Clinical trials: Psychological Wellbeing
PTSD, Depression
Local Participatory Systems Dynamics to Increase Reach of Evidence Based Addiction and Mental Health Care
The most common reasons Veterans seek VA addiction and mental health care is for help with opioid and alcohol misuse, depression and PTSD.
- Conditions
- PTSD, Depression, Alcohol Use Disorder, Opioid Use Disorder
- Trial name
- NCT04356274
- Testing
- Participatory System Dynamics (PSD), Audit and Feedback (AF)
- Where
- United States
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Palo Alto Veterans Institute for Research
Stress Resilience, Blood-Brain Barrier Integrity
Role of the Blood-Brain Barrier in Stress Resilience: Investigating New Pathways Towards Pharmacological Augmentation of Stress Resilience
The goal of this clinical trial is to better understand the relationship between blood-brain barrier (BBB) function and stress resilience and to investigate a potential causal role for BBB function in stress resilience in humans.
- Conditions
- Stress Resilience, Blood-Brain Barrier Integrity, Mental Health
- Trial name
- PHASR-PP (NCT06965868)
- Testing
- Metformin
- Where
- 3 sites in Germany, Poland and 1 more
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Leibniz-Institut für Resilienzforschung (LIR) gGmbH
Mental Wellbeing
MDMA-Assisted Therapy for Mental Healthcare Providers
This is a phase 1, open-label study to assess changes in mental well-being following MDMA administration within a therapeutic setting, in mental health providers who are in training to become MDMA assisted therapists.
- Trial name
- NCT07102576
- Testing
- MDMA Hydrochloride
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rachel Yehuda
Mental Health, PTSD
Further Development and Initial Testing of RESTORE in Frontline Workers
There is considerable need for psychological intervention targeting stressor-related mental health symptoms related to COVID-19.
- Conditions
- Mental Health, PTSD, Anxiety, Depressive Symptoms
- Trial name
- RESTORE (NCT04873622)
- Testing
- RESTORE: Recovering from Extreme Stressors Through Online Resources and E-health
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Mental Health, Cognition
Short-term Effect of Glucose and Sacharose Ingestion on Cognitive Performance and Mood in Elderly
The objective of the current study is to determine the acute effect of a glucose drink and a sacharose drink compared to a placebo on cognitive performance in elderly with light memory complaints.
- Conditions
- Mental Health, Cognition, Memory, Attention
- Trial name
- NCT01427231
- Testing
- glucose, sacharose
- Where
- Netherlands
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Depression, Depressive Disorder
Evaluation of the Naturalistic User Experience of the Website "ich Bin Alles @Schule" (i Am Everything @school)
The aim of this study is to investigate the naturalistic user experience and acceptance of the German website "ich bin alles @Schule".
- Conditions
- Depression, Depressive Disorder, Depression in Children, Depression in Adolescence
- Trial name
- NCT06668688
- Testing
- "ich bin alles @Schule" (i am everything @school; www.schule.ich-bin-alles.de)
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Metabolic Disease, Mental Health Wellness 1
Healthy Early Life Moments in Singapore
This study aims to assess whether an integrated continuum of care from the preconception period, across maternity until the first 18 months of life, can promote maternal metabolic and mental health, as well as offspring health…
- Conditions
- Metabolic Disease, Mental Health Wellness 1, Lifestyle Risk Reduction, Maternal Obesity
- Trial name
- HELMS (NCT05207059)
- Testing
- HELMS Lifestyle Intervention
- Where
- Singapore
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Parenting Practices, Intimate Partner Violence (IPV)
Effects of a Financial Literacy and Gender-Transformative Couples Intervention on Parenting Practices in India
Many families in India experience intimate partner violence (IPV) and financial stress, both of which can harm the way parents interact with and discipline their children.
- Conditions
- Parenting Practices, Intimate Partner Violence (IPV), Mental Health, Empowerment
- Trial name
- NCT07651670
- Testing
- Let us Grow Together: Economic Wellbeing for Families
- Where
- 4 sites in India
- Volunteers
- 4,552 people, healthy volunteers welcome
- Sponsor
- Shruti Shukla
Mental Health and General Well-being
The Influence of Mindfulness on the Link Between Consumer Culture Values and Well-being
The study is a three-arm intervention, where students are randomly assigned to one of three conditions: Teacher-led group-based MBCT, Self-guided MBCT using an audio book, or 'wait list' control.
- Trial name
- NCT03079154
- Testing
- Teacher-led MBCT course, Self-guided MBCT course
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Sussex
Art, Wellness, Psychological
The Singapore Art-Health Study
The goal of the Singapore Art-Health RCT is to examine the effect of a standardized 12-week museum -based participatory art program on health condition, well-being, and quality of life in older community dweller, one that adheres…
- Conditions
- Art, Wellness, Psychological, Frailty, Quality of Life
- Trial name
- NCT05945589
- Testing
- Singapore A-Health Intervention
- Where
- Singapore
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Yoga, Yoga Exercises
Yoga Asana Chandra Harmoni on Psychological Well-being and Learning Readiness Among Medical Students
The goal of this trial is to learn if the Yoga Asana Chandra Harmoni intervention can improve psychological well-being and learning readiness in medical students.
- Conditions
- Yoga, Yoga Exercises, Well Being, Self Efficacy
- Trial name
- NCT07171268
- Testing
- Yoga Asana Chandra Harmoni
- Where
- Indonesia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Gadjah Mada University
Mental Health
Family Mental Health Family Navigator Project (FMHN)
This study will focus on developing and testing a family-based mental health navigator intervention, the Family Mental Health Navigator (FMHN), to evaluate whether the intervention combined with mHealth is preliminary efficacious…
- Trial name
- FMHN (NCT04822636)
- Testing
- Family-based mental health navigation
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Mental Health, HIV
"Gwan Enjoy Life:" A Peer-Supported Mental Health Mentoring Intervention to Improve Engagement in Care Among Sexual Minority Men Living With HIV in Jamaica
Sexual minority men (SMM) in Jamaica face many challenges that affect their health and well-being. Although they make up a relatively small part of the population, they are much more likely to be living with HIV than the general…
- Conditions
- Mental Health, HIV, Pyschological Distress, Suicidal Ideation
- Trial name
- GwanEnjoyLife (NCT07762612)
- Testing
- Gwan Enjoy Life Interveniton
- Where
- Jamaica
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Burnout, Professional
Effect of Coaching on Mid-Career Physician Well-Being, Job Satisfaction, and Fulfillment
The study will assess the effect of individualized professional coaching for mid-career family medicine and general internal medicine physicians on burnout, job satisfaction, and professional fulfillment.
- Trial name
- NCT03207581
- Testing
- Professional Coaching
- Where
- 3 sites in United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Earthquake, Mental Health Issue
The Effect of Relaxation Techniques on Earthquake Survivors
The aim of this study is to investigate the effect of relaxation and breathing exercises on individuals experiencing post-earthquake stress-related symptoms.
- Trial name
- NCT06013280
- Testing
- Progresive Muscle Relaxation and Breathing Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Depressive Symptomatology, Psychological Distress
The COVID-19 Pandemic and Exercise Study
The COPE Trial is a randomized controlled trial that will provide currently isolated yet generally physically healthy 18-64 year old adults who are pre-retirement with the opportunity to receive a free 3-month subscription to…
- Conditions
- Depressive Symptomatology, Psychological Distress, Health Behavior
- Trial name
- COPE (NCT04400279)
- Testing
- Yoga group, High Intensity Interval Training group, Combination
- Where
- Canada
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Lifestyle, Healthy, Sleepiness
Lifestyle Coaching for Fatigue Mitigation in Emergency Medicine Residents
The purpose of this study is to determine whether personalized lifestyle coaching minimizes the negative impact of circadian disruption on performance and recovery in emergency medicine physician trainees during night shifts.
- Conditions
- Lifestyle, Healthy, Sleepiness, Alertness, Shift-Work Related Sleep Disturbance
- Trial name
- NCT06015646
- Testing
- Personalized lifestyle coaching and educational handout, Handout
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Stanford University
Colorectal Cancer
Exploratory Analysis on the Impact of Morbidities on Colorectal Cancer Screening Uptake
The primary aim of this project is to examine the association between having a long-term condition (morbidity) and screening uptake for colorectal cancer.
- Trial name
- NCT02503969
- Testing
- Exposure to having a long-term condition.
- Where
- United Kingdom
- Volunteers
- 8,776 people, healthy volunteers welcome
- Sponsor
- University of Sheffield
Mental Health Wellness 1
Counting On U: Towards Better Mental Health
The financial state of a business and the mental health of the business owner are closely related. Thus, the devastating impact of COVID-19 on businesses means small-medium enterprises (SMEs) owners are particularly vulnerable to…
- Trial name
- NCT04982094
- Testing
- Mental Health First Aid and Relationship Building Training, Mental Health First Aid
- Where
- Australia
- Volunteers
- 1,599 people, healthy volunteers welcome
- Sponsor
- Leanne Saxon
Nausea and Vomiting in Pregnancy
Guided Imagery for Nausea and Well-Being in Pregnant Women
This study aims to evaluate the effect of a guided imagery-based psychoeducational intervention on nausea and vomiting severity and psychological well-being in pregnant women.
- Trial name
- GI-PREG (NCT07544095)
- Testing
- Guided Imagery-Based Psychoeducation
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Inonu University
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