Clinical trials: Pulmonary Atelectases
Pulmonary Atelectasis
Lung Ultrasound and Alveolar Recruitment in Mechanically Ventilated Infants
Investigators hypothesized that lung ultrasound-assisted recruitment maneuver would be beneficial in mechanically ventilated infants compared to those who did not receive lung ultrasound and alveolar recruitment maneuver.
- Trial name
- NCT02584023
- Testing
- Lung ultrasound
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Respiratory Distress, Newborn
Effectiveness of HVNI in Preterm Infants With Moderate Respiratory Distress
Neonatal respiratory distress is a common problem in preterm infants. The application of CPAP is widely used in neonatal units as a primary mode of respiratory support for respiratory distress.
- Trial name
- NCT06436222
- Testing
- HVNI
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Postoperative Pulmonary Atelectasis, Surgery
Prophylactic nCPAP Following Bowel Surgery (Bio-REB File 11-27)
The purpose of this study is to determine whether prophylactic nasal continuous positive airway pressure (nCPAP) in the post-anaesthesia care unit (PACU) improves post-operative pulmonary function following elective bowel…
- Trial name
- NCT01316575
- Testing
- nCPAP, Low Flow Oxygen
- Volunteers
- 40 people
- Sponsor
- University of Saskatchewan
Right Ventricular Function, Prone Position
Bedside Assessment of Right Ventricular Output Lying in Prone Or Supine
Right ventricular failure (RVF) is a common complication to cardiac surgery, which is associated to mortality, kidney failure, stroke, prolonged mechanical ventilation and ICU stay.
- Conditions
- Right Ventricular Function, Prone Position, Atelectasis, Atelectases, Postoperative Pulmonary
- Trial name
- BAROLO (NCT07632027)
- Testing
- Prone position
- Where
- Sweden
- Volunteers
- 70 people
- Sponsor
- Sahlgrenska University Hospital
Respiratory Insufficiency, Pneumonia
Evaluation of a Disposable Flexible Bronchoscope, aScope IV
Flexible bronchoscopes are typically reusable and therefore need high level disinfection to prevent inadvertent spread of microbial pathogens from patient to patient. The process of disinfection is time consuming and expensive.
- Conditions
- Respiratory Insufficiency, Pneumonia, Atelectasis
- Trial name
- EVAL (NCT02255838)
- Testing
- Bronchoscope reusable (Storz 8402 2x), Bronchoscope disposable (aScope 4)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Louisville
Atelectases, Postoperative Pulmonary, Diabete Mellitus
The Role Intraoperative Salbutamol Inhaler in Preventing Atelectasis
Atelectasis is considered a common complication in the perioperative period, especially following surgeries under general anesthesia.
- Trial name
- NCT07591558
- Testing
- Salbutamol (Ventolin®)
- Where
- Jordan
- Volunteers
- 80 people
- Sponsor
- King Abdullah University Hospital
Newborn Respiratory Distress Syndrome
HHHFNC (Heated Humidified High-Flow Nasal Cannula) Versus NCPAP for Respiratory Distress Syndrome of Prematurity
Preterm infants ranging from 29+0 to 36+6 weeks+days are randomly assigned to one of the following treatments as non invasive respiratory support if they develop mild to moderate Respiratory Distress Syndrome within 72 hrs from…
- Trial name
- NCT02570217
- Testing
- HHHFNC, NCPAP
- Where
- Italy
- Volunteers
- 316 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Postoperative Complications, Atelectasis
High-Flow Nasal Cannula After Major Abdominal Surgery to Prevent Postoperative Pulmonary Complications
Major abdominal surgery is associated with a substantial risk of early postoperative pulmonary complications, including atelectasis, hypoxemia, pneumonia, and increased need for respiratory support.
- Conditions
- Postoperative Complications, Atelectasis, Pneumonia, Respiratory Insufficiency
- Trial name
- NCT07528404
- Testing
- High flow nasal cannula (HFNC), Standard oxygen therapy
- Where
- South Korea
- Volunteers
- 580 people
- Sponsor
- Uijeongbu St. Mary Hospital
Bariatric Surgery Candidate, Atelectasis, Postoperative Pulmonary
Ventilation Distribution After Bariatric Surgery
Obese patients have an increased risk of developing post-operative respiratory complications due to their comorbidities. They have a restrictive ventilatory defect with reduction of lung volumes and expiratory flow limitation…
- Trial name
- NCT03975348
- Testing
- High flow nasal cannula, Continuous positive airway pressure, Facemask
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- University of Trieste
Atelectasis, Pediatric Anesthesia
Atelectasis After Inhalation or Intravenous Induction in Pediatric Anesthesia
Children have a highly compliant chest wall and atelectasis formation occurs often during pediatric anesthesia. Inhalation induction is commonly performed in pediatric anesthesia but it is still unclear if this can have an effect…
- Trial name
- AtelectLUS (NCT06069414)
- Testing
- Type of anesthesia induction
- Where
- Italy
- Volunteers
- 326 people
- Sponsor
- Vittore Buzzi Children's Hospital
Pulmonary Atelectasis
Interest of Positive Expiratory Pressure (PEP) Delivery by EzPAP® After Cardiac Surgery in the Management of Postoperative Atelectasis
Pulmonary atelectasis is a frequent respiratory postoperative complication in cardiac surgery. Classically, the treatment of these patients is based on manual chest physiotherapy.
- Trial name
- PEPKIN (NCT02262182)
- Testing
- KP group, KM group
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Nantes University Hospital
Respiratory Distress Syndrome of Newborn
Modified Intubation-surfactant-extubation (InSurE) Technique in Preterm Neonates With Respiratory Distress Syndrome
This study evaluates the less invasive surfactant administration (LISA) combined with synchronized nasal intermittent positive pressure ventilation (SNIPPV) technique in the treatment of respiratory distress syndrome (RDS) of…
- Trial name
- NCT03989960
- Testing
- LISA+SNIPPV, traditional InSurE
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Atelectasis
High Fresh Gas Flow After Intubation
Atelectasis is common during and after general anesthesia. Atelectasis develops early if preoxygenation with 100% oxygen is used and continuously used during induction until endotracheal intubation.
- Trial name
- NCT02216006
- Testing
- Control group, conventional ventilatory settings, High fresh gas flow, high minute ventilation
- Where
- Sweden
- Volunteers
- 24 people
- Sponsor
- Region Västmanland
Brain Ischemia, Reduction of Cerebral Air Emboli
Comparative Effectiveness of Unilateral vs. Bilateral Pulmonary Collapse in Cardiac De-airing
To compare the effectiveness of unilateral pulmonary collapse (right lung) to bilateral pulmonary collapse for cardiac de-airing in open left-sided heart surgery.
- Trial name
- NCT02119871
- Testing
- Bilateral Open Pleurae, Right Pleura Open
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Lund University
Anesthesia, Pulmonary Atelectasis
Impact of an Open Lung Extubation Strategy on Postoperative Pulmonary Complications
Perioperative respiratory complications are a major source of morbidity and mortality. Postoperative atelectasis plays a central role in their development.
- Conditions
- Anesthesia, Pulmonary Atelectasis, Complication of Anesthesia
- Trial name
- NCT04993001
- Testing
- Open lung extubation, Conventional extubation
- Where
- Canada
- Volunteers
- 69 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Pulmonary Atelectasis, Patient Comfort
HFNC During Awake Craniotomy - Impact on Patient Comfort
Background: Patients undergoing awake brain surgery are exposed to non-humidified, non-warmed oxygen/air mix flow through a face mask for a prolonged duration.
- Trial name
- NCT03763461
- Testing
- HFNC, Oxygen Mask
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Western University, Canada
Neonatal Respiratory Distress
Lung Ultrasound in Neonatal Intensive Care Units
Identification of lung diseases causing neonatal respiratory distress by lung ultrasound as a tool that can replace x-ray .
- Trial name
- NCT06372951
- Testing
- Ultrasound
- Volunteers
- 132 people
- Sponsor
- Assiut University
Premature Lungs, Respiratory Distress Syndrome
Early Caffeine and LISA Compared to Caffeine and CPAP in Preterm Infants
This study is being conducted to determine whether prophylactic administration of surfactant by the Less Invasive Surfactant Administration (LISA) method reduces the need for mechanical ventilation in the first 72 hours of life…
- Conditions
- Premature Lungs, Respiratory Distress Syndrome, Surfactant Deficiency Syndrome Neonatal
- Trial name
- CaLI (NCT04209946)
- Testing
- Less Invasive Surfactant Administration LISA, Continuous Positive Airway Pressure CPAP
- Where
- 3 sites in United States
- Volunteers
- 180 people
- Sponsor
- Sharp HealthCare
Atelectasis, Postoperative
Lung Recruitment in Laparoscpic Surgery
The goal of this clinical trial study is to assess the effectiveness of different methods of lung recruitment maneuver on the incidence of atelectasis in adults undergoing laparoscopic cholecystectomy surgery using lung…
- Trial name
- NCT06221449
- Testing
- Positive end expiratory pressure
- Where
- Egypt
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Collapsed Lung
Sonographic Assessment of Postural Lung Recruitment in Pediatric Patients Under General Anesthesia
Anesthesia-induced atelectasis is a well-known entity observed in approximately 68-100% of pediatric patients undergoing general anesthesia.
- Trial name
- NCT03141515
- Testing
- Lung ultrasound
- Where
- Argentina
- Volunteers
- 40 people
- Sponsor
- Hospital Privado de Comunidad de Mar del Plata