Clinical trials: Ptosis
Pelvic Organ Prolapse
Comparisons of Clinical Outcomes Between Novel Tailored Transvaginal Mesh Surgery and Vaginal Native Tissue Repair Surgery for Pelvic Organ Prolapse
The issue of whether utilizing the mesh in the surgical treatment of pelvic organ prolapse remained undetermined.Thus, the aim of this study is to analyze clinical outcome of women who underwent pelvic organ prolapse surgeries…
- Trial name
- NCT02465710
- Testing
- Pelvic organ prolapse surgery without mesh, Pelvic organ prolapse surgery with mesh
- Where
- Taiwan
- Volunteers
- 350 people
- Sponsor
- National Taiwan University Hospital
Pelvic Organ Prolapse
Interactive Web-Based Tool for Pelvic Organ Prolapse: Impact on Patient Understanding and Provider Counseling
The primary aim is to assess whether an interactive patient/provider counseling process using a web-based tool (iPadTM) will improve patient satisfaction regarding understanding of her bulge symptoms.
- Trial name
- iPad (NCT01864408)
- Testing
- "Usual practice" counseling, Standard "usual practice" clinical counseling with the pelvic organ prolapse web-based tool (iPad).
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Brow Ptosis, Surgical Wound
An Analysis of Dermabond vs. Non-Absorbable Sutures in Skin Closure for Brow Ptosis Procedures
The goal of this clinical trial is to compare Dermabond with non-absorbable sutures in skin closure after brow ptosis surgery. The main questions it aims to answer are: if Dermabond provides equivalent wound healing compared to…
- Trial name
- NCT05981443
- Testing
- Dermabond, Non-Absorbable Sutures
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Cody Blanchard
Pelvic Organ Prolapse
Lateral Suspension Versus Sacral Colpopexy POP
The aim of the study will be to compare the SCP and LLS in the management of apical prolapse at 6 weeks, 6 months, 1 year and yearly up to 2 years with the null hypothesis being that no significant differences existed between the…
- Trial name
- LLS vs SCP (NCT03644628)
- Testing
- Laparoscopic repair of anterior and apical pelvic organ prolapse
- Volunteers
- 200 people
- Sponsor
- Medical University of Vienna
LUMBAR RADICULOPATHY, Lumbar Radiculopathy Due to Spinal Nerve Compression
Maitland Mobilization Effect On Gait Kinetics And Kinematics Parameters In Patients With Lumbosacral Radiculopathy
Effect Of Maitland Mobilization On Selected Gait Kinetic And Kinematic Parameters In Patients With Lumbosacral Radiculopathy
- Conditions
- LUMBAR RADICULOPATHY, Lumbar Radiculopathy Due to Spinal Nerve Compression, Lumbar Disc Prolapse With Radiculopathy, Lumbosacral Radiculopathy
- Trial name
- NCT07448311
- Testing
- MAITHLEND MOBILIZATION, transcutaneous electrical neuromuscular stimulation, stretching hamstrings
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Cairo University
Quality of Life, Pelvic Floor Distress and Impact Scores
Physical Therapy on Quality of Life and Function Following Vaginal Surgery Reconstructive Surgery
i) The primary objective of this study is to determine if physical therapy improves postoperative quality of life in participants following vaginal reconstructive surgery for pelvic organ prolapse and urinary incontinence.
- Conditions
- Quality of Life, Pelvic Floor Distress and Impact Scores, Sexual Function Scores
- Trial name
- PT and QOL (NCT01403701)
- Testing
- Physical therapy
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- TriHealth Inc.
Pelvic Organ Prolapse
Pelvic Ultrasound Pessary Study: Changes in Pelvic Anatomy After Placing a Pessary
In the past, the impact of pessaries was mostly assessed by questionnaires on Quality of Life (QoL) and sexual dysfunction. This research project primarily aims to objectify the effects of the currently available pessaries in a…
- Trial name
- PUPS (NCT04915664)
- Testing
- Pessary
- Where
- Belgium
- Volunteers
- 269 people
- Sponsor
- Universiteit Antwerpen
Pelvic Organ Prolapse
Trial Comparing Laparoscopic Vs Robotic-assisted Colposacropexy for Pelvic Organ Prolapse Repair
The aim of the study is to perspectively compare the anatomical and functional outcomes of Pelvic Organ Prolapse (POP) repair after Laparoscopic or Robotic-assisted Colposacropexy.
- Trial name
- NCT02852512
- Testing
- sacrocolpopexy
- Where
- Italy
- Volunteers
- 62 people
- Sponsor
- University Of Perugia
Rectocele
Graft-Augmented Rectocele Repair-A Randomized Surgical Trial
The purpose of this study is to determine whether adding a graft during a rectocele repair will improve the success rate of the repair.
- Trial name
- NCT00321867
- Testing
- Graft augmented posterior repair, Control
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Women and Infants Hospital of Rhode Island
Pelvic Organ Prolapse
Retroperitoneal Tunneling Versus Dissection Technique During Sacrocolpopexy
The purpose of this study is to compare operative time, patient reported outcomes, surgical complications, and surgical outcomes between the tunneling versus dissection technique during robotic assisted sacrocolpopexy (RA SCP).
- Trial name
- NCT05969067
- Testing
- Tunneling Technique during RA SCP, Dissection Technique during RA SCP
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Pelvic Organ Prolapse, Pelvic Floor Disorders
Effect of Local Estriol Treatment Before Vaginal Repair Surgery
The aim of the study is to evaluate the effects of local estriol treatment applied before vaginal repair surgery on steroid receptors, inflammatory cell response, vascular, connective and nervous tissues in the vagina, and its…
- Conditions
- Pelvic Organ Prolapse, Pelvic Floor Disorders, Menopause, Vaginal Atrophy
- Trial name
- NCT06391372
- Testing
- estriol cream
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Hatice Tukenmez Kurnaz
Pelvic Organ Prolapse
Can Pelvic Floor Muscle Training Reduce my Prolapse
Purpose The aim of this study is to examine if a structured pelvic floor muscle training combined with lifestyle advice with can improve pelvic organ prolapse (POP) symptoms more than structured lifestyle advice programme alone.
- Trial name
- NCT01612637
- Testing
- Pelvic floor muscle training and lifestyle advice, Lifestyle advice
- Where
- Denmark
- Volunteers
- 108 people
- Sponsor
- Copenhagen University Hospital at Herlev
Pelvic Organ Prolapse
Single Versus Multi-port Robotic Assisted Sacrocolpopexy for Repair of Vaginal Apex Prolapse
A prospective randomized controlled study intended to compare the efficacy of 2 methods of robotic assisted sacrocolpopexy for the repair of vaginal apex prolapse: 1. Via single-port. 2. Via multi-port.
- Trial name
- NCT03034499
- Testing
- Single-port sacrocolpopexy, Multi-port sacrocolpopexy
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Rambam Health Care Campus
Pelvic Organ Prolapse
Sacro-Spinous Ligaments Anterior Apical Anchoring
Anterior-apical compartment mesh implants for pelvic floor reconstruction are anchored here to the Sacro-Spinous ligaments and evaluated being a feasible and effective method.
- Trial name
- NCT01842464
- Testing
- Anterior Sacro-Spinous
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Catheter Related Complication, Anterior Vaginal Wall Prolapse
Comparison of 1 Versus 2 Days Post-Operative Catheterization After Anterior Colporrhaphy
Patients who undergo anterior vaginal wall plastic surgery and place the bladder catheter during surgery are selected. The purpose of the study is to evaluate the presence of statistically significant differences in bladder…
- Trial name
- NCT06429228
- Testing
- Catheter removal after surgery
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS San Raffaele
Pelvic Organ Prolapse
Nitrofurantoin Prophylaxis During Catheter-managed Acute Urinary Retention After Pelvic Reconstructive Surgery
The specific aim of this randomized double-blind placebo-controlled trial is to determine if extended release nitrofurantoin antibiotic prophylaxis decreases the incidence of symptomatic urinary tract infection (UTI) compared…
- Trial name
- NCT02727322
- Testing
- Nitrofurantoin
- Where
- 2 sites in United States
- Volunteers
- 154 people
- Sponsor
- Halina M Zyczynski, MD
Vaginal Vault Prolapse, Pelvic Organ Prolapse
Prediction of Postsurgical Symptomatic Outcomes With Preoperative Pessary Use
This is a single center, prospective trial of pessary use prior to reconstructive pelvic floor surgery for pelvic organ prolapse.
- Conditions
- Vaginal Vault Prolapse, Pelvic Organ Prolapse, Uterine Prolapse, Pelvic Floor Prolapse
- Trial name
- NCT02680145
- Testing
- Preoperative Pessary Use
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Mayo Clinic
Anesthesia, Local, Prolapse
Tap Block vs Conventional Pain Medication for Patients Undergoing Robotic Sacrocolpopexy
The purpose of this study is to assess whether the transversus abdominis plane block (Tap block) is different than the oral postoperative pain medications in controlling pain after robotic sacrocolpopexy.
- Conditions
- Anesthesia, Local, Prolapse, Prolapse; Female, Prolapse, Vaginal
- Trial name
- SACROTAP (NCT04440475)
- Testing
- TAP block
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- ProMedica Health System
Mitral Valve Regurgitation, Mitral Valve Prolapse
CE Mark Study for the Harpoon Medical Device
The purpose of this study is to evaluate the safety and performance of the Harpoon Medical device. It is anticipated, that the Harpoon Medical device will provide advantages over current surgical interventions including: 1) a…
- Conditions
- Mitral Valve Regurgitation, Mitral Valve Prolapse, Mitral Valve Insufficiency
- Trial name
- TRACER (NCT02768870)
- Testing
- Harpoon Artificial ePTFE Chords
- Where
- 4 sites in Italy, United Kingdom
- Volunteers
- 26 people
- Sponsor
- Edwards Lifesciences
Uterine Fibroids (UF), Menstrual Disorders
Hugo™ Robotic-Assisted Surgery (RAS) System in Gynecological Subjects (Embrace Gynecology)
The purpose of this research is to evaluate the safety and performance of the investigational Medtronic Hugo™ Robotic Assisted Surgery (RAS) system when used during hysterectomy procedures, including patients being treated for…
- Conditions
- Uterine Fibroids (UF), Menstrual Disorders, Adenomyosis of Uterus, Endometriosis
- Trial name
- Embrace Gyn (NCT07120945)
- Testing
- Robotic Assisted-Surgery (RAS) Hysterectomy
- Where
- 5 sites in United States
- Volunteers
- 70 people
- Sponsor
- Medtronic - MITG