Clinical trials: Psychological Disorders
Asthenia, COVID-19
Efficacy of the Therapy With BRAINMAX® Using fMRI for the Treatment of Patients With Asthenia After COVID-19
to assess executive network using resting-state fMRI and patterns of brain activation using task fMRI with a cognitive paradigm, against the background of taking the drug in comparison with placebo in patients with post-COVID…
- Conditions
- Asthenia, COVID-19, Functional MRI, Cognitive Impairment
- Trial name
- NCT05939622
- Testing
- Structural and functional MRI, Ethyl methyl hydroxypyridine succinate + Meldonium
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- Promomed, LLC
Alzheimer Disease, Cognition Disorder
Study to Evaluate the Effects of Single Ascending Oral Doses of ACD856 on Safety, Tolerability and Pharmacokinetics
The SAD design of the study is based on the aim to study safety, tolerability and PK of selected doses of ACD856 in a limited number of healthy volunteers. ACD856 will be administered orally.
- Trial name
- NCT05077631
- Testing
- ACD856, ACD856 (fed cohort)
- Where
- Sweden
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- AlzeCure Pharma
Bipolar Disorder, Mania
Safety and Efficacy Study of Lithium in Bipolar Disorder
The purpose of this study is to determine whether Lithium is safe and effective in the treatment of Bipolar I Disorder subjects with symptoms of acute mania.
- Trial name
- NCT00422331
- Testing
- Lithium Carbonate Capsule
- Where
- United States
- Volunteers
- 206 people
- Sponsor
- JDS Pharmaceuticals
Autism Spectrum Disorder, Childhood
Preliminary Exploration of the Usability of a Structured Plate to Improve Eating Behaviors in Children With Autism Spectrum Disorder and Its Impact on the Family: A Pilot Study
This completed single-arm pilot study examined the usability of a structured plate during routine classroom mid-morning snacks in children with autism spectrum disorder and feeding difficulties.
- Conditions
- Autism Spectrum Disorder, Childhood, Feeding Difficulties
- Trial name
- PlaTEA (NCT07516431)
- Testing
- Structured Plate
- Where
- Spain
- Volunteers
- 6 people
- Sponsor
- Universidad de Zaragoza
Depression, Anxiety
Treating Depression and Anxiety in the Cardiac Rehabilitation Pathway
Cardiac rehabilitation (CR) services aim to improve heart disease patients' health and quality of life, and reduce the risk of further cardiac events.
- Conditions
- Depression, Anxiety, Cardiac Rehabilitation
- Trial name
- PATHWAY (NCT02420431)
- Testing
- Metacognitive Therapy, Cardiac Rehabilitation (treatment as usual)
- Where
- 5 sites in United Kingdom
- Volunteers
- 332 people
- Sponsor
- University of Manchester
Polypharmacy, Insomnia
MIDAS Cluster Randomized Controlled Trial of Implementation Strategies to Optimize Use of Medications in VA Clinical Settings
Scientific advances are constantly leading to better treatments. However, it is quite challenging for healthcare systems, including VA, to ask very busy providers to change the way they practice.
- Conditions
- Polypharmacy, Insomnia, Anticoagulants
- Trial name
- MIDAS cRCT (NCT05065502)
- Testing
- Academic Detailing (AD), LEAP
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- VA Office of Research and Development
Dementia Alzheimers
Surface EMG to Measure Paratonia in Dementia
Rationale: A prominent and degenerative motor symptom of dementia is paratonia that heavily affects quality of life. However, paratonia is poorly recognized and the diagnosis yet relies on subjective evaluation by caregivers.
- Trial name
- NCT05606445
- Testing
- Elbow movement
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Substance Use, Conduct Disorder
Early Family-Centered Prevention of Drug Use Risk (Aka Early Steps)
The investigators are testing the efficacy of a family-based preventive intervention, which began when the children were age 2, with children at risk for developing significant conduct problems.
- Conditions
- Substance Use, Conduct Disorder, Depression, Anxiety
- Trial name
- Early Steps (NCT01098695)
- Testing
- Ecological Family Intervention and Treatment (EcoFIT)
- Where
- 3 sites in United States
- Volunteers
- 731 people
- Sponsor
- University of Oregon
Opioid Use
FOREward Together: Training Peer Recovery Coaches to Promote Retention and Adherence to MOUD
This project aims to implement a peer-led intervention to support retention and adherence to medications for opioid use disorder among low-income adults in Detroit, as well as a training manual for peer recovery coaches serving…
- Trial name
- NCT05098795
- Testing
- Behavioral Activation (BA)
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Henry Ford Health System
Ultra High Risk for Psychosis
Placebo-controlled Trial in Subjects at Ultra-high Risk for Psychosis With Omega-3 Fatty Acids in Europe
The purpose of this study is to determine whether omega-3 fatty acids are effective in the prevention of psychosis in individuals at ultra-high risk for psychosis.
- Trial name
- PURPOSE (NCT02597439)
- Testing
- Omega-3 fatty acids
- Where
- 14 sites in Austria, Germany and 7 more
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Rene Kahn
Major Depressive Disorder, Depression in Adolescence
Accelerated Intermittent Theta Burst in Treatment-Naive Adolescents
This is a single-site open-label clinical trial of fMRI-guided accelerated intermittent theta burst stimulation. The goal of this clinical trial is to learn if a new form of transcranial magnetic stimulation (TMS)-known generally…
- Conditions
- Major Depressive Disorder, Depression in Adolescence, Depression, Major Depressive Episode
- Trial name
- paiTBS-KID (NCT06523439)
- Testing
- MagPro X100 edition (MagVenture, Skovlunde, Denmark)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Texas at Austin
Mild Cognitive Impairment
Memory Training and Neural Plasticity
This study will evaluate the efficacy of working memory training in older adults with amnestic mild cognitive impairment (MCI).
- Trial name
- WMTrain (NCT05380739)
- Testing
- Working Memory Training
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Michigan
Tinnitus
FR-taVNS Tinnitus Tria
Tinnitus is a common neurosensory symptom affecting 12-30% of adults and is closely associated with anxiety, sleep disturbance, and autonomic dysregulation.
- Trial name
- NCT07711639
- Testing
- True Foot Reflexology, True ta-VNS, True Auricular Acupressure
- Where
- Taiwan
- Volunteers
- 180 people
- Sponsor
- Tzu Chi University
Social Anxiety
Treating Negative Mental Images and Memories in Social Anxiety
The proposed research will study the effects of Imaginal Rescripting (IR) for social anxiety disorder (SAD). IR guides patients to change their memories of past socially painful events.
- Trial name
- NCT03140839
- Testing
- Imaginal Rescripting, Imaginal Exposure, Supportive Counselling
- Where
- Canada
- Volunteers
- 33 people
- Sponsor
- University of Waterloo
Emotional Disorder, Anxiety Disorders
The Unified Protocol for the Treatment of Emotional Disorders in Spanish Public Mental Health System
The present randomized, controlled trial will compare the cost-efficacy and acceptability of the Unified Protocol in group format against traditional individual Cognitive Behavioral Treatment in a sample of patients with…
- Conditions
- Emotional Disorder, Anxiety Disorders, Depressive Disorder
- Trial name
- NCT03064477
- Testing
- Unified Protocol, Cognitive Behavioral Therapy (TAU)
- Where
- 3 sites in Spain
- Volunteers
- 200 people
- Sponsor
- Universitat Jaume I
Postintensive Care Syndrome, Anxiety Disorder
Is Invasive ICU-treatment Associated With Mental Illness?
Understanding long-term complications after intensive care is important to be able to offer prophylactic and therapeutic measures to post-intensive care unit (ICU) patients.
- Conditions
- Postintensive Care Syndrome, Anxiety Disorder, Depression, PTSD
- Trial name
- NCT05137977
- Testing
- Intensive Care
- Volunteers
- 1,048,576 people
- Sponsor
- Uppsala University
Alcohol Use Disorder
Clinical and Mechanistic Effects of Psilocybin in Alcohol Addicted Patients
Effects of serotonin 2A/1A receptor stimulation by psilocybin on alcohol addicted patients: a randomized double-blind placebo-controlled study
- Trial name
- NCT04141501
- Testing
- Psilocybin
- Where
- Switzerland
- Volunteers
- 37 people
- Sponsor
- University of Zurich
Aortic Stenosis, Amyloid
Atrial Amyloid May Influence Outcomes in Patients Undergoing Surgical Aortic Valve Replacement
Background (Context): Some older adults who undergo surgery to replace a narrowed heart valve (called aortic stenosis) may also have small protein deposits in their heart.
- Trial name
- AORTICMARKER (NCT07105501)
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- Germans Trias i Pujol Hospital
Labor Pain, Yoga
Nada Yoga Music Therapy for Pain and Anxiety in Labor
This study was designed as a randomized controlled trial. Based on the power analysis (Cohen's d = 0.80, α = 0.05, power = 80%), a total of 52 pregnant women were included, with 26 participants in the intervention group and 26 in…
- Conditions
- Labor Pain, Yoga, Music Therapy
- Trial name
- NCT07392112
- Testing
- Nada Yoga music therapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Sinop University
Alzheimer Disease
Effect of Probiotics in Alzheimer's Disease
In this clinical trial, five strains of probiotics (Bifidobacterium breve Bv-889, B. longum subspecies infantis BLI-02, B. bifidum VDD088, B. animalis subsp.
- Trial name
- NCT05145881
- Testing
- Low dose probiotics, Normal dose probiotics
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Hsieh-Hsun Ho
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.