Clinical trials: Pulmonary Disease (COPD), Chronic Obstructive
Pulmonary Disease, Chronic Obstructive
A Study Using US Medical and Pharmacy Claim Records to Compare the Resource Use, Cost, and Outcomes of People With COPD Who Take Either Tiotropium + Olodaterol or Fluticasone + Umeclidinium + Vilanterol
The purpose of this study is to estimate disease-related and all-cause burden and clinical outcomes of interest following initiation of chronic obstructive lung disease (COPD) maintenance therapy with Tiotropium…
- Trial name
- NCT05127304
- Testing
- Trelegy Ellipta, Stiolto Respimat, Furoate/Umeclidinium/Vilanterol
- Where
- United States
- Volunteers
- 11,316 people
- Sponsor
- Boehringer Ingelheim
Chronic Obstructive Pulmonary Disease Severe, Dyspnea
Study of the Cytokine Response During Exercise Dyspnea in Patients With Chronic Obstructive Pulmonary Disease (COPD). Effect of Body Composition
Dyspnea, more commonly known as breathlessness, is a symptom found in the majority of patients with chronic obstructive pulmonary disease (COPD), with a major impact on quality of life and mortality.
- Trial name
- CYTODINE (NCT06229509)
- Testing
- Effective noninvasive ventilation
- Where
- France
- Volunteers
- 26 people
- Sponsor
- University Hospital, Clermont-Ferrand
Chronic Obstructive Pulmonary Disease Severe, Muscle Weakness
Additional Manual Therapy Over Inspiratory Muscle Training in COPD
The benefits of inspiratory muscle training(IMT) in patients with chronic obstructive pulmonary disease(COPD) were reported.But in severe COPD patients, benefit from IMT may be limited.There is need for further research in new…
- Trial name
- NCT04533516
- Testing
- Manual therapy technics, Inspiratory Muscle Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istinye University
Invasive Pulmonary Aspergillosis, Chronic Obstructive Pulmonary Disease
Efficacy and Safety of Caspofungin for Invasive Pulmonary Aspergillosis Underlying Chronic Obstructive Pulmonary Disease
The investigators propose to study the efficacy and safety of three-week antifungal therapy with caspofungin in hospitalized patients with proven or probable IPA underlying chronic obstructive pulmonary disease.
- Trial name
- NCT01499433
- Testing
- caspofungin
- Where
- China
- Volunteers
- 40 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD)
Pharmacodynamic and Pharmacokinetic Dose Ranging Study of Tiotropium Bromide Administered Via Inhalation Solution in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Pharmacodynamic and Pharmacokinetic Dose Ranging Study of Tiotropium Bromide Administered Via Inhalation Solution in Patients With Chronic Obstructive Pulmonary Disease (COPD).
- Trial name
- NCT03118765
- Testing
- GSP304 (tiotropium bromide) Inhalation Solution, Spiriva® Respimat® inhalation spray
- Where
- 25 sites in United States
- Volunteers
- 155 people
- Sponsor
- Glenmark Specialty S.A.
Chronic Obstructive Pulmonary Disease, Emphysema
Studying the Airway Microenvironment in Patients Undergoing Surgical and Bronchoscopic Interventions for COPD
Studying the airway microenvironment in patients undergoing surgical and bronchoscopic interventions for COPD
- Conditions
- Chronic Obstructive Pulmonary Disease, Emphysema, Chronic Bronchitis
- Trial name
- COPD-ENVIRON (NCT03010592)
- Where
- 2 sites in United Kingdom
- Volunteers
- 80 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Patient Adherence
Efficacy Of An Education Plan And Adherence Follow-Up To The Exercise In Patients With COPD
Chronic obstructive pulmonary disease is one of the main causes of morbidity and mortality worldwide, according to recent publications of the World Health Organization, its main feature is the response to noxious particles of…
- Trial name
- NCT05204498
- Testing
- Education plan and adherence to exercise
- Where
- Colombia
- Volunteers
- 31 people
- Sponsor
- Clínica de Occidente S.A
Chronic Obstructive Pulmonary Disease, Fall
The Risk of Falling in Patients with Chronic Obstructive Pulmonary Disease
This cross-sectional study aims to investigate what daily activities increase the risk of falling in Chronic Obstructive Pulmonary Disease patients (COPD).
- Conditions
- Chronic Obstructive Pulmonary Disease, Fall, Balance; Distorted, Activity, Motor
- Trial name
- NCT04074499
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Istanbul University - Cerrahpasa
COPD, Emphysema or COPD
Crossover Blinded Trial of Cell Therapy Versus Placebo in COPD
The aim of this randomized, controlled crossover designed study is to compare the outcomes of receiving autologous, adult stem cells versus placebo among participants with chronic obstructive pulmonary disease (COPD).
- Conditions
- COPD, Emphysema or COPD, Chronic Bronchitis
- Trial name
- NCT03228121
- Where
- United States
- Sponsor
- Lung Institute
COPD Exacerbation
Prevalence, Associated Factors Points and Implementation of Care Procedures of Chronic Obstructive Pulmonary Disease Exacerbation in Healthcare Institution
Chronic Obstructive Pulmonary Disease (COPD) is a public health problem responsible for high mortality rate and significant costs for society.
- Trial name
- OPEDEXA (NCT05682404)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Grenoble
Heart Failure, Chronic Obstructive Pulmonary Disease
Coventry Outcomes Study of Seniors (COSS): A Comparative Effectiveness Study to Evaluate the Effect of a Multidisciplinary Team's Intervention on the Incidence of Nonelective Hospitalizations in a Medicare Population
The investigators are studying the impact of the interventions of a multidisciplinary team (MDT) - consisting of a Coventry case manager, social worker, and medical director, alongside a Medco specialist pharmacist - on the…
- Conditions
- Heart Failure, Chronic Obstructive Pulmonary Disease, Cardiovascular Disease, Diabetes
- Trial name
- COSS (NCT01014884)
- Testing
- Multidisciplinary team interventions, Multidisciplinary team bimonthly visits either in person or via telephone., Usual case management and pharmacy management as provided by the health Plan and the pharmacy benefit manager
- Where
- 2 sites in United States
- Volunteers
- 2,150 people
- Sponsor
- Medco Health Solutions, Inc.
Chronic Obstructive Pulmonary Disease
Comorbidities and Healthcare Utilisation: Indicators for Improving COPD Diagnosis
To characterise and understand the current UK COPD population including demographics, active comorbidities and missed opportunities for COPD diagnosis in the years previous to diagnosis
- Trial name
- NCT01655667
- Where
- United Kingdom
- Volunteers
- 38,859 people
- Sponsor
- Research in Real-Life Ltd
COPD, COPD Exacerbation
Supported Rescue Packs Post-discharge in Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) is a chronic lung disease affecting approximately 10% of the adult population globally.
- Trial name
- RAPID (NCT06347536)
- Testing
- Supported rescue pack
- Where
- 34 sites in United Kingdom
- Volunteers
- 1,400 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Chronic Obstructive Pulmonary Disease
Safety, Tolerability, and Pharmacodynamic Effect Study of PUR118
The purpose of this study is to establish single and multiple dose safety in healthy subjects and subjects with mild chronic pulmonary obstructive disease (COPD).
- Trial name
- NCT01333904
- Testing
- PUR118
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Pulmatrix Inc.
Pulmonary Disease, Chronic Obstructive
Carbon Dioxide Rebreathing During Exercise Assisted by Non-invasive Ventilation
The purpose of this study was to evaluate whether CO2 rebreathing occurs in healthy subjects or patients with COPD ventilated during exercise assisted by the single-limb circuit with a plateau exhalation valve at a given…
- Trial name
- NCT02655484
- Testing
- BiPAP® Vision® ventilator（"Ventilator", "Philips Respironics™ BiPAP® Vision®" ）
- Where
- China
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Guangzhou Institute of Respiratory Disease
COPD
The Effect of Fluticasone/Salmeterol Combination on Exertional Breathlessness in Patients With Mild COPD
Even patients with milder COPD can have significant physiological abnormalities which become more pronounced during exercise, leading to intolerable breathing discomfort (dyspnea).
- Trial name
- NCT00559312
- Testing
- fluticasone/salmeterol combination
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- Queen's University
Parkinson Disease (PD), Chronic Heart Failure (CHF)
An Innovative Disease-net Management Model for Non-communicable Diseases (SIDERA^B)
The SIDERA^B telerehabilitation system is enabled by a multi-domain, multi-device platform providing at home multi-component rehabilitation, targeting cardiovascular (Chronic Heart Failure, CHF), pulmonary (Chronic Obstructive…
- Conditions
- Parkinson Disease (PD), Chronic Heart Failure (CHF), Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- SIDERA^B (NCT04041193)
- Testing
- SIDERA^B, Usual Care Program
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
COPD
Study to Evaluate the Efficacy and Safety of Glycopyrronium or Indacaterol Maleate and Glycopyrronium Bromide Fixed-dose Combination Regarding Symptoms and Health Status in Patients With Moderate COPD Switching From Treatment With Any Standard COPD Regimen
The main goal of this study is to evaluate the efficacy and safety of glycopyrronium bromide and indacaterol maleate and glycopyrronium bromide fixed dose combination (FDC) in patients with moderate COPD who switch from their…
- Trial name
- NCT01985334
- Testing
- Glycopyrronium, SABA, LABA
- Where
- 542 sites in Austria, Belgium and 21 more
- Volunteers
- 4,389 people
- Sponsor
- Novartis Pharmaceuticals
Pulmonary Disease, Chronic Obstructive
Observational Non-Interventional Study With Spiriva Respimat in COPD Patients
This observational non-interventional study is designed to demonstrate the improvement of physical function in COPD patients on treatment with Spiriva Respimat and allows adverse events to be recorded and evaluated.
- Trial name
- NCT00699699
- Where
- 188 sites in Germany
- Volunteers
- 1,280 people
- Sponsor
- Boehringer Ingelheim
Chronic Obstructive Pulmonary Disease
A Cross Sectional Disease/Condition Focused Observational Study on Chronic Obstructive Pulmonary Disease (COPD)
The purpose of this study is to establish the prevalence of comorbidities in Italian patients with chronic bronchitis with at least 2 exacerbations per year, and to document the appropriateness of instrumental diagnostic tests…
- Trial name
- PREFER (NCT02100332)
- Where
- Italy
- Volunteers
- 860 people
- Sponsor
- AstraZeneca
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