Clinical trials: Puerperal Disorders
Parturition, Analgesia, Obstetrical
Neuraxial Labor Analgesia and the Incidence of Postpartum Depression
Postpartum depression (PPD) affects approximately 15% of women during the first year after giving birth, and is common across cultures. The etiology of postpartum depression is not totally clear.
- Conditions
- Parturition, Analgesia, Obstetrical, Depression, Postpartum
- Trial name
- NCT02823418
- Testing
- No neuraxial labor analgesia, Neuraxial labor analgesia
- Volunteers
- 599 people
- Sponsor
- Peking University First Hospital
Postpartum Depression, Postpartum Blues
Proactive, Personalized Postpartum Mental Healthcare
Mental health symptoms - especially depression and anxiety - are very common in new parents, affecting close to 20% of mothers and at least 10% of fathers.
- Conditions
- Postpartum Depression, Postpartum Blues, Postpartum Anxiety, Postpartum Mood Disorder
- Trial name
- P3MH (NCT03803189)
- Testing
- Usual care plus eToolkit
- Where
- 2 sites in Canada
- Volunteers
- 130 people
- Sponsor
- Women's College Hospital
Midwifery Student
The Effect of Gamification-Based Instructional Design Developed
Turkish) Abstract: Purpose: Considering the importance of postpartum hemorrhage management in reducing preventable maternal deaths and the key role midwives play in providing this care, it is important to increase the knowledge…
- Trial name
- PPH-GamEd (NCT07207590)
- Testing
- web-based gamification application, control group: traditional classroom learning techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Severe Postpartum Depression
A Study to Evaluate SAGE-547 in Participants With Severe Postpartum Depression
This is a multicenter, randomized, double-blind, parallel-group, placebo-controlled study of the efficacy, safety, and pharmacokinetics of SAGE-547 Injection in adult female participants diagnosed with severe postpartum…
- Trial name
- NCT02614547
- Testing
- SAGE-547
- Where
- 4 sites in United States
- Volunteers
- 21 people
- Sponsor
- Supernus Pharmaceuticals, Inc.
Placenta Accreta, Post Partum Hemorrhage
Tourniquet Reduces Blood Loss in Postpartum Hemorrhage During Hysterectomy for Placenta Accreta
Monocentric prospective observational study comparing the use of tourniquet in low uterus segement versus standard procedure in hysterectomy owing to placenta accreta
- Conditions
- Placenta Accreta, Post Partum Hemorrhage, Blood Loss Massive
- Trial name
- NCT03707132
- Testing
- Tourniquet: Folley catheter in the low segment of the uterus
- Volunteers
- 43 people
- Sponsor
- University Tunis El Manar
Premature Birth
Exploring the Feasibility of Centering Pregnancy With Care Navigation
Pacific Islanders residing in the United States (US) have disproportionally high rates of preterm birth (<37 weeks) and low birthweight infants (<2,500 grams).
- Trial name
- NCT05645549
- Testing
- Centering Pregnancy with Care Navigation
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Preterm Birth
Labor Characteristics and Maternal-Infant Outcomes in Preterm Primiparous Women
This retrospective observational study evaluates labor characteristics in primiparous women with spontaneous preterm birth at different gestational ages and examines their associations with maternal and neonatal outcomes.
- Trial name
- NCT07844499
- Testing
- Gestational Age at Delivery
- Where
- China
- Volunteers
- 436 people
- Sponsor
- Maternal and Child Health Hospital, Jiading District
Family Planning Services, Post Partum Depression
Mental and Reproductive Health Integration and Access
The goal of this clinical trial is to learn whether an integrated package of mental health screening, brief psychosocial support, and family planning counseling delivered within routine postnatal care can improve reproductive and…
- Trial name
- MARIA (NCT07659509)
- Testing
- MARIA Integrated Maternal Mental Health and Family Planning Package
- Where
- 2 sites in Jordan
- Volunteers
- 920 people
- Sponsor
- Eastern Mediterranean Public Health Network
Mental Disorders of Mother, Postpartum
Mindfulness for African Americans Postpartum
A randomized clinical trial (RCT) design will be used to compare an 8-week Mindfulness for African Americans Postpartum (MAAP) intervention to an 8-week Educational Program (active comparison group).
- Trial name
- MAAP (NCT05280938)
- Testing
- MAAP, Educational Program
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Loyola University
Preeclampsia, Preeclampsia Severe
Nudge to Drive Transitions of Care
Hypertensive disorders of pregnancy (HDP) are stress tests which may identify women at high risk of future cardiovascular disease (CVD), the leading cause of death among women.
- Conditions
- Preeclampsia, Preeclampsia Severe, Gestational Hypertension, Hypertensive Disorder of Pregnancy
- Trial name
- REMIND (NCT04660032)
- Testing
- Nudge
- Where
- United States
- Volunteers
- 224 people
- Sponsor
- University of Pennsylvania
Depression, Postpartum, Anxiety
Preventing Postpartum Depression With Intranasal Oxytocin
The purpose of this study is to test a new treatment for preventing childbirth-related mental illness in postpartum mothers. The treatment is aimed at enhancing maternal bonding, reducing postpartum depression (PPD) and anxiety…
- Trial name
- IN-OXT (NCT02505984)
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Massachusetts General Hospital
Bowel Dysfunction
Gastrointestinal Activation Post-elective CS (Cesarean Section) :A Comparison of Paula Method to Standard Care
Women generally report discomfort and a delay in GI motility after CS. The Paula method, circular exercises of ring muscles has been shown to increase GI motility. This method had not been studied in women post CS.
- Trial name
- NCT03761147
- Testing
- Paula exercises
- Where
- Israel
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Pregnant Women With Singleton Pregnancies
Harvesting Health: Advancing Nutrition and Wellness for Moms and Babies
This is a randomized controlled trial to assess whether a personalized food kit to pregnant women is feasible, improves diet quality, and enhances pregnancy and birth outcomes compared to standard prenatal care.
- Trial name
- HH (NCT07659821)
- Testing
- Food Kit
- Where
- 3 sites in United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Pregnancy Related, Vitamin B 12 Deficiency
Vitamin B12 Supplementation During Pregnancy on Cognitive Development
Scientific basis: Globally, vitamin B12 deficiency is one of the most common micronutrient deficiencies. The only relevant source of vitamin B12 is animal-source foods and poor gut function may decrease absorption.
- Conditions
- Pregnancy Related, Vitamin B 12 Deficiency, Anemia
- Trial name
- VitaPreg (NCT03071666)
- Testing
- cobalamin
- Where
- Nepal
- Volunteers
- 800 people
- Sponsor
- Centre For International Health
Placenta Previa
Mostafa Maged Technique to Control and Prevent the Post-Partum Bleeding From the Lower Uterine Segment in Placenta Previa Cases
Post - partum haemorrhage is still a headache to all obstetricians around the whole world . Every obstetrician exerts his own full effort to control bleeding which can occur post-partum by applying all maneuvers to preserve the…
- Trial name
- NCT05283122
- Testing
- Mostafa Maged Technique
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Fayoum University
Viral Hepatitis B, Contraception
Blood-borne Infection Screening in an Afghan Antenatal Population
Baseline information indicates there are measurable levels of hepatitis B SAg and low utilization of postpartum contraception, correct breastfeeding practices, or adherence to infant vaccination schedules in Kabul, Afghanistan.
- Conditions
- Viral Hepatitis B, Contraception, Breast Feeding, Exclusive, Effects of; Lack of Care of Infants
- Trial name
- NCT01199601
- Testing
- Concentrated postpartum counseling
- Where
- Afghanistan
- Volunteers
- 1,291 people, healthy volunteers welcome
- Sponsor
- Columbia University
Cystic Fibrosis
CFTR Modulators in Pregnancy and Postpartum
Observational study on women with Cystic Fibrosis treated with CFTR modulators during pregnancy and postpartum and their children.
- Trial name
- NCT06302270
- Where
- Sweden
- Volunteers
- 75 people
- Sponsor
- Region Stockholm
Obesity, Pregnancy
Bringing NELIP for Obese Pregnant Women Into Clinical Practice
This is a pilot project in which investigators will recruit obese (pre-pregnancy BMI of ≥ 35 kg/m2) women from the newly developed "My Clinic" at London Health Sciences Centre as well as normal obstetrical care at London Health…
- Trial name
- NCT02155751
- Testing
- Nutrition Lifestyle Intervention Program (NLIP), Exercise Lifestyle Intervention Program (ELIP)
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Cardiovascular Diseases, Diabetes
Fit After Baby: Increasing Postpartum Weight Loss in Women at Increased Risk for Cardiometabolic Disease
This study plans to learn more about how to increase postpartum weight loss and how to decrease risk factors for postpartum women at increased risk for diabetes and heart disease.
- Conditions
- Cardiovascular Diseases, Diabetes, Gestational Diabetes, Preeclampsia
- Trial name
- FAB (NCT03215173)
- Testing
- Fit After Baby, Text4Baby Control Group
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Perinatal Depression, Ketamine
Low-dose Ketamine and Postpartum Depression in Parturients With Prenatal Depression
Postpartum depression is common in mothers early after childbirth and produces harmful effects not only on mothers, but also on infants and young children.
- Conditions
- Perinatal Depression, Ketamine, Cesarean Delivery, Postpartum Depression
- Trial name
- NCT03336541
- Testing
- Ketamine
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Peking University First Hospital