Clinical trials: Puerperal Depression
Postpartum Blues, Birth Depression
The Effect of Music Played to Newborn Mothers on Postpartum Blues
The prospective and two-arm randomized controlled study was conducted on n = 82 (41 = control, 41 = music group) mothers who gave birth at term at Trakya University Health Research and Application Center Maternity Service between…
- Conditions
- Postpartum Blues, Birth Depression, Mothers
- Trial name
- NCT06252155
- Testing
- Music
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Trakya University
Postpartum Depression
Peer Administered CBT for PPD
Postpartum depression (PPD) affects up to 20% of women and has profound effects on mothers and their infants. Unfortunately, fewer than 15% of women with PPD receive evidence-based care.
- Trial name
- PL-CBT (NCT03285139)
- Testing
- Cognitive Behavioural Therapy
- Where
- Canada
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- McMaster University
Bipolar Disorder, Major Depressive Disorder
A Study of Pregnant and Postpartum Women With and Without Mood Disorders
This study is looking at genetic, biological, and environmental causes and how all three may work together to cause postpartum mood episodes.
- Conditions
- Bipolar Disorder, Major Depressive Disorder, Postpartum Depression, Postpartum Psychosis
- Trial name
- NCT03615794
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Depression, Postpartum
Evaluation of Access to Screening for Post-partum Depression Via the Postnatal Interview Within 8 Weeks of Birth in Women Who Have Gave Birth at the Troyes Hospital ( DEPRESSIONPP )
Post-partum depression is defined as a depressive disorder with onset of symptoms in the year following childbirth. Several international studies have reported a prevalence of this condition of around pathology of around 15%.
- Trial name
- DEPRESSIONPP (NCT06469476)
- Testing
- depression post partum
- Where
- France
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Troyes
Postpartum Depression, Postpartum Anxiety
Online 1-Day CBT-Based Workshops for Preventing Postpartum Depression
To conduct a randomized controlled trial (N=408) examining the impact of an online cognitive behavioural therapy (CBT)-based workshop on rates of postpartum depression (i.e., EPDS scores at 2-months postpartum) when added to…
- Trial name
- NCT05753176
- Testing
- Online 1-Day Cognitive Behavioural Therapy-Based Workshop
- Where
- Canada
- Volunteers
- 412 people, healthy volunteers welcome
- Sponsor
- McMaster University
Postpartum Depression
Study of Home-Based Exercise to Alleviate Postpartum Depression
The purpose of this study is to evaluate the effectiveness of an aerobic home-based exercise program for the treatment of postpartum depression.
- Trial name
- NCT00384943
- Testing
- Moderate-intensity Exercise
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- McGill University
Ketamine, Lactation
The Pharmacokinetics of Ketamine in the Breast Milk of Lactating Women
Quantification of Ketamine in Breast Milk at 3 hour Intervals up to 30 hours-- obtained from lactating women who receive 2 different Intramuscular injections of ketamine on two separate days at least 5 days apart.
- Trial name
- KRF-LAC (NCT04285684)
- Testing
- ketamine in lactation
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- The Ketamine Research Foundation
Perinatal Depression, Perinatal Anxiety
The DC Mother-Infant Behavioral Wellness Program
This randomized controlled study will examine the effectiveness of patient navigation with culturally adapted cognitive-behavioral interventions and peer support groups for low-income Black/of African Descent pregnant women who…
- Conditions
- Perinatal Depression, Perinatal Anxiety, Prenatal Stress
- Trial name
- NCT05345834
- Testing
- Patient Navigation, Adapted Cognitive-Behavioral Therapy
- Where
- United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Children's National Research Institute
Postpartum Depression
Parenting Skills Group for Mothers With Postpartum Depression
The goal of this longitudinal study is to study the effects of a parenting skills group (Circle of Security Parenting, aka COSP) in mothers with postpartum depression.
- Trial name
- NCT05772897
- Testing
- Circle of Security Parenting program
- Where
- United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Preterm Birth, Health Care Utilization
Testing Feasibility of Care Coordination and Motivational Interviewing for Women With a Recent Preterm Birth
This study continues an adaptation of care coordination to address the needs of women after preterm birth. This is a small single arm open trial designed to test intervention implementation and refine the intervention before…
- Conditions
- Preterm Birth, Health Care Utilization, Tobacco Use, Contraceptive Usage
- Trial name
- NCT05120843
- Testing
- Care coordination and motivational interviewing
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Postpartum Depression, Major Depressive Disorder
Neuropsychobiological Correlates of Sex-steroid Hormone Manipulation in Healthy Women: a Risk Model for Depression
The project aimed at identifying neuropsychobiological signatures of pharmacological sex-steroid hormone manipulations in healthy women as a risk model for depression.
- Conditions
- Postpartum Depression, Major Depressive Disorder, Postpartum Psychosis, Menopause
- Trial name
- GnRHa (NCT02661789)
- Testing
- Goserelin 3.6 mg implant
- Where
- Denmark
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Gitte Moos Knudsen
Depression, Postpartum Depression
Is Vitamin D Insufficiency and Deficiency Associated With Antepartum and Postpartum Depression?
Our primary aim is to evaluate whether Vitamin D deficiency causes depressive symptoms in antepartum and postpartum depression and whether early correction of Vitamin D deficiency improves these symptoms.
- Trial name
- NCT02272387
- Testing
- Vitamin D3 (Cholecalciferol)
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Perinatal Depression, PostPartum Depression
Comparing the Effectiveness of Clinicians and Paraprofessionals to Reduce Disparities in Perinatal Depression
There is considerable evidence that most perinatal women at risk for postpartum depression do not engage in mental health services, even when referred by home visiting (HV) programs, primary care physicians, obstetricians, or…
- Trial name
- NCT02979444
- Testing
- Mothers and Babies Groups
- Where
- United States
- Volunteers
- 874 people, healthy volunteers welcome
- Sponsor
- Northwestern University
PostPartum Depression
Distant Reiki Therapy on Postpartum Period Fatigue and Depression
This research was conducted to evaluate the effect of Reiki therapy applied to women in the postpartum period on the risk of fatigue and postpartum depression.
- Trial name
- NCT06364436
- Testing
- Reiki energy therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Aksaray University
Postpartum Depression, Anxiety State
The Effect of Tele-Health Education Provided in the Postpartum Period in the Covid 19 Pandemic
In the planned study, it was aimed to examine the effect of tele-education offered in the postpartum period in the covid 19 pandemic on the levels of depression, attachment and anxiety of women.
- Trial name
- NCT04847362
- Testing
- Experimental
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Postpartum, Fatigue
Postnatal Companion Support The Effect of Education on Maternal Depression and Fatigue
In this study, it is aimed to investigate the effect of the trainings included in the content of the practical guide for postpartum supporter training companions, which will be given to the companions of women in the postpartum…
- Conditions
- Postpartum, Fatigue, Depression, Social Support
- Trial name
- NCT06505733
- Testing
- postnatal attendant training
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Microbial Colonization
Comparing Impacts of Donor Human Milk to Formula Supplementation on the Gut Microbiome of Full-term Infants
The goal of this pilot randomized controlled trial (RCT) is to examine donor human milk (DHM) as a clinical intervention targeted at achieving beneficial microbiome signatures in full-term infants who are exposed to intrapartum…
- Trial name
- PPDHM (NCT05815433)
- Testing
- Donor Human Milk - Nutritional Replacement
- Where
- Canada
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Anesthesia, Analgesia
The Efficacy and Safety of S-ketamine in Elective Cesarean Section
During the past years, a large number of clinical trials have investigated the use of the non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist racemic ketamine as an adjunct to local anaesthetics, opioids, or other…
- Conditions
- Anesthesia, Analgesia, Depression, Cesarean Section
- Trial name
- ES-CS (NCT04657107)
- Testing
- S-ketamine, normal saline
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- Beijing Obstetrics and Gynecology Hospital
Depression
Sertraline for the Prevention of Recurrent Postpartum Depression
This study will determine the effectiveness of taking sertraline within 24 hours of giving birth in preventing a recurrence of postpartum depression.
- Trial name
- NCT00276900
- Testing
- Sertraline
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Pregnancy Related, Burnout, Professional
The 4th Trimester Initiative: The Impact of Parental Support on Pregnant Trainee Wellbeing
The goal of this clinical trial is to determine the impact of a parental support package for new trainee mothers which focuses on mentorship, lactation, and sleep, and access to perinatal care.
- Conditions
- Pregnancy Related, Burnout, Professional, Wellness, Psychological
- Trial name
- NCT06014892
- Testing
- Snoo smart bassinet, Willow wearable breast pump, Maven Clinic on-demand perinatal consultation
- Where
- 7 sites in United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital