- Time-Restricted Eating Diet
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Oregon Health and Science University
Diabetes, Dementia
Enhanced Quality in Primary Care for Elders With Diabetes and Dementia
The purpose of this study is to develop and test a care quality improvement intervention featuring use of consensus decisional guidance for the medical management of diabetes (DM) in patients with Alzheimer's disease and related…
- Conditions
- Diabetes, Dementia, Alzheimer Disease
- Trial name
- EQUIPED-ADRD (NCT03723707)
- Testing
- EQUIPED-ADRD Intervention, Control (CON)
- Where
- United States
- Volunteers
- 355 people
- Sponsor
- NYU Langone Health
Schizophrenia
Safety, Pharmacokinetics and Efficacy Study of MP-214 in Patients With Schizophrenia
The purpose of this study is to assess the safety, pharmacokinetics and efficacy of 3 fixed doses of MP-214 orally administered once daily to patients with schizophrenia.
- Trial name
- NCT00862992
- Testing
- Cariprazine 3 mg, Cariprazine 6 mg, Cariprazine 12.5 mg
- Where
- Japan
- Volunteers
- 34 people
- Sponsor
- Tanabe Pharma Corporation
Depressive Disorder, Major
Abilify as an Adjunctive Treatment for Refractory Depression
This is a study of the effectiveness of adding Abilify (aripiprazole), an atypical antipsychotic medication, to ongoing selective serotonin reuptake inhibitor (SSRI) antidepressant treatment for depressed outpatients who are not…
- Trial name
- NCT00220636
- Testing
- Aripiprazole
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Loneliness, Cognitive Impairment
The Presence of Humanoid Robot With Older Adults at Homes
Background Older adults experience significant physical, cognitive and environmental losses in their later life. Self-supported 'aging-in-place' has benefits for mental health and the quality of life for older people.
- Conditions
- Loneliness, Cognitive Impairment, Depression, Self Efficacy
- Trial name
- NCT06487611
- Testing
- A humanoid social robot
- Where
- Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Substance Use, Healthy Subjects
Abuse Potential and Human Pharmacology of Methylone
The purposes of the study are 1) To assess the abuse potential of methylone after controlled administration of a single oral dose of methylone 2) to evaluate subjective and physiological effects of methylone 3) to determine the…
- Trial name
- METI/FIS/1 (NCT05488171)
- Testing
- Methylone, 3,4-methylenedioxymethamphetamine
- Where
- Spain
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Germans Trias i Pujol Hospital
Cognitive Impairment
RIVastigmine In Vascular cognitivE Impairment
The study is a 24-week prospective, double blind, randomized, placebo-controlled pilot study of 9 mg / day Rivastigmine in patients with Vascular Cognitive Impairment Not Dementia (CIND) to evaluate efficacy, safety and…
- Trial name
- RIVIVE (NCT00669344)
- Testing
- Exelon (rivastigmine)
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- Singapore General Hospital
Schizophrenia and Schizoaffective Disorder
A Study of Aripiprazole in Patients With Schizophrenia in General Psychiatric Practices
The purpose of this clinical research study is to evaluate the overall effectiveness of 8 week of aripiprazole treatment.
- Trial name
- NCT00292409
- Testing
- Aripiprazole
- Volunteers
- 400 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Dementia, Alzheimer Disease
Self-Directed Online Training for Chinese Caregivers
The proposed project seeks to develop an online self-directed learning (SDL) intervention program that seeks to improve caregiving and self-care skills among ethnic Chinese dementia caregivers.
- Trial name
- NCT03308032
- Testing
- Intervention, Control
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Environment and Health Group, Inc.
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.