Clinical trials: Psychological Disorder
Bipolar Depression
Biosignatures of Latuda for Bipolar Depression
The study proposes to conduct a pilot study of biological predictors of lurasidone response in bipolar depression.
- Trial name
- NCT02239094
- Testing
- Lurasidone (Latuda)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- New York State Psychiatric Institute
Treatment Resistant Depression (TRD)
Maintenance TMS in Treatment Resistant Depression
Electroconvulsive therapy (ECT) is one of the most efficacious treatments available for treatment-resistant depression (TRD). Although a maintenance ECT protocol exists, multiple barriers limit its use for long-term use.
- Trial name
- NCT06682299
- Testing
- Transmagnetic Stimulation, Electroconvulsive Therapy
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Austin Messner
Autism Spectrum Disorder
Fatty Acid Supplementation in Children With ASD (Study 2)
The objective of the protocol is to test the impact of Omega 3-6 on pre-specified biological signatures (IL-1β, IL-2, and IFNγ) and to correlate changes in the biological signatures with changes in ASD symptoms.
- Trial name
- NCT04312932
- Testing
- LCPUFA Oil Supplement
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Sarah Keim
Mild Cognitive Impairment
Enhancing Cognitive Control in Mild Cognitive Impairment Via Non-invasive Brain Stimulation
The overall goal of this project is to improve cognitive control abilities in adults with mild cognitive impairment (MCI) through a form of non-invasive brain stimulation, transcranial alternating current stimulation (tACS).
- Trial name
- NCT04647032
- Testing
- Transcranial alternating current stimulation
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Alzheimer's Disease
Resveratrol for Alzheimer's Disease
Resveratrol is derived from plants and is found in highest levels in red wine and the skin of red grapes. A recent study reported that monthly and weekly consumption of red wine is associated with a lower risk of dementia.
- Trial name
- NCT01504854
- Testing
- Resveratrol
- Where
- 26 sites in United States
- Volunteers
- 119 people
- Sponsor
- Alzheimer's Disease Cooperative Study (ADCS)
Insomnia, Sleep Deprivation
Study of the Effects of HIRREM-SOP for Insomnia
Prior research studies have shown benefit for use of a technique called High-resolution, relational, resonance-based, electroencephalic mirroring (HIRREM®), to reduce symptoms of moderate to severe insomnia.
- Trial name
- NCT03607994
- Testing
- HIRREM-SOP, NCC
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Wake Forest University Health Sciences
Methamphetamine or Cocaine Dependence
Doxazosin for Psychostimulant Dependence
Psychostimulant dependence is a major public health problem and no medications have been shown to be very effective in treating this disorder.
- Trial name
- NCT01371851
- Testing
- Doxazosin extended release
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Arkansas
Depression, Marijuana Abuse
Free Venlafaxine Treatment for Marijuana Addiction and Depression - 1
The purpose of this study is to determine if Venlafaxine Extended Release (Ven-XR) is effective in treating individuals with marijuana addiction and depression.
- Trial name
- VEN (NCT00131456)
- Testing
- Venlafaxine
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- New York State Psychiatric Institute
Alzheimer Disease, Hypercholesterolemia
The Clinical Study of Pitavastatin Treatment for Group of Mild to Moderate Alzheimer's Disease
Some studies suggest that statin medications may be effective against Alzheimer's disease. However, this has not been proven. The purpose of this study is to evaluate the efficacy of pitavastatin in patients with mild to moderate…
- Trial name
- PIT-ROAD (NCT00548145)
- Testing
- Pitavastatin, cholesterol-lowering medicine other than statin(e.g.,Ezetimibe,Colestimide)
- Where
- Japan
- Volunteers
- 38 people
- Sponsor
- Osaka University
Prescription Drug Abuse (Not Dependent)
Mobile Application for Prescription Drug-Abuse Education (MAPDE)
The aims of this pilot study are: (1) to assess the feasibility and acceptability of a mobile application to educate military members about the risks of prescription drug misuse; (2) to determine if there is evidence that the…
- Trial name
- MAPDE (NCT03165175)
- Testing
- prescription drug-abuse education smartphone application
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Naval Health Research Center
Tobacco Dependence
Establishing the Effect of Flavor on the Addictive Potential of Electronic Cigarettes
The current study aims to establish proof-of-concept that neural cue-reactivity can serve as an early, objective marker of electronic cigarette (ECIG) addictive potential.
- Trial name
- NCT03905928
- Testing
- Nicotine Containing ECIG with tobacco flavor, Nicotine Containing ECIG with Strawberry Vanilla Flavor
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Binge-Eating Disorder
Efficacy and Mechanisms of Naltrexone+Bupropion for Binge Eating Disorder
This study will test the efficacy of naltrexone HCI and bupropion HCI (NB) versus placebo in patients with binge-eating disorder (BED), with or without obesity.
- Trial name
- NCT03539900
- Testing
- Bupropion Hydrochloride, Naltrexone Hydrochoride Drug Combination
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Yale University
Alzheimer's Disease
A Study to Evaluate the Safety, Tolerability, and Blood Levels of PF-03654746 in Subjects With Mild to Moderate Alzheimer's Disease
This is a study to evaluate the safety, tolerability and blood levels of PF-03654746 in subjects will mild to moderate Alzheimer's disease.
- Trial name
- NCT01028911
- Testing
- PF-03654746
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- Pfizer
Attention Deficit Hyperactivity Disorder (ADHD)
Dose-Optimization Study Evaluating the Efficacy, Safety and Tolerability of Vyvanse (Lisdexamfetamine Dimesylate) in Children Aged 6-12 Diagnosed With ADHD
Assess the efficacy \& tolerability of Vyvanse when children aged 6-12 years diagnosed with ADHD are dosed to optimal effect.
- Trial name
- NCT00500071
- Testing
- Vyvanse (lisdexamfetamine dimesylate)
- Where
- 46 sites in United States
- Volunteers
- 318 people
- Sponsor
- Shire
Schizophrenia
Effectiveness and Safety of 3 Fixed Doses (25 mg eq., 100 mg eq., and 150 mg eq.) of Paliperidone Palmitate in Patients With Schizophrenia
The primary objectives of this study are to evaluate the efficacy and safety of 3 fixed doses of paliperidone palmitate administered i.m. after an initial loading dose of 150 mg eq.
- Trial name
- NCT00590577
- Testing
- Paliperidone palmitate 25 mg eq., Paliperidone palmitate 150 mg eq., Paliperidone palmitate 100 mg eq.
- Where
- 66 sites in United States, Malaysia and 6 more
- Volunteers
- 652 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Bipolar Disorder
Clinical Trial of a Nutritional Supplement in Adults With Bipolar Disorder
The purpose of the trial was to determine whether a 36-ingredient micronutrient supplement (primarily vitamins and minerals) is beneficial for the treatment of bipolar disorder, when studied under randomized and fully blinded…
- Trial name
- NCT00109577
- Testing
- MCN36 (nutritional supplement)
- Where
- 2 sites in United States, Canada
- Volunteers
- 40 people
- Sponsor
- University of Calgary
Major Depressive Disorder
Brexpiprazole as Adjunctive Treatment in Patients With Major Depressive Disorder With an Inadequate Response to Antidepressant Treatment
To evaluate the long-term efficacy and safety of brexpiprazole as an adjunctive treatment to an antidepressant treatment (ADT) for adult patients with Major Depressive Disorder (MDD).
- Trial name
- NCT01838681
- Testing
- Brexpiprazole, ADT
- Where
- 107 sites in United States, Bulgaria and 14 more
- Volunteers
- 1,986 people
- Sponsor
- H. Lundbeck A/S
Alcohol Use Disorder
Development of Ivermectin for Alcohol Use Disorders
Current pharmacotherapies for alcohol use disorders (AUDs) have limited efficacy. Thus, the development of effective treatments for AUDs represents an important public health objective. Repositioning, i.e.
- Trial name
- NCT02046200
- Testing
- Ivermectin, Alcohol
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of California, Los Angeles
Depressive Disorder, Major
Study of Adjunctive or Monotherapy Rapastinel Treatment in Patients With Major Depressive Disorder (MDD)
Multicenter, open-label, long-term extended access treatment protocol in adult patients with a primary diagnosis of MDD.
- Trial name
- NCT03668600
- Testing
- Rapastinel
- Where
- 74 sites in United States
- Volunteers
- 230 people
- Sponsor
- Naurex, Inc, an affiliate of Allergan plc
Depression, Anxiety
Integrating Mindfulness Into the Patient-Centered Medical Home (Phase 2)
Among primary care patients, compare the effectiveness of an 8-week mindfulness-based intervention (Mindfulness Training for Primary Care[MTPC]) vs.
- Conditions
- Depression, Anxiety, Stress Related Disorder, Adjustment Disorders
- Trial name
- MINDFUL-PC-2 (NCT03265600)
- Testing
- Mindfulness Training for Primary Care, 60-minute Introduction to Mindfulness
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Cambridge Health Alliance
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