Clinical trials: Psychological Disorders
Obsessive Compulsive Disorder, Healthy
Cortical Excitability in Obsessive-Compulsive and Related Disorders
This study will use transcranial magnetic stimulation (TMS) to study the function of the cerebral cortex (outer layer of the brain) in people with obsessive compulsive disorder (OCD) and related disorders.
- Trial name
- NCT00029068
- Where
- United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Subclinical Hypothyroidism
Subclinical Hypothyroidism and Mind in the Elderly
Some recommendations of expert consensus on subclinical hypothyroidism (SH) are controversial in those areas with not enough information to reach a conclusion, such as not recommending treatment with thyrotrophic hormone of 4-10…
- Trial name
- NCT00921050
- Testing
- levothyroxine sodium
- Where
- 2 sites in Mexico
- Volunteers
- 70 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Dementia
Going Down Memory Lane: A Technological Intervention
Over 90% of people living with dementia (PLWD) experience behavioural and psychological symptoms of dementia, including apathy, depression, sleep disruptions, wandering, repetitive behaviours and anxiety.
- Trial name
- NCT04131374
- Testing
- Reminiscence Therapy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Depressive Disorder, Treatment-Resistant
Psilocybin-assisted Interpersonal Therapy for Depression
This is a single-arm, open-label interventional study of psilocybin-assisted interpersonal therapy for treatment resistant depression.
- Trial name
- NCT05581797
- Testing
- Psilocybin-assisted psychotherapy
- Where
- New Zealand
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Otago
Anxiety
Impact of a Child-Parent Preoperative Accompanying Procedure on the Anxiety of Children Aged 5 to 12 With Scheduled Surgery
In France, during surgery, only 4% of parents are present at induction, most often for children with disabilities with iterative interventions.
- Trial name
- I-PPOP (NCT03205397)
- Testing
- Experimental Group, usual care
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Limoges
Sleep Disturbance, Persian Gulf War Syndrome in Veteran
Clinical Benefits of a Novel Sleep-focused Mind-body Program on Gulf War Illness (GWI) Symptoms
The purpose of this study is to investigate clinical benefits of a novel sleep-focused mind-body program on Gulf War Illness (GWI) symptoms.
- Trial name
- NCT01543997
- Testing
- Mind-Body Bridging Program, Supportive Education
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- University of Utah
Autism Spectrum Disorder
Combination of Predictive Biomarkers to Increase Diagnostics Efficiency of Autism Spectrum Disorder
Early identification and diagnosis of autism spectrum disorder (ASD) is necessary to promote access to early treatment. Despite the high incidence, in Italy it is estimated that 1 in 77 children (age 7-9 years) (Narzisi et al.…
- Trial name
- NCT05796310
- Testing
- Salivary collection, eye-tracking recorder, neuropsychological assessment
- Where
- Italy
- Volunteers
- 28 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Posttraumatic Stress Disorder
Dose-Response Study of MDMA-assisted Psychotherapy in People With PTSD
The goal of this clinical trial is to learn if MDMA in combination with therapy is safe and effective in people with chronic, treatment-resistant PTSD.
- Trial name
- NCT01793610
- Testing
- Comparator Dose (40mg) MDMA HCl, Active Dose 2 (100 mg) MDMA HCl, Active Dose 1 (125 mg) MDMA HCl
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Resilient Pharmaceuticals
Daytime Wetting, Enuresis
Voiding School as a Treatment of Children's Day-time Incontinence or Enuresis
The Voiding School is a simple educational intervention to treat children with daytime incontinence or enuresis.The purpose of this study is to implement the intervention in primary care, child welfare clinics.
- Conditions
- Daytime Wetting, Enuresis, Functional Incontinence
- Trial name
- NCT03478813
- Testing
- Voiding school
- Where
- Finland
- Sponsor
- Helsinki University Central Hospital
Cognitive Impairment
Development and Application of Portable Multisensory Stimulation Device
This is a study to develop the vibroacustic devices, and to compare the effects between vibroacustic device therapy and music therapy in adults with dementia or with neck pain.
- Trial name
- NCT04005313
- Testing
- vibroacoustic device
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Buddhist Tzu Chi General Hospital
Autism Spectrum Disorder, Behavior Problem
The Family Check-Up in Autism Services
Many children and youth with autism spectrum disorder have high levels of emotional and behavioural problems. Parents play a powerful role in supporting their children's well-being.
- Conditions
- Autism Spectrum Disorder, Behavior Problem, Emotional Problem
- Trial name
- NCT05280613
- Testing
- Family Check-Up, Treatment as Usual
- Where
- Canada
- Volunteers
- 82 people
- Sponsor
- McMaster University
Psychotic Disorders
Fast Titration Of Quetiapine Versus Currently Approved Titration
The purpose of this study is to evaluate the safety and tolerability of a more rapid dose titration in acute schizophrenic patients compared to the conventional titration.
- Trial name
- NCT00254813
- Testing
- Quetiapine
- Where
- 7 sites in Norway
- Volunteers
- 150 people
- Sponsor
- AstraZeneca
BIPOLAR DISORDER
Involvement of the Sodium Pump and Endogenous Digitalis-like Compounds in Bipolar Disorder
This study deals with the possible molecular mechanisms that underlie the etiology of bipolar disorders (BD). Previous studies have implicated Na+, K+-ATPase and endogenous digitalis-like compounds (DLC) in the depressive state…
- Trial name
- NA\K-MANIA (NCT01322113)
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Hadassah Medical Organization
Major Depression
Depression: The Search for Treatment-Relevant Phenotypes-Pilot Study
We are doing this pilot study to learn more about four aspects of treating depression: 1. The features of a depressed person's mood and anxiety and how these features affect a person's capacity to get better and stay better. 2.
- Trial name
- NCT00222820
- Testing
- escitalopram, Interpersonal Psychotherapy
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Pittsburgh
Cognitive Dysfunction
Cognitive Dysfunction in Patients With Cancer Pain
To investigate the occurrence of cognitive dysfunction in cancer patients with pain in China.Analysis of patients with different cancer pain, different analgesic drugs and different treatments are associated with the severity of…
- Trial name
- NCT03641820
- Where
- China
- Volunteers
- 928 people
- Sponsor
- Fujian Cancer Hospital
Sedation, Tolerance
Randomized Study With Midazolam for Sedation in Flexible Bronchoscopy
The Flexible Bronchoscopy (FB) is a diagnostic and therapeutic procedure which is not usually tolerated by the patient. This makes the examination more difficult and a repetition of the examination, if necessary, resulting in a…
- Conditions
- Sedation, Tolerance, Anxiety, Satisfaction
- Trial name
- NCT01038882
- Testing
- Midazolam, Physiological serum
- Where
- Spain
- Volunteers
- 238 people
- Sponsor
- Hospital Universitario La Fe
Dementia, Alzheimer Disease
Translating a Dementia Caregiver Intervention Into a Mobile Application
The overall goal of this development project is to combine elements of two efficacious interventions into a mobile health (mHealth) App for informal dementia caregivers.
- Conditions
- Dementia, Alzheimer Disease, Caregiver Burnout
- Trial name
- NCT04330482
- Testing
- CARE-Well App, Internet Links
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Healthy
Lavender Essential Oil-based Product System for Sleep
The goal of this clinical trial is to learn whether lavender essential oil-based product system can affect gene expression, serum protein markers, and sleep quality in healthy volunteers.
- Trial name
- NCT06510335
- Testing
- Lavender essential oil-based product system
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- dōTERRA International
Nicotine Addiction, Smoking Cessation
Computer-Facilitated 5A's for Smoking Cessation in Primary Care
This study tests the use of handheld computer tablets to promote the integration of 5A's (Ask, Advise, Assess, Assist, Arrange) for smoking cessation in academic and community primary care clinics.
- Trial name
- NCT02046408
- Testing
- Computer Tablet
- Where
- 2 sites in United States
- Volunteers
- 961 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Health, Subjective, Work Related Stress
Evaluation of the CHIME Intervention for Improving Early Head Start/Head Start Educator Well-being
This study will test how well a mindfulness-based intervention called CHIME improves the emotional well-being of educators in Early Head Start and Head Start (EHS/HS) settings.
- Conditions
- Health, Subjective, Work Related Stress, Compassion, Social Skills
- Trial name
- CHIME (NCT05791825)
- Testing
- Cultivating Healthy Intentional Mindful Educators
- Where
- United States
- Volunteers
- 571 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
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