Clinical trials: Psychological Distress
Depression - Major Depressive Disorder, Psychological Distress
Testing a Non-Deceptive Placebo Intervention for Subclinical Depressive Symptoms
Subclinical depression - depressive symptoms that fall below the threshold for major depressive disorder - is common in young adults and predicts later depressive episodes, yet it often goes untreated.
- Conditions
- Depression - Major Depressive Disorder, Psychological Distress, Depression / Major Depressive Disorder
- Trial name
- NDP_CCG (NCT07889908)
- Where
- United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Miami University
Psychological Distress, Psychological Well-being
Two Sessions of Coach-Delivered Core Transformation for Distress and Well-Being
The goal of this study is to learn if Core Transformation, a guided coaching process, lowers psychological distress in adults. It will also look at well-being, daily functioning, and whether any changes last over time.
- Trial name
- NCT07879196
- Testing
- Core Transformation Process
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Andreas NLP (Legal Entity - Real People Press)
Mental Health, Parenting / Maternal Behavior
Healing Hearts: A Mindfulness App for Parents Navigating Divorce or Separation
This study examines online programs for parents navigating divorce or separation. Researchers will study whether a self-guided mindfulness app called Healing Hearts, followed by a self-guided online parenting program called the…
- Conditions
- Mental Health, Parenting / Maternal Behavior, Parenting Anxiety, Parenting Behavior
- Trial name
- NCT07871916
- Testing
- Healing Hearts, electronic New Beginnings Program, Curated internet resources
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Breast Cancer Female, Psychological Distress
The Breast Cancer Survivors and Partners Online Research Together (SUPORT) Project
Many breast cancer survivors (estimated 70% in some studies) experience clinically significant depression and/or anxiety in the months and years after finishing cancer treatments.
- Trial name
- NCT05676255
- Testing
- Cognitively-Based Compassion Training for Survivors, Cognitively-Based Compassion Training for Dyads, Health Education
- Where
- United States
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Anxiety, Hospitalization
Virtual Nature Versus Guided Imagery for Anxiety and Well-Being in Hospitalized Older Adults
Long hospital stays can be difficult for older adults. Being confined to a ward, with limited mobility and little access to the outdoors, may contribute to anxiety, low mood, and reduced well-being.
- Conditions
- Anxiety, Hospitalization, Quality of Life, Psychological Distress
- Trial name
- NCT07765355
- Testing
- Immersive virtual reality nature exposure, Guided imagery
- Where
- 2 sites in Hungary
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Psychological Distress
Meditation to Reduce Firefighter Distress
The more than one million firefighters in the United States provide critical emergency medical services in communities they serve and are on the front lines of healthcare delivery, including in the post-pandemic world.
- Trial name
- NCT06518616
- Testing
- 10-day meditation intervention, 10-day health education intervention
- Where
- United States
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Psychological Distress
Ensemble Programme an Early Intervention for Informal Caregivers of Psychiatric Patients
This study focuses on the difficulties of maintaining optimal psychological health and quality of life for caregivers in adult psychiatry while they play an important role in helping patients with severe psychiatric disorders.
- Trial name
- Ensemble (NCT04020497)
- Testing
- Ensemble programme, SAU
- Where
- Switzerland
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Institut et Haute Ecole de la Santé la Source
Physiological Conditions, Distress, Emotional
Hand in Hand: Feasibility of a Compassion-Focused App to Support Parents of Children With Mental Health Problems
Parents of children and adolescents with mental health problems may experience substantial caregiving burden and emotional distress, including persistent stress, self-criticism, shame, and parental burnout.
- Conditions
- Physiological Conditions, Distress, Emotional, Caregiving Stress, Burnout
- Trial name
- NCT07840404
- Testing
- App-based Compassion Program
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Depression, Anxiety
Efficacy of a Brief Intervention to Improve Sexual and Gender Minorities' Mental Health: Randomized Controlled Trial.
Experiences of violence, from micro to physical aggressions, have a deleterious impact on mental health. According to the Minority Stress Theory, unfavorable social conditions (such as anticipated and experienced discrimination…
- Conditions
- Depression, Anxiety, Psychological Distress, Social Phobia
- Trial name
- ESCREVA-SE (NCT05349877)
- Testing
- Expressive writing, Self-affirmation
- Where
- Brazil
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Stress, Psychological, Occupational, Stress, Psychological
Self-Help Plus (SH+) for Stress Reduction in Social Service Workers: A Pilot RCT
This is a two-arm, stratified cluster-randomized controlled pilot trial evaluating the feasibility and preliminary effectiveness of the World Health Organization's Self-Help Plus (SH+) intervention for stress reduction among…
- Conditions
- Stress, Psychological, Occupational, Stress, Psychological, Psychological Distress, Burnout, Professional
- Trial name
- NCT07644949
- Testing
- Self-Help Plus (SH+), Enhanced Care as Usual (ECAU)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Psychological Distress, Depressive Symptoms
Nature Photography for Mental Well-Being and Nature Connectedness in Young Adults
This study tests whether a nature photography intervention can improve mental well-being and nature connectedness in young adults with mild emotional distress, and examines self-compassion as a key mechanism in this process.
- Conditions
- Psychological Distress, Depressive Symptoms, Anxiety Symptoms
- Trial name
- NCT07803367
- Testing
- Nature-Based Mindful Photography, Human-Made Object Photography, Self-Guided Digital Stress Management Handbook
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Beijing Normal University
Preterm Labor, Maternal Psychological Distress
Fetal Brain Growth - Pilot Study
The goal of this observational prospective study is to explore the feasibility of measuring fetal and neonatal brain growth using 2D and 3D ultrasound in fetuses exposed to threatened preterm labor (TPTL) and antenatal…
- Trial name
- NCT05994443
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Psychological Distress, Psychological Wellbeing
Italian YOLO: A Web-Based ACT Mental Health Promotion Intervention for University Students
The mental health of university students requires urgent attention, as many students are exposed to increased risk of psychological distress, including symptoms of depression, anxiety, academic stress, and reduced well-being.
- Conditions
- Psychological Distress, Psychological Wellbeing, Academic Stress
- Trial name
- YOLO (NCT07654569)
- Testing
- Italian YOLO
- Where
- Italy
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Bologna
Alcohol Use Disorder, Drug Use
A Hybrid Effectiveness Implementation Study of Latino/a Alcohol and Drug Users
Alcohol use is a significant problem among Latinxs and immigration-related stress increases risk for substance use. A theoretically-based cultural adaptation of motivational interviewing (CAMI) that specifically integrated…
- Conditions
- Alcohol Use Disorder, Drug Use, Psychological Distress
- Trial name
- CAMI-HI (NCT04771650)
- Testing
- CAMI
- Where
- 2 sites in United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Post Traumatic Stress Symptoms, Psychological Distress
Effectiveness of Cognitive Behavioral Intervention for Trauma in Schools (CBITS): A Study With Pakistani Adolescents
This study will evaluate whether a school-based counseling program, Cognitive Behavioral Intervention for Trauma in Schools (CBITS), helps reduce trauma-related symptoms and improve psychological functioning in adolescents in…
- Conditions
- Post Traumatic Stress Symptoms, Psychological Distress, Trauma Exposure
- Trial name
- NCT07768540
- Testing
- cognitive behavioral intervention for trauma in schools
- Where
- Pakistan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National University of Modern Languages
Mental Health, HIV
"Gwan Enjoy Life:" A Peer-Supported Mental Health Mentoring Intervention to Improve Engagement in Care Among Sexual Minority Men Living With HIV in Jamaica
Sexual minority men (SMM) in Jamaica face many challenges that affect their health and well-being. Although they make up a relatively small part of the population, they are much more likely to be living with HIV than the general…
- Conditions
- Mental Health, HIV, Pyschological Distress, Suicidal Ideation
- Trial name
- GwanEnjoyLife (NCT07762612)
- Testing
- Gwan Enjoy Life Interveniton
- Where
- Jamaica
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Gut Microbiota, Psychological Distress
Effects of Grape Powder on Psychological Distress and Gut Microbiota in College Students
The goal of this trial is to investigate the effect of freeze-dried table grape powder (FTGP) on psychological distress and gut microbiota in college students.
- Trial name
- NCT07214428
- Testing
- freeze-dried table grape powder
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Psychological Distress, Academic Stress
A Single-Arm Trial of a Web-Based Acceptance and Commitment Therapy Mental Health Promotion Intervention for University Students
University students experience high rates of psychological distress and frequently encounter barriers to accessing professional mental health support.
- Trial name
- YOLO UQ (NCT07701330)
- Testing
- YOLO intervention: 4-week web-based intervention
- Where
- Australia
- Volunteers
- 626 people, healthy volunteers welcome
- Sponsor
- The University of Queensland
Psychological Distress, Genetic Testing
Psychological Support and Psycho-Emotional Trajectories in Cancer Genetics.
Undergoing a cancer genetic testing pathway and receiving results regarding a personal or familial cancer predisposition can generate substantial, multifaceted psycho-emotional distress for patients.
- Conditions
- Psychological Distress, Genetic Testing, Hereditary Neoplastic Syndromes, Neoplasms
- Trial name
- PsyOncoGen (NCT07695506)
- Testing
- Patients undergoing their first cancer genetic testing consultation who choose to utilise the clinical psychological support offered by the unit, Patients undergoing their first cancer genetic testing consultation who choose to follow the care pathway without utilising the systematically offered clinical psychological support.
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Vicarious Trauma, Psychological Distress
Efficacy of Vicarious Post-Traumatic Growth Intervention for Nurses in Emergency Units
This randomized controlled trial aims to evaluate the efficacy of a Vicarious Post-Traumatic Growth (VPTG) Intervention among nurses working in emergency units.
- Conditions
- Vicarious Trauma, Psychological Distress, Post-Traumatic Growth, Psychological, Psychological Well-being
- Trial name
- VPTG-RCT (NCT07677527)
- Testing
- Psychoeducational Vicarious Post-Traumatic Growth Intervention
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fatima Jinnah Women University