Clinical trials: Puerperal Disorder
Oxytocin Deficiency, Postpartum Depression
The Relationship Between Oxytocin Level and Postpartum Depression
There are studies in the literature that associate oxytocin level with postpartum depression. This study was carried out to investigate the relationship between oxytocin levels measured during pregnancy and postpartum depression…
- Conditions
- Oxytocin Deficiency, Postpartum Depression, Prenatal Stress
- Trial name
- NCT04427410
- Testing
- Salivary test
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Postpartum Hemorrhage
Postpartum Hemorrhage After Shenghua Decoction Treatment
A rare case of disastrous delayed postpartum hemorrhage after three days of shenghua decoction treatment.
- Trial name
- NCT04027920
- Testing
- Shenghua Decoction
- Where
- Taiwan
- Volunteers
- 1 people
- Sponsor
- Far Eastern Memorial Hospital
Pregnancy, High Risk, Child Development
Nurse Family Partnership for Women With Previous Live Births
The goal of this clinical trial is to test the Nurse Family Partnership (NFP) in mothers with previous live births (multiparous or multip individuals).
- Conditions
- Pregnancy, High Risk, Child Development, Post Partum Depression
- Trial name
- NCT05887115
- Testing
- Nurse Family Partnership
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Postpartum Depression, Covid19
Screening for Postpartum Depression and Associated Risk Factors Among Women Who Deliver in Four Hospital in France During the COVID-19 Epidemic
Postpartum depression (PPD) represent around 15% of birth in developed countries. The context of the COVID-19 epidemy represents a possible source of additional emotional distress.
- Conditions
- Postpartum Depression, Covid19, Prevalence, Social Distance
- Trial name
- COVIE-19/20 (NCT04487171)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 38 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Postpartum Depression, Postpartum Anxiety
A Pilot Trial of the Reach Out, Stay Strong, Essentials for Mothers of Newborns (ROSE) Postpartum Depression Prevention Intervention in Pregnant Patients Admitted to Strong Hospital
This study is a pilot, single-center, randomized controlled trial. It will 1. determine feasibility and acceptability of an evidence-based intervention for prevention of postpartum depression with antepartum patients on a…
- Trial name
- NCT05225025
- Testing
- ROSE, Standard of Care
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Rochester
HIV Infections
Pharmacokinetic Study of Antiretroviral Drugs and Related Drugs During and After Pregnancy
IMPAACT P1026s is a Phase IV prospective clinical study to evaluate the pharmacokinetics (PKs) of antiretroviral (ARV) and tuberculosis (TB) medications in pregnant women and their infants.
- Trial name
- NCT00042289
- Testing
- atazanavir/cobicistat, darunavir/ritonavir dosage #1, darunavir/ritonavir dosage #2
- Where
- 62 sites in United States, Argentina and 6 more
- Volunteers
- 1,578 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Cardiovascular Disease, Preeclampsia
Heart Health 4 Moms Trial to Reduce CVD Risk After Preeclampsia
This study will compare two arms in a randomized clinical trial of cardiovascular risk prevention in women with a history of preeclampsia.
- Conditions
- Cardiovascular Disease, Preeclampsia, Hypertension, Post-partum Weight Retention
- Trial name
- HH4M (NCT02147626)
- Testing
- Web-based educational and motivational modules, Information and Screening Group
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Urinary Retention, Urinary Tract Infection (Diagnosis)
How the Method of Bladder Emptying After Epidural Placement in Labor Affects Postpartum Voiding
At least ten percent of patients have postpartum urinary retention or difficulty urinating after birth, which can cause incontinence and other urinary problems long-term.
- Conditions
- Urinary Retention, Urinary Tract Infection (Diagnosis), Postpartum Acute Urinary Retention, Postpartum Care
- Trial name
- NCT07125326
- Testing
- Intermittent catheterization, Continuous catheterization
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Pittsburgh
Postpartum Sepsis, Postpartum Endometritis
Antibiotic Prophlaxis for High-risk Laboring Women in Low Income Countries
This study, performed over a course of 3 years in 5 collaborating hospitals in Cameroon, Africa, will randomize 750 women in labor with prolonged rupture of membranes ≥ 8 hours or prolonged labor ≥ 18 hours to identical oral…
- Conditions
- Postpartum Sepsis, Postpartum Endometritis, Postpartum Fever
- Trial name
- NCT03248297
- Testing
- Azithromycin, Azithromycin and amoxicillin
- Where
- Cameroon
- Volunteers
- 756 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Digital Intervention, Bibliotherapy
Digital Support Intervention for Pregnant People with Opioid Use Disorders
The goal of this pilot randomized feasibility study is to explore the benefits of providing parenting and recovery support for pregnant people with Opioid Use Disorders through digital technology (e.g. smartphones).
- Trial name
- PARENTSS (NCT06652880)
- Testing
- Digital technology, Bibliotherapy
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of South Carolina
Postpartum Depression
A Prospective Study of Postpartum Depression in Women With Major Depression
Background: Postpartum depression (PPD) is a serious syndrome that resembles a major depressive episode and occurs in 10% to 20% of all mothers in the year following delivery.
- Trial name
- NCT01328613
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- National Institute on Aging (NIA)
Obstetric Anesthesia Problems, Placenta Accreta
Fibrinogen Concentrate and Placenta Acreta Spectrum
The aim of this study is to evaluate the relationship between fibrinogen use and bleeding in patients who underwent cesarean section with a prediagnosis of PAS.
- Trial name
- NCT05938062
- Testing
- the group without fibrinogen concentrate (GNF) , the group with fibrinogen concentrate (GF)
- Where
- Turkey (Türkiye)
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Anorexia Nervosa, Eating Disorders
Perceptions of Their Own Body and of the Body of Their Child Among Young Mothers With Anorexia Nervosa
The BodyBabe studies aims to evaluate the perceptions that young mothers with anorexia nervosa (active or in remission) have of their own body and of the body of their child.
- Trial name
- BodyBabe (NCT04233450)
- Testing
- BodyBabe questionnaire
- Where
- France
- Volunteers
- 12 people
- Sponsor
- University Hospital, Clermont-Ferrand
Severe Preeclampsia
Effectiveness Study of Short Course of Magnesium Sulfate for Severe Preeclamsia
Magnesium sulfate is the ideal drug for seizures prophilaxis in preeclampsia. The ideal duration of this treatment after delivery is still to be established.
- Trial name
- MgSO4 (NCT01408979)
- Testing
- Magnesium sulfate 12 hours, Magnesium sulfate 24 hours
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Hypertension in Pregnancy, Preeclampsia
Response to Anti-hypertensives in Pregnant and Postpartum Patients
In this study, the investigators will evaluate the blood pressure response to nifedipine and labetalol in pregnant and postpartum patients, who present with hypertensive disease in pregnancy with severe range blood pressure…
- Trial name
- NCT03506724
- Testing
- Nifedipine, Labetalol
- Where
- 2 sites in United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Postpartum Depression
The Effect of Peripartum Magnesium Sulfate Use on the Occurrence of Postpartum Depression
This is an observational study that will be conducted on pregnant women under vaginal delivery or cesarean section. The magnesium sulfate will be given to appropriate participants with a protocol that obstetrician are already…
- Trial name
- NCT05751746
- Testing
- Magnesium sulfate
- Where
- South Korea
- Volunteers
- 108 people
- Sponsor
- Seoul National University Bundang Hospital
Postpartum Hemorrhage, Maternal Death
Novel Vacuum-Induced Hemorrhage Control for Postpartum Hemorrhage
This will be the first, definitive, randomized control trial (N=424) to test the hypothesis that the Jada® System is effective, safe and cost-effective in treating PPH, compared to standard care.
- Trial name
- NOVIC (NCT05382403)
- Testing
- Jada® System, Standard care
- Where
- 2 sites in Ghana
- Volunteers
- 424 people
- Sponsor
- Women and Infants Hospital of Rhode Island
Postpartum Depression (PPD), Alcohol Use
Maternal Outcomes: Mood, Alcohol Use, and Depressive Symptoms
This study aims to learn about depression and alcohol use in postpartum mothers and whether an intervention based on contingency management and problem-solving therapy (CM-PST) can help reduce these symptoms.
- Conditions
- Postpartum Depression (PPD), Alcohol Use, Contingency Management, Problem Solving Therapy
- Trial name
- MOMS-AD (NCT07485036)
- Testing
- Contingency Management & Problem Solving Therapy, Usual Care
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Illinois Chicago
Depression, Postpartum
Effectiveness of Sertraline Alone and Interpersonal Psychotherapy Alone in Treating Women With Postpartum Depression
This study will evaluate the effectiveness of antidepressant medication alone and interpersonal psychotherapy alone in treating women with postpartum depression.
- Trial name
- NCT00602355
- Testing
- Sertraline, Interpersonal psychotherapy (IPT), Clinical management
- Where
- 2 sites in United States
- Volunteers
- 162 people
- Sponsor
- Women and Infants Hospital of Rhode Island
Postpartum Depression
Prenatal Yoga to Prevent Postpartum Depression
Although psychological interventions exist for the prevention of PPD, a yoga-based intervention to prevent PPD among at-risk women utilizes a similar theoretical foundation (i.e., mindfulness), may be more acceptable to women of…
- Trial name
- PRY-D (NCT06004232)
- Testing
- Prenatal Yoga to Prevent Postpartum Depression (PRY-D) intervention, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Henry Ford Health System