Clinical trials: Ptosis; Eyelid, Congenital
Ptosis, Eyelid
Evaluation of Intraoperative Lagophthalmos Formula
This is a prospective non-randomized study to evaluate the recent intraoperative lagophthalmos formula method for levator resection in determining postoperative eyelid height in congenital ptosis on Egyptian children.
- Trial name
- NCT04291625
- Testing
- Levator muscle resection
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Menoufia University
Congenital Ptosis
Levator Muscle and Its Aponeurotic Maldevelopment in Congenital Ptosis
this study reports the incidence of levator muscle dysgenesis among patients with simple congenital myogenic ptosis. In addition, the study aims to describ the nature of the dysgenesis, including the gross appearance of the…
- Trial name
- NCT07466706
- Testing
- levator muscle resection
- Where
- Egypt
- Volunteers
- 153 people
- Sponsor
- Assiut University
Lower Eyelid Steatoblepharon (Excess Eyelid Fat)
Phase 2 Study of XAF5 (XOPH5) Ointment for Reduction of Excess Eyelid Fat (Steatoblepharon)
This study will test whether XAF5 (XOPH5) ointment, applied once daily to the lower eyelids for 10 weeks, reduces the prominence of lower eyelid fat in adults with moderate to severe steatoblepharon (excess eyelid fat).
- Trial name
- NCT02230761
- Testing
- XOPH5 Ointment
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Topokine Therapeutics, Inc.
Muscular Dystrophy, Oculopharyngeal, Ptosis
Treatment of Ptosis to Muscular Dystrophy Oculopharyngeal by Myoblast Autologous Graft
Interventional , multicenter , comparative study. One eye receiving the cells and the contralateral eye as a negative control . If effectiveness following review of the primary endpoint and the advice of an independent expert…
- Trial name
- TTT-PT-DOP (NCT02878694)
- Testing
- Myoblast autologous graft
- Where
- France
- Volunteers
- 1 people
- Sponsor
- University Hospital, Caen
Upper Eyelid Dynamics
Upper Eyelid Dynamics in Pediatric Blepharoptosis Using High Speed Videography
Evaluation of the Upper Eyelid Dynamics in Simple Congenital Blepharoptosis before and after Levator Muscle Resection Using High speed Photography
- Trial name
- NCT06976645
- Testing
- Levator muscle resection
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Minia University
Dry Eye Syndrome, Ptosis
The Effect of Eyelid Surgery on Dry Eye - a Prospective Study
The investigators aim to assess the effect of blepharoplasty with or without muller muscle resection on the symptoms of dry eye syndrome.
- Conditions
- Dry Eye Syndrome, Ptosis, Dermatochalasis
- Trial name
- NCT02376556
- Where
- Israel
- Volunteers
- 54 people
- Sponsor
- Sheba Medical Center
Eyelid Movement Disorders, Eyelid Ptosis Congenital
Müller's Muscle as a New Proprioceptive Organ
Objectives: Upper eyelid retraction was believed to be maintained solely by voluntary contraction of the levator palpebrae superioris (LPS) and frontalis muscles, together with involuntary contraction of the sympathetically…
- Trial name
- NCT03396627
- Testing
- pathological examination
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Sheba Medical Center
Blepharoptosis
Management of Severe Congenital Blepharoptosis
Frontalis sling surgery was carried out using Ptose-up under general anaesthesia for patients with severe congenital ptosis.
- Trial name
- NCT04214379
- Testing
- Ptosis surgery
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Minia University
Congenital Ptosis
Clinical Significance of Whitnall Ligament Structure
Prospective clincal study to relate the structure of Whitnall ligament in cases of congenital ptosis to the severety of ptosis and the postoperative results.
- Trial name
- NCT04537169
- Testing
- Levator resection
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Menoufia University
Dermatochalasis, Blepharoptosis
Vibration-Assisted Anaesthesia
Aim of study is to investigate whether a small, non-invasive vibrating device applied to the forehead during local anaesthetic administration reduces the pain of the injection.
- Trial name
- NCT00793988
- Testing
- Vibration-assisted anaesthesia, Switched-off vibrating device
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Ptosis
Levator Muscle Strength Evaluation
The purpose of this study is to assess a new technique of measurement for the levator muscle. this measurement may be applied during a clinical evaluation of eyelid malposition.
- Trial name
- NCT02226016
- Testing
- FG-5000A
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Meir Medical Center
Ptosis, Eyelid, Ptosis; Eyelid, Congenital
Modified Müller's Muscle-conjunctival Resection Internal Ptosis Repair Using Fibrin Glue
Fibrin glue is widely used in ophthalmology for homeostasis and tissue recovery. It is commonly used in ocular surface surgeries such as pterygium removal and conjunctival lesions excisions.
- Conditions
- Ptosis, Eyelid, Ptosis; Eyelid, Congenital, Surgical Procedure, Unspecified
- Trial name
- NCT03392272
- Testing
- Using of Tisseel fibrin glue, Using sutures
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Sheba Medical Center
Blepharoptosis
Liquid Bandage (2-Octyl-Cyanoacrylate) in Upper Lid Blepharoplasty
The aim of this randomized and masked prospective trial is to compare the effectiveness of Liquid Bandage (Octyl-2-Cyanoacrylate) and 6/0 nylon suture as a wound closure device in upper lid blepharoplasty surgery.
- Trial name
- NCT00816270
- Testing
- Bilateral Upper eyelid blepharoplasty
- Where
- Brazil
- Volunteers
- 11 people
- Sponsor
- Federal University of São Paulo
Eyelid Diseases, Ptosis, Eyelid
Telemedicine Follow-up for Routine, Low-Risk Oculoplastic Surgery
The investigators propose utilizing a simple telemedical protocol to allow patients to substitute the first post-operative visit with a remote survey that includes essential post-operative history, vision measurement, and…
- Conditions
- Eyelid Diseases, Ptosis, Eyelid, Blepharoptosis, Dermatochalasis
- Trial name
- NCT04235803
- Testing
- Telemedicine follow-up
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- University of California, San Francisco
Ptosis
A Prospective Cohort Study on Visual Function and Psychological Conditions Before and After Surgery for Congenital Ptosis
The goal of this observational study is to learn about the 6-month effects of Levator Resection combined with Fascial Sheath Suspension surgery in patients who undergo this procedure to treat congenital ptosis.
- Trial name
- NCT07534436
- Where
- China
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Congenital Ptosis
Research on Precision Diagnosis and Treatment Decision of Common Eye Diseases Based on Artificial Intelligence
The goal of this observational study is to investigate the clinical features of congenital ptosis in children by analyzing eyelid movement captured through smartphone videos.
- Trial name
- NCT07078552
- Testing
- ptosis
- Where
- China
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Congenital Ptosis
Levator Resection with3 Point Fixation Versus 2 Point Fixation Tucking for Congenital Ptosis
to evaluate the surgical effect of levator aponeurosis resection Versus two point fixation levator aponeurosis Tucking for Congenital Ptosis
- Trial name
- NCT03240107
- Testing
- levator resection, levator tucking
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Heba Hamdy Ibrahim Mohammed
Dermatochalasis, Ptosis, Eyelid
A Comparison of the Effect of Suture Material on Blepharoplasty Incision
The objective is to compare the effect of suture material on blepharoplasty incision. Outcomes of blepharoplasty scar and/or cosmesis will be compared between plain gut and polypropylene suture.
- Trial name
- NCT04585217
- Testing
- Randomized laterality of suture materials for closure (6-0 polypropylene monofilament suture vs fast absorbing gut suture on right eyelid)
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Congenital Ptosis
Levator Muscle Reaction for Unilateral Congenital Ptosis Repair as Compared to Levator Plication
The aim of this study was to compare the outcome of levator muscle resection with plication in mild to moderate congenital unilateral blepharoptosis.
- Trial name
- NCT05895695
- Testing
- levator muscle resection, levator muscle plication
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sohag University
Oculopharyngeal Muscular Dystrophy (OPMD)
Natural History of Oculo-Pharyngeal Muscular Dystrophy (OPMD) - Israel National OPMD Registry
The goal of this open prospective multi-disciplinary observational study of patients with OPMD at various stages of clinical manifestations is to explore the natural history of the disease in the Israeli population.
- Trial name
- Isr-OPMD (NCT07146256)
- Testing
- Non-interventional observational study
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Sheba Medical Center