Clinical trials: Psychosis NOS
Alzheimer's Disease Psychosis
ACP-204 in Adults With Alzheimer's Disease Psychosis Open Label Extension Study
This 52-week, open-label extension study is to evaluate the long-term safety and tolerability of ACP-204 in subjects with ADP.
- Trial name
- NCT06194799
- Testing
- ACP-204
- Where
- 76 sites in United States, Brazil and 10 more
- Volunteers
- 752 people
- Sponsor
- ACADIA Pharmaceuticals Inc.
Schizophrenia
Inpatient Evaluation of Adults With Schizophrenia
The purpose of this study is to understand the biologic basis of schizophrenia and to determine which symptoms are related to the illness itself and which are related to medications used to treat the illness.
- Trial name
- NCT00001247
- Testing
- Sirolimus
- Where
- United States
- Volunteers
- 648 people
- Sponsor
- National Institute of Mental Health (NIMH)
Psychomotor Agitation, Acute Disease
IMPACT: A Study to Explore the Efficacy and Safety of Paliperidone ER in Patients With Acute Agitation
This study will investigate the effect of paliperidone ER (in combination with or without benzodiazepines) in patients presenting with symptoms of agitation and/or aggression in the context of psychosis, and will generate data…
- Trial name
- NCT01050478
- Testing
- Paliperidone ER, Benzodiazepine
- Where
- 14 sites in Belgium
- Volunteers
- 56 people
- Sponsor
- Janssen Cilag N.V./S.A.
Bipolar Affective Disorder
Effect of Regulated Add -on Sodium Chloride Intake on Stabilization of Serum Lithium Concentration in Bipolar Disorder
Bipolar affective disorder or manic -depressive psychosis (MDP) is a mood disorder affecting 2.4% of the global population . Lithium is considered as the "gold standard" for the treatment of bipolar disorder but the clinical use…
- Trial name
- NCT04222816
- Testing
- Lithium Carbonate, Sodium chloride
- Where
- India
- Volunteers
- 60 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
First-episode Psychosis
HIIT in Patients With a First-episode Psychosis
This study aims to estimate the effect of a 3-month High Intensity Interval Training on antipsychotic-induced weight gain in patients with a first episode of psychosis, as well as to determine whether these effects are maintained…
- Trial name
- NCT04792476
- Testing
- High Intensity Interval Training
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Intervención Temprana en Psicosis de Cantabria (ITPCan)
Psychosis
A Combined Aerobic and Resistance Training Program for Adults With Psychotic Disorders
The study is a feasibility study of a combined high intensity aerobic and strenght exercise program for persons with psychotic disorders.
- Trial name
- TREPP (NCT05719116)
- Testing
- Physical exercise
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Solli Distriktspsykiatriske Senter
Depressive Disorder, Major, Bipolar Disorder
Psychiatric Genotype/Phenotype Project Repository
The purpose of this project is to obtain DNA, brain imaging data, other biological samples (e.g., urine, serum), and a comprehensive clinical assessment on patients with schizophrenia and other psychotic disorders, bipolar…
- Conditions
- Depressive Disorder, Major, Bipolar Disorder, Psychotic Disorders
- Trial name
- PGPP (NCT00762866)
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Psychotic Disorders, Stress Disorders, Traumatic
Psychotherapy for Psychosis, Adverse Events, and Substance Misuse
People with psychosis have significantly higher rates of adversity (e.g., abuse) and substance misuse (i.e., problematic drug and alcohol use) than people with other mental illnesses.
- Conditions
- Psychotic Disorders, Stress Disorders, Traumatic, Substance Use
- Trial name
- NCT04546178
- Testing
- Prolonged exposure (PE)+ therapy, Treatment as usual (TAU)
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- Nova Scotia Health Authority
Psychosis of Childhood Borderline, Psychotic Disorder
Study of Self-Recognition and Self/Other Distinction Disorders in Patients With Psychological Vulnerability
The main objective of this study is to establish whether there are differences in self-recognition and self/other distinction in subjects with psychological vulnerability compared to healthy volunteer controls.
- Trial name
- ALTER-EGO (NCT04945278)
- Testing
- Double mirror device ALTER-EGO, EASE test
- Where
- France
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Acute Psychosis
Acceptance & Commitment Therapy for Psychotic Inpatients
The overarching aim of the research project is to investigate whether Acceptance \& Commitment Therapy (ACT) is an efficacious psychotherapeutic method of treatment for inpatients suffering from acute psychosis.
- Trial name
- NCT02458105
- Testing
- Acceptance & Commitment Therapy, Attention
- Where
- Sweden
- Sponsor
- Uppsala University
Schizophrenia, Psychosis
Early Detection of Respiratory Disorders in Psychosis
This study aims to evaluate the presence of lung function impairment in a sample of patients diagnosed with non-affective psychosis.
- Conditions
- Schizophrenia, Psychosis, Chronic Respiratory Disease
- Trial name
- NCT03476473
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Fundación Marques de Valdecilla
Schizophrenia
Cost-effectiveness of Interventions in First-episode Psychosis
Schizophrenia has very significant economic consequences. Costs fall on many different parts of society, especially on individuals with schizophrenia and their families.
- Trial name
- PAFIPEC (NCT02916303)
- Where
- Spain
- Volunteers
- 490 people
- Sponsor
- Fundación Marques de Valdecilla
Prodromal Schizophrenia, Psychotic Disorders
Psychosis: Early Detection, Intervention and Prevention
The primary aim of this application is to conduct a randomized, controlled clinical trial of a specialized mental health service delivery system specifically developed for prodromal psychotic disorders.
- Conditions
- Prodromal Schizophrenia, Psychotic Disorders, Severe Bipolar Disorder With Psychotic Features, Severe Major Depression With Psychotic Features
- Trial name
- EDIP (NCT01597141)
- Testing
- Family-aided Assertive Community Treatment, Enhanced standard treatment
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- MaineHealth
Psychosis, Substance Use Disorders
Clozapine Versus Olanzapine as Treatment for Comorbid Psychotic Disorder and Substance Use Disorder
The purpose of this trial is to determine if patients with comorbid psychotic disorder and substance use disorder will continue in treatment longer if treated with clozapine than with olanzapine, and will have greater reductions…
- Trial name
- NCT03857581
- Testing
- Clozapine, Olanzapine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Augusta University
Insomnia, Psychosis
CBT-I to Improve Functional Outcomes in Veterans With Psychosis
The goal of this project is to examine the efficacy of Cognitive Behavioral Therapy for Insomnia (CBT-I) for improving sleep and related functional outcomes in Veterans with psychosis and insomnia.
- Trial name
- CBT-I Merit (NCT04646200)
- Testing
- Cognitive Behavioral Therapy-Insomnia, Health and Wellness
- Where
- 2 sites in United States
- Volunteers
- 152 people
- Sponsor
- VA Office of Research and Development
Cannabis, Psychotic Disorders
Cannabinoids, Neural Synchrony, and Information Processing
The study examines the effects of delta-9-tetrahydrocannabinol (Δ9-THC), the principal active ingredient of cannabis, on neural synchrony. Neural synchrony is studied using electroencephalography (EEG).
- Trial name
- THC-Gamma (NCT00708994)
- Testing
- THC
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Yale University
Schizophrenia, Psychosis
Study of Immunotherapy in Autoantibody Positive Psychosis
Psychosis is a mental health problem that causes people to perceive or interpret things differently from those around them, often involving hallucinations or delusions.
- Conditions
- Schizophrenia, Psychosis, Auto Immune Disorders
- Trial name
- SINAPPS-1 (NCT02449746)
- Testing
- Plasma Exchange, Intravenous immunoglobulin
- Where
- 5 sites in United Kingdom
- Volunteers
- 10 people
- Sponsor
- University of Cambridge
Psychosis
mHealth for Psychosis Help-seeking
The proposed study research project aims to develop and test a mobile health intervention designed to improve the wellness of young people at risk for psychosis and facilitate users' engagement with treatment and thus reduce…
- Trial name
- NCT05905601
- Testing
- NORTH "Full", NORTH "Lite"
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Washington
Schizophrenia, Schizoaffective Disorder
Mediators and Moderators of Treatment Outcome in Recent-Onset Psychosis
Multifamily group psychoeducation [MFG] and group cognitive behavioral therapy [GCBT] are evidence-based treatments for first episode psychosis.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Bipolar Disorder With Psychotic Features, Major Depression With Psychotic Features
- Trial name
- NCT01570972
- Testing
- Group Cognitive Behavioral Therapy, Multifamily Group Psychoeducation
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- University of Arizona
Psychotic Disorders
VR-assisted CBT for Adolescents With Psychosis
Psychotic disorders typically emerge during late adolescence or early adulthood. Patients, who are diagnosed with a psychotic disorder before turning 18 years, are defined as early onset psychosis patients (EOP).
- Trial name
- NCT04586868
- Testing
- An intervention development study, A randomized feasibility study, A single-case study
- Where
- Norway
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital