Clinical trials: Psychological Disorders
Sleep, Alzheimer Disease
Sleep Trial to Prevent Alzheimer's Disease
The purpose of this study is to determine if treatment with the sleep aid suvorexant can decrease the rate of amyloid-β (Aβ) accumulation in the brain.
- Trial name
- SToP-AD (NCT04629547)
- Testing
- Suvorexant 20 mg
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Emergence Delirium, Anesthesia
Turkish Version of The Pediatric Anesthesia Emergency Delirium
Emergence delirium (ED) is a mental disorder seen in children during recovery from general anesthesia. The Pediatric Anesthesia Emergence Delirium (PAED) scale is the only valid scale to assess ED in pediatric patients undergoing…
- Trial name
- PAED (NCT06931249)
- Testing
- The observational study
- Where
- Turkey (Türkiye)
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Cerebral Small Vessel Diseases
Clinical Observation for the Therapeutic Effect of mNGF on Cognitive Decline in Cerebral Small Vessel Disease
This study was a multicenter, prospective, randomized controlled trial. In this study, 510 patients with cognitive impairment of cerebral small vessel disease who met the inclusion criteria are randomly included in multiple…
- Trial name
- NCT04041349
- Testing
- mouse nerve growth factor
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Zhujiang Hospital
Stress Resilience, Systemic Inflammation
Oral Supplementation With 1 mg of KGA-10 Daily (a Novel Environmentally-derived Mycolicibacterium) for Stress, Sleep, and Inflammation
The goal of this clinical trial is to learn if a novel strain of heat-killed Mycolicibacterium that is being considered by the International Code of Nomenclature of Prokaryotes (ICNP) as candidate species and type strain…
- Conditions
- Stress Resilience, Systemic Inflammation, General Wellbeing, Sleep Quality
- Trial name
- NCT07604038
- Testing
- Mycolicibacterium petrae KGA-10 (heat-killed)
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Kioga Inc.
Estazolam-dependent Insomnia
A Randomized Controlled Trial of Auricular Acupressure in Treating Estazolam-dependent Insomnia
Insomnia is a disorder characterized by difficulties in falling asleep, maintaining sleep or waking up too early, and impairment of daytime functioning.
- Trial name
- ESAAEDI (NCT06258226)
- Testing
- Conventional dosage reduction, Auricular acupressure
- Volunteers
- 108 people
- Sponsor
- Wenzhou Central Hospital
Depressive Disorder, Major
Open-Label, Randomized Study Evaluating Treatment With Venlafaxine Extended-Release Plus Dialogues Time to Talk Program
The purpose of this study is to evaluate the effect of the Dialogues Time to Talk program in subjects treated with Venlafaxine Extended Release (ER).
- Trial name
- NCT00401726
- Testing
- Venlafaxine ER, Dialogues Time to Talk Program
- Where
- 44 sites in United States
- Volunteers
- 537 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Obsessive-Compulsive Disorder and Symptoms
Brief Anxiety Sensitivity Treatment for Obsessive Compulsive Symptoms
Obsessive-compulsive disorder (OCD), characterized by recurrent obsessions and/or compulsions, is a disabling psychiatric condition affecting approximately 2-3% of the population.
- Trial name
- COAST (NCT02635178)
- Testing
- Cognitive Anxiety Sensitivity Treatment, Physical Health Education Training
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Florida State University
PARKINSON DISEASE (Disorder), Parkinson Disease (PD)
Cognitive-Based Balance Rehabilitation in Parkinson's Disease: Virtual Reality vs. Dual Task
This prospective, randomized, single-blind, controlled clinical trial aims to evaluate and compare the efficacy of cognitive-based balance rehabilitation delivered via immersive Virtual Reality (VR) versus traditional Dual-Task…
- Conditions
- PARKINSON DISEASE (Disorder), Parkinson Disease (PD), Parkinson s Disease, Postural Instability
- Trial name
- NCT07660978
- Testing
- Dual Task Training (DTT), Virtual Reality Training (VRT)
- Volunteers
- 34 people
- Sponsor
- Bezmialem Vakif University
Anxiety, Pain
Effect of the 4-7-8 Breathing Technique Before Central Venous Catheter Insertion
Purpose: This study aims to evaluate the effect of the 4-7-8 breathing technique applied before central venous catheter (CVC) insertion on patients' anxiety, pain, and vital signs.
- Conditions
- Anxiety, Pain, Vital Sign Evaluation, 4-7-8 Breathing Technique
- Trial name
- NCT07917585
- Testing
- 4-7-8 breathing technique
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mersin University
Schizophrenia, Schizoaffective Disorder
Clozapine-Augmentation With Ziprasidone or Risperidone, a Randomized, Prospective Trial
We aim to compare the augmentation of clozapine with ziprasidone or risperidone in a randomized, prospective manner.
- Trial name
- NCT00224315
- Testing
- ziprasidone, risperidone
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Anxiety, Insomnia
Augmenting Benzodiazepine Receptor Agonist Deprescribing With Acupuncture and Yoga Among Older Adults
The main purpose of this 12-week study is to see if a new combination of treatments can help older adults reduce benzodiazepine or related medication use.
- Conditions
- Anxiety, Insomnia, Benzodiazepine, Deprescription
- Trial name
- NCT06197243
- Testing
- Acupuncture, Yoga, Deprescribing
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Anterior Ischemic Optic Neuropathy
PDE5 Inhibitor Use and Non-arteritic Anterior Ischemic Optic Neuropathy (NAION)
The primary objective of this study is to determine whether the use of PDE5 inhibitors (vardenafil, sildenafil, or tadalafil) increases the risk for the development of NAION.
- Trial name
- NCT00867815
- Testing
- Diagnostic procedures
- Where
- 13 sites in United States, Australia and 1 more
- Volunteers
- 10 people
- Sponsor
- Bayer
Smoking Cessation, Smoking Behaviors
Clinical Learning Study for a Mobile Smoking Cessation Program
The purpose of this study are to obtain learnings regarding the Digital Therapeutic (DTx) experience of Clickotine, including acceptability and preference of the overall program and specific DTx components, as well as to obtain…
- Conditions
- Smoking Cessation, Smoking Behaviors, Smoking Reduction, Smoking, Cigarette
- Trial name
- NCT04857515
- Testing
- Clickotine®
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Click Therapeutics, Inc.
Schizophrenia, Schizoaffective Disorder
Effectiveness and Mechanisms of Recovery Oriented Cognitive Therapy
This study is evaluating the effectiveness of recovery oriented cognitive therapy (CT-R) for patients with schizophrenia/schizoaffective disorder.
- Trial name
- NCT05140135
- Testing
- Recovery Oriented Cognitive Therapy (CT-R), Treatment as Usual
- Where
- United States
- Sponsor
- University of Pennsylvania
Breast Cancer
Evaluation of Group CBT Programme With Breast Cancer Patients
The purpose of this study is to examine whether a group CBT intervention is effective in reducing psychological distress in women with primary breast cancer.
- Trial name
- NCT00426335
- Where
- United Kingdom
- Volunteers
- 78 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Neurodegenerative Diseases, Parkinson Disease
Saliva and Extracellular Vesicles for Neurodegenerative Diseases
Early diagnosis of Neurodegenerative diseases (NDDs) and accurate patient profiling are key goals needed to tailor prompt personalized therapeutic strategies that can significantly impact disease progression and patients' quality…
- Conditions
- Neurodegenerative Diseases, Parkinson Disease, Alzheimer Disease, Parkinsonism
- Trial name
- MINERVA (NCT06869135)
- Testing
- Saliva collection, longitudinal
- Where
- 5 sites in Italy
- Volunteers
- 242 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Perfectionism, Shame
Can a Self-guided Mobile Phone Application Program Improve Wellbeing in University Students
This study seeks to evaluate and compare the effectiveness of a mobile phone application-based intervention in improving wellbeing in young adults. 400 University students are randomized into 1 of 4 intervention types.
- Conditions
- Perfectionism, Shame, Depression, Anxiety, Stress
- Trial name
- NCT05475535
- Testing
- Cognitive Behavioural Therapy, Self-Compassion, Active Control
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Bipolar Disorder
Pediatric Bipolar Disorder Study at UCLA
The UCLA Semel Institute for Neuroscience in Los Angeles, CA, is conducting a study looking at similarities and differences in how the brain works between bipolar disorder and attention deficit hyperactivity disorder (ADHD).
- Trial name
- NCT00961935
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Los Angeles
Cognitive Dysfunction
Brain-Induced Neurotrophic Factor Levels in Patients Undergoing Coronary Artery Bypass Surgery
In patients undergoing coronary artery bypass surgery, the relationship between neurocognitive changes seen in the early period and brain-induced neurotrophic factor serum levels will be investigated.
- Trial name
- NCT04250935
- Testing
- Patients with cognitive dysfunction
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Bozok University
Attention Deficit Hyperactivity Disorder
Evaluation of the Effect of rTMS on Attention in Adults Diagnosed With Attention-Deficit Hyperactivity Disorder (ADHD)
The aim of the study is to evaluate the immediate effect of rTMS on attention in adults diagnosed with ADHD. the design is a double blind sham controlled crossover study.
- Trial name
- NCT00825708
- Testing
- rTMS
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Shalvata Mental Health Center
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.