Clinical trials: Psychoses, Traumatic
Depression Disorders, Bipolar Affective Disorder
Epidemiological Study on the Prevalence of Mental Disorders in Slovakia
This study maps the current epidemiological situation of mental disorders in Slovakia. The aim of the study is to determine the prevalence of selected mental disorders in the adult population of the Slovak Republic, assess the…
- Conditions
- Depression Disorders, Bipolar Affective Disorder, Generalized Anxiety Disorder (GAD), Panic Disorder
- Trial name
- EpiMentDisSK (NCT07129408)
- Where
- Slovakia
- Volunteers
- 3,100 people, healthy volunteers welcome
- Sponsor
- Comenius University
Mental Disorder, Post-traumatic Stress Disorder
Empathy in Post-traumatic Stress Disorder in Comparaison to a Control Population
It has been shown in the literature that the symptoms of post-traumatic stress disorder influence the quality of life of patients, in particular through the cognitive alterations they can cause.
- Conditions
- Mental Disorder, Post-traumatic Stress Disorder, Empathy
- Trial name
- NCT05617781
- Testing
- Questionnary
- Where
- France
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Psychotic Disorders, Psychiatric Hospitalization
Youth Experiences and Health Study
This study aims to identify unusual experiences and psychiatric symptoms that indicate a heightened risk for severe mental disorders - especially psychoses.
- Conditions
- Psychotic Disorders, Psychiatric Hospitalization, Prodromal Symptoms, Cannabis Use
- Trial name
- YEAH (NCT03332966)
- Testing
- Psychiatric questionnaires, Semi-structured psychiatric interview
- Where
- 3 sites in Finland
- Volunteers
- 1,000 people
- Sponsor
- Finnish Institute for Health and Welfare
Psychosis, Complex Post-Traumatic Stress Disorder
Psychological Interventions for Complex PTSD And Schizophrenia-Spectrum Disorder: PICASSO Trial
Psychosis is a highly distressing mental health condition, affecting up to 3% of the population. Conceptually, it has much in common with complex post-traumatic stress disorder (CPTSD), a recently introduced condition in ICD-11.
- Conditions
- Psychosis, Complex Post-Traumatic Stress Disorder, Schizophrenia
- Trial name
- PICASSO (NCT05281640)
- Testing
- Affect Dysregulation intervention, Negative Self Concept intervention, Disturbed Relationships intervention
- Where
- 2 sites in United Kingdom
- Volunteers
- 57 people
- Sponsor
- Edinburgh Napier University
Major Depressive Disorder, Bi-Polar Disorder
DELPhI Evaluation of Psychiatric Conditions
DELPhI acquisition and analysis software, a QuantalX Neuroscience development, which is designed to measure, analyze, and display brain electrical activity of human electroencephalogram (EEG), to transcranial magnetic stimulation…
- Conditions
- Major Depressive Disorder, Bi-Polar Disorder, ADHD, Schizophrenia
- Trial name
- NCT03842345
- Sponsor
- QuantalX Neuroscience
PTSD, Stress Disorders, Traumatic
Psilocybin for the Treatment of Veterans With Post-Traumatic Stress Disorder
The primary aim of this study is to assess the safety and efficacy of psilocybin-assisted therapy in the treatment of post-traumatic stress disorder in United States military Veterans.
- Conditions
- PTSD, Stress Disorders, Traumatic, Stress Disorders, Post-Traumatic, Trauma and Stressor Related Disorders
- Trial name
- NCT05554094
- Testing
- Psilocybin
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Ohio State University
Schizophrenia Disorders, Personality Disorders
Recovery in Telling Life Stories
This project tests the Recovery In Telling Life Stories (RETELL) intervention, aimed at supporting personal recovery in people with severe mental illness (SMI).
- Conditions
- Schizophrenia Disorders, Personality Disorders, Obsessive - Compulsive Disorder, Anxiety Disorders
- Trial name
- RETELL (NCT07082777)
- Testing
- Narrative therapy
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Aarhus
Schizophreniform Disorders, Bipolar Disorder
REWRITALIZE Your Recovery - Evaluation of a Creative Writing Group Intervention
Health institutes call for psychosocial interventions and recovery-oriented approaches as supplement to pharmacological treatment for mental health disorders.
- Conditions
- Schizophreniform Disorders, Bipolar Disorder, Severe Depression, Ptsd
- Trial name
- REWR (NCT06251908)
- Testing
- Rewritalize, Standard mental health care
- Where
- 6 sites in Denmark
- Volunteers
- 300 people
- Sponsor
- Amager Hospital
Adjustment Disorders, Mental Disorder
Transdiagnostic Behavior Therapy Vs TAU for Adjustment Disorder Following Traumatic Event Exposure
Adjustment Disorder (AjD) is the most common mental health condition diagnosed in Active Duty personnel, and is diagnosed following an extreme stress event such as traumatic loss of a comrade, serious accident or injury, or other…
- Trial name
- NCT06433271
- Testing
- Transdiagnostic Behavior Therapy (TBT), Treatment as Usual-Problem Solving Therapy (TAU-PST)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- The University of Texas Health Science Center, Houston
Psychotic Disorders, Stress Disorders, Traumatic
Psychotherapy for Psychosis, Adverse Events, and Substance Misuse
People with psychosis have significantly higher rates of adversity (e.g., abuse) and substance misuse (i.e., problematic drug and alcohol use) than people with other mental illnesses.
- Conditions
- Psychotic Disorders, Stress Disorders, Traumatic, Substance Use
- Trial name
- NCT04546178
- Testing
- Prolonged exposure (PE)+ therapy, Treatment as usual (TAU)
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- Nova Scotia Health Authority
Post Traumatic Stress Disorder, PTSD
Effectiveness of Trauma Therapy Using Prolonged Exposure for Patients With PTSD and a Comorbid Psychotic Disorder
Psychosis patients with comorbid PTSD will be treated with trauma therapy.
- Conditions
- Post Traumatic Stress Disorder, PTSD, Psychosis
- Trial name
- TEP (NCT06048172)
- Testing
- Prolonged Exposure
- Where
- Germany
- Volunteers
- 56 people
- Sponsor
- Medicalschool Hamburg
Post Traumatic Stress Disorder, Schizophrenia
PTSD (PostTraumatic Stress Disorder) Services for Veterans With SMI (Severe Mental Illness)
As in the general population, there is no clear standard of care within Veterans Affairs Medical Centers for treating posttraumatic stress disorder (PTSD) among individuals with severe mental illness (SMI).
- Conditions
- Post Traumatic Stress Disorder, Schizophrenia, Schizoaffective Disorder, Bipolar Disorder
- Trial name
- PTSD/SMI (NCT01542229)
- Testing
- Prolonged Exposure for PTSD (PE) + Treatment as Usual (TAU), Treatment As Usual (TAU)
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- VA Office of Research and Development
Psychiatric Diagnosis, Schizophrenia Disorders
The Key to Integrated Trauma Treatment in Psychosis Trial
Schizophrenia spectrum disorders (SSDs) have a significant trauma etiology: trauma has been reported in 65 - 80% in this patient group and have a negative impact on prognosis.
- Conditions
- Psychiatric Diagnosis, Schizophrenia Disorders, Psychological Trauma, Historical
- Trial name
- KIT (NCT06608706)
- Testing
- Eye Movement Desensitization and Reprocessing (EMDR) for psychosis
- Where
- 11 sites in Norway
- Volunteers
- 187 people
- Sponsor
- Haukeland University Hospital
Schizophrenia, PTSD
Schizophrenia and PTSD Project: Health, Interventions, and Risk/Resilience Evaluation(SAPPHIRE Study)
We propose to establish a database characterizing the presence or absence of comorbid PTSD in veterans with schizophrenia or schizoaffective disorder (SAD) receiving services at the Durham VA Medical Center.
- Trial name
- SAPPHIRE (NCT00560677)
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Durham VA Medical Center
Post Traumatic Stress Disorder, Alcohol Use Disorder
FAAH Availability in Psychiatric Disorders: A PET Study
The aim of the present study is to examine Fatty Acid Amide Hydrolase (FAAH) availability in humans, including healthy individuals and across a spectrum of psychiatric disorders in which alterations in the endocannabinoid system…
- Conditions
- Post Traumatic Stress Disorder, Alcohol Use Disorder, Psychosis
- Trial name
- NCT04404712
- Testing
- [11C]MK-3168
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Yale University
Psychiatric Disorders, Depression - Major Depressive Disorder
Implementing Action-Based Cognitive Remediation for Transdiagnostic Cognitive Difficulties in a Tertiary Mental Health Hospital
Psychiatric conditions are each defined by different set of symptoms, however, they often share common characteristics such as impairments in cognitive and social functioning.
- Conditions
- Psychiatric Disorders, Depression - Major Depressive Disorder, Schizophrenia and Other Psychotic Disorders, Anxiety and Mood Disorders
- Trial name
- NCT07506070
- Testing
- Action-Based Cognitive Remediation
- Volunteers
- 160 people
- Sponsor
- The Royal Ottawa Mental Health Centre
Trauma, Psychological, Psychosis
A Comprehensive Third-generation Intervention for People With Psychosis and Post-traumatic Stress Symptoms
Existing data suggest that both trauma and Post-Traumatic Stress Disorder (PTSD) are very common among individuals with psychosis.
- Trial name
- IITG-PPT (NCT05619822)
- Testing
- TAU + A comprehensive third-generation intervention, TAU
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Universidad Complutense de Madrid
Schizophrenia, Schizoaffective
Psychiatric Advance Directives for Improved Mental Health Care
During a psychiatric crisis, persons with severe mental illness (SMI) confront complex challenges concerning treatment choices and are often ill equipped or unable to make mental health care decisions.
- Conditions
- Schizophrenia, Schizoaffective, Bipolar Disorder, Stress Disorders, Post-traumatic
- Trial name
- NCT00105794
- Testing
- Psychiatric Advance Directives intervention
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- US Department of Veterans Affairs
Cognitive Function 1, Social
Social Cognition Assessment in Young Adults
The primary objective of this study is to determine the efficacy and feasibility of a battery of neuropsychological measures evaluating social cognition and behavior in young adults diagnosed with schizophrenia, autism spectrum…
- Trial name
- NCT02922400
- Testing
- Social Cognition Assessment and Training
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Stroke, Traumatic Brain Injury
Pragmatic Assessment and Treatment for the Health System
The project goal is to promote a feasible and effective approach to communicative disorders in neurological and psychiatric populations, focused on the pragmatics of language.
- Conditions
- Stroke, Traumatic Brain Injury, Schizophrenia
- Trial name
- PATHS (NCT05809401)
- Testing
- Pragmatic Rehabilitation, Neuropsychological Rehabilitation
- Where
- 4 sites in Italy
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- IRCCS San Camillo, Venezia, Italy