Clinical trials: Pulmonary Disease (COPD), Chronic Obstructive
Chronic Obstructive Pulmonary Disease, Alpha 1-Antitrypsin Deficiency
Effects of Different Exercise Training Modalities in Alpha-1 Antitrypsin Deficiency Patients
Pulmonary rehabilitation (PR) including exercise training is highly effective by improving health-related quality of life, exercise capacity and symptoms in patients with chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT03802357
- Testing
- Exercise training
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Schön Klinik Berchtesgadener Land
Asthma, Chronic Obstructive Pulmonary Disease
Breath Actuated Nebulizer Study Protocol
Comparison of the researchers' standard nebulizer and a breath actuated nebulizer to examine if breathing medication can be delivered more quickly and as effectively or more effectively than the standard nebulizer.
- Trial name
- NCT00382447
- Testing
- standard nebulizer, breath actuated nebulizer
- Where
- United States
- Sponsor
- Christiana Care Health Services
Chronic Obstructive Pulmonary Disease
Clinical Trial Assessing the Value of an Antibiotic Protocol Guided by Serum Procalcitonin in Acute Exacerbations of Chronic Obstructive Pulmonary Disease in Intensive Care
Investigators propose to conduct a prospective, randomized, controlled, multicenter assessing the interests of an antibiotic protocol guided by serum procalcitonin (PCT) on morbidity and mortality in patients with chronic…
- Trial name
- BPCTréa (NCT02521636)
- Testing
- Antibiotic therapy randomization, Serum PCT dosage
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Caen
Lung Neoplasms, Pulmonary Disease, Chronic Obstructive
Circulating Tumor Cells in Lung Cancer Screening
This trial is intended to evaluate the value of circulating tumor cells (CTC), in combination with unenhanced (without injection of contrast media) low dose (to limit the effective radiation dose below 1,5 mSv) chest computed…
- Trial name
- AIR (NCT02500693)
- Testing
- Isolation of circulating tumor cells (CTC) from veinous blood
- Where
- 20 sites in France
- Volunteers
- 683 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
COPD, COPD (Chronic Obstructive Pulmonary Disease)
Mobile Health Self-Management Intervention for Patient With Chronic Obstructive Pulmonary Disease
This clinical trial aims to evaluate the effectiveness of a pharmacist-led interactive mobile health intervention (serious game) in adults aged 50 years and older with chronic obstructive pulmonary disease (COPD).
- Trial name
- AERIS (NCT07469904)
- Testing
- Pharmacist-Led mHealth Serious Game, Usual Care
- Where
- Indonesia
- Volunteers
- 126 people
- Sponsor
- Universitas Katolik Widya Mandala Surabaya
Chronic Obstructive Pulmonary Disease
Patient Registry of Roflumilast In Real Life
A patient registry to capture real life data and demonstrate the performance of roflumilast (Daxas®) in a standard clinical practice.
- Trial name
- NCT02015767
- Where
- 51 sites in Bulgaria, Greece and 4 more
- Volunteers
- 1,950 people
- Sponsor
- AstraZeneca
Chronic Obstructive Airway Disease
Acapella Versus Lung Flute in Treatment of COPD Patients the Study Aims to Identify the Preference Between the Two Devices According to Treatment of COPD Patients Regarding Pulmonary Function Tests , Exercise Tolerence and Quality of Life Questionnaire,
Chronic obstructive pulmonary disease (COPD) is a prevalent and progressive condition characterized by persistent airflow limitation and chronic respiratory symptoms.
- Trial name
- NCT06801106
- Testing
- Acapella, Lung flute
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ministry of Health and Population, Egypt
COPD (Chronic Obstructive Pulmonary Disease), COPD
Dupilumab in Type 2-Inflamed COPD Across the Full Spectrum of Airflow Limitation: An Italian Multicentre Retrospective Cohort Study
This multicentre retrospective cohort study describes lung function and patient-reported outcomes in adults with chronic obstructive pulmonary disease (COPD) and type 2 inflammation who received add-on dupilumab in routine…
- Conditions
- COPD (Chronic Obstructive Pulmonary Disease), COPD, Eosinophilia
- Trial name
- DUPICENTRO (NCT07788092)
- Testing
- Dupilumab
- Where
- 6 sites in Italy
- Volunteers
- 40 people
- Sponsor
- Azienda Ospedaliera di Perugia
COPD
Comparison of 24 Hour Bronchodilator Efficacy of Tiotropium 18 mcg Delivered Via DISCAIR Versus SPIRIVA 18 µg Delivered Via HANDIHALER® in Patients With Moderate to Severe COPD
The objective of this study is to compare the bronchodilator efficacy a of tiotropium inhalation via DISCAIR (18 mcg once daily) and SPIRIVA HANDIHALER® (18 mcg once daily) in patients with moderate to severe chronic obstructive…
- Trial name
- NCT02541006
- Testing
- Tiotropium 18 mcg
- Volunteers
- 58 people
- Sponsor
- Neutec Ar-Ge San ve Tic A.Ş
Chronic Obstructive Pulmonary Disease, Smoker Lung
Lung Elastrosonography in Diagnosis and Stratification of COPD and Fibrosis
Elastosonography is an advanced ultrasound technique, nowadays available in many portable systems, allowing to measure elasticity and stiffness of parenchymatous organs.
- Trial name
- ELAS-P-1 (NCT04149652)
- Testing
- Lung Elastosonography
- Where
- Italy
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
COPD
Pharmacokinetic Interaction Study of Glycopyrrolate and Formoterol in Healthy Volunteers
This study will be carried out in healthy volunteers with the primary objective to evaluate the pharmacokinetic interaction between Glyco and Formoterol administered using a pressurised metered dose inhaler (pMDI).
- Trial name
- TRIPLE 1 (NCT01398111)
- Testing
- Glycopyrrolate + Formoterol, Glycopyrrolate, Formoterol
- Where
- Belgium
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Chiesi Farmaceutici S.p.A.
Chronic Respiratory Failure, Nutritional Depletion
IRAD2 : Patients With Respiratory Failure at Home
Title : Effects of home pulmonary rehabilitation in patients with chronic respiratory failure and nutritional depletion. This is a randomized controlled, open clinical trial with two groups.
- Trial name
- NCT00230984
- Testing
- education, Oral dietary supplements (563 kcal/d), RESPIFOR, exercises on an ergometric bicycle 3 to 5 times a week
- Where
- 8 sites in France, Switzerland
- Volunteers
- 200 people
- Sponsor
- University Hospital, Grenoble
Acute Myocardial Infarction, Diabetes Mellitus
Association of Long-term Conditions With Survival Following Heart Attack in England and Wales
This study aims to determine the extent to which pre-existing long-term conditions are associated with survival following a heart attack (acute myocardial infarction) using observational data from the UK's national heart attack…
- Conditions
- Acute Myocardial Infarction, Diabetes Mellitus, Peripheral Vascular Disease, Chronic Heart Failure
- Trial name
- NCT03037255
- Testing
- long term conditions
- Volunteers
- 693,633 people
- Sponsor
- Marlous Hall
Chronic Obstructive Pulmonary Disease, Alpha-1-antitrypsin-deficiency
Effects of Exercise Training in Chronic Obstructive Pulmonary Disease Versus Alpha-1-Antitrypsin-deficiency-patients
Chronic Obstructive Pulmonary Disease (COPD)-patients (caused by smoking-level) and Alpha-1-Antitrypsin-deficiency patients showed different developments during rehabilitation in regard to improvement of 6-minute-walking…
- Trial name
- NCT01380626
- Testing
- exercise training
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Schön Klinik Berchtesgadener Land
Chronic Obstructive Pulmonary Disease (COPD)
QVA vs. Salmeterol/Fluticasone, 52-week Exacerbation Study, FLAME (EFfect of Indacaterol Glycopyronium Vs Fluticasone Salmeterol on COPD Exacerbations)
This study will assess the efficacy, safety and tolerability of QVA149 in patients with moderate to very severe COPD.
- Trial name
- NCT01782326
- Testing
- QVA149, Long acting B2 agonist (LABA) and inhaled corticosteroid (ICS)
- Where
- 499 sites in Argentina, Austria and 41 more
- Volunteers
- 3,362 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Obstructive Pulmonary Disease
Acupuncture Combined With Pulmonary Rehabilitation: Are There Additional Benefits?
The hypothesis of this study was that acupuncture in conjunction with standard care of pulmonary rehabilitation improves outcome measures compared to pulmonary rehabilitation alone.
- Trial name
- NCT01112943
- Testing
- Acupuncture, Pulmonary Rehabilitation
- Where
- Ireland
- Volunteers
- 44 people
- Sponsor
- Beaumont Hospital
Copd
Peripheral Muscle Function in Patients With COPD
Chronic obstructive pulmonary disease (COPD) is characterized by irreversible airway obstruction and progressive deterioration of respiratory function.
- Trial name
- NCT04767126
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Chronic Obstructive Pulmonary Disease
The Effect of Maximal Strength Training on Lung Function in Patients With COPD
The purpose of this study is to investigate the effect on maximal strength training on muscle function, lung function and quality of life for patients diagnosed with COPD grade II-III (Gold scale).
- Trial name
- NCT05586399
- Testing
- Maximal strength training in COPD
- Where
- Norway
- Volunteers
- 30 people
- Sponsor
- Molde University College
COPD, Chronic Obstructive Pulmonary Disease
Melodica Orchestra for Dyspnea: Safety and Feasibility Pilot
This project seeks to pilot-test the feasibility of using a melodica training program to teach pursed lip breathing for Veterans with chronic obstructive pulmonary disease (COPD) with moderate to severe dyspnea (shortness of…
- Conditions
- COPD, Chronic Obstructive Pulmonary Disease, Dyspnea, Breathlessness
- Trial name
- MELODY (NCT03653104)
- Testing
- Melodica Intervention, Pulmonary Health Education
- Where
- United States
- Sponsor
- VA Quality Enhancement Research Intiative
Heart Failure, Pulmonary Disease, Chronic Obstructive
Advancing Symptom Alleviation With Palliative Treatment
Chronic heart failure (CHF), chronic obstructive pulmonary disease (COPD), and interstitial lung disease (i.e., pulmonary fibrosis) are common serious illnesses.
- Conditions
- Heart Failure, Pulmonary Disease, Chronic Obstructive, Emphysema, Pulmonary Fibrosis, Interstitial Lung Disease
- Trial name
- ADAPT (NCT02713347)
- Testing
- ADAPT Intervention
- Where
- 2 sites in United States
- Volunteers
- 306 people
- Sponsor
- VA Office of Research and Development
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