Clinical trials: Pulmonary Atelectases
CABG
Effects of Acapella VS CHEST Physiotherapy in Post-Operative CABG Patients
Coronary artery bypass grafting (CABG) is a surgical procedure that is performed to improve blood flow to the heart by bypassing blocked or narrowed arteries.
- Trial name
- NCT06317363
- Testing
- Base Line + ACEPELLA, Base Line + Manual Chest Physiotherapy
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Segmental Lung Atelectasis
Segmental Lung Recruitment: a Randomized Controlled Trial
This study compares two ways of reopening collapsed parts of the lung in patients on a ventilator. In one group, doctors use a small camera (bronchoscope) to guide air pressure directly to the blocked part of the lung.
- Trial name
- NCT07442708
- Testing
- Segmental lung recruitment, Conventional lung recruitment
- Volunteers
- 20 people
- Sponsor
- Clinical Hospital Center Rijeka
Atelectasis
Effect of Spontaneous Breathing on Atelectasis During Induction of General Anesthesia in Patients in Infants
spontaneous breathing on occurrence of atelectsis in infants
- Trial name
- NCT03739697
- Testing
- spontaneous breathing
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Anesthesia, General, Pulmonary Atelectasis
High-flow Nasal Oxygenation During Preoxygenation and Atelectasis
Atelectasis after induction of general anesthesia is common even in healthy patients and is clinically problematic, especially in obese patients.
- Trial name
- NCT06205212
- Testing
- high-flow nasal oxygen, facemask
- Where
- South Korea
- Volunteers
- 92 people
- Sponsor
- Seoul National University Hospital
Atelectasis, Compliance, Patient
Restoration of Pulmonary Compliance After Laparoscopic Gynaecologic Surgery Using a Recruitment Maneuver
To investigate the hypothesis that an alveolar recruitment maneuver after the release of pneumoperitoneum would restore the lung compliance to the baseline values after a laparoscopic gynaecologic surgery.
- Trial name
- NCT06203665
- Testing
- Recruitment Maneuver
- Where
- Greece
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Panagiota Griva
Lung Collapse
The Effect of Lateral Tilt on Ventilation Distribution in Lungs Assessed by Electrical Impedance Tomography
Prevention of lung inhomogeneity is an essential part of preventive strategy in neurocritical care, reducing the risks of secondary brain damage from hypoxemia, hypo/hypercapnia or pneumonia.
- Trial name
- N-LAT-EIT (NCT04235231)
- Testing
- Bed tilting, Body positioning
- Where
- Czechia
- Volunteers
- 250 people
- Sponsor
- Regional Hospital Liberec
Atelectasis, Oxygenation
Zero Positive End-expiratory Pressure Before Emergence Prevents Postoperative Atelectasis.
A study on healthy patients undergoing anesthesia for non-abdominal surgery - evaluation of positive end-expiratory pressure versus zero positive end-expiratory pressure on the amount of atelectasis in the early postoperative…
- Trial name
- NCT03351946
- Testing
- ZEEP, PEEP
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Region Västmanland
Moderate Persistent Asthma, Severe Persistent Asthma
Expressions of TRPV1 in Airway of Asthmatics
The purpose of this study is to measure the density of a temperature-sensitive protein, named TRPV1, in the airway mucosa tissue of both non-asthmatic and moderate to severe persistent asthmatic patients.
- Conditions
- Moderate Persistent Asthma, Severe Persistent Asthma, Nodule Solitary Pulmonary, Pulmonary Atelectasis
- Trial name
- TRPV1 (NCT02952066)
- Testing
- Bronchial biopsy
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Lu Yuan Lee
Atelectasis, Pulmonary Complications
Low-Flow Anesthesia and Perioperative Atelectasis in Laparoscopic Bariatric Surgery
The goal of this clinical trial is to learn whether low-flow anesthesia reduces perioperative atelectasis compared to normal-flow anesthesia in adults undergoing laparoscopic bariatric surgery.
- Conditions
- Atelectasis, Pulmonary Complications, Ultrasonography, Bariatric Surgery
- Trial name
- NCT07041567
- Testing
- Sevoflurane with normal-flow anesthesia, Sevoflurane with low-flow anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University
Bleeding, Hypoxia
Video-guided Percutaneous Tracheostomy (PCT): A Feasibility Study
The purpose of this study is to determine the feasibility, safety and effectiveness of an endotracheal tube embedded with a mini video-camera as a guiding tool for percutaneous tracheostomy.
- Conditions
- Bleeding, Hypoxia, Atelectasis, Pneumothorax
- Trial name
- NCT01013298
- Testing
- video-guided PCT
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Atelectasis, Oxygenation
Estimation of Perioperative Atelectasis
This study will compare an oxygenation test based on arterial blood gas analysis with computed tomography for estimating the extent of atelectasis.
- Trial name
- NCT03352336
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Region Västmanland
Infant, Preterm, Respiratory Distress Syndrome (Neonatal)
Pulmonary Volume Changes During Synchonized Noninvasive Positive Pressure Ventilation
Current evidence suggests that noninvasive positive pressure ventilation (NIPPV) is more effective than continuous positive airway pressure (CPAP) in preventing respiratory failure in preterm infants with respiratory distress…
- Conditions
- Infant, Preterm, Respiratory Distress Syndrome (Neonatal), Chronic Lung Disease of Newborn, Respiratory Support
- Trial name
- INSPIRE (NCT07237139)
- Testing
- Electrical Impedance Tomography (EIT)
- Where
- Switzerland
- Volunteers
- 27 people
- Sponsor
- University of Zurich
Ventilator-associated Lung Injury, Atelectasis
Comparing Innovative and Traditional Ventilation Strategies on Atelectasis and Prognosis in Elderly Patients
This study was divided into two parts, taking elderly patients undergoing general anesthesia surgery as the research subjects, through factorial design: 1.
- Conditions
- Ventilator-associated Lung Injury, Atelectasis, Postoperative Pulmonary Complications
- Trial name
- NCT06021249
- Testing
- Traditional ventilation strategies, Traditional lung-protective ventilation strategies, Innovative lung-protective ventilation strategies
- Where
- 3 sites in China
- Volunteers
- 304 people
- Sponsor
- Fujian Medical University Union Hospital
Postoperative Respiratory Complication, Atelectasis
Positive-Pressure vs Suction Extubation in Cesarean Patients
This randomized controlled trial aims to evaluate the effects of two tracheal extubation techniques on postoperative oxygenation and early respiratory outcomes in adult women undergoing elective cesarean delivery under general…
- Conditions
- Postoperative Respiratory Complication, Atelectasis, Anesthesia, General, Extubation
- Trial name
- PPET (NCT07251686)
- Testing
- Negative Pressure Extubation Technique (NPET), Positive Pressure Extubation Technique (PPET)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Medipol University
Dyspnea, Respiratory Rate
Evaluating the Effectiveness of Incentive Spirometry
Post-operative pulmonary complications (PPCs) have a major impact on patients and healthcare expenses. The goal of perioperative respiratory therapy is to improve airway clearance, increase lung volume, and mitigate atelectasis.
- Conditions
- Dyspnea, Respiratory Rate, Oxygen Saturation, Oxygen Requirements
- Trial name
- NCT02952027
- Testing
- Use-recording, patient-reminder alarm for incentive spirometry
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Lifespan
Postoperative Pulmonary Atelectasis, Postoperative Pulmonary Complications
Driving Pressure During Surgeries With High Risk for Postoperative Pulmonary Complications
The goal of this clinical trial is to compare two different types of perioperative mechanical ventilation (MV), specifically Protective Mechanical Ventilation (PMV) and MV with the lowest possible Driving Pressure (ΔP), in…
- Conditions
- Postoperative Pulmonary Atelectasis, Postoperative Pulmonary Complications, Postoperative Respiratory Failure, Postoperative Bronchospasm
- Trial name
- NCT07186933
- Testing
- PEEP titration for Minimum Driving Pressure, Lung Protective Ventilation
- Where
- Greece
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University General Hospital of Patras
Respiratory Distress Syndrome of Newborn
A Clinical Pharmacological Study of Dose Halving of Dexamethasone in Pregnant Women With Preterm Labour With Preterm Birth at Greater Than or Equal to 34 Gestational Weeks (34GW+)
This study plans to conduct a DEX dose halving study and a normal dose study in 34+0-35+6 GW women with preterm preterm labour. In addition, this study plans to conduct a DEX dose halving study and a normal dose study in 34-38+6…
- Trial name
- NCT06350565
- Testing
- Dexamethasone
- Volunteers
- 48 people
- Sponsor
- Peking University Third Hospital
Atelectasis
Effects of Pneumoperitoneum on Dynamic Alveolar Stress-strain in Anesthetized Pediatric Patients
General anesthesia is associated with loss of pulmonary functional residual capacity and consequent developement of atelectasis and closure of the small airway.
- Trial name
- NCT04183309
- Testing
- Measure the transpulmonary pressure in pediatric patients
- Where
- Argentina
- Volunteers
- 20 people
- Sponsor
- Hospital Privado de Comunidad de Mar del Plata
Obesity, Abdominal, Anesthesia Morbidity
CPAP in Patients With Severe Obesity After Anesthesia
The goal of this study is to compare two continuous positive airway pressure (CPAP) settings on heart and lung function in patients with severe obesity after anesthesia. The main questions it aims to answer are: 1.
- Conditions
- Obesity, Abdominal, Anesthesia Morbidity, Apnea, Obstructive Sleep, Atelectases, Postoperative Pulmonary
- Trial name
- NCT06287632
- Testing
- Recruitment/ITP-CPAP (Intervention A), Standard CPAP (Intervention B), Atmospheric Pressure
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Atelectasis, Pneumonia
Role of Lung Ultrasound and Pulsed-wave Doppler in Lung Consolidations in Mechanically Ventilated Patients
In infectious lung consolidations, the inhibition of hypoxic pulmonary vasoconstriction (HPV) results in a higher regional acceleration time (RAcT) compared to the RAcT measured in atelectatic consolidations.
- Trial name
- NCT02100449
- Testing
- Lung ultrasound and Doppler (Day 0)
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)