Clinical trials: Psychiatric Problem, open to volunteers
Non-Small Cell Lung Cancer, Advanced Lung Cancer
Nurse-Led Caregiver Support for Older Adults With Advanced Lung Cancer
This two-phase study aims to examine the current status of older adults with newly diagnosed locally advanced or advanced non-small cell lung cancer and their primary family caregivers, and to evaluate the effects of the…
- Conditions
- Non-Small Cell Lung Cancer, Advanced Lung Cancer, Caregiver Burden, Resource Utilization
- Trial name
- ICSM (NCT07708870)
- Testing
- Integrating Nurse-Led and Resource Utilization-Based Caregiver Support Model, Oncology Case Manager Care and Usual Care
- Where
- 2 sites in Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Breast Cancer, Psychological Distress
The Validation of ICBT Clinical Trial: Disease Stress Adjustment in Breast Cancer Patients
Breast cancer and its treatment can cause ongoing emotional distress, including anxiety, depressive symptoms, stress-related reactions, and difficulties adjusting to life after treatment.
- Trial name
- ICBT-TW-2 (NCT07835698)
- Testing
- Internet-Based Cognitive Behavioral Therapy Program for Breast Cancer Survivors, Treatment as Usual (TAU)
- Volunteers
- 100 people
- Sponsor
- National Health Research Institutes, Taiwan
Psychological Distress
Existential Group Treatment for Older Adults (75+) With Psychological Distress in Primary Care
Symptoms of depression and anxiety are common in older adults, and high suicide rates are observed in this age group in Sweden, as in many countries around the globe.
- Trial name
- NCT05503485
- Testing
- Existential group treatment, Supportive telephone calls
- Where
- 7 sites in Sweden
- Volunteers
- 140 people
- Sponsor
- Göteborg University
Demographic Data, History of Medical and Mental Health
VISN 19 MIRECC Research Database
The VISN 19 MIRECC is involved in research concerned with suicide prevention in high risk populations (e.g., history of traumatic brain injury, post-traumatic stress disorder); Recruitment for future studies will continue with a…
- Conditions
- Demographic Data, History of Medical and Mental Health, History of Combat Experience, History of Suicide
- Trial name
- Repository (NCT01334476)
- Where
- 2 sites in United States
- Volunteers
- 5,000 people
- Sponsor
- VA Eastern Colorado Health Care System
Alzheimer's Disease (AD), Dementia
Negotiation Training for Family Caregivers of People With Alzheimer's Disease
Family caregivers of people living with Alzheimer's disease and related dementias often experience conflicts and communication challenges when coordinating care, making decisions, and interacting with family members and…
- Conditions
- Alzheimer's Disease (AD), Dementia, Cognitive Impairment
- Trial name
- NCT07859540
- Testing
- NegotiAge, PlanYourLifespan
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Depression - Major Depressive Disorder, Depression Anxiety Disorder
Evaluating the Effectiveness and Acceptability of a GPT-4o and RAG-Based Voice Chatbot for Depression Screening Using PHQ-9
This study aims to assess the feasibility and acceptability of a voice-based chatbot, powered by GPT-4o and Retrieval-Augmented Generation (RAG), for conducting depression screening using the Patient Health Questionnaire-9…
- Trial name
- GPT4-RAG-PHQ (NCT06801925)
- Testing
- GPT-4o and RAG Voice Chatbot for PHQ-9 Screening
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University College, London
Adult Caregivers of Individuals With TSC, Tuberous Sclerosis Complex (TSC)
TANDem-2: Closing the Gap to Interventions for TAND
The goal of this pilot study is to determine the feasibility, acceptability and impact of a brief behavioral intervention - the "Well-Beans for Caregivers" program, for adult caregivers of individuals with tuberous sclerosis…
- Trial name
- TANDem-2 (NCT06879665)
- Testing
- Well-Beans for Caregivers Program
- Where
- 2 sites in United States, Australia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Alzheimer Disease, Caregiver Burden
Swallowing Impairments in Adults With and Without Alzheimer's Disease
This research study is investigating whether people with Alzheimer's disease (AD) experience more changes to swallowing than their healthy age-matched peers.
- Conditions
- Alzheimer Disease, Caregiver Burden, Healthy Aging, Dysphagia
- Trial name
- NCT06678100
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Oncology, Caregiver Burden
Assessment and Prevention of Caregiver Burden in Oncology
The goal of this randomized, open and controlled supportive care study is to see if we can reduce the burden on the caregiver by offering the caregiver systematic and regular support from the nurse (APN, nurse coordinator in…
- Trial name
- PREPAC-01 (NCT05750836)
- Testing
- Specific nursing support, Non-specific nursing support
- Where
- 5 sites in France
- Volunteers
- 250 people
- Sponsor
- Institut Cancerologie de l'Ouest
Breast Neoplasms, Mastectomy; Lymphedema
Self-Affirmation Intervention After Mastectomy
This randomized controlled trial aims to evaluate the effect of a structured self-affirmation intervention on pain, depression, anxiety, and stress levels in patients undergoing mastectomy.
- Conditions
- Breast Neoplasms, Mastectomy; Lymphedema, Pain, Depression
- Trial name
- NCT07355244
- Testing
- Positive Self-Affirmation Audio with Calming Background Sounds
- Volunteers
- 42 people
- Sponsor
- Muş Alparslan University
Bone Sarcomas, Financial Toxicity
Financial Toxicity in Patients With Resected Soft Tissue and Bone Sarcomas
To learn about the financial stress patients undergoing surgery to treat orthopedic cancer experience because of the costs of cancer care, and to learn about the effects of financial stress on participants quality of life.
- Trial name
- NCT07215611
- Testing
- data collection
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- M.D. Anderson Cancer Center
Behavior
Acute Effect of Aerobic Exercise on Cardiovascular Reactivity During a Mental Stress Test in Teachers
This study will investigate the acute effect of a single session of moderate-intensity aerobic exercise on blood pressure responses to mental stress in teachers.
- Trial name
- NCT07911865
- Testing
- Acute Exercise, Control
- Where
- Brazil
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Federal University of Mato Grosso
Qigong
Understanding the Psychological Benefits and Neurophysiological Mechanisms of Qigong in Older Adults
One goal of the study is to evaluate the efficacy of qigong to alleviate depressive symptoms and enhance cognitive function in comparison to mindfulness-based intervention, physical exercise, and waitlist control.
- Trial name
- NCT06952166
- Testing
- Qigong (Baduanjin), Mindfulness-based intervention, Physical exercise
- Where
- Hong Kong
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Delirium, Intensive Care Unit Delirium
Family-partnered Delirium Prevention, Detection, and Management in the ICU
Almost half of critically ill patients experience delirium. Delirium is associated with impaired cognition, mortality, and increased healthcare costs.
- Conditions
- Delirium, Intensive Care Unit Delirium, Post Intensive Care Unit Syndrome, Post Intensive Care Unit Syndrome Family
- Trial name
- ACTIVATE (NCT07896356)
- Testing
- Standard of Care, Delirium Education, Prevention, and Management
- Where
- Canada
- Volunteers
- 1,344 people
- Sponsor
- University of Calgary
Gender Incongruence
Transgender In Transition
Prospective trial in gender dysphoric patients who undergo gender-affirming hormone therapy, aiming to investigate psychological, biological and behavioural consequences of hormonal therapy.
- Trial name
- TRANSIT (NCT04028219)
- Testing
- Online surveys
- Where
- 5 sites in Germany, Switzerland
- Volunteers
- 750 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Erectile Dysfunction, Impotentia Erigendi
External Device for Erectile Dysfunction (3D-Erect)
The aim of this clinical trial is to test the safety and feasibility of a non-invasive 3D-printed external penile device to achieve successful and satisfactory sexual intercourse in men with erectile dysfunction (ED).
- Trial name
- 3D-Erect (NCT04624126)
- Testing
- 3D-Erect
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Stanford University
Progressing Stroke
Effect of ınformatıon to caregıvers of Stroke patıents wıth Percutaneous endoscopıc Gastrostomy
Stroke is one of the serious neurological disorders that occur due to decreased blood flow to a certain part of the brain due to vascular injuries.
- Trial name
- NCT06896058
- Testing
- Written and verbal training given to caregivers
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Emotional Processing and Cognitive Function in Perimenopausal Women Experiencing Cognitive Perturbations, Perimenopause
Probiotic Intake and Perimenopausal Psychological Assessments
Recent evidence suggests multi-strain probiotics containing Lactobacillus rhamnosus and Bifidobacterium longum have been found to enhance emotional processing and reduce salience to negative cues in studies involving people with…
- Conditions
- Emotional Processing and Cognitive Function in Perimenopausal Women Experiencing Cognitive Perturbations, Perimenopause, Perimenopause-Related Depression, Perimenopausal Women
- Trial name
- PIPPA (NCT07590999)
- Testing
- Multi-strain probiotic
- Where
- United Kingdom
- Volunteers
- 106 people
- Sponsor
- University of Oxford
Occupational Health, Stress
Implementation of the ASCEND Training for Supervisors in Dutch Small and Medium-sized Enterprises (SMEs)
This cluster randomized controlled trial (cRCT) aims to evaluate the effectiveness of the Dutch adaptation of an in-person group intervention for workplace supervisors - Advancing Supervisors' Capacity for Mental Health at Work…
- Conditions
- Occupational Health, Stress, Burnout, Mental Health Conditions
- Trial name
- NCT06989398
- Testing
- Advancing Supervisors' Capacity for Mental Health at Work (ASCEND)
- Where
- Netherlands
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- VU University of Amsterdam
Mental Health Wellness 1, Well-Being, Psychological
Support Groups in the Metaverse for Ukrainian Refugees
The goal of this clinical trial is to test the efficacy of support groups held in the Metaverse, designed to promote mental health and well-being in Ukrainian refugees.
- Trial name
- METASUPUKR (NCT06142032)
- Testing
- Metaverse support group, In-Person support group
- Where
- Romania
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Bucharest
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