Clinical trials: Psychological Disorders
Memory Disorders, Dementia
Maximizing Independence at Home (MIND at Home)
Funded by a unique private philanthropy and public coalition through THE ASSOCIATED: Jewish Community Federation of Baltimore, this project seeks to develop effective ways to deliver dementia care to older adults with memory…
- Trial name
- NCT01283750
- Testing
- care coordination
- Where
- United States
- Volunteers
- 303 people
- Sponsor
- Johns Hopkins University
Postpartum Complication, Posttraumatic Stress Symptoms
Labor Education to Reduce Postpartum Traumatic Stress
The goal of this randomized controlled trial is determine if education on common events in labor in nulliparous women can reduce the postpartum traumatic symptoms.
- Trial name
- LEPT (NCT06992791)
- Testing
- Prenatal Education on Childbirth
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Alcohol Use Disorder, Ketosis
Effects of Ketones on Brain Energetics and Alcohol Consumption in Alcohol Use Disorder
This is a randomized, double-blind, crossover trial to evaluate the immediate effects of a nutritional ketone supplement, Kenotic compared to placebo on brain function and alcohol consumption in individuals with alcohol use…
- Trial name
- KABA (NCT06807918)
- Testing
- Kenetik, magnetic resonance imaging scan, Alcohol bar lab
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Pennsylvania
Peritoneal Dialysis, Cardiovascular Diseases
The Effect of Physical Activity Level Evaluated by Wrist-wearable Devices on Cardiovascular Disease Risk and Other Outcomes in Peritoneal Dialysis Patients
This study aims to explore how daily physical activity (PA) levels affect the heart health and cognitive function of patients on peritoneal dialysis (PD).
- Conditions
- Peritoneal Dialysis, Cardiovascular Diseases, Myocardial Infarct, Heart Failure
- Trial name
- NCT06697418
- Where
- China
- Volunteers
- 266 people
- Sponsor
- Ruijin Hospital
Peri-menopausal Women, Sleep Disturbances
Study of Effects of Dao-In Exercise on the Perimenopausal Women With Sleep Disturbance
Among health problems of peri-menopausal women, sleep disturbances is very common complaint. The aim of this study is to realize the body constitution of the peri-menopausal women with sleep disturbance; and to evaluate the…
- Conditions
- Peri-menopausal Women, Sleep Disturbances, Dao-in Exercise, Body Constitution
- Trial name
- NCT02541318
- Testing
- Duo-in exercise
- Where
- 4 sites in Taiwan
- Volunteers
- 100 people
- Sponsor
- China Medical University Hospital
Alzheimer Disease, Dementia
Shanghai At Risk for Alzheimer's Disease: a Cohort Study
The goal of this cohort study is to estimate the incidence of AD in the first-degree relatives of patients with AD. The main questions it aims to answer are: cognitive changes of subjects at high risk of AD as ageing…
- Conditions
- Alzheimer Disease, Dementia, Neurodegenerative Diseases, Cognitive Impairment
- Trial name
- SHARAD (NCT05597410)
- Where
- China
- Volunteers
- 3,418 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
Autism Spectrum Disorders
Intranasal Oxytocin and Learning in Autism
The main objective of this study is to determine the safety and therapeutic potential of intranasal oxytocin in children and adolescents with autism spectrum disorder (ASD) when paired with a computer game intervention that is…
- Trial name
- NCT01417026
- Testing
- Intranasal Oxytocin (Trade name: Syntocinon)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Robert Schultz
Autism Spectrum Disorder, Implementation Science
Refining and Implementing Technology-Enhanced Family Navigation to Promote Early Access and Engagement With Mental Health Services for Youth With Autism
This project, Refining and Implementing Technology-Enhanced Family Navigation to Promote Early Access and Engagement with Mental Health Services for Youth with Autism (ATTAIN NAV) is focused on adapting and implementing family…
- Conditions
- Autism Spectrum Disorder, Implementation Science, Mental Health, Behavioral Health
- Trial name
- ATTAIN NAV (NCT05344378)
- Testing
- ATTAIN NAV Technology-Enhanced Family Navigation Model
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Premature Birth, Obstetric Labor, Premature
Family Nurture Intervention in the NICU at The Valley Hospital
The purpose of this study is to compare neurodevelopment and activity in infants born preterm (25 to 34 1/7 weeks gestational age (GA)) receiving Standard Care (SC) or Family Nurture Intervention (FNI) in the neonatal intensive…
- Trial name
- NCT03267043
- Testing
- Family Nurture Intervention (FNI), Standard Care
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Columbia University
Schizophrenia, Schizoaffective Disorder
Selective Estrogen Receptor Modulators - A Potential Treatment for Psychotic Symptoms of Schizophrenia
The aim of the project is to investigate the use of Raloxifene (a new form of estrogen) in the treatment of women with schizophrenia and schizoaffective disorder.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder
- Trial name
- SERM (NCT00361543)
- Testing
- Raloxifene hydrochloride, Lactose Capsules
- Where
- Australia
- Volunteers
- 54 people
- Sponsor
- The Alfred
Caries Active
Anxiety During Caries Removal Using Chemo-mechanical Versus Conventional Methods
This study aims to clinically assess this newly introduced Egyptian chemo-mechanical caries removal gel versus conventional drilling method .
- Trial name
- NCT07344415
- Testing
- Cariemove, Drilling using bur
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Overweight and Obesity, Time Restricted Feeding
Fasting ENHANCE Pilot Study
Grounded in the principles of geroscience, the proposed Fasting ENHANCE study will test whether a time restricted eating (TRE) regimen can improve cognitive function and other aspects of successful aging in a safe and sustainable…
- Conditions
- Overweight and Obesity, Time Restricted Feeding, Alzheimer Disease
- Trial name
- NCT05732935
- Testing
- Time Restricted Eating intervention, Successful Aging Comparison Group (LEARN)
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Florida
Alcoholic Liver Disease, Alcoholic Fibrosis of Liver
Early Detection of Alcoholic Liver Disease
This is an observational study to identify the prevalence of advanced liver fibrosis among patients with excessive alcohol intake using a non-invasive method (FibroScan®) and to characterize the main environmental, genetic and…
- Conditions
- Alcoholic Liver Disease, Alcoholic Fibrosis of Liver, Alcoholic Cirrhosis, Excessive Drinking
- Trial name
- NCT04070508
- Sponsor
- University of Pittsburgh
Post Traumatic Stress Disorder
The Effect of Intranasal Oxytocin on Emphatic Abilities in Patients With Post Traumatic Stress Disorder (PTSD)
Oxytocin (OT) - a neurohormone and neuromodulator which is mainly synthesized in the hypothalamus - is a key mediator of complex social and affective behaviors, including emotional empathy.
- Trial name
- NCT01325168
- Testing
- syntocinon nasal spray
- Where
- 2 sites in Israel
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Bipolar Disorder, Psychiatric Morbidity
Bipolar Disorder in Pregnancy and the Postpartum Period: Predictors of Morbidity
The purpose of this study is to examine risk factors for relapse of bipolar disorder during pregnancy and the postpartum period.
- Conditions
- Bipolar Disorder, Psychiatric Morbidity, Neonatal Outcome
- Trial name
- NCT00580268
- Where
- 2 sites in United States
- Volunteers
- 118 people
- Sponsor
- Massachusetts General Hospital
Depression
p11 Protein Levels in Patients With Major Depressive Disorder Treated With Citalopram
This study will compare levels of p11 protein in people with and without major depressive disorder (MDD) and examine if p11 levels in patients are affected by treatment with citalopram (Celexa).
- Trial name
- NCT00697268
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Equine-assisted Therapy, Children
Impact of Equine-Assisted Therapy on the Quality of Life of Children With Autism Spectrum Disorders (ASD)
The main objective of this research is to measure the influence of equine-assisted therapy sessions on the quality of life of children with ASD, using the PedsQL™ 4.0 questionnaire as an evaluation tool.
- Conditions
- Equine-assisted Therapy, Children, Autism Spectrum Disorder, Quality of Lifte
- Trial name
- EQUI-TSA (NCT06698068)
- Testing
- Equine-assisted therapy
- Where
- France
- Volunteers
- 11 people
- Sponsor
- Hopital La Musse
Autism Spectrum Disorder
Integrating the ESDM in ASD Preschools in Israel
The current study evaluates the effectiveness of the Early Start Denver Model (ESDM) when integrated in existing community preschools for children with ASD.
- Trial name
- ESDM-ISR (NCT03362840)
- Testing
- Early Start Denver Model, Eclectic preschool intervention
- Where
- Israel
- Volunteers
- 59 people
- Sponsor
- Bar-Ilan University, Israel
Neck Pain, Patient Education
Effects of Education and Exercise on Pain, Psychosocial Factors, and Upper Limb Function in Non-specific Neck Pain.
Pain neuroscience education is currently one of the techniques being explored in physiotherapy for pain management. The benefits of this technique are gradually becoming evident in various published studies.
- Conditions
- Neck Pain, Patient Education, Exercise Therapy, Fear
- Trial name
- PNE-EXNP (NCT06889389)
- Testing
- Education, Excercise
- Where
- Spain
- Volunteers
- 81 people
- Sponsor
- Universidad Miguel Hernandez de Elche
Autism Spectrum Disorder, Fragile X Syndrome
Speech-in-noise Perception in Autism and Fragile X
The goal of this study is to identify which brain regions are active during speech-in-noise perception, as well as how those regions interact.
- Trial name
- NCT06088589
- Testing
- Mismatch negativity
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
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