Clinical trials: Psychological Disorders
Dementia, Alzheimer Disease
Effects of a Multicomponent Exercise Intervention on Physical and Cognitive Function of Older Adults With Dementia
Dementia is a leading cause of death and disability that was declared as one of the greatest health and social care challenges of the 21st century.
- Conditions
- Dementia, Alzheimer Disease, Vascular Dementia, Neurocognitive Disorders
- Trial name
- Body&Brain (NCT04095962)
- Testing
- Exercise
- Where
- Portugal
- Volunteers
- 110 people
- Sponsor
- Universidade do Porto
Mental Health
Mental Health After Dexmedetomidine for Electrical Storm
The goal of the research study is to measure mental health and quality of life indices of individuals treated for electrical storm (ES).
- Trial name
- NCT07368062
- Testing
- Dexmedetomidine
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Problem Behaviors, Attention Deficit Hyperactivity Disorder
Mental Health Services for Foster and Adopted Children
This study will determine the effectiveness of a relationship-based intervention in improving the interaction between caregivers and young children placed in their care.
- Conditions
- Problem Behaviors, Attention Deficit Hyperactivity Disorder, Depression
- Trial name
- NCT00056303
- Testing
- Attachment and Biobehavioral Catch-up, Developmental Education for Families
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- University of Delaware
Alzheimer Disease
Digital Twins for Model-driven Non-invasive Electrical Brain Stimulation
The purpose of this study is to obtain preliminary data in advance of a larger clinical trial designed to test whether repeated, daily sessions of at-home transcranial alternating current stimulation (tACS) can lead to a…
- Trial name
- NEUROTWIN (NCT06826261)
- Testing
- transcranial alternating current stimulation
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Patiens in Early Stage of Chemotherapy
Laughter Yoga- Integrated Virtual Reality Nature Exploration in Early Stage of Chemotherapy
After obtaining informed consent, pre-test applications will be performed on participants in the experimental and control groups following randomization, and information regarding treatment plans will be recorded.
- Trial name
- NCT07798661
- Testing
- laughter yoga-integrated virtual reality
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ataturk University
Separation Anxiety Disorder, Social Anxiety Disorder
Effectiveness Study of CBT for Anxiety in Children
The study aims to evaluate the effectiveness of a cognitive behaviour therapy program (FRIENDS) for anxiety disorders in children aged 8-15 years who have been referred to child and adolescent mental health clinics in Western…
- Conditions
- Separation Anxiety Disorder, Social Anxiety Disorder, Generalized Anxiety Disorder
- Trial name
- ATACA (NCT00586586)
- Testing
- Cognitive behavioural therapy
- Where
- Norway
- Volunteers
- 222 people
- Sponsor
- Haukeland University Hospital
Depression in Old Age, Depression, Anxiety
Internet Delivered Psychotherapy for Older Adults
The goal of this mixed-methods, single-arm intervention study is to develop and evaluate a new internet-delivered psychotherapy option called Ger-iPST in older adults with symptoms of depression.
- Trial name
- NCT05739370
- Testing
- Problem-Solving Therapy for Older Adults
- Where
- Canada
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Borderline Personality Disorder
Measuring the Impact of Real Time fMRI Neurofeedback in Borderline Personality Disorder
This study will test the impacts of real time fMRI neurofeedback in patients with Borderline Personality Disorder. This is a pilot study in a small number of people enrolled in clinical programs at Yale New Haven Hospital.
- Trial name
- NCT04306341
- Testing
- real time fMRI neurofeedback
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Yale University
Schizophrenia
Aripiprazole IM Depot for Chinese Patients With Schizophrenia
This study assess pharmacokinetics and safety of single-administration of Aripiprazole IM Depot formulation at doses of 300 and 400mg in patients with schizophrenia.
- Trial name
- NCT03287505
- Testing
- Aripiprazole IM Depot
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Otsuka Beijing Research Institute
Dementia
Reminiscence Therapy in Individuals With Dementia
This research will be carried out with the aim of determining the effect of reminiscence therapy applied to individuals with dementia on cognitive functions, anxiety, depression and activities of daily living.
- Trial name
- NCT06180694
- Testing
- Reminiscence therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Amasya University
Alcoholism, Alcohol Abuse
Zonisamide vs. Placebo in the Treatment of Alcohol Dependence
This is a pilot study designed to examine the potential efficacy and tolerability of zonisamide compared to placebo for the treatment of alcohol dependence.
- Conditions
- Alcoholism, Alcohol Abuse, Alcohol Dependence
- Trial name
- NCT00595556
- Testing
- zonisamide
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- UConn Health
Hereditary Spastic Paraplegia, Neurodegenerative Diseases
Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)
The purpose of the HSP Sequencing Initiative is to better understand the role of genetics in hereditary spastic paraplegia (HSP) and related disorders.
- Conditions
- Hereditary Spastic Paraplegia, Neurodegenerative Diseases, Pediatric Disorder, Spasticity, Muscle
- Trial name
- NCT05354622
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Boston Children's Hospital
Opioid Use Disorder, Cognitive Ability General
Older Adults, Methadone, and Cognitive Function
The increasing prevalence of opioid use disorder (OUD) among older adults, coupled with high overdose rates and cognitive impairments associated with opioid use, highlights a critical gap in addiction treatment.
- Trial name
- NCT07153029
- Testing
- Smartphone based cognitive tasks
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Maryland, Baltimore
Alcoholism
Individually Adapted Therapy of Alcoholism
The primary objective is to directly compare the efficacy of acamprosate, naltrexone and placebo for relapse prevention in alcoholics.
- Trial name
- NCT00317031
- Testing
- Acamprosate or Naltrexone
- Where
- 5 sites in Germany
- Volunteers
- 435 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Alcohol Use Disorder
Donepezil and Cognitive Training for Alcohol Use Disorder (AUD)
The goal of the project is to evaluate whether donepezil + cognitive remediation therapy is superior to placebo in reducing heavy drinking in patients with alcohol use disorder in a double-blind, placebo-controlled trial.
- Trial name
- NCT05042102
- Testing
- Donepezil + Cognitive remediation therapy (CRT)
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- VA Connecticut Healthcare System
Autistic Disorder, Autism, Early Infantile
Using the Digital EEG Spectral Analysis in Assessing Neuroelectrical Processing Abnormalities in Autism
Individuals with Autism Spectrum Disorder will have abnormal DESA® results. Our objective is to use neuroelectrical measures to determine the degree of processing abnormalities in individuals with Autism.
- Conditions
- Autistic Disorder, Autism, Early Infantile, Autism, Infantile, Asperger Syndrome
- Trial name
- NCT00693953
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Yellen & Associates, Inc.
Stress
Copeptin During a Standardized Psychological Stress Test
The aim of the PsyCo Study is to determine whether psychological Stress has an influence on copeptin levels.
- Trial name
- PsyCo (NCT01866137)
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Fatigue Intensity, Sleep
MorphECOS - Evaluation of the Influence of Fatigue and Sleep on the Performance of 2nd Cycle Medical Students (OSCE)
Objective and Structured Clinical Examinations (OSCEs) has been incorporated recently in the certification process as a final national undergraduate ranking examination. This exam is a challenge for medical students.
- Conditions
- Fatigue Intensity, Sleep, Sleep Deprivation, Circadian Rhythm
- Trial name
- MorphECOS (NCT06952972)
- Where
- France
- Volunteers
- 619 people, healthy volunteers welcome
- Sponsor
- Claude Bernard University
Disorders, Substance Related
A Study on the Effects of Breathing Exercises and Aerobic Exercise on the Health of Men in Drug Rehabilitation
This study aims to investigate the effects of an 8-week combined exercise program on male individuals in drug rehabilitation. The program integrates resistance-based breathing training with aerobic exercise.
- Trial name
- NCT07592195
- Testing
- Resistance Breathing Training, Aerobic Exercise
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Southwest Medical University
Treatment-resistant Schizophrenia
SMART Design to Compare Antipsychotic Treatments in Treatment-Resistant Schizophrenia
The project intends to take treatment-resistant schizophrenia as the research object and uses sequential multiple assignment randomized trial(SMART) design to define the treatment recommendations of different drug regimen for…
- Trial name
- NCT04528095
- Testing
- Clozapine, MECT, DBS
- Where
- China
- Volunteers
- 162 people
- Sponsor
- Shanghai Mental Health Center
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