Clinical trials: Pulmonary Disease (COPD), Chronic Obstructive
COPD, Chronic Musculoskeletal Pain
BRAIN, Symptoms, and Physical Activity in COPD
Persons with COPD have both chronic musculoskeletal pain and dyspnea that require accurate diagnosis and treatment, ultimately to optimize functional status.
- Trial name
- BRAIN-SPA (NCT04291131)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- VA Office of Research and Development
COPD Chronic Obstructive Pulmonary Disease, Interstitial Lung Disease
Assessing Functional Capacity in Directly and Remotely Monitored Home-based Settings: A Protocol for a Multinational Validation Study in Individuals With Chronic Respiratory Diseases
The goal of this validation study is to provide further evidence of the metrological properties of the 6-minute stepper test in individuals with chronic obstructive pulmonary disease (COPD) or interstitial lung disease (ILD).
- Trial name
- 6MST (NCT06447831)
- Where
- 3 sites in Canada, France
- Volunteers
- 89 people
- Sponsor
- Laval University
COPD
The Prevalence of Chronic Pain in COPD and Its Clinical Implications
This study explores the prevalence of chronic pain in individuals with COPD compared to healthy controls and examines the clinical implications of pain on symptoms associated with COPD, psychological effect and physical activity.
- Trial name
- NCT05366946
- Testing
- Prevalence study
- Where
- Canada
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- West Park Healthcare Centre
COPD
Respiratory Muscle Exercise Training in COPD Patients
COPD patients often suffer from dyspnea and exercise intolerance which lower their quality of life.The aim of this proposed study is to examine the effectiveness of multi-respiratory muscle training on respiratory function of…
- Trial name
- NCT01747694
- Testing
- Multi-respiratory muscle training
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
Asthma, Copd
Monitoring Metered Dose Inhalation (MDI) Volume and Timing With a Respimetrix Device in Obstructive Lung Disease.
To Determine whether use of the Respimetrix flow test device a) can determine "good" versus "poor" inhaler techniques, and b) the effects of the inhaler training on technique.
- Trial name
- NCT05495256
- Testing
- Respimetrix
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Pulmonary Critical Care Associates of Baltimore
Alpha 1-Antitrypsin Deficiency, Emphysema or COPD
PiMZ Longitudinal Cohort (PiMZ Logic)
Alpha-1 Anti-trypsin Deficiency (AATD) is a genetic disease with lung and liver disease presentations. Presentations are variable in the heterozygous population, the most predominant genotype being PiMZ.
- Trial name
- NCT06505603
- Where
- 5 sites in United States
- Volunteers
- 80 people
- Sponsor
- Columbia University
COPD
Anti-inflammatory Effects of Tiotropium in Patients with Stable COPD
This study aims to assess the anti-inflammatory effects after 6 weeks treatment with tiotropium compared to placebo in patients with stable COPD
- Trial name
- ANTIOFLAM (NCT04061161)
- Testing
- Tiotropium Bromide
- Where
- 2 sites in Netherlands
- Volunteers
- 37 people
- Sponsor
- University Medical Center Groningen
Asthma
Study to Evaluate the Pharmacokinetic Profile of Salbutamol Delivered by Unit Dose Dry Powder Inhaler (UD-DPI) Compared to the Diskus and Metered Dose Inhaler (MDI) in Healthy Volunteers.
This is an open-label, two part, six period- cross over, randomised, single dose, single centre study in healthy subjects. This is the first clinical study for the UD-DPI. This study is divided into two parts.
- Trial name
- NCT01984086
- Testing
- Salbutamol Sulphate 150mcg UD-DPI Blister(1.6% blend), Salbutamol Sulphate 200mcg UD-DPI Blister(1.6% blend), Salbutamol Sulphate 250mcg UD-DPI Blister(1.6% blend)
- Where
- Australia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Chronic Obstructive Pulmonary Disease
Chronic Airway Disease, Mucus Rheology and Exacerbations
The main objective of this trial is to compare the exacerbation number over 12 months of follow-up between a group of patients with COPD treated according to standardized management (azithromycin prescribed in the event of severe…
- Trial name
- COPD-CARhE (NCT04339270)
- Testing
- Azithropycin according to symptoms, Azithromycin according to rheology or symptoms
- Where
- 3 sites in France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Montpellier
Chronic Obstructive Pulmonary Disease
Pulmonary Rehabilitation Program and PROactive Tool
Pulmonary rehabilitation is an essential non pharmacological treatment option which reduces dyspnea sensations, increase exercise tolerance, improves health related quality of life and reduces the burden on health care resources…
- Trial name
- PROactive (NCT02437994)
- Testing
- Pulmonary Rehabilitation
- Where
- Greece
- Volunteers
- 115 people
- Sponsor
- Thorax Research Foundation
Chronic Obstructive Pulmonary Disease
An Evaluation of Web Based Pulmonary Rehabilitation
The purpose of this pilot study is to compare a six week web-based pulmonary rehabilitation programme with traditional hospital-based pulmonary rehabilitation classes for people affected by COPD.
- Trial name
- webbasedPR (NCT02404831)
- Testing
- Web-based PR, Hospital-based PR
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Glasgow
Chronic Pulmonary Disease
Pulmonary TELE-REHABilitation Program : Feasibility and Safety Study
Chronic pulmonary disease like interstitial lung disease (ILD) and chronic obstructive lung disease (COPD) are a significant health problem in Canada and around the world.
- Trial name
- Tele-RehaB (NCT04658979)
- Testing
- Pulmonary tele-rehabilitation
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec
Copd, Chest Disorders
Efficacy of Costal Mobilization Techniques and Manual Diaphragm Release Technique in Patients COPD
To evaluate the acute and chronic effects of costal mobilization techniques and diaphragmatic release in chest cavity kinematics, diaphragmatic mobility and functional capacity in patients with chronic obstructive pulmonary…
- Conditions
- Copd, Chest Disorders, Diaphragmatic Disorder
- Trial name
- NCT03022942
- Testing
- GROUP Costal mobilization & Diaphragm Release, GROUP Manual Diaphragm Release
- Where
- Brazil
- Volunteers
- 14 people
- Sponsor
- Universidade Federal de Pernambuco
COPD, Microbial Colonization
Partially Hydrolyzed Guar Gum (PHGG) for Amelioration of Chronic Obstructive Pulmonary Disease (COPD)
Some components of the diet could promote the growth of certain bacterial strains present in the intestine, which are closely associated with benefits for host health.
- Conditions
- COPD, Microbial Colonization, Respiratory Tract Disease
- Trial name
- NCT05126654
- Testing
- Partially Hydrolyzed Guar Gum (PHGG)
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fu Jen Catholic University Hospital
Chronic Obstructive Pulmonary Disease
Impact of a Hospital Physical Therapy Program on Chronic Obstructive Pulmonary Disease (COPD) Patients
The Chronic Obstructive Pulmonary Disease is a leading global cause of morbidity and mortality, so it's important to find actions that could improve quality of life and decrease the mortality.
- Trial name
- NCT01295359
- Testing
- Ground Walking Program
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Universidade Federal de Sao Carlos
Chronic Obstructive Pulmonary Disease
Effectiveness of Antibiotic Therapy for Exacerbations of Chronic Obstructive Pulmonary Disease
The purpose of this study is to determine the effectiveness of antibiotic therapy for patients with acute exacerbations of mild-to-moderate chronic obstructive pulmonary disease.
- Trial name
- TRANCE (NCT00495586)
- Testing
- Amoxicillin and clavulanic acid
- Where
- 13 sites in Spain
- Volunteers
- 318 people
- Sponsor
- Societat Catalana de Medicina Familiar i Comunitària, Assoc. (CAMFiC)
Chronic Obstructive Pulmonary Disease
Do Educational Digital Films Enhance Patient COPD Outcomes?
This study aims to assess the efficacy of Pocket Medic to promote self-management and pulmonary rehabilitation adherence in COPD patients.
- Trial name
- NCT03263754
- Testing
- Pocket Medic, Pulmonary Rehabilitation
- Where
- 2 sites in United Kingdom
- Volunteers
- 55 people
- Sponsor
- Aberystwyth University
Chronic Obstructive Pulmonary Disease, Asthma
Video vs. TTG Respiratory Inhaler Technique Assessment and InstructioN (V-TRaIN)
The purpose of this study is to evaluate the effectiveness of two different ways to teach subjects while hospitalized how to use respiratory inhalers and to follow-up after discharge home from the hospital to determine durability…
- Trial name
- NCT02611531
- Testing
- Video Module Education (VME), Teach-To-Goal (TTG)
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- University of Chicago
Respiratory Insufficiency, Respiratory Distress Syndrome, Adult
Continuous Positive Airway Pressure (CPAP) Ventilation Using a Novel Full-Face Mask Versus Conventional Helmet
The aim of this study is to compare two methods of delivery of noninvasive mechanical ventilation (NIV). Since patient compliance and mechanical characteristics of the delivery devices are two fundamental variables in the success…
- Conditions
- Respiratory Insufficiency, Respiratory Distress Syndrome, Adult, Chronic Obstructive Pulmonary Disease, Pulmonary Edema
- Trial name
- NCT00944437
- Testing
- Helmet, Full-face mask
- Where
- Italy
- Volunteers
- 23 people
- Sponsor
- University of Parma
COPD, COPD Exacerbation
Roflumilast in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Fixed Dose Combinations of Long-acting β2-agonist (LABA) and Inhaled Corticosteroid (ICS)
To demonstrate the additional benefit of roflumilast when added on to fixed-dose combination (FDC) LABA/ICS in the reduction of exacerbations in subjects with severe to very severe COPD.
- Conditions
- COPD, COPD Exacerbation, Lung Diseases, Respiratory Disorders
- Trial name
- NCT01443845
- Testing
- Roflumilast
- Where
- 338 sites in United States, Argentina and 15 more
- Volunteers
- 2,354 people
- Sponsor
- AstraZeneca
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