Clinical trials: Psychological Disorders
Attention Deficit Hyperactivity Disorder
The Effect of Methylphenidate on Decision-making Ability of Attention Deficit Hyperactivity Disorder (ADHD) Adults
The aim of the study is to assess the effect of Methylphenidate on cognitive performance and decision-making ability of ADHD adults, and to compare this effect to the effect on healthy control adults.
- Trial name
- NCT01040702
- Testing
- methylphenidate, sweetener pill
- Where
- Israel
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Shalvata Mental Health Center
Elective Surgery, Postoperative Cognitive Dysfunction
Effect Of Aspirin Preoperative on Postoperative Cognitive Dysfunction In Elderly Patients Undergoing Knee Arthroplasty
Studies have shown that the lifetime risk of developing symptomatic knee osteoarthritis is 40% in men and 47% in women; and the risk can be increased to 60% when the patient's BMI reaches 30 kg/m2.
- Conditions
- Elective Surgery, Postoperative Cognitive Dysfunction, Knee Arthroplasty
- Trial name
- NCT04225702
- Where
- China
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Xuzhou Medical University
Alzheimer's Disease, Dementia With Lewy Bodies
Study Evaluating Intepirdine (RVT-101) on Gait and Balance in Subjects With Dementia
This study seeks to evaluate the effect of intepirdine (RVT-101) on gait and balance in patients with Alzheimer's Disease, Dementia with Lewy Bodies or Parkinson's Disease Dementia.
- Conditions
- Alzheimer's Disease, Dementia With Lewy Bodies, Parkinson's Disease Dementia
- Trial name
- NCT02910102
- Testing
- RVT-101 35 mg
- Where
- 11 sites in United States
- Volunteers
- 38 people
- Sponsor
- Axovant Sciences Ltd.
Older Adults, Healthy Aging
danceSing Care Evaluation: Testing the Effectiveness
This pilot randomised controlled trial aims to compare the effectiveness of a 12-week music and movement intervention in older adults in care homes compared to a waitlist control group.
- Conditions
- Older Adults, Healthy Aging, Aging, Quality of Life
- Trial name
- NCT05601102
- Testing
- danceSing Care
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Stirling
Schizophrenia and Related Disorders
Role of an E-cigarette on Smoking Displacement in Smokers With Schizophrenia
It is well established in the scientific literature that people with schizophrenia smoke tobacco cigarettes at rates up to three times that of the general population, relapse more frequently, and die an average of 25 years…
- Trial name
- NCT03075202
- Testing
- e-cigarette, brand name JUUL
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Weill Medical College of Cornell University
Smoking Cessation, Nicotine Addiction
Circuitry-Guided Smoking Cessation in Schizophrenia
In a double-blinded, randomized, parallel controlled design, patients with schizophrenia spectrum disorder will be exposed to active or sham repetitive transcranial magentic stimulation (TMS) which was guided by functional…
- Conditions
- Smoking Cessation, Nicotine Addiction, Schizophrenia
- Trial name
- NCT03281629
- Testing
- Active TMS stimulation
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Maryland, Baltimore
Erectile Dysfunction, Penile Prosthesis; Complications, Infection or Inflammation
Irrisept vs Traditional Antibiotic Irrigation for Virgin Penile Prosthesis Placement
The purpose of this study is to assess whether intraoperative irrigation with Irrisept is not inferior to irrigation with multiple antibiotics during placement of a first time inflatable penile prosthesis device.
- Trial name
- NCT06489431
- Testing
- Chlorhexidine, Gentamicin, Rifampin
- Where
- 3 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Depression, Major Depressive Disorder
The Efficacy of Automated Feedback After Internet-based Depression Screening
The DISCOVER randomized controlled trial is designed to evaluate the effect of automated feedback after internet-based depression screening in individuals with undetected depression.
- Trial name
- DISCOVER (NCT04633096)
- Testing
- tailored feedback of depression screening results, standardized feedback of depression screening results
- Where
- Germany
- Volunteers
- 1,178 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Lung Cancer, Tobacco Use Disorder
Biomarkers for Early Detection of Lung Cancer in Patients With Lung Cancer, Participants at High-Risk for Developing Lung Cancer, or Healthy Volunteers
RATIONALE: Collecting and storing samples of sputum and tissue to study in the laboratory may help doctors identify biomarkers related to cancer.
- Trial name
- NCT00899262
- Testing
- immunohistochemistry staining method, laboratory biomarker analysis, sputum cytology
- Where
- 2 sites in United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- South West Wales Cancer Institute
Critical Illness
Multi-component Family Support Tool Intervention (FST)
The National Academy of Medicine and the National Institutes of Health have called for urgent action to improve the care delivered to the nearly 1,000,000 older Americans who die in intensive care units (ICUs) annually or survive…
- Trial name
- FST (NCT05019261)
- Testing
- Multi-component Family Support Intervention
- Where
- 7 sites in United States
- Volunteers
- 1,039 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Alzheimer's Disease, Dementia
A Study of Acupuncture for Patients With Behavioural and Psychological Symptoms of Dementia
The purpose of the study is to evaluate the safety and tolerability of acupuncture for patients with BPSD \& healthy volunteers.
- Trial name
- NCT01055561
- Testing
- Acupuncture
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Stellate Ganglion Block
Effects of Stellate Ganglion Block on Delirium and Circadian Rhythm in Geriatric Intensive Care Patients
Delirium is a common complication in elderly intensive care unit (ICU) patients and is associated with poor clinical outcomes. Circadian rhythm disruption is considered an important contributing factor in delirium development.
- Trial name
- NCT07558642
- Testing
- stellate ganglion block with 0.5% bupivacaine
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Antalya Training and Research Hospital
Parkinson Disease, REM Sleep Behavior Disorder (iRBD)
Role of Slow Waves in the Progression of Neurodegeneration in Isolated REM Sleep Behavior Disorder
This study tests whether enhancing deep sleep with gentle sounds at night can slow progression in people with iRBD or early Parkinson's disease. Participants wear a sensor headband and headphones for 18 months.
- Trial name
- SloW-iRBD (NCT07355842)
- Testing
- Tosoo Axora
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- University of Zurich
Depressive Episode, Major Depressive Disorder
Pre-mapping Networks for Brain Stimulation 2
The investigators compare the primary and secondary outcome measures using accelerated intermittent theta burst stimulation (aiTBS, 20 sessions active and 20 sessions sham in a counterbalanced crossover design) to treat…
- Trial name
- PreNeSt2 (NCT05260086)
- Testing
- Neuronavigated aiTBS
- Where
- Germany
- Volunteers
- 92 people
- Sponsor
- University Medical Center Goettingen
Diabetes Mellitus, Type 2, Binge-Eating Disorder
Type 2 Diabetes and Binge Eating Disorder (BED)
The goal of this research project is to improve the treatment of individuals living with both type 2 diabetes (T2D) and Binge Eating Disorder (BED).
- Trial name
- NCT06325670
- Testing
- BED treatment, Waitlist
- Where
- Denmark
- Volunteers
- 34 people
- Sponsor
- Odense University Hospital
Opiate Addiction, Borderline Personality Disorder
Evaluation of DBT Compared to Drug Counseling for Opiate Addicts
The purpose of this study is to compare a one year treatment program of Dialectical Behavior Therapy (DBT) + suboxone for opiate addicted individuals meeting criteria for borderline personality disorder (BPD) to a one year…
- Trial name
- NCT00117741
- Testing
- Dialectical Behavior Therapy, Drug Counseling
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- University of Washington
Cognitive Impairment, Cognitive Flexibility
The Effects of Single Exercise Sessions on Cognitive Flexibility and Brain Functional Connectivity in Older Adults With Cognitive Impairment
Objectives: To investigate the effects of different forms (physical and mental, aerobic and resistance) of single exercise on the cognitive flexibility and brain functional connectivity of elderly individuals with cognitive…
- Trial name
- NCT07623954
- Testing
- EXERCISE TRAINING, health education materials
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai University of Sport
Parkinson's Disease
A Standardized Meditation Technique "Body-scan", in the Management of Anxiety in Hospitalized Parkinsonian Patients
The aim of the study is to constitute a proof of concept study for a larger study investigating the effect of mindfulness on anxiety and agitation in Parkinson's disease (PD) based on the results of a preliminary feasibility.
- Trial name
- PARAM2A (NCT03349554)
- Testing
- body-scan meditation, Psychological evaluation
- Where
- France
- Volunteers
- 33 people
- Sponsor
- University Hospital, Bordeaux
Breast Cancer
mHealth Usage Among Nigeria Women Diagnosed With Breast Cancer Receiving Chemotherapy
The research is studying the effect of a mHealth psychoeducational intervention on self-efficacy, coping and psychological distress of Nigerian women diagnosed with breast cancer receiving chemotherapy The study is a two-arm…
- Trial name
- NCT05489354
- Testing
- mHealth psychoeducational intervention
- Where
- 2 sites in Nigeria
- Volunteers
- 126 people
- Sponsor
- Chinese University of Hong Kong
Diagnosis, Psychiatric
Learning Diagnostic Skills Online (German: Diagnostik Skills Online Lernen)
Clinical psychologists give diagnoses to their patients everyday and these diagnoses determine if and how these patients will be treated. Misdiagnoses can have severely adverse effects.
- Trial name
- DiSkO (NCT05294094)
- Testing
- blended learning, teaching format as usual
- Where
- 3 sites in Germany
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Ruhr University of Bochum
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