Clinical trials: Psyllium
Constipation
Fiber Regimens for Constipation Symptoms
The objective of the current study is to compare the effects of bowel recipe with psyllium on symptoms associated with constipation.
- Trial name
- constipation (NCT03845673)
- Testing
- Psyllium, Bowel recipe
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Psyllium, Inulin
Exploring Mechanism of Action of Dietary Fibre on the Gut Microbiota and Metabolites
Cancer patients receiving pelvic radiotherapy suffer side effects to the intestine, including diarrhoea and occasionally rectal bleeding, often worsened by chemoradiation.
- Trial name
- MERLIN (NCT05906589)
- Testing
- Inulin, Psyllium, Maltodextrin
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Hunger
Study of Psyllium 6.8 g Versus Placebo on Satiety in Healthy Volunteers
This is a randomized, double-blind, placebo-controlled, 2-treatment, 3-period crossover design study to evaluate the effects of psyllium 6.8 g provided as sugarfree Metamucil fiber supplement powder dissolved in water versus…
- Trial name
- NCT01809925
- Testing
- psyllium fiber 6.8g
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Irritable Bowel Syndrome
Effect of Modified Cellulose on Colonic Fermentation of Inulin
A 3-way randomised cross-over study to test the hypothesis that combining either psyllium or methylcellulose to form a gel incorporating inulin will reduce gas production as compared to inulin given with a placebo, maltodextrin.
- Trial name
- COCOA2 (NCT05911347)
- Testing
- Psyllium, Methylcellulose, Maltodextrin
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Overweight and Obesity, Metabolic Cardiovascular Syndrome
The Effects of Psyllium Seed on Body Weight and Metabolic Syndrome Indicators in Patients with Schizophrenia
The research employs a quasi-experimental design, aiming to enroll 24 hospitalized patients with schizophrenia from 2hospitals in the central region, guided by G Power calculations.
- Conditions
- Overweight and Obesity, Metabolic Cardiovascular Syndrome, Schizophrenia, Disorganized
- Trial name
- NCT06789471
- Testing
- psyllium husk
- Where
- Taiwan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ru-Shin Zhang
Hypercholesterolemia, Cardiovascular Risk Factor
The Effect of Psyllium Fibre on LDL-C, Non-HDL-C, and Apolioprotein-B: A Systematic Review and Meta-analysis
Serum cholesterol is a major modifiable risk factor for cardiovascular disease, which despite considerable reduction in prevalence, remains the leading cause of premature mortality worldwide.
- Trial name
- NCT03346733
- Testing
- Psyllium Fibre
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Irritable Bowel Syndrome
Effect of Pre-dosing With Methylcellulose or Psyllium on Colonic Fermentation of Inulin
The aim for this pilot study is to test the hypothesis that pre-dosing with gel-forming dietary fibres (methylcellulose or psyllium) will alter the colonic fermentation of a model fermentable dietary fibre (Inulin) when delivered…
- Trial name
- COCOA3 (NCT06494137)
- Testing
- inulin
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Colon, Irritable
Effect of Methylcellulose or Psyllium on Fermentation of inUlin Assessed USing MRI
The challenge is to understand how fibre interacts with whole-gut function to alter colonic fermentation of fermentable oligo-di- and mono-saccharides and polyhydric alcohols (FODMAPs).
- Trial name
- RUFUS (NCT06291272)
- Testing
- Psyllium, Methylcellulose, Inulin
- Where
- United Kingdom
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Healthy Men
Study to Evaluate the Effects of Psyllium on Blood Glucose
This is an open label, single use, randomized, 4-period cross-over study. In each period, subjects will receive one of 4 test combinations.
- Trial name
- NCT00888602
- Testing
- 3.4 g psyllium, 6.8 g psyllium, Meal
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Healthy
Ispaghula and Colonic Water Content
Chronic constipation is a phenomenon which affects nearly 20% of the population worldwide. Bulking agents such as ispaghula are used as treatments, but only half of the patients are satisfied with the treatment.
- Trial name
- NCT01805999
- Testing
- 7 g Ispaghula
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Metabolic Disease
Husk Fiber Intervention on Metabolic Health of Centrally Obese School Teachers
A group of 120 school teachers (male=60, female=60) was divided into four subgroups for sixteen weeks of an interventional study. One group was kept in control while the other three groups were assigned intervention.
- Trial name
- NCT06188728
- Testing
- effect of 10 gm psyllium husk fiber twice a day, 30 minutes before breakfast and dinner, Effect of life style modification (Diet, Behavior and physical activity), Combined effect of 10 gm Psyllium husk fiber and lifestyle modification
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Peshawar
Constipation
Comparison of Taste and Palatability in Fiber Supplements
The purpose of this study is to compare 1. taste and 2. texture/palatability of Metamucil orange®, Volcolon® and generic orange psyllium.
- Trial name
- NCT02867917
- Testing
- Volcolon sugar free, Metamucil Orange, Psyllium Orange
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Constipation, Diet Modification
A Study of the Effect of Bran, Psyllium and Nopal on Intestinal Water Content Using Magnetic Resonance Imaging
This study will compare 3 food products (bran, psyllium and nopal) on intestinal water content measured via MRI.
- Trial name
- NOPAL (NCT03263065)
- Testing
- Bran, Nopal, Psyllium
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Bone Volume
Vegetable Ivory Bone Material in Bone Healing Compared to Current Standard Methods of Bone Healing
The purpose of this research study is to evaluate whether a biobased natural vegetable ivory formulation can produce similar or better results compared to the current standard bone healing treatment.
- Trial name
- NCT06548685
- Testing
- Bone Grafting, Vegetable Derived
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Mark Stanczyk
Nutrition, Healthy, Appetitive Behavior
Psyllium-enriched Hamburger Meatballs: Effects on Postprandial Lipidemia, Glycemia, Appetite, and Food Intake
The goal of this clinical trial is to enrich the hamburger meatball with psyllium without impairing its sensory properties and to investigate the effects on acute postprandial lipemia and glycemia, prospective food intake, and…
- Conditions
- Nutrition, Healthy, Appetitive Behavior, Food Preferences, Obesity
- Trial name
- NCT05825963
- Testing
- Psyllium
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ahmet Murat Günal
HIV Infection
Effectiveness of the Diaphragm for HIV Prevention
The purpose of this trial is to determine whether using the diaphragm and a lubricant get can reduce women's risk of acquiring an HIV infection.
- Trial name
- NCT00121459
- Testing
- Ortho All-Flex diaphragm and Replens lubricant gel
- Where
- 3 sites in South Africa, Zimbabwe
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Irritable Bowel
Effect of Rate Of Delivery on Colonic Fermentation of inuliN (EON)
To test whether slowing the rate of delivery of inulin with either psyllium or divided dosing of inulin, will reduce colonic gas production as compared to inulin combined with placebo.
- Trial name
- EON (NCT05619341)
- Testing
- psyllium, inulin
- Where
- United Kingdom
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Irritable Bowel Syndrome
Effect of MethylceIlulose or Psyllium on Fermentation of Inulin Assessed Using a Gas Sensing Capsule
The investigators plan to measure the local (in vivo) production of hydrogen when methylcellulose is ingested, to see if the investigators can show a shift of the site of fermentation to the distal colon.
- Trial name
- REALISTIC (NCT06551948)
- Testing
- psyllium, methylcellulose, maltodextrin
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Cardiovascular Risk Factor, Hypercholesterolemia
The Effect of Viscous Dietary Fibers on LDL-cholesterol
This systematic review and meta-analysis is aimed to assess the effect of commonly consumed viscous fibers on blood lipids including LDL-C, non-HDL-C, and ApoB.
- Trial name
- NCT04133805
- Testing
- viscous fiber
- Where
- Canada
- Volunteers
- 7,845 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Impaired Fasting Glucose
Comparison of Psyllium and Microcrystalline Cellulose on Glycemic Measures in Subjects With Impaired Fasting Glucose
The Purpose of this study is to compare the effects of 2 types of dietary fiber, psyllium and microcrystalline cellulose (MCC), on glycemic measures in subjects with impaired fasting glucose.
- Trial name
- NCT01549600
- Testing
- psyllium, Microcrystalline Cellulose
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble