Clinical trials: Puerperal Disorder
Postpartum Hemorrhage, Twin
Carbetocin at Elective Cesarean Deliveries: A Dose-finding Study in Women With Twin Pregnancy.
Poor uterine tone after the birth of a baby can cause excess bleeding (called postpartum hemorrhage or PPH). This is a major cause of maternal death worldwide.
- Trial name
- NCT04182360
- Testing
- Carbetocin
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Hemophilia A, Hemophilia A, Severe
Hemophilia A Research Program
This study longitudinally observes the intergenerational (mother-child) continuum in hemophilia A from pregnancy through early childhood.
- Conditions
- Hemophilia A, Hemophilia A, Severe, Factor VIII (FVIII), FVIII Deficiency
- Trial name
- HARP (NCT07414511)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Washington
Depression, Anxiety, Antenatal Depression
Integration of Stepped Care for Perinatal Mood and Anxiety Disorders Among Women Attending MCH Clinics
Perinatal mood and anxiety disorders (PMAD), defined as depression and anxiety during pregnancy or up to 1 year postpartum, account for substantial morbidity and mortality among birthing people globally especially in low- and…
- Conditions
- Depression, Anxiety, Antenatal Depression, Postnatal Depression
- Trial name
- IPMH (NCT06456307)
- Testing
- Integrated Perinatal Mental health program (systematic screening for PMAD, PM+ and tele-psychiatry)
- Where
- 2 sites in Kenya
- Volunteers
- 2,970 people, healthy volunteers welcome
- Sponsor
- Kenyatta National Hospital
Postpartum Depression
A Descriptive Study of the Correlation Between Postpartum Depression and Body Image Dissatisfaction, Self-objectification, and Social Media Appearance Comparison
The goal of this observational study is to assess the prevalence of postpartum depression and analyze its relationship with body image dissatisfaction, self-objectification, and social media appearance comparison in postpartum…
- Trial name
- NCT07603063
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Postpartum Depression, Maternal-Fetal Relations
Effect of Listening to Surah Al-Inshirah (The Opening-Up of the Heart) After Cesarean Birth on Postpartum Outcomes
This randomized controlled trial aims to evaluate the effect of listening to the recitation of Surah Al-Inshirah during the early postpartum period after cesarean birth on women's spiritual well-being, depression levels, and…
- Conditions
- Postpartum Depression, Maternal-Fetal Relations, Spirituality
- Trial name
- NCT07354334
- Testing
- Listening to Surah Al-Inshirah
- Where
- Turkey (Türkiye)
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Mother-Infant Interaction, Postnatal Depression
Effects of Type of Delivery Mode and Gestational Age on Maternal Bonding
To evaluate the effects of gestational age and other factors on maternal attachment relationship. There are different results in studies examining the effects of birth type on postpartum depression and mother-infant interaction.
- Conditions
- Mother-Infant Interaction, Postnatal Depression, Postpartum Anxiety
- Trial name
- NCT04396509
- Testing
- Maternal Attachment Inventory Score
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
PostPartum Depression
Distant Reiki Therapy on Postpartum Period Fatigue and Depression
This research was conducted to evaluate the effect of Reiki therapy applied to women in the postpartum period on the risk of fatigue and postpartum depression.
- Trial name
- NCT06364436
- Testing
- Reiki energy therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Aksaray University
Tobacco Use Disorder
Progesterone for Smoking Relapse Prevention Following Delivery
Smoking is the main preventable cause of mortality in Western countries, contributing to over 430,000 deaths a year in the U.S. alone.
- Trial name
- NCT01972464
- Testing
- Progesterone
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Yale University
Postpartum Depression, Lifestyle, Healthy
Nutrition and Physical Activity Intervention on Psychosocial Well-Being of Postpartum Mothers
This study aims to examine the effectiveness of nutrition and physical intervention to improve psychosocial well-being of postpartum mothers with preterm infants.
- Trial name
- NCT05444179
- Testing
- Mommies can Eat & Exercise with No Stress (MomEENS)
- Where
- Malaysia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universiti Teknologi Mara
Postpartum Hemorrhage
Carbetocin at Elective Cesarean Delivery Part 4
PostPartum hemorrhage (PPH) is a major cause of maternal death worldwide. Oxytocin is the most commonly used uterotonic drug to prevent and treat PPH in North America.
- Trial name
- NCT02264769
- Testing
- Carbetocin
- Where
- Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Obesity
Fit Moms in Partners, Children, and Other Members
The purpose of this ancillary study is to determine whether a behavioral weight loss intervention for postpartum mothers (5R01DK087889-02, PI Phelan; Co-I Tate) has a positive "ripple" effect on weight and health of partners and…
- Trial name
- NCT01921959
- Testing
- Intervention
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- California Polytechnic State University-San Luis Obispo
Prolonged Labor, Healthy
Epidural Analgesia on Electrophysiological Function
Combined spinal-epidural analgesia (CSEA) is sometimes used for difficult births, but whether it contributes to postpartum pelvic muscle disorder is unclear.
- Conditions
- Prolonged Labor, Healthy, Pelvic Floor Disorders
- Trial name
- NCT02334150
- Testing
- CSEA (ropivocaine and sufentanil)
- Where
- China
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- Nanjing Maternity and Child Health Care Hospital
Postpartum Depression
Remote Peer Support in Prevention of Postpartum Depression
The project aims to test the clinical effectiveness of the Mom´s Supporting Moms intervention, a newly developed approach to the prevention of postpartum depression (PPD) and to determine its cost-effectiveness.
- Trial name
- NCT04639752
- Testing
- Mom´s Supporting Mom, Enhanced Treatment As Usual
- Where
- Czechia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health, Czech Republic
Postpartum Hemorrhage
Emergency Peripartum Hysterectomy: A Prospective Study in Iran
The purpose of this study is to determine the effects of peripartum hysterectomy for maternal hemorrhage.
- Trial name
- NCT01285258
- Testing
- hysterectomy
- Where
- Iran
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Anemia
Iron Supplementation Among Low-Income Postpartum Women
Anemia is common among low-income women after they have given birth. Anemia, or low hemoglobin in the blood cells, is usually caused by not having enough iron. Blood cells usually carry oxygen to other parts of the body.
- Trial name
- NCT00207610
- Testing
- Daily iron supplements of 65 mg a day for 3 months, Universal anemia screening and treatment, Selective anemia screening and treatment
- Where
- United States
- Volunteers
- 959 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Hypertension
Monitoring and Testing of Blood Pressure in Postpartum Women
The purpose of this research study is to find out the usefulness of checking a woman's blood pressure remotely (at home) for 3 weeks after being discharged from the hospital after having a baby (or babies).
- Trial name
- SMART-BP (NCT05236725)
- Testing
- Remote Blood Pressure Cuff, Blood pressure monitoring smart phone app, BabyScripts™, Instructions
- Where
- United States
- Volunteers
- 1,607 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Psychological Distress, Pregnancy Related
Mindful Moms: Mechanisms of Mindfulness-based Cognitive Therapy During Pregnancy and Postpartum
The proposed study seeks to elucidate the mechanisms underlying Mindfulness-Based Cognitive Therapy in pregnancy to improve understanding of how and why this treatment modality enhances well-being, which can then be leveraged to…
- Conditions
- Psychological Distress, Pregnancy Related, Postpartum Blues, Postpartum Depression
- Trial name
- NCT05137925
- Testing
- Mindfulness-Based Cognitive Therapy (MBCT), Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Depression, Pregnancy
Effects of Maternal Depressive Symptomatology on Pregnancy Outcomes and Newborn Development --- How is Paternal Psychopathology Involved?
This study aims at investigating the effects of maternal depressive symptomatology on pregnancy outcomes and newborn development. How paternal psychopathology is involved in the association will also be explored.
- Trial name
- NCT01280474
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University WanFang Hospital
Perineal Trauma, Pelvic Floor Dysfunction
Pelvic Floor Training Program and Perineal Trauma During Vaginal Birth
This study aims to determine whether a structured pelvic floor muscle training program during pregnancy can reduce perineal trauma during vaginal birth.
- Conditions
- Perineal Trauma, Pelvic Floor Dysfunction, Labor Complications, Pelvic Floor Muscle Training
- Trial name
- PFTP (NCT07292948)
- Testing
- Pelvic Floor Muscle Training Program
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Mehmet Incebıyik
Postpartum Depression
Interpersonal Therapy-Based Treatment to Prevent Postpartum Depression in Adolescent Mothers
The Specific Aim of this study is to conduct a randomized controlled trial to evaluate whether Project REACH (an interpersonal psychotherapy-based intervention) compared with a didactic attention-control program reduces the risk…
- Trial name
- REACH 2 (NCT01482832)
- Testing
- Interpersonal therapy-based treatment
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island