Clinical trials: Psychology
Multiple Sclerosis
Self-Directed Positive Psychology Intervention for Newly Diagnosed Multiple Sclerosis
The goal of this clinical trial is to learn whether positive psychology (PP) exercises such as writing a letter of gratitude or remembering a past success can help individuals with newly diagnosed multiple sclerosis (MS) to feel…
- Trial name
- NCT06891937
- Testing
- Positive psychology
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Brigham and Women's Hospital
Antibody-mediated Rejection, Humoral Rejection
Efficacy and Safety of Eculizumab for Treatment of Antibody-mediated Rejection Following Renal Transplantation
This is an open-label analysis that will compare eculizumab versus Plasmapheresis (PP) and Immunoglobulin (IVIg) for the treatment of antibody-mediated rejection (AMR) in renal transplant recipients.
- Trial name
- NCT01895127
- Testing
- Eculizumab, Immunoglobulin, Plasmapheresis
- Where
- 3 sites in United States
- Volunteers
- 11 people
- Sponsor
- Brigham and Women's Hospital
Cancer Survivors, African Americans
Grateful Strides Toward Physical Activity and Well-Being for Black Breast Cancer Survivors
This pilot study will assess the feasibility of a gratitude intervention to promote physical activity, and well-being and positively impact biomarkers of health among older African American breast cancer survivors.
- Conditions
- Cancer Survivors, African Americans, Women, Psychology, Positive
- Trial name
- NCT05473026
- Testing
- Gratitude Intervention
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Florida
Cardiac Transplant Disorder
Don't Throw Your Heart Away: Layperson Study 1
Publicly available outcome assessments for transplant programs do not make salient that some programs tend to reject many of the hearts they are offered, whereas other programs accept a broader range of donor offers.
- Trial name
- NCT04133831
- Testing
- Total Survival, Stratified Transplant Survival
- Where
- United States
- Volunteers
- 1,019 people, healthy volunteers welcome
- Sponsor
- Carnegie Mellon University
Mental Well-being, Happiness
Joyful Parenting Pilot Project RCT Study
Aims: To enhance mental well-being of adolescents, adults and their families by creating a positive, happy and joyful environment in the community. Targets: Parents aged 12-59 and their family members in Hong Kong.
- Trial name
- NCT03282071
- Testing
- Joyful Parenting Intervention
- Where
- 2 sites in Hong Kong
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Congestive Heart Failure, Emotions
Researching Emotions And Cardiac Health: Phase III
The focus of this study is to examine the feasibility, acceptability, and preliminary impact of a 12-week, telephone-delivered, positive psychology (PP)-based health behavior intervention in a group of patients with mild to…
- Conditions
- Congestive Heart Failure, Emotions, Patient Compliance
- Trial name
- REACH III (NCT03220204)
- Testing
- PP-based health behavior intervention, MI-based educational control condition
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Massachusetts General Hospital
Stress Disorders, Post-Traumatic, Depressive Symptoms
Treatment for Veterans With Military Sexual Trauma
The purpose of this study is to evaluate the effectiveness of Cognitive Processing Therapy (CPT) versus Present-Centered Therapy (PCT) in treating current post-traumatic stress symptoms associated with sexual assault that…
- Conditions
- Stress Disorders, Post-Traumatic, Depressive Symptoms, Anxiety Symptoms, Quality of Life
- Trial name
- NCT00371644
- Testing
- Cognitive Processing Therapy, Present-Centered Therapy
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- US Department of Veterans Affairs
Opioid Abuse
AESOPS Trial 2 (AESOPS-2): Availability of Opioid Harm
The opioid epidemic is the largest man-made public health crisis the United States has faced. The objective of Trial 2 of the Application of Economics \& Social psychology to improve Opioid Prescribing Safety (AESOPS-2) study, is…
- Trial name
- AESOPS-2 (NCT04758637)
- Testing
- Overdose Notification
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- University of Southern California
Kidney Failure, Chronic
Induction Therapy Study in Live Donor Kidney Transplant Recipients With a Positive Crossmatch
The purpose of this study is to determine whether the anti-T cell antibody, Thymoglobulin is a more effective induction medication than the anti-IL-2R inhibitor daclizumab, in kidney transplant recipients who have a positive…
- Trial name
- NCT00275509
- Testing
- Thymoglobulin, Daclizumab, Plasmapheresis
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Johns Hopkins University
Major Depressive Disorder, Hepatitis C, Chronic
Efficacy and Safety of Escitalopram for Prevention of Depression Induced by Peg-Interferon in Hepatitis C Patients
The purpose of this study is to determine whether the use of an antidepressant (escitalopram) can prevent depressive episodes that appear during the treatment with peg-interferon and ribavirin in patients with chronic hepatitis C.
- Trial name
- NCT00166296
- Testing
- Escitalopram
- Where
- 15 sites in Spain
- Volunteers
- 133 people
- Sponsor
- Germans Trias i Pujol Hospital
Stress (Psychology)
Mobile Self-Management Program for Stress Reduction in Young Adults
The goal of this clinical trial is to learn if a mobile self-management program that combines Positive Psychology (PP) and Behavioral Activation (BA) helps reduce stress in young adults in South Korea.
- Trial name
- NCT07174544
- Testing
- Mobile Self-Management Program integrated with Positive Psychology and Behavioral Activation
- Where
- South Korea
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- The Catholic University of Korea
Lung Transplant Failure and Rejection
Assessment of Donor Derived Cell Free DNA and Utility in Lung Transplantation
The use of Allosure to identify and quantify circulating donor-derived cell-free DNA to quantitate allograft injury in the early post-transplant period and determine its relationship to allograft failure.
- Trial name
- NCT04318587
- Testing
- Allosure
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Pablo Sanchez
Breast Cancer, Psychology, Social
Effectiveness of Screening and Brief Interventions for Alcohol and Tobacco During Breast Cancer Treatment (ONKODETOX)
Despite scientific, clinical and political incentives, alcohol and/or tobacco screening and brief intervention (SBI) services are poorly implemented in oncology settings.
- Trial name
- ONKODETOX (NCT03371732)
- Testing
- Motivational Intervention group, Educational advises group
- Where
- France
- Volunteers
- 104 people
- Sponsor
- Institut Bergonié
Renal Transplant Rejection
Imaging Kidney Transplant Rejection Using Ferumoxytol-Enhanced Magnetic Resonance
The goal of this study is to develop a non-invasive imaging test for in vivo detection of kidney transplant rejection. The hypotheses are that 1) Ferumoxytol-MRI can generate accurate estimates of tissue iron concentrations and…
- Trial name
- NCT02006108
- Testing
- Feraheme, MRI-GE Healthcare 3 Tesla magnet
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Stanford University
ACS - Acute Coronary Syndrome
Positive Psychology for Acute Coronary Syndrome Patients
This is a randomized controlled pilot trial in approximately 50 acute coronary syndrome patients to determine if a 12 week, telephone-delivered, combined positive psychology-motivational interviewing intervention is feasible and…
- Trial name
- PEACE-IV (NCT03122184)
- Testing
- Positive Psychology + Motivational Interviewing, Motivational Interviewing Health Education
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Massachusetts General Hospital
Middle Aged
Text Messaging to Increase Activity in Midlife
This is a randomized controlled pilot trial of a text message intervention to promote physical activity in midlife adults (MASTERY), compared to an attention-matched control condition.
- Trial name
- MASTERY (NCT04849052)
- Testing
- MASTERY, Attentional Control
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Massachusetts General Hospital
Kidney Transplant Failure and Rejection
Comparison of the Cognitive and Motor Effects of Treatment Between an Immediate- and Extended-release Tacrolimus (Envarsus® XR) Based Immunosuppression Regimen in Kidney Transplant Recipients
The primary objective is to compare the effect of treatment with an immediate-release tacrolimus to an extended-release tacrolimus (i.e., Envarsus® XR) immunosuppressive regimen on cognitive and motor function in kidney…
- Trial name
- NCT03437577
- Testing
- immediate-release tacrolimus, extended release tacrolimus
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Minnesota
Congestive Heart Failure, Emotions
Researching Emotions And Cardiac Health (REACH): Phase II
The focus of this study is to examine the feasibility, acceptability, and preliminary impact of our customized positive psychology (PP)-based health behavior intervention in a group of patients with mild to moderate heart failure…
- Conditions
- Congestive Heart Failure, Emotions, Patient Compliance
- Trial name
- REACH II (NCT02938052)
- Testing
- PP-based health behavior intervention
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Massachusetts General Hospital
Cancer, Exercise
How Easy-to-Follow Exercises Can Help Cancer Patients With Anxiety While Receiving Chemotherapy
Cancer is one of the main causes of death, and this study looks at how light exercise and stretching might reduce anxiety in patients receiving chemotherapy.
- Conditions
- Cancer, Exercise, Stress
- Trial name
- NCT06943638
- Testing
- Mild Exercise and stretches
- Where
- Greece
- Volunteers
- 45 people
- Sponsor
- Christine Mavrogiannopoulou
Tinnitus
Cognitive Behavioral Therapy (CBT) for Tinnitus
This study examined how useful it is to teach veterans coping skills for dealing with tinnitus, also called ringing in the ears.
- Trial name
- NCT00724152
- Testing
- Cognitive Behavioral Therapy, Tinnitus Education
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- US Department of Veterans Affairs