Clinical trials: Psychotropic Drugs
Psychotropic Drugs
ORiginal meThodology for Assessing the Impact of the Coronavirus Health Crisis on Psychotropic Drug Use
The health crisis linked to the coronavirus has had a significant impact on the mental health. The question of the repercussion of this crisis on the consumption of psychotropic drugs is crucial.
- Trial name
- TORNADO (NCT05395897)
- Where
- France
- Volunteers
- 2,772,093 people
- Sponsor
- Nantes University Hospital
Dementia
Effects of Involvement in a Group-based Creative Expression Program on Psychotropic Drug Use in Persons With Dementia
This project, a small-scale pilot study, will attempt to determine if involvement in a group-based creative expression program may correlate with a reduction in use of psychotropic drugs for persons with dementia.
- Trial name
- NCT01382693
- Testing
- TimeSlips, Standard care activity program
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Milton S. Hershey Medical Center
Cognitive Symptom, Depression
Psychotropic Drug Use in the Elderly Living in Nursing Homes and the Influence of a Structured Drug Review
The overall aim of this study is to explore if a structured drug review will change clinical symptoms and the psychotropic drugs prescription rate in the elderly living in nursing homes (participants of the study).
- Conditions
- Cognitive Symptom, Depression, Anxiety, Neuropsychiatric Syndrome
- Trial name
- NCT03736577
- Testing
- Drug reviews with NorGeP-NH
- Where
- Norway
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Ostfold Hospital Trust
Eating Disorders, Mood Disorders in Children and Adolescents
Psychotropic-Drug-induced QT Prolongation and ECG Monitoring in the Pediatric Population
Electrocardiogram (ECG) Q-T prolongation is a cardiac electrophysiological disorder associated with the occurrence of arrhythmias potentially fatal.
- Conditions
- Eating Disorders, Mood Disorders in Children and Adolescents, Psychotic Disorder, QTc Intervals Changes
- Trial name
- NCT06870006
- Where
- 6 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Meyer Children's Hospital IRCCS
Psychiatric Disorder, Adolescent Behavior
Mental Health and Sexuality in Adolescents and Young Adults
According to the World Health Organization (WHO), "Sexual health is a state of physical, emotional, mental and social well-being in relation to sexuality, not merely the absence of disease, dysfunction or of infirmity.
- Conditions
- Psychiatric Disorder, Adolescent Behavior, Mental Health Issue
- Trial name
- SEX-T-ADO (NCT05316948)
- Testing
- self-questionnaire
- Where
- 12 sites in France
- Volunteers
- 770 people
- Sponsor
- Fondation Santé des Étudiants de France
Psilocybin, Hallucinogens
Pilot Study: Effects of Psilocybin on Behavior, Psychology and Brain Function in Long-term Meditators
This is a pilot study to finalize methods for a larger study being planned for the future. This research is being done to characterize performance of tasks, brain functioning, and the effects of psilocybin in individuals with a…
- Conditions
- Psilocybin, Hallucinogens, Pharmacologic Actions, Central Nervous System Agents
- Trial name
- NCT01988311
- Testing
- psilocybin
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Substance Withdrawal Syndrome
Abuse and Addiction in ICU
Investigators are seeking to determine the impact of recent alcohol, smoking or psychotropic drug use prior to intensive care unit (ICU) admission on incidence of delirium and sedation requirements.
- Trial name
- NCT02951793
- Testing
- AUDIT-C, Smoking history, Prior psychotropic medication use
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Seoul National University Hospital
Major Depressive Disorder
A Study of LY03005 vs Pristiq
The objective of this study is to evaluate relative bioavailability between 80 mg LY03005 oral tablets and 50 mg Pristiq® oral tablets after a single dose of each drug in a cross-over 2-period design under fasting condition in…
- Trial name
- NCT03733574
- Testing
- LY03005, Pristiq
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Luye Pharma Group Ltd.
Schizophrenia
Safety and Efficacy of Cariprazine in Schizophrenia
The objective of this study is to evaluate the efficacy, safety, and tolerability of cariprazine relative to placebo for the treatment of acute exacerbation of schizophrenia.
- Trial name
- NCT01104779
- Testing
- Cariprazine
- Where
- 41 sites in United States, Colombia and 2 more
- Volunteers
- 446 people
- Sponsor
- Forest Laboratories
Nicotine Dependence, Substance Abuse
Randomized Trial of Ultrashort Psychotherapy vs Sustained-Release Bupropion for Smoking Cessation
Background Smokers often reject drugs as smoking cessation aids. Nonpharmacological interventions are notoriously under-evaluated.
- Conditions
- Nicotine Dependence, Substance Abuse, Substance Dependence, Tobacco Dependence
- Trial name
- NCT00484692
- Testing
- sustained-release bupropion (Zyban(R)), Psychodynamic Model Training (R) = PDM(R)
- Where
- Austria
- Volunteers
- 779 people
- Sponsor
- Medical University Innsbruck
Psychotic Disorders
Effect of Antipsychotics on Appetite Regulation
The purpose of this study is to evaluate changes in appetite-regulating hormones, body composition (weight, body fat%), and hunger ratings in persons early in treatment with one of four atypical antipsychotic medications…
- Trial name
- ADAPT (NCT00903916)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of North Carolina, Chapel Hill
Nicotine Withdrawal, Marijuana Dependence
Medications Development for the Treatment of Cannabis Related Disorders
The primary objective of this application is to test the neurobehavioral mechanisms and effects of aprepitant as a new cessation agent for cannabis, tobacco or both.
- Conditions
- Nicotine Withdrawal, Marijuana Dependence, Cannabis Dependence, Nicotine Dependence
- Trial name
- MTC (NCT01204723)
- Testing
- Active Aprepitant
- Where
- 2 sites in United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Xerostomia
Development of a Milk Product Substitution for Patients Suffering From Xerostomia Caused by Medication
Dry mouth is in most cases due to iatrogenic causes, particularly drugs. The existing products such as saliva substitutes are often disappointing (bad taste, poor efficiency).
- Trial name
- LactoXeros (NCT01960101)
- Testing
- LactoXeros, Aequasyal
- Where
- 2 sites in France
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
COVID-19
COVID-19 & Psychiatry: A Retrospective Chart Review
A retrospective chart review study to determine the effects of psychotropic medications and prior psychiatric diagnoses on COVID-19 patients' disease progression, and severity.
- Trial name
- NCT05244096
- Testing
- No intervention
- Where
- United States
- Volunteers
- 65,000 people
- Sponsor
- Northwestern University
Deprescriptions, Antidepressive Agents
Patient-centred Deprescribing of Psychotropic, Sedative and Anticholinergic Medication in Elderly Patients With Polypharmacy
The PARTNER study is a multicentre, two-arm, pragmatic cluster-randomised trial evaluating the impact of a focused and patient-centred cooperation between general practitioners (GPs) and community pharmacists (PARTNER…
- Conditions
- Deprescriptions, Antidepressive Agents, Antipsychotic Agents, Analgesics, Opioid
- Trial name
- PARTNER (NCT05842928)
- Testing
- PARTNER intervention, Control intervention
- Where
- 3 sites in Germany
- Volunteers
- 352 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Schizophrenia
A Long-Term Study of MP-214 in Patients With Receiving Multiple Drugs Schizophrenia
The objective of this study is to evaluate the long-term safety, tolerability, and efficacy of MP-214 in patients with receiving multiple drugs schizophrenia.
- Trial name
- NCT01626885
- Testing
- MP-214
- Where
- Japan
- Volunteers
- 42 people
- Sponsor
- Tanabe Pharma Corporation
Schizophrenia, Tranquilizing Agents
A Study to Evaluate Treatment Adherence in Schizophrenia With Long Acting Risperidone Microspheres (e-STAR)
This study is a non-interventional web based registry designed to assess demographic, treatment and outcomes data in patients receiving treatment with long-acting injectable risperidone.
- Conditions
- Schizophrenia, Tranquilizing Agents, Mental Disorders, Therapeutic Uses
- Trial name
- NCT00294008
- Testing
- Risperdal Consta
- Volunteers
- 230 people
- Sponsor
- Janssen Korea, Ltd., Korea
Psychiatric Disorders, Pain
Clinical Utility of Pharmacogenomics of Psychotropic Medications
While the scientific understanding of pharmacogenomics is quickly accelerating, its translation to clinical decision-making (especially in psychiatric practice) has progressed more slowly.
- Trial name
- NCT03907124
- Testing
- Genetically-guided treatment with FDA-approved psychotropic drugs, Treatment as usual (TAU)
- Where
- United States
- Sponsor
- Oregon Health and Science University
ADHD, Depression Disorders
Evaluate the Effects of Long-term Use of Psychotropic Medications on Eye Movement Patterns With the Gaize Device
The study aims to verify if the Gaize ocular device can effectively identify eye movements indicative of prescribed psychotropic medication usage by employing Drug Recognition Expert (DRE) testing protocols within a controlled…
- Conditions
- ADHD, Depression Disorders, Mood Disorders, Anxiety Disorder Generalized
- Trial name
- Rx Meds Gaize (NCT07389473)
- Testing
- Prescription Psychotropic Medications
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Gaize
Challenging Behavior, Autism Spectrum Disorder
Measurement of Treatment Effects
The overall objective is to evaluate and compare the efficacy of two common treatments for CB in children and adolescents with autism using multiple outcome measures.
- Trial name
- NCT07024303
- Testing
- Psychotropic medication (at discretion of psychiatrist), Behavioral therapy
- Volunteers
- 20 people
- Sponsor
- Matthew J O'Brien, PhD, BCBA-D