Clinical trials: Psychological Disorders
Bipolar Disorder
Effectiveness RCT of Customized Adherence Enhancement
Approximately one in two individuals with bipolar disorder (BD) are non-adherent with medication, often leading to severe and negative consequences.
- Trial name
- CAE-E (NCT04622150)
- Testing
- Customized Adherence Enhancement (CAE), Enhanced Treatment as Usual (eTAU)
- Where
- 3 sites in United States
- Volunteers
- 190 people
- Sponsor
- Case Western Reserve University
Oncologic Diseases
Financial Toxicity (FT) for Radiotherapy (RT) Patients in Italy: a yAIRO (Associazione Italiana Radioterapia e Ocologia Clinica) Multicenter Study
Non- profit, multicenter, prospective, observational study. The study aims to assess financial toxicity (FT) in patients undergoing radiotherapy for oncological diseases, assessed with a validated questionnaire (Patient Reported…
- Trial name
- FIT-RT (NCT07175350)
- Testing
- PROFFIT
- Where
- 7 sites in Italy
- Volunteers
- 1,000 people
- Sponsor
- Valerio Nardone
Parents
New Programme for Antenatal Preparation for Early Parenthood
Becoming a parent is a challenging stage in life, which provokes feelings of both excitement and insecurity; parents strive to develop confidence in their parenting role.
- Trial name
- NCT03679520
- Testing
- New programme, Regular programme
- Where
- 7 sites in Sweden
- Volunteers
- 71 people
- Sponsor
- Region Skane
Cognitive Dysfunction, Acquired Brain Injury
Fareon Open Label Device Clinical Trial
The purpose of this study is to assess the safety and feasibility of an at-home MMT treatment in patients with cognitive dysfunction related to acquired brain injury, Long COVID, traumatic brain injury, myalgic encephalomyelitis…
- Conditions
- Cognitive Dysfunction, Acquired Brain Injury, Traumatic Brain Injury
- Trial name
- NCT07600320
- Testing
- Fareon device
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Pregnancy, Pain
The Effect of Affirmation During Non-Stress Test on Pain, Anxiety, Fear, and Stress
This study will examine whether positive affirmations used during the Non-Stress Test (NST) can help reduce pain, anxiety, fear, and stress in pregnant women.
- Conditions
- Pregnancy, Pain, Anxiety, Fear
- Trial name
- NST-AFFIRMATIO (NCT07667920)
- Testing
- Affirmation Practice During Non-Stress Test
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Bipolar Disorder
A Double-Blind Placebo Controlled Trial of Riluzole in Bipolar Depression
The Johns Hopkins Department of Psychiatry is conducting a research study to examine the effectiveness of riluzole in treating the depressed phase of bipolar disorder.
- Trial name
- NCT00376220
- Testing
- Riluzole
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Johns Hopkins University
Mild Cognitive Impairment
Effects of rTMS on the Cognition of Elderly With Mild Memory Complaints
Memory is constituted by a set of mental abilities of information processing that will be available at a later time. Flawless performance depends on several brain systems and other cognitive domains.
- Trial name
- TMSMemOld (NCT01292382)
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- Brazil
- Volunteers
- 34 people
- Sponsor
- University of Sao Paulo General Hospital
Major Depressive Disorder
Treating Major Depressive Disorder With Music and Low-frequency Rhythmic Sensory Stimulation
Major depressive disorder (MDD) is a highly prevalent and disabling disorder associated with persistent low mood, loss of the capacity to experience pleasure (i.e.
- Trial name
- NCT02685982
- Testing
- Rhythmic Sensory Stimulation
- Volunteers
- 20 people
- Sponsor
- University Health Network, Toronto
Neuropsychological Rehabilitation Program (VIRTRAEL/LUCCIDY), Standard Training (TAU)
The Role of Executive Functioning in Complex Post-Traumatic Stress Disorder Among Female Survivors of Intimate Partner Violence
This project aims to investigate neuropsychological alterations in women with PTSD (Post-Traumatic Stress Disorder) and complex PTSD (CPTSD), survivors of intimate partner violence (IPV), and to implement a cognitive stimulation…
- Trial name
- BELIEVE-CPTSD (NCT06706882)
- Testing
- Experimental Training: VIRTRAEL/LUCCIDY, Active Comparator: Standard Training: Reflection Group (TAU) (Andalusian Institute of Women, 2010)
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Restless Legs Syndrome, End Stage Renal Disease
The Effect of Vitamin C and E Therapy on Restless Leg Syndrome in Patients With End Stage Renal Disease on Haemodialysis
This study aims to measure the effectiveness of vitamins C and E on relieving RLS symptoms in end stage renal disease patients on HD
- Trial name
- NCT05350124
- Testing
- Ascorbic acid, Tocopherol
- Volunteers
- 160 people
- Sponsor
- King Abdulaziz University
Tobacco Use Cessation, Post Traumatic Stress Disorders
Tobacco Cessation for Veterans With Post Traumatic Stress Disorder (PTSD)
The goal of this study is to improve the effectiveness of tobacco cessation treatment for veterans with Post Traumatic Stress Disorder (PTSD) through ongoing, integrated care management approach using telehealth and motivational…
- Trial name
- NCT00908882
- Testing
- Motivation Interviewing Counseling
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- US Department of Veterans Affairs
Mental Disorders
Psychosocial Intervention Designed to Familial Reintegration of Homeless With Mental Disorder in Maputo and Matola City
The aim of this project is to describe the mental health status of the homeless people in Maputo and Matola utilising standardised clinical and socio-demographic assessments.
- Trial name
- NCT02936141
- Testing
- Group psychotherapy
- Volunteers
- 71 people
- Sponsor
- Ministry of Health, Mozambique
Schizophrenia and Related Disorders
Tele-group Cognitive Behavioural Family Intervention for Individuals With Schizophrenia and Their Families (Definitive tgCBFI)
This mixed-method study comprises a RCT with a twelve-week post-intervention follow-up and focus group interviews. The RCT study aims to examine the effectiveness of delivering the tgCBFI programme to dyads of people with…
- Trial name
- NCT07121166
- Testing
- tgCBFI programme, Treatment as Usual (TAU)
- Where
- 6 sites in Hong Kong
- Volunteers
- 200 people
- Sponsor
- The Hong Kong Polytechnic University
Dementia, Alzheimer Disease
Care to Plan: a Tailored Resource for Family Members of Persons With Dementia
The present study will refine and conduct a preliminary efficacy evaluation of Care to Plan. Care to Plan is an online care planning tool that provides a succinct and clear overview of various types of dementia caregiver…
- Conditions
- Dementia, Alzheimer Disease, Memory Loss
- Trial name
- NCT03901456
- Testing
- Care to Plan, Usual Care
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Diabetes Mellitus, Diabetes Mellitus, Type 2
Emotional Wellbeing in Diabetes
The investigators want to understand the feasibility and acceptability of implementing COMPASS: Online Cognitive behavioural therapy (CBT) in routine NHS care for individuals with diabetes.
- Conditions
- Diabetes Mellitus, Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1, Diabetes
- Trial name
- NCT05140551
- Testing
- COMPASS: digital CBT
- Where
- 4 sites in United Kingdom
- Volunteers
- 12 people
- Sponsor
- King's College London
Healthy Volunteers
Neurophysiological Correlates of Dissociation Induced by Virtual Reality Hypnosis.
Hypnosis and virtual reality are potential tools in treating acute pain. Nevertheless, the neurophysiological correlates of such tools used together, i.e.
- Trial name
- NCT05357131
- Testing
- Hypnosis without VR (HYP), Hypnosis with VR (VRH)
- Where
- Belgium
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Liege
Trigeminal Neuralgia
Randomized Study of L-Baclofen in Patients With Refractory Trigeminal Neuralgia
OBJECTIVES: I. Evaluate the efficacy of L-baclofen in patients with refractory trigeminal neuralgia. II. Evaluate the safety and tolerance of L-baclofen in these patients.
- Trial name
- NCT00004431
- Testing
- L-baclofen
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Pittsburgh
Schizophrenia
Brexpiprazole (OPC-34712) Trial in the Treatment of Adults With Acute Schizophrenia
The purpose of this study is to explore changes in efficacy, cognitive functioning, and safety of flexibly-dosed Brexpiprazole monotherapy in subjects with acute schizophrenia
- Trial name
- NCT02054702
- Testing
- Brexpiprazole, Aripiprazole
- Volunteers
- 97 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Schizophrenia
Open-label Study to Compare Hospitalization Rates of Schizophrenic Patients Treated With Oral Antipsychotics Versus IM Depot Aripiprazole
The purpose of this study is to compare retrospective hospitalization rates of schizophrenic patients treated with oral antipsychotics to prospective hospitalization rates of these patients treated with IM depot aripiprazole.
- Trial name
- ARRIVE- EU (NCT01509053)
- Testing
- Aripiprazole (Abilify®) IM Depot Injection, Oral aripiprazole
- Where
- 10 sites in Belgium, Bulgaria and 1 more
- Volunteers
- 30 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Stroke, Cognitive Deficits
Self Treatment With an Electronic Device for Cognitive Rehabilitation in Patients With Subacute Stroke
The objective of this study is to evaluate whether the independent use of an electronic device by a patient with stroke outcomes can enhance the effectiveness of rehabilitative treatment for attentional functions compared to…
- Conditions
- Stroke, Cognitive Deficits, Computerized Rehabilitation, Computerized Device
- Trial name
- NCT06755437
- Testing
- Rehabilitation with a computerized device (in the morning), Self-treatment with a computerized device (in the afternoon), self-treatment with pencil-and-paper exercises (in the afternoon)
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Universita di Verona
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