Clinical trials: Pulmonary Atelectases
Surfactant Deficiency Syndrome Neonatal
Premedication for Less Invasive Surfactant Administration
Early respiratory management of preterm infants immediately after birth should be as gentle as possible. With this so-called developmental approach, unnecessary invasive methods can be avoided or at least postponed.
- Trial name
- LISA-Med (NCT03735563)
- Testing
- Ketamine, Fentanyl
- Where
- Finland
- Volunteers
- 40 people
- Sponsor
- University of Oulu
Malignant Neoplasms of Respiratory and Intrathoracic Organs, Lung Neoplasm
Radial-Probe Endobronchial Ultrasound in Detecting Atelectasis in Patients Undergoing Peripheral Bronchoscopy
This trial studies how well radial-probe endobronchial ultrasound works in detecting the complete or partial collapse of the lung in patients undergoing peripheral bronchoscopy.
- Trial name
- NCT03523689
- Testing
- Bronchoscopy, Radial Probe Endobronchial Ultrasound
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- M.D. Anderson Cancer Center
Pregnancy Complications, Atelectasis
Effect of Epidural Analgesia on Regional Lung Ventilation in Parturient Women as Assessed by Thoracic Impedance
The goal of this observational study is to learn more about the effect of obstetric epidural anesthesia on regional lung ventilation in healthy parturient women.
- Trial name
- NCT06195774
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Erasme University Hospital
Atelectasis, Pulmonary Complications
Evaluation of The MetaNeb® System to Reduce Postoperative Pulmonary Complications
To determine if a therapy regimen including treatment with The MetaNeb® System had a positive impact on the rate of pulmonary complications related to atelectasis and/or secretion retention that occur in high risk post-operative…
- Trial name
- NCT02627742
- Testing
- MetaNeb® System
- Where
- 3 sites in United States
- Volunteers
- 419 people
- Sponsor
- Hill-Rom
Atelectasis, Mechanical Ventilation
Effects of Periodic Recruitment Maneuvers on Atelectasis and Respiratory Mechanics During Elective Spine Surgery Assessed by Lung Ultrasonography
During general anesthesia, particularly in patients undergoing spine surgery in the prone (face-down) position, increased intrathoracic and abdominal pressure may reduce lung compliance and promote the development of atelectasis…
- Conditions
- Atelectasis, Mechanical Ventilation, General Anesthesia, Prone Position
- Trial name
- NCT07325812
- Testing
- Alveolar Recruitment Maneuver
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
COVID-19, Fatigue
Differential Diagnosis of Persistent COVID-19 by Artificial Intelligence
The pandemic caused by SARS-CoV-2 infection has resulted, in addition to the well-known acute symptoms, in the emergence of persistent, diffuse and heterogeneous symptoms referred to as persistent COVID.
- Conditions
- COVID-19, Fatigue, Distress Respiratory Syndrome, Cognitive Dysfunction
- Trial name
- DICOPERIA (NCT05629793)
- Testing
- Experimental tests
- Where
- 7 sites in Spain
- Volunteers
- 136 people
- Sponsor
- Fundacin Biomedica Galicia Sur
Obesity (Body Mass Index >30 kg/m2), Atelectasis, Postoperative
Dynamic Compliance-Guided Personalized PEEP During Laparoscopic Bariatric Surgery: Effects on Intraoperative Respiratory Parameters
Atelectasis may be encountered in the patient population aged 18-65 years undergoing elective laparoscopic bariatric surgery under general anesthesia with endotracheal intubation.
- Conditions
- Obesity (Body Mass Index >30 kg/m2), Atelectasis, Postoperative, PEEP With Dynamic Compliance, Individualized PEEP
- Trial name
- NCT07345650
- Testing
- Individualized approach
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Yeditepe University
Video-assisted Thoracoscopic Surgery (VATS), Lung Cancer (Diagnosis)
Intraoperative Paravertebral Block and Postoperative Complications
This study aims to evaluate the clinical association between intraoperative paravertebral block and the reduction of postoperative complications following thoracic surgery.
- Conditions
- Video-assisted Thoracoscopic Surgery (VATS), Lung Cancer (Diagnosis), Pulmonary Infections, Respiratory Failure Without Hypercapnia
- Trial name
- IPVB and POCs (NCT07211529)
- Testing
- Paravertebral Block (PVB)
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Tongji Hospital
Pulmonary Atelectasis
Effect of Recruitment Maneuver on Postoperative Atelectasis Assessed by Lung Ultrasound in Laparoscopic Cholecystectomy
This single-centre, prospective, randomized, parallel-group controlled trial evaluated whether alveolar recruitment manoeuvres (RMs) added to a lung-protective ventilation strategy improve perioperative lung aeration in adults…
- Trial name
- LUNG USG SCORE (NCT07324122)
- Testing
- Alveolar recruitment manoeuvre, Lung-protective ventilation with lung ultrasound assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Respiratory Failure, Atelectasis
Low Tidal MEChanical Ventilation Against NO Ventilation During Cardiopulmonary Bypass Heart Surgery
BACKGROUND. Postoperative pulmonary complications are a leading cause of morbidity and mortality after cardiac surgery. To this date, there are no recommendations regarding mechanical ventilation associated with cardiopulmonary…
- Conditions
- Respiratory Failure, Atelectasis, Pneumonia, Pneumothorax
- Trial name
- MECANO (NCT03098524)
- Testing
- Low tidal volume ventilation (LTV arm), No ventilation (noV arm), Lung recruitment manoeuver
- Where
- France
- Volunteers
- 1,502 people
- Sponsor
- CMC Ambroise Paré
Neonatal Respiratory Distress
DIaphragmatic Swing According to Cpap Flow Output in NEOnates (DISCONEO)
The hypothesis behind the study is that the performance of constant flow CPAP (Continuous Positive Airway Pressure) devices (CF-CPAP) is not inferior to that of variable flow CPAP devices (VF-CPAP) in terms of respiratory efforts…
- Trial name
- NCT07513051
- Testing
- CF-CPAP; CF-CPAP; VF-CPAP; VF-CPAP, VF-CPAP; VF-CPAP; CF-CPAP; CF-CPAP, CF-CPAP; VF-CPAP; VF-CPAP; CF-CPAP
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Neoplasms, Pulmonary, Thoracic Diseases
The Need of Fiberoptic Bronchoscopy for Placing an Endobronchial Blocker
The need of fiberoptic bronchoscopy for placing an endobronchial blocker. Endobronchial blockers (EBB) have been presented effective and safe alternative for lung separation in vedio-assisted thoracoscopic (VATS) operations.
- Trial name
- NCT02133235
- Testing
- conventional, auscultation
- Where
- Taiwan
- Volunteers
- 112 people
- Sponsor
- National Taiwan University Hospital
Postoperative Pulmonary Atelectasis, Morbid Obesity
Perioperative Diaphragmatic Ultrasound as Predictive Index of Atelectasis in Bariatric Surgery
In this study the Authors assume that peri-operative changes in DIA are predictive of postoperative atelectasis, thus providing a clinically useful tool to stratify the need for high-intensity monitoring, including admission to…
- Trial name
- ECODIA (NCT04701541)
- Testing
- Diaphragmatic Ultrasound
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Roma La Sapienza
Pulmonary Atelectasis, Postoperative
Individual Optimal Positive End-expiratory Pressure During Robot-assisted Laparoscopic Radical Prostatectomy
During robot-assisted radical prostatectomy, pneumoperitoneum with Trendelenburg position is used. However, perioperative atelectasis and respiratory complications may occur with high incidence due to general anesthesia and…
- Trial name
- NCT04085146
- Testing
- Individualized optimal positive end-expiratory pressure, Conventional positive end-expiratory pressure
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Lung Collapse
Brochoscopic Intervention Versus Conventional Management in Acute Lung Collapse in the Pediatric Intensive Care Unit
This prospective RCT at Cairo University Children Hospitals enrolls critically ill pediatric patients (intubated, NIV, or post-extubation) with lung atelectasis unresponsive to 48 hours of conventional recruitment.
- Trial name
- picu (NCT07383129)
- Testing
- bronchoscope, chest physiotherapy and suction
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Cairo University
Pneumothorax, Pulmonary Nodule, Solitary
Multi-Reader Retrospective Study Examining Carebot AI CXR 2.0.21-v2.01 Implementation in Everyday Radiology Clinical Practice
The primary objective is to evaluate the performance parameters of the proposed DLAD (Carebot AI CXR) in comparison to individual radiologists.
- Conditions
- Pneumothorax, Pulmonary Nodule, Solitary, Atelectasis, Subcutaneous Emphysema
- Trial name
- NCT05963945
- Testing
- Carebot AI CXR
- Where
- Czechia
- Volunteers
- 956 people
- Sponsor
- Carebot s.r.o.
Weaning Failure, Pulmonary Collapse
Lung Volume Preservation During Extubation
Introduction: At present, the best spontaneous breathing trial (SBT) during weaning from mechanical ventilation is a 30-min test with pressure support (PSV) 8 cmH2O without positive end-expiratory pressure (PEEP).
- Trial name
- NCT05526053
- Testing
- Lung volume preservation
- Where
- Spain
- Volunteers
- 1,753 people
- Sponsor
- Althaia Xarxa Assistencial Universitària de Manresa
Lung Collapse
Abdominal Pressure Assessment Following Open Abdominal Surgery
During abdominal surgery, the intra abdominal pressure may increase determining lung bibasal atelectasis. The investigators hypothesized that the application of Positive End Expiratory Pressure (PEEP) promptly after extubation…
- Trial name
- AbdoPress (NCT03369483)
- Testing
- Abdominal pressure assessment
- Where
- 5 sites in Italy
- Volunteers
- 100 people
- Sponsor
- University Magna Graecia
Atelectasis, Postoperative Pulmonary
Evaluation of the Effects of Intraoperative Ventilation Modes on Perioperative Atelectasis
In hysterectomy surgeries, due to factors such as the abdominal nature of the procedure, prolonged operative duration, and the use of the head-down (Trendelenburg) position during surgery, a lobe or a specific region of the lungs…
- Trial name
- NCT07413575
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Alveolar Recruitment Maneuvers, Atelectasis
Alveolar Recruitment Maneuvers on Reduction of Lung Atelectasis in Bariatric Surgery by Using Lung Ultrasound Score
The study aims to compare the staircase alveolar recruitment maneuver with PEEP titration versus sustained inflation alveolar recruitment maneuver by using lung ultrasound score as an indicator of improving lung atelectasis in…
- Conditions
- Alveolar Recruitment Maneuvers, Atelectasis, Bariatric Surgery
- Trial name
- NCT05720351
- Testing
- Lachmann maneuver, Staircase maneuver
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University