Clinical trials: Pulmonary Air Leaks
Pulmonary Air Leaks
Spiration Valves Against Standard Therapy
VAST is a multicenter, prospective, randomized, controlled study designed to evaluate treatment of persistent air leak with the SVS as compared to standard chest tube drainage management and other standard-of-care interventions…
- Trial name
- VAST (NCT02382614)
- Testing
- Spiration Valve System
- Where
- 20 sites in United States
- Volunteers
- 75 people
- Sponsor
- Olympus Corporation of the Americas
Air Leak From Lung, Pneumothorax
Feasibility and Accuracy of a Novel Pleural Drain Gas Analyzer in Detecting Air Leaks
The goal of this study is to assess the clinical feasibility of a novel, reusable, low cost gas analyzer that detects breath in chest drains in order to diagnose and heal air leaks.
- Trial name
- NCT06548386
- Testing
- Pleural gas analysis
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Lung Healing Technologies Inc
Air Leak From Lung
Hemopatch Compared to TachoSil in Postoperative Air Leak Duration After Pulmonary Resection
This study is a randomized, controlled study, with the primary objective to demonstrate non-inferiority of Hemopatch compared to TachoSil in postoperative air leak duration after pulmonary resection, and with the secondary…
- Trial name
- NCT03450265
- Testing
- Hemopatch, Tachosil
- Where
- 14 sites in Italy, Spain
- Volunteers
- 279 people
- Sponsor
- Baxter Healthcare Corporation
Lung Disease, Pulmonary Lobectomy
PleuraSeal Post Market Study (Europe)
To further characterize the PleuraSeal Sealant System as compared to standard of care (sutures and staples only) in subjects undergoing an elective pulmonary lobectomy and segmentectomy via open thoractomy.
- Trial name
- NCT00704171
- Testing
- Standard Tissue Closure Techniques, PleuraSeal Lung Sealant System
- Where
- 9 sites in United States, Austria and 4 more
- Volunteers
- 121 people
- Sponsor
- Integra LifeSciences Corporation
Open Thoracotomy
PleuraSeal Pivotal Study (US)
To evaluate the safety and effectiveness of Confluent Surgical's PleuraSeal Sealant System in the treatment and control of intra and postoperative air leaks following pulmonary resection via an open thoracotomy.
- Trial name
- NCT00748124
- Testing
- PleuraSeal Sealant System, Standard Tissue Closure Techniques
- Where
- United States
- Volunteers
- 230 people
- Sponsor
- Integra LifeSciences Corporation
Post-operative Air Leaks
Observational Study of TissuePatch SF in Prevention of Air Leaks Following Lung Resection
Post-market, observational study to assess effectiveness of TissuePatch SF in managing/preventing air leaks after lung resection.
- Trial name
- NCT06934486
- Testing
- TissuePatch Sealant Film
- Volunteers
- 250 people
- Sponsor
- C. R. Bard
Lung Cancer, Lung Tumor
NeoMend ProGEL™ Pleural Air Leak Sealant Post-Approval Study
The purpose of this post approval study is to further characterize the safety profile of the ProGEL™ Pleural Air Leak Sealant in commercial use, with specific reference to long-term safety over 90 days of follow-up.
- Trial name
- NCT01394978
- Testing
- Control, ProGEL Pleural Air Leak Sealant with standard surgical closure, ProGEL Pleural Air Leak Sealant without standard surgical closure
- Where
- 18 sites in United States
- Volunteers
- 444 people
- Sponsor
- C. R. Bard
Postoperative Air Leaks in Risk Patients
Clinical Trial Phase I/II Prospective, Open Nonrandomized for Treatmen of Postoperative Air Leak After Lung Resection in High Risk Patients Through the Administration of Mesenchymal Autologous Cells
The purpose of this study is to analyze the safety and feasibility of the implantation of autologous mesenchymal stem cells (MSCs) expanded "in vitro" and administered directly in the lung line of suture as a treatment for…
- Trial name
- CSM/FAP/2012 (NCT02045745)
- Testing
- Implantation of autologous mesenchymal stem cells (CSM) expanded "in vitro" and administered directly into the lung suture line
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Red de Terapia Celular